메뉴 건너뛰기




Volumn 17, Issue 3, 2011, Pages 254-259

Should cerebral microbleeds on magnetic resonance imaging contraindicate thrombolysis in patients with ischaemic stroke?. A systematic review of the evidence

Author keywords

Cerebral microbleeds; Magnetic resonance imaging; Stroke; Thrombolysis

Indexed keywords

BLOOD CLOT LYSIS; BRAIN HEMORRHAGE; HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PREVALENCE; PRIORITY JOURNAL; REVIEW; RISK FACTOR; STROKE; SYSTEMATIC REVIEW;

EID: 79959579745     PISSN: 10788174     EISSN: 15322831     Source Type: Journal    
DOI: 10.1016/j.radi.2011.04.003     Document Type: Review
Times cited : (1)

References (49)
  • 3
    • 79959584522 scopus 로고    scopus 로고
    • Alterations in brain function
    • Lippincott Williams & Wilkins, C. Porth (Ed.)
    • Book D. Alterations in brain function. Essentials of pathophysiology 2004, Lippincott Williams & Wilkins. C. Porth (Ed.).
    • (2004) Essentials of pathophysiology
    • Book, D.1
  • 5
    • 33745949968 scopus 로고    scopus 로고
    • MRI versus CT-based thrombolysis treatment within and beyond the 3 h time window after stroke onset: a cohort study
    • England
    • Kohrmann M., Juttler E., Fiebach J.B., et al. MRI versus CT-based thrombolysis treatment within and beyond the 3 h time window after stroke onset: a cohort study. Lancet Neurol 2006, 5:661-667. England.
    • (2006) Lancet Neurol , vol.5 , pp. 661-667
    • Kohrmann, M.1    Juttler, E.2    Fiebach, J.B.3
  • 6
    • 10744232087 scopus 로고    scopus 로고
    • Stroke magnetic resonance imaging is accurate in hyperacute intracerebral hemorrhage: a multicenter study on the validity of stroke imaging
    • Fiebach J.B., Schellinger P.D., Gass A., et al. Stroke magnetic resonance imaging is accurate in hyperacute intracerebral hemorrhage: a multicenter study on the validity of stroke imaging. Stroke Feb 2004, 35(2):502-506.
    • (2004) Stroke , vol.35 , Issue.2 , pp. 502-506
    • Fiebach, J.B.1    Schellinger, P.D.2    Gass, A.3
  • 7
    • 34547713221 scopus 로고    scopus 로고
    • The importance of specific diagnosis in stroke patient management
    • Cambridge University Press, S. Davis, M. Fisher, S. Warach (Eds.)
    • Fink J.N., Caplan L.R. The importance of specific diagnosis in stroke patient management. Magnetic resonance imaging in stroke 2003, Cambridge University Press. S. Davis, M. Fisher, S. Warach (Eds.).
    • (2003) Magnetic resonance imaging in stroke
    • Fink, J.N.1    Caplan, L.R.2
  • 8
    • 33846363871 scopus 로고    scopus 로고
    • Magnetic resonance imaging and computed tomography in emergency assessment of patients with suspected acute stroke: a prospective comparison
    • 27
    • Chalela J.A., Kidwell C.S., Nentwich L.M., et al. Magnetic resonance imaging and computed tomography in emergency assessment of patients with suspected acute stroke: a prospective comparison. Lancet Jan 27 2007, 369(9558):293-298.
    • (2007) Lancet , vol.369 , Issue.9558 , pp. 293-298
    • Chalela, J.A.1    Kidwell, C.S.2    Nentwich, L.M.3
  • 9
    • 0035130531 scopus 로고    scopus 로고
    • Risk factors for severe hemorrhagic transformation in ischemic stroke patients treated with recombinant tissue plasminogen activator: a secondary analysis of the European-Australasian Acute Stroke Study (ECASS II)
    • Larrue V., von Kummer R.R., Muller A., Bluhmki E. Risk factors for severe hemorrhagic transformation in ischemic stroke patients treated with recombinant tissue plasminogen activator: a secondary analysis of the European-Australasian Acute Stroke Study (ECASS II). Stroke Feb 2001, 32(2):438-441.
    • (2001) Stroke , vol.32 , Issue.2 , pp. 438-441
    • Larrue, V.1    von Kummer, R.R.2    Muller, A.3    Bluhmki, E.4
  • 10
    • 53149124792 scopus 로고    scopus 로고
    • Intracerebral haemorrhage after thrombolysis for acute ischaemic stroke: an update
    • Derex L., Nighoghossian N. Intracerebral haemorrhage after thrombolysis for acute ischaemic stroke: an update. J Neurol Neurosurg Psychiatr Oct 2008, 79(10):1093-1099.
    • (2008) J Neurol Neurosurg Psychiatr , vol.79 , Issue.10 , pp. 1093-1099
    • Derex, L.1    Nighoghossian, N.2
  • 11
    • 38949157989 scopus 로고    scopus 로고
    • Imaging of intracranial haemorrhage
    • Kidwell C.S., Wintermark M. Imaging of intracranial haemorrhage. Lancet Neurol Mar 2008, 7(3):256-267.
    • (2008) Lancet Neurol , vol.7 , Issue.3 , pp. 256-267
    • Kidwell, C.S.1    Wintermark, M.2
  • 12
    • 58649115794 scopus 로고    scopus 로고
    • Cerebral microbleeds: a guide to detection and interpretation
    • Greenberg S.M., Vernooij M.W., Cordonnier C., et al. Cerebral microbleeds: a guide to detection and interpretation. Lancet Neurol Feb 2009, 8(2):165-174.
    • (2009) Lancet Neurol , vol.8 , Issue.2 , pp. 165-174
    • Greenberg, S.M.1    Vernooij, M.W.2    Cordonnier, C.3
  • 14
    • 0033364292 scopus 로고    scopus 로고
    • Histopathologic analysis of foci of signal loss on gradient-echo T2*-weighted MR images in patients with spontaneous intracerebral hemorrhage: evidence of microangiopathy-related microbleeds
    • Fazekas F., Kleinert R., Roob G., et al. Histopathologic analysis of foci of signal loss on gradient-echo T2*-weighted MR images in patients with spontaneous intracerebral hemorrhage: evidence of microangiopathy-related microbleeds. AJNR Am J Neuroradiol Apr 1999, 20(4):637-642.
    • (1999) AJNR Am J Neuroradiol , vol.20 , Issue.4 , pp. 637-642
    • Fazekas, F.1    Kleinert, R.2    Roob, G.3
  • 15
    • 34249802129 scopus 로고    scopus 로고
    • Spontaneous brain microbleeds: systematic review, subgroup analyses and standards for study design and reporting
    • England
    • Cordonnier C., Al-Shahi Salman R., Wardlaw J. Spontaneous brain microbleeds: systematic review, subgroup analyses and standards for study design and reporting. Brain 2007, 130:1988-2003. England.
    • (2007) Brain , vol.130 , pp. 1988-2003
    • Cordonnier, C.1    Al-Shahi Salman, R.2    Wardlaw, J.3
  • 16
    • 0036905152 scopus 로고    scopus 로고
    • Low concentration of serum total cholesterol is associated with multifocal signal loss lesions on gradient-echo magnetic resonance imaging: analysis of risk factors for multifocal signal loss lesions
    • Lee S.H., Bae H.J., Yoon B.W., Kim H., Kim D.E., Roh J.K. Low concentration of serum total cholesterol is associated with multifocal signal loss lesions on gradient-echo magnetic resonance imaging: analysis of risk factors for multifocal signal loss lesions. Stroke Dec 2002, 33(12):2845-2849.
    • (2002) Stroke , vol.33 , Issue.12 , pp. 2845-2849
    • Lee, S.H.1    Bae, H.J.2    Yoon, B.W.3    Kim, H.4    Kim, D.E.5    Roh, J.K.6
  • 17
    • 58649121700 scopus 로고    scopus 로고
    • Improving interrater agreement about brain microbleeds: development of the Brain Observer MicroBleed Scale (BOMBS)
    • Cordonnier C., Potter G.M., Jackson C.A., et al. improving interrater agreement about brain microbleeds: development of the Brain Observer MicroBleed Scale (BOMBS). Stroke Jan 2009, 40(1):94-99.
    • (2009) Stroke , vol.40 , Issue.1 , pp. 94-99
    • Cordonnier, C.1    Potter, G.M.2    Jackson, C.A.3
  • 18
    • 73349095046 scopus 로고    scopus 로고
    • The Microbleed Anatomical Rating Scale (MARS): reliability of a tool to map brain microbleeds
    • 24
    • Gregoire S.M., Chaudhary U.J., Brown M.M., et al. The Microbleed Anatomical Rating Scale (MARS): reliability of a tool to map brain microbleeds. Neurology Nov 24 2009, 73(21):1759-1766.
    • (2009) Neurology , vol.73 , Issue.21 , pp. 1759-1766
    • Gregoire, S.M.1    Chaudhary, U.J.2    Brown, M.M.3
  • 19
    • 58549108211 scopus 로고    scopus 로고
    • Risk vs benefit of anti-thrombotic therapy in ischaemic stroke patients with cerebral microbleeds
    • Soo Y.O., Yang S.R., Lam W.W., et al. Risk vs benefit of anti-thrombotic therapy in ischaemic stroke patients with cerebral microbleeds. J Neurol Nov 2008, 255(11):1679-1686.
    • (2008) J Neurol , vol.255 , Issue.11 , pp. 1679-1686
    • Soo, Y.O.1    Yang, S.R.2    Lam, W.W.3
  • 20
    • 12844272119 scopus 로고    scopus 로고
    • Magnetic resonance imaging criteria for thrombolysis in acute cerebral infarct
    • Hjort N., Butcher K., Davis S.M., et al. Magnetic resonance imaging criteria for thrombolysis in acute cerebral infarct. Stroke Feb 2005, 36(2):388-397.
    • (2005) Stroke , vol.36 , Issue.2 , pp. 388-397
    • Hjort, N.1    Butcher, K.2    Davis, S.M.3
  • 24
    • 18244379632 scopus 로고    scopus 로고
    • Magnetic resonance imaging detection of microbleeds before thrombolysis: an emerging application
    • Kidwell C.S., Saver J.L., Villablanca J.P., et al. Magnetic resonance imaging detection of microbleeds before thrombolysis: an emerging application. Stroke Jan 2002, 33(1):95-98.
    • (2002) Stroke , vol.33 , Issue.1 , pp. 95-98
    • Kidwell, C.S.1    Saver, J.L.2    Villablanca, J.P.3
  • 25
    • 18344372562 scopus 로고    scopus 로고
    • Old microbleeds are a potential risk factor for cerebral bleeding after ischemic stroke: a gradient-echo T2*-weighted brain MRI study
    • Nighoghossian N., Hermier M., Adeleine P., et al. Old microbleeds are a potential risk factor for cerebral bleeding after ischemic stroke: a gradient-echo T2*-weighted brain MRI study. Stroke Mar 2002, 33(3):735-742.
    • (2002) Stroke , vol.33 , Issue.3 , pp. 735-742
    • Nighoghossian, N.1    Hermier, M.2    Adeleine, P.3
  • 26
    • 33646508162 scopus 로고    scopus 로고
    • Pathophysiology and treatment of stroke in sickle-cell disease: present and future
    • Switzer J.A., Hess D.C., Nichols F.T., Adams R.J. Pathophysiology and treatment of stroke in sickle-cell disease: present and future. Lancet Neurol Jun 2006, 5(6):501-512.
    • (2006) Lancet Neurol , vol.5 , Issue.6 , pp. 501-512
    • Switzer, J.A.1    Hess, D.C.2    Nichols, F.T.3    Adams, R.J.4
  • 27
    • 33846373609 scopus 로고    scopus 로고
    • Validity of indirect comparisons in meta-analysis
    • author reply 271
    • Caldwell D.M., Gibb D.M., Ades A.E. Validity of indirect comparisons in meta-analysis. Lancet Jan 27 2007, 369(9558):270. author reply 271.
    • (2007) Lancet , vol.369 , Issue.9558 , pp. 270
    • Caldwell, D.M.1    Gibb, D.M.2    Ades, A.E.3
  • 28
    • 0030720013 scopus 로고    scopus 로고
    • Meta-analysis: principles and procedures
    • Egger M., Smith G.D., Phillips A.N. Meta-analysis: principles and procedures. BMJ Dec 6 1997, 315(7121):1533-1537.
    • (1997) BMJ , vol.315 , Issue.7121 , pp. 1533-1537
    • Egger, M.1    Smith, G.D.2    Phillips, A.N.3
  • 29
    • 78649923350 scopus 로고    scopus 로고
    • Health Care Practice Research Development Unit, [accessed 29.04.08.]
    • Evaluation tool for quantitative research studies 2005, Health Care Practice Research Development Unit, [accessed 29.04.08.]. http://www.fhsc.salford.ac.uk/hcprdu/quantitative.htm.
    • (2005) Evaluation tool for quantitative research studies
  • 30
    • 79959595466 scopus 로고    scopus 로고
    • National Patient Safety Agency. Standard Operating Procedures for Research Ethics Committees. [accessed 03.05.09.]
    • National Patient Safety Agency. Standard Operating Procedures for Research Ethics Committees. [accessed 03.05.09.]. http://www.nres.npsa.nhs.uk/news-and-publications/publications/standard-operating-procedures/.
  • 31
    • 11144356036 scopus 로고    scopus 로고
    • Thrombolysis for ischemic stroke in patients with old microbleeds on pretreatment MRI
    • Derex L., Nighoghossian N., Hermier M., et al. Thrombolysis for ischemic stroke in patients with old microbleeds on pretreatment MRI. Cerebrovasc Dis 2004, 17(2-3):238-241.
    • (2004) Cerebrovasc Dis , vol.17 , Issue.2-3 , pp. 238-241
    • Derex, L.1    Nighoghossian, N.2    Hermier, M.3
  • 32
    • 27144503010 scopus 로고    scopus 로고
    • Clinical importance of microbleeds in patients receiving IV thrombolysis
    • 25
    • Kakuda W., Thijs V.N., Lansberg M.G., et al. Clinical importance of microbleeds in patients receiving IV thrombolysis. Neurology Oct 25 2005, 65(8):1175-1178.
    • (2005) Neurology , vol.65 , Issue.8 , pp. 1175-1178
    • Kakuda, W.1    Thijs, V.N.2    Lansberg, M.G.3
  • 33
    • 33745537994 scopus 로고    scopus 로고
    • Multiple cerebral microbleeds in hyperacute ischemic stroke: impact on prevalence and severity of early hemorrhagic transformation after thrombolytic treatment
    • Kim H.S., Lee D.H., Ryu C.W., et al. Multiple cerebral microbleeds in hyperacute ischemic stroke: impact on prevalence and severity of early hemorrhagic transformation after thrombolytic treatment. AJR Am J Roentgenol May 2006, 186(5):1443-1449.
    • (2006) AJR Am J Roentgenol , vol.186 , Issue.5 , pp. 1443-1449
    • Kim, H.S.1    Lee, D.H.2    Ryu, C.W.3
  • 34
    • 34848904882 scopus 로고    scopus 로고
    • Bleeding risk analysis in stroke imaging before thromboLysis (BRASIL): pooled analysis of T2*-weighted magnetic resonance imaging data from 570 p.tients
    • Fiehler J., Albers G.W., Boulanger J.M., et al. Bleeding risk analysis in stroke imaging before thromboLysis (BRASIL): pooled analysis of T2*-weighted magnetic resonance imaging data from 570 p.tients. Stroke Oct 2007, 38(10):2738-2744.
    • (2007) Stroke , vol.38 , Issue.10 , pp. 2738-2744
    • Fiehler, J.1    Albers, G.W.2    Boulanger, J.M.3
  • 35
    • 70349496210 scopus 로고    scopus 로고
    • Combination of T2*W and FLAIR abnormalities for the prediction of parenchymal hematoma following thrombolytic therapy in 100 stroke patients
    • Fiehler J., Siemonsen S., Thomalla G., Illies T., Kucinski T. Combination of T2*W and FLAIR abnormalities for the prediction of parenchymal hematoma following thrombolytic therapy in 100 stroke patients. J Neuroimaging Oct 2009, 19(4):311-316.
    • (2009) J Neuroimaging , vol.19 , Issue.4 , pp. 311-316
    • Fiehler, J.1    Siemonsen, S.2    Thomalla, G.3    Illies, T.4    Kucinski, T.5
  • 36
    • 0036284563 scopus 로고    scopus 로고
    • Microbleeding on MRI as a marker for hemorrhage after stroke thrombolysis
    • Coutts S., Frayne R., Sevick R., Demchuk A. Microbleeding on MRI as a marker for hemorrhage after stroke thrombolysis. Stroke Jun 2002, 33(6):1457-1458.
    • (2002) Stroke , vol.33 , Issue.6 , pp. 1457-1458
    • Coutts, S.1    Frayne, R.2    Sevick, R.3    Demchuk, A.4
  • 37
    • 0348010243 scopus 로고    scopus 로고
    • Multiple cerebral microbleeds: MRI marker of a diffuse hemorrhage-prone state
    • Chalela J.A., Kang D.W., Warach S. Multiple cerebral microbleeds: MRI marker of a diffuse hemorrhage-prone state. J Neuroimaging Jan 2004, 14(1):54-57.
    • (2004) J Neuroimaging , vol.14 , Issue.1 , pp. 54-57
    • Chalela, J.A.1    Kang, D.W.2    Warach, S.3
  • 38
    • 24644450124 scopus 로고    scopus 로고
    • MRI screening before standard tissue plasminogen activator therapy is feasible and safe
    • Kang D.W., Chalela J.A., Dunn W., Warach S. MRI screening before standard tissue plasminogen activator therapy is feasible and safe. Stroke Sep 2005, 36(9):1939-1943.
    • (2005) Stroke , vol.36 , Issue.9 , pp. 1939-1943
    • Kang, D.W.1    Chalela, J.A.2    Dunn, W.3    Warach, S.4
  • 39
    • 79959623604 scopus 로고    scopus 로고
    • Annual meeting abstracts
    • American Society of Neuroimaging 2007
    • Annual meeting abstracts. J Neuroimaging 2007, 17(1):89-104. American Society of Neuroimaging 2007.
    • (2007) J Neuroimaging , vol.17 , Issue.1 , pp. 89-104
  • 40
    • 0347949544 scopus 로고    scopus 로고
    • Assessing the quality of research
    • England
    • Glasziou P., Vandenbroucke J.P., Chalmers I. Assessing the quality of research. BMJ 2004, 328:39-41. England.
    • (2004) BMJ , vol.328 , pp. 39-41
    • Glasziou, P.1    Vandenbroucke, J.P.2    Chalmers, I.3
  • 42
    • 30544452135 scopus 로고    scopus 로고
    • Comparative safety and efficacy of urokinase and recombinant tissue plasminogen activator for peripheral arterial occlusion: a meta-analysis
    • Sander S., White C.M., Coleman C.I. Comparative safety and efficacy of urokinase and recombinant tissue plasminogen activator for peripheral arterial occlusion: a meta-analysis. Pharmacotherapy Jan 2006, 26(1):51-60.
    • (2006) Pharmacotherapy , vol.26 , Issue.1 , pp. 51-60
    • Sander, S.1    White, C.M.2    Coleman, C.I.3
  • 43
    • 59849092089 scopus 로고    scopus 로고
    • Risk of symptomatic intracerebral hemorrhage in patients treated with intra-arterial thrombolysis
    • Singer O.C., Berkefeld J., Lorenz M.W., et al. Risk of symptomatic intracerebral hemorrhage in patients treated with intra-arterial thrombolysis. Cerebrovasc Dis 2009, 27(4):368-374.
    • (2009) Cerebrovasc Dis , vol.27 , Issue.4 , pp. 368-374
    • Singer, O.C.1    Berkefeld, J.2    Lorenz, M.W.3
  • 44
    • 47649112761 scopus 로고    scopus 로고
    • Risk of thrombolysis-related hemorrhage associated with microbleed presence
    • author reply e116
    • Vernooij M.W., van der Lugt A., Breteler M.M. Risk of thrombolysis-related hemorrhage associated with microbleed presence. Stroke Jul 2008, 39(7):e115. author reply e116.
    • (2008) Stroke , vol.39 , Issue.7
    • Vernooij, M.W.1    van der Lugt, A.2    Breteler, M.M.3
  • 45
    • 33646179811 scopus 로고    scopus 로고
    • Silent microbleeds are associated with volume of primary intracerebral hemorrhage
    • Lee S.H., Kim B.J., Roh J.K. Silent microbleeds are associated with volume of primary intracerebral hemorrhage. Neurology Feb 14 2006, 66(3):430-432.
    • (2006) Neurology , vol.66 , Issue.3 , pp. 430-432
    • Lee, S.H.1    Kim, B.J.2    Roh, J.K.3
  • 46
    • 0034993089 scopus 로고    scopus 로고
    • Hemorrhagic transformation of ischemic brain tissue: asymptomatic or symptomatic?
    • Berger C., Fiorelli M., Steiner T. Hemorrhagic transformation of ischemic brain tissue: asymptomatic or symptomatic?. Stroke 2002, 33(6):1330-1335.
    • (2002) Stroke , vol.33 , Issue.6 , pp. 1330-1335
    • Berger, C.1    Fiorelli, M.2    Steiner, T.3
  • 47
    • 84862556395 scopus 로고    scopus 로고
    • National Institute of Neurological Disorders and Stroke, 08/04/2009
    • NIH stroke scale National Institute of Neurological Disorders and Stroke, 08/04/2009. http://www.ninds.nih.gov/doctors/NIH_Stroke_Scale.pdf.
    • NIH stroke scale
  • 48
    • 0343118114 scopus 로고    scopus 로고
    • Intracerebral hemorrhage after intravenous t-PA therapy for ischemic stroke
    • The NINDS t-PA Stroke Study Group
    • Intracerebral hemorrhage after intravenous t-PA therapy for ischemic stroke. Stroke Nov 1997, 28(11):2109-2118. The NINDS t-PA Stroke Study Group.
    • (1997) Stroke , vol.28 , Issue.11 , pp. 2109-2118
  • 49
    • 0032539329 scopus 로고    scopus 로고
    • Understanding controlled trials. Why are randomised controlled trials important?
    • Sibbald B., Roland M. Understanding controlled trials. Why are randomised controlled trials important?. BMJ Jan 17 1998, 316(7126):201.
    • (1998) BMJ , vol.316 , Issue.7126 , pp. 201
    • Sibbald, B.1    Roland, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.