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Volumn 105, Issue 9, 2011, Pages 1161-1172
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Prochelators triggered by hydrogen peroxide provide hexadentate iron coordination to impede oxidative stress
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Author keywords
Chelation therapy; Copper; Fenton chemistry; Iron; Oxidative stress; Reactive oxygen species
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Indexed keywords
CHELATING AGENT;
COPPER;
HYDROGEN PEROXIDE;
HYDROXYL RADICAL;
IRON;
METAL ION;
TRIS[(2 BORONIC ACID BENZYL) 2 AMINOETHYL]AMINE;
TRIS[(2 HYDROXYBENZOYL) 2 AMINOETHYL]AMINE;
TRIS[(2 HYDROXYBENZYL) 2 AMINOETHYL]AMINE;
TRIS[(SALICYLIDENEAMINO)ETHYL]AMINE;
TRIS[[2 (4,4,5,5 TETRAMETHYL 1,3,2 DIOXABOROLAN 2 YL)BENZOYL] 2 AMINOETHYL]AMINE;
TRIS[[2 (4,4,5,5 TETRAMETHYL 1,3,2 DIOXABOROLAN 2 YL)BENZYLIDEN] 2 AMINOETHYL]AMINE;
UNCLASSIFIED DRUG;
ARTICLE;
BINDING AFFINITY;
BINDING SITE;
CELL DEATH;
CELL PROTECTION;
CHEMICAL INTERACTION;
CONCENTRATION RESPONSE;
CONTROLLED STUDY;
DRUG BINDING;
DRUG STRUCTURE;
HUMAN;
HUMAN CELL;
HYDROXYLATION;
IN VITRO STUDY;
IRON CHELATION;
NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;
OXIDATIVE STRESS;
PH;
PIGMENT EPITHELIUM;
X RAY CRYSTALLOGRAPHY;
AMINES;
ANTIOXIDANTS;
BORON COMPOUNDS;
CELL DEATH;
CELL SURVIVAL;
CHELATING AGENTS;
COPPER;
CRYSTALLOGRAPHY, X-RAY;
EPITHELIAL CELLS;
HYDROGEN PEROXIDE;
HYDROXYL RADICAL;
IRON;
KINETICS;
LIGANDS;
MAGNETIC RESONANCE SPECTROSCOPY;
OXIDATION-REDUCTION;
OXIDATIVE STRESS;
PRODRUGS;
RETINAL PIGMENT EPITHELIUM;
SPECTROPHOTOMETRY, ULTRAVIOLET;
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EID: 79959553824
PISSN: 01620134
EISSN: 18733344
Source Type: Journal
DOI: 10.1016/j.jinorgbio.2011.05.023 Document Type: Article |
Times cited : (28)
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References (50)
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