Microcalorimetric study of the adsorption of PEGylated lysozyme on a strong cation exchange resin

Journal of Chromatography A

Volumn 1218, Issue 29, 2011, Pages 4720-4726

  Blaschke, Tim ^a   Varon, Jefferson ^a   Werner, Albert ^a   Hasse, Hans ^a  

^a University of Koblenz Landau   (Germany)

Author keywords

Endothermal; Enthalpy of adsorption; Exothermal; Ion exchange chromatography; Isothermal titration calorimetry; PEGylation; Protein adsorption; Protein purification; Thermodynamic analysis

Indexed keywords

ENDOTHERMAL; ENTHALPY OF ADSORPTION; EXOTHERMAL; ION EXCHANGE CHROMATOGRAPHY; ISOTHERMAL TITRATION CALORIMETRY; PEGYLATION; PROTEIN ADSORPTION; PROTEIN PURIFICATION; THERMODYNAMIC ANALYSIS;

ADSORPTION ISOTHERMS; CALORIMETRY; CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; ENTHALPY; ENZYMES; ION CHROMATOGRAPHY; ION EXCHANGE; LOADING; PROTEINS; SODIUM CHLORIDE; THERMOANALYSIS; TITRATION;

ADSORPTION;

LYSOZYME; PEGYLATED LYSOZYME; RESIN; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ADSORPTION; ARTICLE; BINDING AFFINITY; CATION EXCHANGE; CONTROLLED STUDY; ELUTION; ENTHALPY; ENTROPY; ISOTHERMAL TITRATION CALORIMETRY; MICROCALORIMETRY; MOLECULAR MECHANICS; PRIORITY JOURNAL; PROTEIN PURIFICATION; QUANTITATIVE ANALYSIS; SEPARATION TECHNIQUE; THERMODYNAMICS;

ADSORPTION; CALORIMETRY; CATION EXCHANGE RESINS; CATIONS; CHROMATOGRAPHY, ION EXCHANGE; HYDROGEN-ION CONCENTRATION; MODELS, MOLECULAR; MURAMIDASE; POLYETHYLENE GLYCOLS; SODIUM CHLORIDE; TEMPERATURE; THERMODYNAMICS;

EID: 79959544414     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2011.05.063     Document Type: Article

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