메뉴 건너뛰기




Volumn 29, Issue 1, 2011, Pages 62-65

Biliary bicarbonate secretion constitutes a protective mechanism against bile acid-induced injury in man

Author keywords

Apoptosis; Bile acids; Cholangiocyte; HCO 3 ; Primary biliary cirrhosis

Indexed keywords

BICARBONATE; BILE ACID CONJUGATE; CASPASE 3; CASPASE 7; CHENODEOXYCHOLIC ACID;

EID: 79959525959     PISSN: 02572753     EISSN: 14219875     Source Type: Journal    
DOI: 10.1159/000324687     Document Type: Conference Paper
Times cited : (25)

References (20)
  • 1
    • 0004625655 scopus 로고
    • Mechanisms of bile secretion and hepatic transport
    • Andreoli TE, Hoffman JF, Fanestil DD, Schultz SG (eds) New York, Plenum Publishing Corporation
    • Boyer JL: Mechanisms of bile secretion and hepatic transport; in Andreoli TE, Hoffman JF, Fanestil DD, Schultz SG (eds): Physiology of Membrane Disorders. New York, Plenum Publishing Corporation, 1986, pp 609-636.
    • (1986) Physiology of Membrane Disorders , pp. 609-636
    • Boyer, J.L.1
  • 2
    • 55549146529 scopus 로고    scopus 로고
    • Genetic factors of susceptibility and of severity in primary biliary cirrhosis
    • Poupon R, Ping C, Chretien Y, et al: Genetic factors of susceptibility and of severity in primary biliary cirrhosis. J Hepatol 2008; 49: 1038-1045.
    • (2008) J Hepatol , vol.49 , pp. 1038-1045
    • Poupon, R.1    Ping, C.2    Chretien, Y.3
  • 3
    • 0027325467 scopus 로고
    • Abnormal expression of anion exchanger genes in primary biliary cirrhosis
    • Prieto J, Qian C, Garcia N, Diez J, Medina JF: Abnormal expression of anion exchanger genes in primary biliary cirrhosis. Gastroenterology 1993; 105:572-578. (Pubitemid 23213546)
    • (1993) Gastroenterology , vol.105 , Issue.2 , pp. 572-578
    • Prieto, J.1    Qian, C.2    Garcia, N.3    Diez, J.4    Medina, J.F.5
  • 4
    • 0031021891 scopus 로고    scopus 로고
    • Decreased anion exchanger 2 immunoreactivity in the liver of patients with primary biliary cirrhosis
    • Medina JF, Martinez A, Vazquez JJ, Prieto J: Decreased anion exchanger 2 immunoreactivity in the liver of patients with primary biliary cirrhosis. Hepatology 1997; 25:12-17. (Pubitemid 27014978)
    • (1997) Hepatology , vol.25 , Issue.1 , pp. 12-17
    • Medina, J.F.1    Martinez-Anso, E.2    Vazquez, J.J.3    Prieto, J.4
  • 5
    • 0033033458 scopus 로고    scopus 로고
    • Assessment of biliary bicarbonate secretion in humans by positron emission tomography
    • DOI 10.1016/S0016-5085(99)70564-0
    • Prieto J, Garcia N, Marti-Climent JM, Penuelas I, Richter JA, Medina JF: Assessment of biliary bicarbonate secretion in humans by positron emission tomography. Gastroenterology 1999; 117: 167-172. (Pubitemid 29297634)
    • (1999) Gastroenterology , vol.117 , Issue.1 , pp. 167-172
    • Prieto, J.1    Garcia, N.2    Marti-Climent, J.M.3    Penuelas, I.4    Richter, J.A.5    Medina, J.F.6
  • 7
    • 55549140795 scopus 로고    scopus 로고
    • New light on anion exchangers in primary biliary cirrhosis
    • Beuers U, Oude-Elferink RP: New light on anion exchangers in primary biliary cirrhosis. J Hepatol 2008; 49:881-883.
    • (2008) J Hepatol , vol.49 , pp. 881-883
    • Beuers, U.1    Oude-Elferink, R.P.2
  • 8
    • 77957940106 scopus 로고    scopus 로고
    • The biliary HCO(3)(-) umbrella: A unifying hypothesis on pathogenetic and therapeutic aspects of fibrosing cholangiopathies
    • Beuers U, Hohenester S, De Buy Wenniger LJ, Kremer AE, Jansen PL, Elferink RP: The biliary HCO(3)(-) umbrella: a unifying hypothesis on pathogenetic and therapeutic aspects of fibrosing cholangiopathies. Hepatology 2010; 52:1489-1496.
    • (2010) Hepatology , vol.52 , pp. 1489-1496
    • Beuers, U.1    Hohenester, S.2    De Buy Wenniger, L.J.3    Kremer, A.E.4    Jansen, P.L.5    Elferink, R.P.6
  • 10
    • 65649124573 scopus 로고    scopus 로고
    • Bile-acid-induced cell injury and protection
    • Perez MJ, Briz O: Bile-acid-induced cell injury and protection. World J Gastroenterol 2009; 15:1677-1689.
    • (2009) World J Gastroenterol , vol.15 , pp. 1677-1689
    • Perez, M.J.1    Briz, O.2
  • 11
    • 0027227827 scopus 로고
    • Glycochenodeoxycholate-induced lethal hepatocellular injury in rat hepatocytes. Role of ATP depletion and cytosolic free calcium
    • Spivey JR, Bronk SF, Gores GJ: Glycocheno-deoxycholate-induced lethal hepatocellular injury in rat hepatocytes. Role of ATP depletion and cytosolic free calcium. J Clin Invest 1993; 92:17-24. (Pubitemid 23208976)
    • (1993) Journal of Clinical Investigation , vol.92 , Issue.1 , pp. 17-24
    • Spivey, J.R.1    Bronk, S.F.2    Gores, G.J.3
  • 12
    • 77957338101 scopus 로고    scopus 로고
    • Phosphatidylinositol-3-kinase p110gamma contributes to bile salt-induced apoptosis in primary rat hepatocytes and human hepatoma cells
    • Hohenester S, Gates A, Wimmer R, et al: Phosphatidylinositol-3-kinase p110gamma contributes to bile salt-induced apoptosis in primary rat hepatocytes and human hepatoma cells. J Hepatol 2010; 53: 918 - 926.
    • (2010) J Hepatol , vol.53 , pp. 918-926
    • Hohenester, S.1    Gates, A.2    Wimmer, R.3
  • 13
    • 66149115985 scopus 로고    scopus 로고
    • Bile acids: Trying to understand their chemistry and biology with the hope of helping patients
    • Hofmann AF: Bile acids: trying to understand their chemistry and biology with the hope of helping patients. Hepatology 2009; 49:1403-1418.
    • (2009) Hepatology , vol.49 , pp. 1403-1418
    • Hofmann, A.F.1
  • 14
    • 0029920858 scopus 로고    scopus 로고
    • Carrier-mediated jejunal absorption of conjugated bile acids in the guinea pig
    • DOI 10.1053/gast.1996.v110.pm8612999
    • Amelsberg A, Schteingart CD, Ton-Nu HT, Hofmann AF: Carrier-mediated jejunal absorpt ion of conjugated bile acids in the guinea pig. Gastroenterology 1996; 110: 1098-1106. (Pubitemid 26113750)
    • (1996) Gastroenterology , vol.110 , Issue.4 , pp. 1098-1106
    • Amelsberg, A.1    Schteingart, C.D.2    Ton-Nu, H.-T.3    Hofmann, A.F.4
  • 15
    • 77956799374 scopus 로고
    • Physical-chemical properties of bile acids and their salts
    • Danielsson H, Sjövall J (eds) Amsterdam, Elsevier
    • Carey MC: Physical-chemical properties of bile acids and their salts; in Danielsson H, Sjövall J (eds): Sterols and Bile Acids. Amsterdam, Elsevier, 1985, pp 345-403.
    • (1985) Sterols and Bile Acids , pp. 345-403
    • Carey, M.C.1
  • 16
    • 0016803925 scopus 로고
    • Effect of pH on bile salt injury to mouse gastric mucosa. A light- and electron-microscopic study
    • Eastwood GL: Effect of pH on bile salt injury to mouse gastric mucosa. A light- and electron-microscopic study. Gastroenterology 1975; 68:1456-1465.
    • (1975) Gastroenterology , vol.68 , pp. 1456-1465
    • Eastwood, G.L.1
  • 19
    • 77957877682 scopus 로고    scopus 로고
    • Mutational characterization of the bile acid receptor TGR5 in primary sclerosing cholangitis
    • Hov JR, Keitel V, Laerdahl JK, et al: Mutational characterization of the bile acid receptor TGR5 in primary sclerosing cholangitis. PLoS ONE 2010; 5:e12403.
    • (2010) PLoS ONE , vol.5
    • Hov, J.R.1    Keitel, V.2    Laerdahl, J.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.