Enhanced vulnerability for Streptococcus pneumoniae sepsis during asplenia is determined by the bacterial capsule

Immunobiology

Volumn 216, Issue 8, 2011, Pages 863-870

  Lammers, Adriana J ^a,b   de Porto, Alexander P ^a,b   Florquin, Sandrine ^c   de Boer, Onno J ^c   Bootsma, Hester J ^d   Hermans, Peter W ^d   van der Poll, Tom ^a,b  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b Center for Experimental and Molecular Medicine   (Netherlands)

^c Department of Pathology ^*  (Netherlands)

^d RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Capsule; Pneumonia; Sepsis; Splenectomy; Streptococcus pneumoniae

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 6; LACTATE DEHYDROGENASE; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPLENIA; BACTERIAL GROWTH; BACTERIAL MEMBRANE; BACTERIAL STRAIN; BACTERIAL TRANSMISSION; BACTERIAL VIRULENCE; BACTERIUM MUTANT; CONTROLLED STUDY; HIGH RISK POPULATION; HOST RESISTANCE; INFECTION SENSITIVITY; INFLAMMATION; LUNG PARENCHYMA; MALE; MORTALITY; MOUSE; NONHUMAN; PNEUMOCOCCAL INFECTION; PNEUMONIA; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SEPSIS; SPLENECTOMY; STRAIN DIFFERENCE; STREPTOCOCCUS PNEUMONIAE; SYSTEMIC INFLAMMATION;

ADMINISTRATION, INTRANASAL; ANIMALS; BACTERIAL CAPSULES; COLONY COUNT, MICROBIAL; DISEASE SUSCEPTIBILITY; HUMANS; IMMUNITY, INNATE; INJECTIONS, INTRAVENOUS; MALE; MICE; MICE, INBRED C57BL; PNEUMOCOCCAL INFECTIONS; SEPSIS; SPLEEN; SPLENECTOMY; STREPTOCOCCUS PNEUMONIAE; SURVIVAL RATE;

EID: 79959524844     PISSN: 01712985     EISSN: 18783279     Source Type: Journal    
DOI: 10.1016/j.imbio.2011.02.004     Document Type: Article

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