An efficient synthesis for a new class antimalarial agent, 7-(2-carboxyethyl)-1,3-dihydro-1-hydroxy-2,1-benzoxaborole

Tetrahedron Letters

Volumn 52, Issue 30, 2011, Pages 3909-3911

  Zhang, Yong Kang ^a   Plattner, Jacob J ^a   Easom, Eric E ^a   Waterson, David ^b   Ge, Min ^c   Li, Zhiya ^c   Li, Lingchao ^c   Jian, Yong ^c  

^a PFIZER INC   (United States)

^b International Center Cointrin   (Switzerland)

^c Acesys Pharmatech Inc   (China)

Author keywords

Antimalarial therapeutics; Benzoxaborole; Malaria; Plasmodium falciparum; Synthesis

Indexed keywords

7 (2 CARBOXYETHYL) 1,3 DIHYDRO 1 HYDROXY 2,1 BENZOXABOROLE; ANTIMALARIAL AGENT; UNCLASSIFIED DRUG;

ARTICLE; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; IC 50; MALARIA FALCIPARUM; PLASMODIUM FALCIPARUM;

PLASMODIUM FALCIPARUM;

EID: 79959522795     PISSN: 00404039     EISSN: 18733581     Source Type: Journal    
DOI: 10.1016/j.tetlet.2011.05.088     Document Type: Article

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