Ursodeoxycholic acid for treatment of fatty liver disease and dyslipidemia in morbidly obese patients

Digestive Diseases

Volumn 29, Issue 1, 2011, Pages 117-118

  Marschall, Hanns Ulrich ^a,b,f   Wagner, Martin ^d   Zollner, Gernot ^d   Fickert, Peter ^d   Lackner, Caroline ^e   Thorell, Anders ^c   Trauner, Michael ^d  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c ERSTA HOSPITAL   (Sweden)

^d MEDICAL UNIVERSITY OF VIENNA   (Austria)

^e MEDICAL UNIVERSITY OF GRAZ   (Austria)

^f UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

Bariatric surgery; Glucose tolerance; Insulin resistance

Indexed keywords

BILE ACID; G PROTEIN COUPLED RECEPTOR; URSODEOXYCHOLIC ACID;

ADULT; BARIATRIC SURGERY; BODY MASS; CLINICAL ARTICLE; CONFERENCE PAPER; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; DRUG RECEPTOR BINDING; DYSLIPIDEMIA; FATTY LIVER; FEMALE; FOLLOW UP; GLUCOSE TOLERANCE; HUMAN; INSULIN SENSITIVITY; LIVER FUNCTION TEST; MALE; MORBID OBESITY; NONALCOHOLIC FATTY LIVER; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

ADULT; DYSLIPIDEMIAS; FATTY LIVER; FEMALE; GLUCOSE TOLERANCE TEST; HUMANS; INSULIN RESISTANCE; MALE; OBESITY, MORBID; URSODEOXYCHOLIC ACID;

EID: 79959512975     PISSN: 02572753     EISSN: 14219875     Source Type: Journal    
DOI: 10.1159/000324146     Document Type: Conference Paper

References (8)

1. Angulo P: Nonalcoholic fatty liver disease. N Engl J Med 2002; 346: 1221-1231.
2. Sjostrom L, Narbro K, Sjostrom CD, et al: Effects of bariatric surgery on mortality in Swedish obese subjects. N Engl J Med 2007; 357:741-752. (Pubitemid 47295641)
3. Houten SM, Watanabe M, Auwerx J: Endocrine functions of bile acids. EMBO J 2006; 25:1419-1425.
4. Ozcan U, Yilmaz E, Ozcan L, et al: Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes. Science 2006; 313:1137-1140. (Pubitemid 44300242)
5. Kars M, Yang L, Gregor MF, et al: Taurour-sodeoxycholic acid may improve liver and muscle but not adipose tissue insulin sensitivity in obese men and women. Diabetes 2010; 59: 1899-1905.
6. European Association for the Study of the Liver: EASL Clinical Practice Guidelines: management of cholestatic liver diseases. J Hepatol 2009; 51: 237-267.
7. Lindor KD, Kowdley KV, Heathcote EJ, et al: Ursodeoxycholic acid for treatment of nonalcoholic steatohepatitis: results of a randomized trial. Hepatology 2004; 39: 770-778. (Pubitemid 38337657)
8. Leuschner UF, Lindenthal B, Herrmann G, et al: High-dose ursodeoxycholic acid therapy for nonalcoholic steatohepatitis: a double-blind, randomized, placebo-controlled trial. Hepatology 2010; 52: 472-479.