The interaction between Candida krusei and murine macrophages results in multiple outcomes, including intracellular survival and escape from killing

Infection and Immunity

Volumn 79, Issue 6, 2011, Pages 2136-2144

  García Rodas, Rocío ^a   González Camacho, Fernando ^a   Rodríguez Tudela, Juan Luis ^a   Cuenca Estrella, Manuel ^a   Zaragoza, Oscar ^a  

^a INSTITUTO DE SALUD CARLOS III   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; FLUORESCENT DYE; INTERLEUKIN 6; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA;

ACTIN POLYMERIZATION; ANIMAL CELL; ARTICLE; CANDIDA KRUSEI; CANDIDIASIS; CELL DIVISION; CELL FUSION; CHEMOTAXIS; CYTOKINE PRODUCTION; FUNGUS HYPHAE; MACROPHAGE; MALE; NONHUMAN; PERITONEUM MACROPHAGE; PHAGOCYTOSIS; PHAGOLYSOSOME; PRIORITY JOURNAL; YEAST CELL;

ANIMALS; CANDIDA; CANDIDIASIS; CELL LINE; FLUORESCENT ANTIBODY TECHNIQUE; HOST-PATHOGEN INTERACTIONS; INTERLEUKIN-6; MACROPHAGES; MICE; PHAGOCYTOSIS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 79959480893     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00044-11     Document Type: Article

References (35)

1. Alvarez, M., and A. Casadevall. 2007. Cell-to-cell spread and massive vacuole formation after Cryptococcus neoformans infection of murine macrophages. BMC Immunol. 8:16.
2. Alvarez, M., and A. Casadevall. 2006. Phagosome extrusion and host-cell survival after Cryptococcus neoformans phagocytosis by macrophages. Curr. Biol. 16:2161-2165.
3. Bliska, J. B., and A. Casadevall. 2009. Intracellular pathogenic bacteria and fungi-a case of convergent evolution? Nat. Rev. Microbiol. 7:165-171.
4. Casadevall, A., and L. A. Pirofski. 2003. The damage-response framework of microbial pathogenesis. Nat. Rev. Microbiol. 1:17-24.
5. Charlier, C., et al. 2009. Evidence for a role of monocytes in dissemination and brain invasion by Cryptococcus neoformans. Infect. Immun. 77:120-127.
6. Drevets, D. A., et al. 2004. The Ly-6Chigh monocyte subpopulation transports Listeria monocytogenes into the brain during systemic infection of mice. J. Immunol. 172:4418-4424.
7. Eissenberg, L. G., W. E. Goldman, and P. H. Schlesinger. 1993. Histoplasma capsulatum modulates the acidification of phagolysosomes. J. Exp. Med. 177:1605-1611.
8. Fernandez-Arenas, E., et al. 2009. Candida albicans actively modulates intracellular membrane trafficking in mouse macrophage phagosomes. Cell. Microbiol. 11:560-589.
9. Reference deleted.
10. Horn, D. L., et al. 2009. Epidemiology and outcomes of candidemia in 2019 patients: data from the prospective antifungal therapy alliance registry. Clin. Infect. Dis. 48:1695-1703.
11. Kurtzman, C. P., and J. W. Fell (ed.). 1997. The yeasts: a taxonomical study. Elsevier, Amsterdam, Netherlands.
12. Lewis, R. E. 2009. Overview of the changing epidemiology of candidemia. Curr. Med. Res. Opin. 25:1732-1740.
13. Luo, Y., M. Alvarez, L. Xia, and A. Casadevall. 2008. The outcome of phagocytic cell division with infectious cargo depends on single phagosome formation. PLoS One 3:e3219.
14. Luo, Y., S. C. Tucker, and A. Casadevall. 2005. Fc- and complement-receptor activation stimulates cell cycle progression of macrophage cells from G1 to S. J. Immunol. 174:7226-7233.
15. Ma, H., J. E. Croudace, D. A. Lammas, and R. C. May. 2007. Direct cellto-cell spread of a pathogenic yeast. BMC Immunol. 8:15.
16. Ma, H., J. E. Croudace, D. A. Lammas, and R. C. May. 2006. Expulsion of live pathogenic yeast by macrophages. Curr. Biol. 16:2156-2160.
17. Marcil, A., et al. 2008. Analysis of PRA1 and its relationship to Candida albicans-macrophage interactions. Infect. Immun. 76:4345-4358.
18. Maxson, M. E., E. Dadachova, A. Casadevall, and O. Zaragoza. 2007. Radial mass density, charge, and epitope distribution in the Cryptococcus neoformans capsule. Eukaryot. Cell 6:95-109.
19. Merz, W. G., J. E. Karp, D. Schron, and R. Saral. 1986. Increased incidence of fungemia caused by Candida krusei. J. Clin. Microbiol. 24:581-584.
20. Nguyen, L., and J. Pieters. 2005. The Trojan horse: survival tactics of pathogenic mycobacteria in macrophages. Trends Cell Biol. 15:269-276.
21. Peluso, R., A. Haase, L. Stowring, M. Edwards, and P. Ventura. 1985. A Trojan horse mechanism for the spread of visna virus in monocytes. Virology 147:231-236.
22. Pfaller, M. A., et al. 2008. Candida krusei, a multidrug-resistant opportunistic fungal pathogen: geographic and temporal trends from the ARTEMIS DISK Antifungal Surveillance Program, 2001 to 2005. J. Clin. Microbiol. 46:515-521.
23. Raschke, W. C., S. Baird, P. Ralph, and I. Nakoinz. 1978. Functional macrophage cell lines transformed by Abelson leukemia virus. Cell 15:261-267.
24. Russel, D. G., and S. Gordon. 2009. Phagocyte-pathogen interaction: macrophages and the host response to infection, 1st ed. ASM Press, Washington, DC.
25. Samaranayake, Y. H., and L. P. Samaranayake. 1994. Candida krusei: biology, epidemiology, pathogenicity and clinical manifestations of an emerging pathogen. J. Med. Microbiol. 41:295-310.
26. Samaranayake, Y. H., P. C. Wu, L. P. Samaranayake, and P. L. Ho. 1998. The relative pathogenicity of Candida krusei and C. albicans in the rat oral mucosa. J. Med. Microbiol. 47:1047-1057.
27. Samaranayake, Y. H., P. C. Wu, L. P. Samaranayake, M. So, and K. Y. Yuen. 1994. Adhesion and colonisation of Candida krusei on host surfaces. J. Med. Microbiol. 41:250-258.
28. Shao, X., et al. 2005. An innate immune system cell is a major determinant of species-related susceptibility differences to fungal pneumonia. J. Immunol. 175:3244-3251.
29. Strasser, J. E., et al. 1999. Regulation of the macrophage vacuolar ATPase and phagosome-lysosome fusion by Histoplasma capsulatum. J. Immunol. 162:6148-6154.
30. Tucker, S. C., and A. Casadevall. 2002. Replication of Cryptococcus neoformans in macrophages is accompanied by phagosomal permeabilization and accumulation of vesicles containing polysaccharide in the cytoplasm. Proc. Natl. Acad. Sci. U. S. A. 99:3165-3170.
31. Voelz, K., D. A. Lammas, and R. C. May. 2009. Cytokine signalling regulates the outcome of intracellular macrophage parasitism by Cryptococcus neoformans. Infect. Immun. 77:3450-3457.
32. Zaragoza, O., M. Alvarez, A. Telzak, J. Rivera, and A. Casadevall. 2007. The relative susceptibility of mouse strains to pulmonary Cryptococcus neoformans infection is associated with pleiotropic differences in the immune response. Infect. Immun. 75:2729-2739.
33. Zaragoza, O., et al. 2008. Capsule enlargement in Cryptococcus neoformans confers resistance to oxidative stress suggesting a mechanism for intracellular survival. Cell. Microbiol. 10:2043-2057.
34. Zaragoza, O., C. P. Taborda, and A. Casadevall. 2003. The efficacy of complement-mediated phagocytosis of Cryptococcus neoformans is dependent on the location of C3 in the polysaccharide capsule and involves both direct and indirect C3-mediated interactions. Eur. J. Immunol. 33:1957-1967.
35. Zhao, X. R., and C. C. Villar. 2011. Trafficking of Candida albicans through oral epithelial endocytic compartments. Med. Mycol. 49:212-217.