Highly sensitive determination and validation of gabapentin in pharmaceutical preparations by HPLC with 4-Fluoro-7-Nitrobenzofurazan derivatization and fluorescence detection

Journal of Chromatographic Science

Volumn 49, Issue 6, 2011, Pages 417-421

  Ulu, Sevgi Tatar ^a   Kel, Elif ^a  

^a ISTANBUL UNIVERSITY   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 79959465317     PISSN: 00219665     EISSN: None     Source Type: Journal    
DOI: 10.1093/chrsci/49.6.417     Document Type: Article

References (36)

1. K.L. Goa and E.M. Sorkin. Gabapentin. Drugs 46: 409-427 (1993).
2. N.B. Finnerup, H. Gottrup, and T.S. Jensen. Anticonvulsants in central pain. Expert Opin. Pharmacother. 3: 1411-1420 (2002). (Pubitemid 35174873)
3. J.K. Baillie and I. Power. The mechanism of action of gabapentin in neuropathic pain Curr. Opin. Investig. Drugs 7: 33-39 (2006). (Pubitemid 43115778)
4. G.J. Sills. The mechanisms of action of gabapentin and pregabalin. Curr. Opin. Pharmacol. 6: 108-113 (2006). (Pubitemid 43103827)
5. O.A. Petroff, D.L. Rothmann, K.L. Behar, and R.H. Mattson. The effect of gabapentin on brain gamma-aminobutyric acid in patients with epilepsy. Ann. Neurol. 39: 95-99 (1996). (Pubitemid 26052222)
6. C.E. Wolf, J.J. Saady, and A. Polkis. Determination of gabapentin in serum using solid-phase extraction and gas-liquid chromatography. J. Anal. Toxicol. 20: 498-501 (1996). (Pubitemid 26327473)
7. W.D. Hooper, M.C. Kavanagh, and R.G. Dickinson. Determination of gabapentin plasma and urine by capillary column gas chromatography. J. Chromatogr. 529: 167-174 (1990). (Pubitemid 20221160)
8. M.M. Kushnir, J. Crossett, P.I. Brown, and F.M. Urry. Analysis of gabapentin in serum and plasma by solid-phase extraction and gas chromatography-mass spectrometry for therapeutic drug monitoring. J. Anal. Toxicol. 23: 1-6 (1999). (Pubitemid 29327445)
9. D.C. Borrey, K.O. Godderis, V.I. Engelrelst, D.R. Bernard, and M.R. Langlois. Quantitative determination of vigabatrin and gabapentin in human serum by gas chromatography-mass spectrometry. Clin. Chim. Acta 354: 147-151(2005). (Pubitemid 40320685)
10. C. Gambelunghe, G. Mariucci, M. Tantucci, and M.V. Ambrosini. Gas chromatography-tandem mass spectrometry analysis of gabapentin in serum. Biomed. Chromatogr. 19: 63-67 (2004).
11. Z. Zhu and L. Neirinck. High-performance liquid chromatographic method for the determination of gabapentin in human plasma. J. Chromatogr. B 779: 307-312 (2002). (Pubitemid 35279457)
12. H. Jalalizadeh, E. Souri, M.B. Tehrani, and A. Jahangiri. Validated HPLC method for the determination of gabapentin in human plasma using pre-column derivatization with 1-fluoro-2,4-dinitrobenzene and its application to a pharmacokinetic study. J. Chromatogr. B 854: 43-47 (2007). (Pubitemid 46962358)
13. T.A. Vermeij and P.M. Edelbroek. Simultaneous high-performance liquid chromatographic analysis of pregabalin, gabapentin and vigabatrin in human serum by precolumn derivatization with ophtaldialdehyde and fluorescence detection. J. Chromatogr. B 810: 297-303 (2004). (Pubitemid 39243318)
14. H. Hengy and E.U. Kolle. Determination of gabapentin in plasma and urine by high-performance liquid chromatography and precolumn labelling for ultraviolet detection. J. Chromatogr. 341: 473-478 (1985). (Pubitemid 15013697)
15. D. Gauthier and R. Gupta. Determination of gabapentin in plasma by liquid chromatography with fluorescence detection after solidphase extraction with a C18 column. Clin. Chem. 48: 2259-2261 (2002). (Pubitemid 35397574)
16. G. Forrest, G.J. Sills, J.P. Leach, M.J. Brodie. Determination of gabapentin in plasma by high-performance liquid chromatography. J. Chromatogr. B 681: 421-425 (1996). (Pubitemid 26191840)
17. U.H. Juergens, T.W. May, and B. Rambeck. Simultaneous HPLC determination of vigabatrin and gabapentin in serum with automated pre-injection derivation. Liq. Chromatogr Rel. Tech. 19: 1459-1471 (1996). (Pubitemid 26168961)
18. N. Wad and G. Krämer. Sensitive high-performance liquid chromatographic method with fluorometric detection for the simultaneous determination of gabapentin and vigabatrin in serum and urine. J. Chromatogr. 705: 154-158 (1998). (Pubitemid 28045669)
19. P.H. Tang, M.V. Miles, T.A. Glauser, and T. DeGrauw. Automated microanalysis of gabapentin in human serum by high-performance liquid chromatography with fluorometric detection. J. Chromatogr. B 727: 125-129 (1999). (Pubitemid 29189284)
20. G. Bahrami and A. Kiani. Sensitive high-performance liquid chromatographic quantitation of gabapentin in human serum using liquid-liquid extraction and pre-column derivatization with 9-fluorenylmethyl chloroformate. J. Chromatogr. B 835: 123-126 (2006).
21. J. Qibo and L. Shuguang. Rapid high-performance liquid chromatographic determination of serum gabapentin. J. Chromatogr. B 727: 119-123 (1999).
22. F. Daniel, L.G. Chollet, and J.G.A. Corinne. Fast isocratic high-performance liquid chromatographic assay method for the simultaneous determination of gabapentin and vigabatrin in human serum. J. Chromatogr. B 746: 311-314 (2000).
23. P. Krivanek, K. Koppatz, and K. Turnheim. Simultaneous isocratic HPLC determination of vigabatrin and gabapentin in human plasma by dansyl derivatization. Ther. Drug. Monit. 25: 374-377 (2003). (Pubitemid 36638184)
24. D.R. Ifa, M. Falci, M.E. Moreas, F.A. Berreza, and M.O. Moraes. Gabapentin quantification in human plasma by high-performance liquid chromatography coupled to electrospray tandem mass spectrometry. Application to bioequivalence study. J. Mass Spectrom. 36: 188-194 (2001). (Pubitemid 32186236)
25. A. Ojha, R. Rathod, C. Patel, and H. Padh. LC-MS determination of gabapentin from human plasma. Chromatographia 66: 853-857 (2007). (Pubitemid 350211963)
26. N.V. Ramakrishna, K.N. Vishwottam, M. Koteshwara, S. Manoj, M. Santosh, J. Chidambara, B. Sumatha, and D.P. Varma. Rapid quantification of gabapentin in human plasma by liquid chromatography/ tandem mass spectrometry. J. Pharm. Biomed. Anal. 40: 360-368 (2006). (Pubitemid 43143340)
27. K.C. Carlsson and J.L.E. Reubsaet. Sample preparation and determination of gabapentin in venous and capillary blood using liquid chromatography-tandem mass spectrometry. J. Pharm. Biomed. Anal. 434: 415-423 (2004). (Pubitemid 38167772)
28. S.Y. Chang, F.Y. Wang. Determination of gabapentin in human plasma by capillary electrophoresis with laser-induced fluorescence detection and acetonitrile stacking technique. J. Chromatogr. B: Biomed. Appl. 799: 265-270 (2004). (Pubitemid 37510229)
29. S.T. Ulu and E. Kel. Sensitive spectrofluorimetric method of analysis for gabapentin in pure and pharmaceutical preparations. Chin. J. Chem. 29: 562-566 (2011).
30. M.M. Ayad, M.M. El-Henawee, H.E. Abdellatef, and H.M. El-Sayed. Spectrophotometric and spectrofluorimetric determination of gabapentin and cefprozil monohydrate using acetylacetone and formaldehyde. J. Pharm. Sci. 19: 157-160 (2005).
31. M.F.T. Ribeiro, J.L.M. Santos, and J.L.F. Lima. Piezoelectric pumping in flow analysis: Application to the spectrophotometric determination of gabapentin. Anal. Chim. Acta. 26: 14-20 (2007). (Pubitemid 47445410)
32. R. Sekar and S. Azhaguvel. Indirect photometric assay determination of gabapentin in bulk drug and capsules by capillary electrophoresis. J. Pharm. Biomed. Anal. 36: 663-667 (2004). (Pubitemid 39441342)
33. E. Souri, H. Jalalizadeh, and A. Shafiee. Optimization of an HPLC method for determination of gabapentin in dosage forms through derivatization with 1-fluoro-2,4-dinitrobenzene. Chem. Pharm. Bull. 55: 1427-1430 (2007). (Pubitemid 350022020)
34. K. Imai, S. Uzu, and T. Toyoóka. Availability of fluorogenic reagents having a benzofurazan structure in the biosciences. Anal. Chim. Acta 290: 3-20 (1994). (Pubitemid 24174678)
35. ICH (1996) Validation of analytical procedures: methodology. ICH harmonised tripartite guideline, having reached step 4 of the ICH process at the ICH steering committee meeting on 6 November 1996.
36. United States Pharmacopeial Convention (2009) United States Pharmacopeia 32 (USP 32), pp 2462-2465.