Spatial correlations of trabecular bone microdamage with local stresses and strains using rigid image registration

Journal of Biomechanical Engineering

Volumn 133, Issue 6, 2011, Pages

  Nagaraja, Srinidhi ^a,b   Skrinjar, Oskar ^b   Guldberg, Robert E ^a,b  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^b GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

finite element analysis; image registration; microcomputed tomography; microdamage; trabecular bone

Indexed keywords

BONE STRUCTURE; FINITE ELEMENT MODELS; GRID REFINEMENT; GRID SIZE; HISTOLOGICAL SECTION; IMAGE REGISTRATION ALGORITHM; LOCAL CORRELATIONS; LOCAL STRAINS; LOCAL STRESS; MICRO COMPUTED TOMOGRAPHY (MICRO-CT); MICRO CT; MICRO-DAMAGE; MICRO-STRUCTURAL; MICROCOMPUTED TOMOGRAPHY; PIXEL LEVEL; REGISTRATION TECHNIQUES; RIGID REGISTRATION; SPATIAL CORRELATIONS; SPATIAL GRIDS; TRABECULAR BONE MICRODAMAGE; TRABECULAR BONES;

ALGORITHMS; BONE; ELASTICITY; FINITE ELEMENT METHOD; IMAGE REGISTRATION; MAMMALS; PIXELS; STRUCTURAL DESIGN; TISSUE; TOMOGRAPHY;

COMPUTERIZED TOMOGRAPHY;

ACCURACY; ALGORITHM; ANIMAL EXPERIMENT; ARTICLE; BONE INJURY; BONE STRUCTURE; COW; FINITE ELEMENT ANALYSIS; HISTOLOGY; IMAGE ANALYSIS; IMAGE QUALITY; IMAGE RECONSTRUCTION; MICRO-COMPUTED TOMOGRAPHY; NONHUMAN; STRESS STRAIN RELATIONSHIP; TRABECULAR BONE; ANIMAL; BIOMECHANICS; BIOMEDICAL ENGINEERING; BONE; CATTLE; IMAGE PROCESSING; IN VITRO STUDY; INJURY; MECHANICAL STRESS; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY; RADIOGRAPHY;

FLUORESCENT DYE;

ALGORITHMS; ANIMALS; BIOMECHANICS; BIOMEDICAL ENGINEERING; BONE AND BONES; CATTLE; FINITE ELEMENT ANALYSIS; FLUORESCENT DYES; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; STRESS, MECHANICAL; X-RAY MICROTOMOGRAPHY;

EID: 79959416819     PISSN: 01480731     EISSN: 15288951     Source Type: Journal    
DOI: 10.1115/1.4004164     Document Type: Article

References (13)

1. AAOS. Osteoporosis and Bone Health. In: Burden of Musculoskeletal Diseases in the United States: Prevalence, Societal and Economic Cost. 1st ed: American Academy of Orthopaedic Surgeons; 2008, pp. 97-121.
2. Keaveny, T. M., Morgan, E. F., Niebur, G. I., and Yeh, O. C., 2001, "Biomechanics of Trabecular Bone," Annu. Rev. Biomed. Eng., 3, pp. 307-333. (Pubitemid 32928042)
3. Van Rietbergen, B., Weinans, H., and Huiskes, R., 1996, "Computational Strategies for Iterative Solutions of Large FEM Applications Employing Voxel Data," Int. J. Numer. Methods Eng., 39, pp. 2743-2767. (Pubitemid 126648046)
4. Lee, T. C., Mohsin, S., Taylor, D., Parkesh, R., Gunnlaugsson, T., O'Brien, F. J., Giehl, M., and Gowin, W., 2003, "Detecting Microdamage in Bone," J. Anat., 203, pp. 161-172. (Pubitemid 36974661)
5. Lynch, J. A., Grigoryan, M., Fierlinger, A., Guermazi, A., Zaim, S., MacLean, D. B., and Genant, H. K., 2004, "Measurement of Changes in Trabecular Bone at Fracture Sites Using X-Ray CT and Automated Image Registration and Processing," J. Orthop. Res., 22, pp. 362-367. (Pubitemid 38155293)
6. Newitt, D. C., van Rietbergen, B., and Majumdar, S., 2002, "Processing and Analysis of In Vivo High-Resolution MR Images of Trabecular Bone for Longitudinal Studies: Reproducibility of Structural Measures and Micro-Finite Element Analysis Derived Mechanical Properties," Osteoporosis Int., 13, pp. 278-287. (Pubitemid 34506736)
7. Waarsing, J. H., Day, J. S., van der Linden, J. C., Ederveen, A. G., Spanjers, C., De Clerck, N., Sasov, A., Verhaar, J. A., and Weinans, H., 2004, "Detecting and Tracking Local Changes in the Tibiae of Individual Rats: A Novel Method to Analyse Longitudinal In Vivo Micro-CT Data," Bone, 34, pp. 163-169. (Pubitemid 38142445)
8. Nagaraja, S., Lin, A. S., and Guldberg, R. E., 2007, "Age-Related Changes in Trabecular Bone Microdamage Initiation," Bone, 40, pp. 973-980. (Pubitemid 46386534)
9. Keaveny, T. M., Wachtel, E. F., Ford, C. M., and Hayes, W. C., 1994, "Differences Between the Tensile and Compressive Strengths of Bovine Tibial Trabecular Bone Depend on Modulus," J. Biomech., 27, pp. 1137-1146. (Pubitemid 24211194)
10. Lee, T. C., Arthur, T. L., Gibson, L. J., and Hayes, W. C., 2000, "Sequential Labelling of Microdamage in Bone Using Chelating Agents," J. Orthop. Res., 18, pp. 322-325. (Pubitemid 30304763)
11. O'Brien, F. J., Taylor, D., and Lee, T. C., 2002, "An Improved Labelling Technique for Monitoring Microcrack Growth in Compact Bone," J. Biomech., 35, pp. 523-526. (Pubitemid 34273645)
12. Van Rietbergen, B., Weinans, H., Huiskes, R., and A. Odgaard, A., 1995, "A New Method to Determine Trabecular Bone Elastic Properties and Loading Using Micromechanical Finite-Element Models," J. Biomech., 28, pp. 69-81. (Pubitemid 24343733)
13. McNamara, L. M., Van der Linden, J. C., Weinans, H., and Prendergast, P. J., 2006, "Stress-Concentrating Effect of Resorption Lacunae in Trabecular Bone," J. Biomech., 39, pp. 734-741. (Pubitemid 43139000)