Severe relapse of multiple sclerosis during plasma exchange treatment

Multiple Sclerosis Journal

Volumn 17, Issue 6, 2011, Pages 759-762

  Matzke, Burkhard ^a,b   Metze, Christoph ^a   Winkelmann, Alexander ^a,d   Grossmann, Annette ^a   Hartung, Hans Peter ^c   Benecke, Reiner ^a   Zettl, Uwe Klaus ^a  

^a UNIVERSITY OF ROSTOCK   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c HEINRICH HEINE UNIVERSITY   (Germany)

^d Klinik und Poliklinik fuer Neurologie Universitaetsmedizin Rostock   (Germany)

Author keywords

disease modifying therapies; immunology; multiple sclerosis

Indexed keywords

BETA1A INTERFERON; INTERFERON BETA SERINE; METHYLPREDNISOLONE; NATALIZUMAB;

ADULT; ARTICLE; CASE REPORT; DISEASE SEVERITY; DRUG DOSE ESCALATION; DRUG MEGADOSE; EXPANDED DISABILITY STATUS SCALE; FEMALE; HUMAN; LONG TERM CARE; MULTIPLE SCLEROSIS; NEUROLOGIC DISEASE; NUCLEAR MAGNETIC RESONANCE IMAGING; PLASMAPHERESIS; RELAPSE; RELAPSING REMITTING MULTIPLE SCLEROSIS; STEROID THERAPY; TREATMENT FAILURE; TREATMENT RESPONSE;

EID: 79959413897     PISSN: 13524585     EISSN: 14770970     Source Type: Journal    
DOI: 10.1177/1352458511401461     Document Type: Article

References (11)

1. Lucchinetti C, Brück W, Parisi J, Scheithauer B, Rodriguez M, Lassmann H. Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination. Ann Neurol. 2000 ; 47: 707-717 (Pubitemid 30390191)
2. Barnett MH, Prineas JW. Relapsing and remitting multiple sclerosis: pathology of the newly forming lesion. Ann Neurol. 2004 ; 55: 458-468 (Pubitemid 38391962)
3. Breij EC, Brink BP, Veerhuis R, van den Berg C, Vloet R, Yan R, et al. Homogeneity of active demyelinating lesions in established multiple sclerosis. Ann Neurol. 2008 ; 63: 16-25 (Pubitemid 351240547)
4. Lassmann H, Brück W, Lucchinetti CF. The immunopathology of multiple sclerosis: an overview. Brain Pathol. 2007 ; 17: 210-218 (Pubitemid 46466140)
5. Keegan M, König F, McClelland R, Brück W, Morales Y, Bitsch A, et al. Relation between humoral pathological changes in multiple sclerosis and response to therapeutic plasma exchange. Lancet. 2005 ; 366: 579-582 (Pubitemid 41140333)
6. Weinshenker BG, O'Brien PC, Petterson TM, Noseworthy JH, Lucchinetti CF, Dodick DW, et al. A randomized trial of plasma exchange in acute central nervous system inflammatory demyelinating disease. Ann Neurol. 1999 ; 46: 878-886
7. Wiendl H, Toyka KV, Rieckmann P, Gold R, Hartung HP, et al. Basic and escalating immunomodulatory treatments in multiple sclerosis: current therapeutic recommendations. J Neurol. 2008 ; 255: 1449-1463
8. Wirguin I, Shinar E, Abramsky O. Relapse of multiple sclerosis following acute allergic reactions to plasma during plasmapheresis. J Neurol. 1989 ; 236: 62-63 (Pubitemid 19113129)
9. Muchnik S, Jáuregui WO, Mazía C. Acute and reversible worsening of multiple sclerosis treated with plasmapheresis. A form of Uhthoff symptom?. Medicina (B Aires). 1985 ; 45: 207-208
10. Barnett MH, Henderson AP, Prineas JW. The macrophage in MS: just a scavenger after all? Pathology and pathogenesis of the acute MS lesion. Mult Scler. 2006 ; 12: 121-132
11. Schmidt J, Gold R, Schönrock L, Zettl UK, Hartung HP, Toyka KV. T-cell apoptosis in situ in experimental autoimmune encephalomyelitis following methylprednisolone pulse therapy. Brain. 2000 ; 123: 1431-1441 (Pubitemid 30420943)