ER stress inducer, thapsigargin, decreases extracellular-superoxide dismutase through MEK/ERK signalling cascades in COS7 cells

Free Radical Research

Volumn 45, Issue 6, 2011, Pages 692-698

  Kamiya, Tetsuro ^a,b   Obara, Aya ^a   Hara, Hirokazu ^a   Inagaki, Naoki ^b   Adachi, Tetsuo ^a  

^a GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

^b GIFU UNIVERSITY   (Japan)

Author keywords

chronic kidney disease; endoplasmic reticulum stress; extracellular signal regulated kinase; Extracellular superoxide dismutase; thapsigargin

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; COPPER ZINC SUPEROXIDE DISMUTASE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; MANGANESE SUPEROXIDE DISMUTASE; MITOGEN ACTIVATED PROTEIN KINASE; REACTIVE OXYGEN METABOLITE; THAPSIGARGIN; TUNICAMYCIN;

ARTICLE; CELL DAMAGE; CELL STRAIN COS7; CELL VIABILITY; CHRONIC KIDNEY DISEASE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; HYPOXIA; OUTCOME ASSESSMENT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; CELL HYPOXIA; CERCOPITHECUS AETHIOPS; COS CELLS; ENDOPLASMIC RETICULUM; HEAT-SHOCK PROTEINS; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASES; STRESS, PHYSIOLOGICAL; SUPEROXIDE DISMUTASE; THAPSIGARGIN; TRANSCRIPTION FACTOR CHOP; TRANSCRIPTION, GENETIC; TUNICAMYCIN;

EID: 79959407955     PISSN: 10715762     EISSN: 10292470     Source Type: Journal    
DOI: 10.3109/10715762.2011.567985     Document Type: Article

References (32)

1. Vachier I, Chanez P, Le Doucen C, Damon M, Descomps B, Godard P. Enhancement of reactive oxygen species formation in stable and unstable asthmatic patients. Eur Respir J 1994; 7:1585-1592. (Pubitemid 24294241)
2. Wright E, Jr, Scism-Bacon JL, Glass LC. Oxidative stress in type 2 diabetes: the role of fasting and postprandial glycaemia. Int J Clin Pract 2006;60:308-314. (Pubitemid 43337611)
3. Amstad P, Cerutti P. Genetic modulation of the cellular antioxidant defense capacity. Environ Health Perspect 1990; 88:77-82. (Pubitemid 20352951)
4. Cerutti P, Ghosh R, Oya Y, Amstad P. The role of the cellular antioxidant defense in oxidant carcinogenesis. Environ Health Perspect 1994;102:123-129.
5. Folz RJ, Crapo JD. Extracellular superoxide dismutase (SOD3): tissue-specifi c expression, genomic characterization, and computer-assisted sequence analysis of the human EC SOD gene. Genomics 1994;22:162-171. (Pubitemid 24234100)
6. Ookawara T, Imazeki N, Matsubara O, Kizaki T, Oh-Ishi S, Nakao C, Sato Y, Ohno H. Tissue distribution of immunoreactive mouse extracellular superoxide dismutase. Am J Physiol 1998;275:C840-C847.
7. Marklund SL. Human copper-containing superoxide dismutase of high molecular weight. Proc Natl Acad Sci USA 1982;79:7634-7638. (Pubitemid 13173159)
8. Kimura K, Jin H, Ogawa M, Aoe T. Dysfunction of the ER chaperone BiP accelerates the renal tubular injury. Biochem Biophys Res Commun 2008;366:1048-1053.
9. Bohle A, Wehrmann M, Bogenschutz O, Batz C, Vogl W, Schmitt H, Muller CA, Muller GA. The long-term prognosis of the primary glomerulonephritides. A morphological and clinical analysis of 1747 cases. Pathol Res Pract 1992;188: 908-924.
10. Lee PJ, Jiang BH, Chin BY, Iyer NV, Alam J, Semenza GL, Choi AM. Hypoxia-inducible factor-1 mediates transcriptional activation of the heme oxygenase-1 gene in response to hypoxia. J Biol Chem 1997;272:5375-5381. (Pubitemid 27102353)
11. Levy AP, Levy NS, Wegner S, Goldberg MA. Transcriptional regulation of the rat vascular endothelial growth factor gene by hypoxia. J Biol Chem 1995;270:13333-13340.
12. Schuster SJ, Badiavas EV, Costa-Giomi P, Weinmann R, Erslev AJ, Caro J. Stimulation of erythropoietin gene transcription during hypoxia and cobalt exposure. Blood 1989;73:13-16. (Pubitemid 19040947)
13. Kuznetsov G, Bush KT, Zhang PL, Nigam SK. Perturbations in maturation of secretory proteins and their association with endoplasmic reticulum chaperones in a cell culture model for epithelial ischemia. Proc Natl Acad Sci USA 1996;93: 8584-8589. (Pubitemid 26269603)
14. Mori K. Tripartite management of unfolded proteins in the endoplasmic reticulum. Cell 2000;101:451-454.
15. Kamiya T, Hara H, Yamada H, Imai H, Inagaki N, Adachi T. Cobalt chloride decreases EC-SOD expression through intracellular ROS generation and p38-MAPK pathways in COS7 cells. Free Radic Res 2008;42:949-956.
16. Adachi T, Hara H, Yamada H, Yamazaki N, Yamamoto M, Sugiyama T, Futenma A, Katagiri Y. Heparin-stimulated expression of extracellular-superoxide dismutase in human fibroblasts. Atherosclerosis 2001;159:307-312. (Pubitemid 33127244)
17. Adachi T, Ohta H, Yamada H, Futenma A, Kato K, Hirano K. Quantitative analysis of extracellular-superoxide dismutase in serum and urine by ELISA with monoclonal antibody. Clin Chim Acta 1992;212:89-102.
18. Liang SH, Zhang W, McGrath BC, Zhang P, Cavener DR. PERK (eIF2 kinase) is required to activate the stressactivated MAPKs and induce the expression of immediateearly genes upon disruption of ER calcium homoeostasis. Biochem J 2006;393:201-209. (Pubitemid 43049316)
19. Hung JH, Su IJ, Lei HY, Wang HC, Lin WC, Chang WT, Huang W, Chang WC, Chang YS, Chen CC, Lai MD. Endoplasmic reticulum stress stimulates the expression of cyclooxygenase-2 through activation of NF-B and pp38 mitogen-activated protein kinase. J Biol Chem 2004;279: 46384-46392. (Pubitemid 39518279)
20. Denys A, Aires V, Hichami A, Khan NA. Thapsigarginstimulated MAP kinase phosphorylation via CRAC channels and PLD activation: inhibitory action of docosahexaenoic acid. FEBS Lett 2004;564:177-182. (Pubitemid 38490721)
21. Kamiya T, Hara H, Inagaki N, Adachi T. The effect of hypoxia mimetic cobalt chloride on the expression of EC-SOD in 3T3-L1 adipocytes. Redox Rep 2010;15:131-137.
22. Kamiya T, Makino J, Hara H, Inagaki N, Adachi T. Extracellular-superoxide dismutase expression during monocytic differentiation of U937 cells. J Cell Biochem 2011;112: 244-255.
23. Tsukano H, Gotoh T, Endo M, Miyata K, Tazume H, Kadomatsu T, Yano M, Iwawaki T, Kohno K, Araki K, Mizuta H, Oike Y. The endoplasmic reticulum stress-CHOP pathway-mediated apoptosis in macrophages contributes to the instability of atherosclerotic plaques. Arterioscler Thromb Vasc Biol 2010;30:1925-1932.
24. Hotamisligil GS. Endoplasmic reticulum stress and atherosclerosis. Nat Med 2010;16:396-399.
25. Izuta H, Matsunaga N, Shimazawa M, Sugiyama T, Ikeda T, Hara H. Proliferative diabetic retinopathy and relations among antioxidant activity, oxidative stress, and VEGF in the vitreous body. Mol Vis 2010;16:130-136.
26. Ozcan U, Cao Q, Yilmaz E, Lee AH, Iwakoshi NN, Ozdelen E, Tuncman G, Gorgun C, Glimcher LH, Hotamisligil GS. Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science 2004; 306:457-461. (Pubitemid 39372439)
27. Laurila JP, Laatikainen LE, Castellone MD, Laukkanen MO. SOD3 reduces inflammatory cell migration by regulating adhesion molecule and cytokine expression. PLoS One 2009;4: e5786-e5793.
28. Heistad DD. Oxidative stress and vascular disease: 2005 Duff lecture. Arterioscler Thromb Vasc Biol 2006;26:689-695. (Pubitemid 43732139)
29. Takatsu H, Tasaki H, Kim HN, Ueda S, Tsutsui M, Yamashita K, Toyokawa T, Morimoto Y, Nakashima Y, Adachi T. Overexpression of EC-SOD suppresses endothelialcell-mediated LDL oxidation. Biochem Biophys Res Commun 2001;285:84-91. (Pubitemid 32912513)
30. Adachi T, Toishi T, Takashima E, Hara H. Infliximab neutralizes the suppressive effect of TNF-on expression of extracellular-superoxide dismutase in vitro . Biol Pharm Bull 2006;29:2095-2098. (Pubitemid 44510815)
31. Werno C, Zhou J, Brune B. A23187, ionomycin and thapsigargin upregulate mRNA of HIF-1 via endoplasmic reticulum stress rather than a rise in intracellular calcium. J Cell Physiol 2008;215:708-714. (Pubitemid 351632692)
32. Hara H, Kamiya T, Adachi T. Endoplasmic reticulum stress inducers provide protection against 6-hydroxydopamineinduced cytotoxicity Neurochem Int 2010;58:35-43.