Centrally administered resistin enhances sympathetic nerve activity to the hindlimb but attenuates the activity to brown adipose tissue

Endocrinology

Volumn 152, Issue 7, 2011, Pages 2626-2633

  Kosari, S ^a,a   Rathner, J A ^b   Chen, F ^a   Badoer, Emilio ^a  

^a RMIT UNIVERSITY   (Australia)

^b LA TROBE UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN FOS; RESISTIN;

ANIMAL TISSUE; ARTERIAL PRESSURE; ARTICLE; BODY TEMPERATURE; BROWN ADIPOSE TISSUE; CARDIOVASCULAR FUNCTION; CONTROLLED STUDY; DIABETES MELLITUS; ENERGY; HEART RATE; HINDLIMB; HYPOTHALAMUS; LATERAL BRAIN VENTRICLE; MEAN ARTERIAL PRESSURE; METABOLIC REGULATION; NERVE CONDUCTION; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN HOMEOSTASIS; RAT; SYMPATHETIC NERVE; SYMPATHETIC NERVE ACTIVITY;

ADIPOSE TISSUE, BROWN; ANIMALS; BODY TEMPERATURE REGULATION; DOWN-REGULATION; HEMODYNAMICS; HINDLIMB; HYPOTHALAMUS; INJECTIONS, INTRAVENTRICULAR; LUMBOSACRAL REGION; MALE; MUSCLE, SKELETAL; NERVE TISSUE PROTEINS; NEURONS; ORGAN SPECIFICITY; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS; RESISTIN; SYMPATHETIC NERVOUS SYSTEM; SYNAPTIC TRANSMISSION; UP-REGULATION;

EID: 79959406271     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2010-1492     Document Type: Article

References (31)

1. Steppan CM, Bailey ST, Bhat S, Brown EJ, Banerjee RR, Wright CM, Patel HR, Ahima RS, Lazar MA 2001 The hormone resistin links obesity to diabetes. Nature 409:307-312 (Pubitemid 32151228)
2. Morash BA, Willkinson D, Ur E, Wilkinson M 2002 Resistin expression and regulation in mouse pituitary. FEBS Lett 526:26-30 (Pubitemid 35245686)
3. Yang RZ, Huang Q, Xu A, McLenithan JC, Eisen JA, Shuldiner AR, Alkan S, Gong DW, Eison JA 2003 Comparative studies of resistin expression and phylogenomics in human and mouse. Biochem Biophys Res Commun 310:927-935 (Pubitemid 37188711)
4. Rajala MW, Qi Y, Patel HR, Takahashi N, Banerjee R, Pajvani UB, Sinha MK, Gingerich RL, Scherer PE, Ahima RS 2004 Regulation of resistin expression and circulating levels in obesity, diabetes, and fasting. Diabetes 53:1671-1679 (Pubitemid 38857023)
5. McTernan PG, McTernan CL, Chetty R, Jenner K, Fisher FM, Lauer MN, Crocker J, Barnett AH, Kumar S 2002 Increased resistin gene and protein expression in human abdominal adipose tissue. J Clin Endocrinol Metab 87:2407
6. de Luis DA, Gonzalez Sagrado M, Conde R, Aller R, Izaola O, Perez Castrillon JL, Dueñas A 2009 Relation of resistin levels with cardiovascular risk factors and insulin resistance in non-diabetes obese patients. Diabetes Res Clin Pract 84:174-178
7. Piestrzeniewicz K, Luczak K, Komorowski J, Maciejewski M, Jankiewicz Wika J, Goch JH 2008 Resistin increases with obesity and atherosclerotic risk factors in patients with myocardial infarction. Metabolism 57:488-493 (Pubitemid 351317962)
8. Azuma K, Katsukawa F, Oguchi S, Murata M, Yamazaki H, Shimada A, Saruta T 2003 Correlation between serum resistin level and adiposity in obese individuals. Obes Res 11:997-1001 (Pubitemid 41137512)
9. Degawa-Yamauchi M, Bovenkerk JE, Juliar BE, Watson W, Kerr K, Jones R, Zhu Q, Considine RV 2003 Serum resistin (FIZZ3) protein is increased in obese humans. J Clin Endocrinol Metab 88:5452-5455 (Pubitemid 37452753)
10. Kos K, Harte AL, da Silva NF, Tonchev A, Chaldakov G, James S, Snead DR, Hoggart B, O'Hare JP, McTernan PG, Kumar S 2007 Adiponectin and resistin in human cerebrospinal fluid and expression of adiponectin receptors in the human hypothalamus. J Clin Endocrinol Metab 92:1129-1136 (Pubitemid 46465692)
11. Vázquez MJ, González CR, Varela L, Lage R, Tovar S, Sangiao-Alvarellos S, Williams LM, Vidal-Puig A, Nogueiras R, López M, Diéguez C 2008 Central resistin regulates hypothalamic and peripheral lipid metabolism in a nutritional-dependent fashion. Endocrinology 149:4534-4543
12. Bjørbaek C, Kahn BB 2004 Leptin signaling in the central nervous system and the periphery. Recent Prog Horm Res 59:305-331
13. Håkansson ML, Hulting AL, Meister B 1996 Expression of leptin receptor mRNA in the hypothalamic arcuate nucleus: relationship with NPY neurones. Neuroreport 7:3087-3092 (Pubitemid 26426396)
14. Frankel DS, Vasan RS, D'Agostino Sr RB, Benjamin EJ, Levy D, Wang TJ, Meigs JB 2009 Resistin, adiponectin, and risk of heart failure the framingham offspring study. J Am Coll Cardiol 53:754-762
15. Butler J, Kalogeropoulos A, Georgiopoulou V, de Rekeneire N, Rodondi N, Smith AL, Hoffmann U, Kanaya A, Newman AB, Kritchevsky SB, Vasan RS, Wilson PW, Harris TB 2009 Serum resistin concentrations and risk of new onset heart failure in older persons: the health, aging, and body composition (Health ABC) study. Arterioscler Thromb Vasc Biol 29:1144-1149
16. Papadopoulos DP, Perrea D, Thomopoulos C, Sanidas E, Daskalaki M, Papazachou U, Votteas V, Makris T 2009 Masked hypertension and atherogenesis: the impact on adiponectin and resistin plasma levels. J Clin Hypertens (Greenwich) 11:61-65
17. Thomopoulos C, Daskalaki M, Papazachou O, Rodolakis N, Bratsas A, Papadopoulos DP, Papavasileiou MV, Perrea D, Makris T 2011 Association of resistin and adiponectin with different clinical blood pressure phenotypes. J Hum Hypertens 25:38-46
18. Alvarez GE, Beske SD, Ballard TP, Davy KP 2002 Sympathetic neural activation in visceral obesity. Circulation 106:2533-2536 (Pubitemid 35340687)
19. Ahima RS, Lazar MA 2008 Adipokines and the peripheral and neural control of energy balance. Mol Endocrinol 22:1023-1031 (Pubitemid 351629604)
20. Tovar S, Nogueiras R, Tung LY, Castañeda TR, Vázquez MJ, Morris A, Williams LM, Dickson SL, Diéguez C 2005 Central administration of resistin promotes short-term satiety in rats. Eur J Endocrinol 153:R1-R5 (Pubitemid 41410504)
21. Ohmori R, Momiyama Y, Kato R, Taniguchi H, Ogura M, Ayaori M, Nakamura H, Ohsuzu F 2005 Associations between serum resistin levels and insulin resistance, inflammation, and coronary artery disease. J Am Coll Cardiol 46:379-380 (Pubitemid 40966873)
22. Pischon T, Bamberger CM, Kratzsch J, Zyriax BC, Algenstaedt P, Boeing H, Windler E 2005 Association of plasma resistin levels with coronary heart disease in women. Obes Res 13:1764-1771
23. Takeishi Y, Niizeki T, Arimoto T, Nozaki N, Hirono O, Nitobe J, Watanabe T, Takabatake N, Kubota I 2007 Serum resistin is associated with high risk in patients with congestive heart failure: a novel link between metabolic signals and heart failure. Circ J 71:460-464
24. Rahmouni K, Haynes WG, Morgan DA, Mark AL 2003 Intracellular mechanisms involved in leptin regulation of sympathetic outflow. Hypertension 41:763-767 (Pubitemid 36314588)
25. Hausberg M, Morgan DA, Mitchell JL, Sivitz WI, Mark AL, Haynes WG 2002 Leptin potentiates thermogenic sympathetic responses to hypothermia: a receptor-mediated effect. Diabetes 51:2434-2440 (Pubitemid 34827391)
26. Rahmouni K, Sigmund CD, Haynes WG, Mark AL 2009 Hypothalamic ERK mediates the anorectic and thermogenic sympathetic effects of leptin. Diabetes 58:536-542
27. Banerjee RR, Rangwala SM, Shapiro JS, Rich AS, Rhoades B, Qi Y, Wang J, Rajala MW, Pocai A, Scherer PE, Steppan CM, Ahima RS, Obici S, Rossetti L, Lazar MA 2004 Regulation of fasted blood glucose by resistin. Science 303:1195-1198 (Pubitemid 38233585)
28. Nedergaard J, Bengtsson T, Cannon B 2007 Unexpected evidence for active brown adipose tissue in adult humans. Am J Physiol Endocrinol Metab 293:E444-E452 (Pubitemid 47205086)
29. Rothwell NJ, Stock MJ 1983 Luxuskonsumption, diet-induced thermogenesis and brown fat: the case in favour. Clin Sci (Lond) 64:19-23 (Pubitemid 13207247)
30. Singhal NS, Lazar MA, Ahima RS 2007 Central resistin induces hepatic insulin resistance via neuropeptide Y. J Neurosci 27:12924-12932 (Pubitemid 350159588)
31. Madden CJ, Morrison SF 2009 Neurons in the paraventricular nucleus of the hypothalamus inhibit sympathetic outflow to brown adipose tissue. Am J Physiol Regul Integr Comp Physiol 296:R831-R843