Essential role of factor B of the alternative complement pathway in complement activation and opsonophagocytosis during acute pneumococcal otitis media in mice

Infection and Immunity

Volumn 79, Issue 7, 2011, Pages 2578-2585

  Li, Qian ^a,d   Li, Yong Xing ^a   Stahl, Gregory L ^b   Thurman, Joshua M ^c   He, Yujuan ^a,e   Tong, Hua Hua ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^d FUDAN UNIVERSITY   (China)

^e CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALTERNATIVE COMPLEMENT PATHWAY C3 C5 CONVERTASE; COMPLEMENT COMPONENT C1Q; COMPLEMENT COMPONENT C1QA; COMPLEMENT COMPONENT C3 RECEPTOR; UNCLASSIFIED DRUG;

ACUTE OTITIS MEDIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COMPLEMENT ACTIVATION; COMPLEMENT ALTERNATIVE PATHWAY; COMPLEMENT DEFICIENCY; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITHELIUM; FEMALE; GENE EXPRESSION; IMMUNE RESPONSE; IMMUNOFLUORESCENCE; IMMUNOPATHOGENESIS; INNATE IMMUNITY; LAVAGE; MALE; MIDDLE EAR; MOUSE; NONHUMAN; OPSONIZATION; OPSONOPHAGOCYTOSIS; PNEUMOCOCCAL INFECTION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; STREPTOCOCCUS PNEUMONIAE; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; COMPLEMENT ACTIVATION; COMPLEMENT C2; COMPLEMENT C3; COMPLEMENT FACTOR B; COMPLEMENT PATHWAY, ALTERNATIVE; EAR, MIDDLE; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITHELIUM; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OTITIS MEDIA; PHAGOCYTOSIS; PNEUMOCOCCAL INFECTIONS; POLYMERASE CHAIN REACTION; STREPTOCOCCUS PNEUMONIAE;

EID: 79959398474     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00168-11     Document Type: Article

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