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Volumn 270, Issue 2, 2011, Pages 110-122

Antiphospholipid syndrome: Laboratory detection, mechanisms of action and treatment

Author keywords

Arterial thromboembolism; Foetal loss; Laboratory testing; Pregnancy complications; Venous thromboembolism

Indexed keywords

ACETYLSALICYLIC ACID; ANTIVITAMIN K; CARDIOLIPIN ANTIBODY; CYCLOPHOSPHAMIDE; GLYCOPROTEIN 1 BETA2 ANTIBODY; GLYCOPROTEIN IB; HEPARIN; IMMUNOGLOBULIN; LOW MOLECULAR WEIGHT HEPARIN; LUPUS ANTICOAGULANT; METHYLPREDNISOLONE; PHOSPHOLIPID ANTIBODY; PROTEIN ANTIBODY; RITUXIMAB; UNCLASSIFIED DRUG;

EID: 79959382588     PISSN: 09546820     EISSN: 13652796     Source Type: Journal    
DOI: 10.1111/j.1365-2796.2011.02362.x     Document Type: Review
Times cited : (101)

References (112)
  • 1
    • 33344458573 scopus 로고    scopus 로고
    • International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS)
    • Miyakis S, Lockshin MD, Atsumi T et al. International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS). J Thromb Haemost 2006; 4: 295-306.
    • (2006) J Thromb Haemost , vol.4 , pp. 295-306
    • Miyakis, S.1    Lockshin, M.D.2    Atsumi, T.3
  • 2
    • 0021029327 scopus 로고
    • Anticardiolipin antibodies: detection by radioimmunoassay and association with thrombosis in systemic lupus erythematosus
    • Harris EN, Gharavi AE, Boey ML et al. Anticardiolipin antibodies: detection by radioimmunoassay and association with thrombosis in systemic lupus erythematosus. Lancet 1983; 2: 1211-4.
    • (1983) Lancet , vol.2 , pp. 1211-1214
    • Harris, E.N.1    Gharavi, A.E.2    Boey, M.L.3
  • 3
    • 0022178199 scopus 로고
    • Measurement of anti-cardiolipin antibodies by an enzyme-linked immunosorbent assay (ELISA): standardization and quantitation of results
    • Loizou S, McCrea JD, Rudge AC, Reynolds R, Boyle CC, Harris EN. Measurement of anti-cardiolipin antibodies by an enzyme-linked immunosorbent assay (ELISA): standardization and quantitation of results. Clin Exp Immunol 1985; 62: 738-45.
    • (1985) Clin Exp Immunol , vol.62 , pp. 738-745
    • Loizou, S.1    McCrea, J.D.2    Rudge, A.C.3    Reynolds, R.4    Boyle, C.C.5    Harris, E.N.6
  • 4
    • 84941817790 scopus 로고
    • Thrombosis, recurrent fetal loss, and thrombocytopenia. Predictive value of the anticardiolipin antibody test
    • Harris EN, Chan JK, Asherson RA, Aber VR, Gharavi AE, Hughes GR. Thrombosis, recurrent fetal loss, and thrombocytopenia. Predictive value of the anticardiolipin antibody test. Arch Intern Med 1986; 146: 2153-6.
    • (1986) Arch Intern Med , vol.146 , pp. 2153-2156
    • Harris, E.N.1    Chan, J.K.2    Asherson, R.A.3    Aber, V.R.4    Gharavi, A.E.5    Hughes, G.R.6
  • 5
    • 0025500242 scopus 로고
    • Special report. The Second International Anti-cardiolipin Standardization Workshop/the Kingston Anti-Phospholipid Antibody Study (KAPS) group
    • Harris EN. Special report. The Second International Anti-cardiolipin Standardization Workshop/the Kingston Anti-Phospholipid Antibody Study (KAPS) group. Am J Clin Pathol 1990; 94: 476-84.
    • (1990) Am J Clin Pathol , vol.94 , pp. 476-484
    • Harris, E.N.1
  • 6
    • 0028083763 scopus 로고
    • Anticardiolipin wet workshop report. Fifth International Symposium on antiphospholipid antibodies
    • Harris EN, Pierangeli S, Birch D. Anticardiolipin wet workshop report. Fifth International Symposium on antiphospholipid antibodies. Am J Clin Pathol 1994; 101: 616-24.
    • (1994) Am J Clin Pathol , vol.101 , pp. 616-624
    • Harris, E.N.1    Pierangeli, S.2    Birch, D.3
  • 7
    • 0031975978 scopus 로고    scopus 로고
    • An antiphospholipid wet workshop: 7th International Symposium on Antiphospholipid Antibodies
    • Pierangeli SS, Stewart M, Silva LK, Harris EN. An antiphospholipid wet workshop: 7th International Symposium on Antiphospholipid Antibodies. J Rheumatol 1998; 25: 156-60.
    • (1998) J Rheumatol , vol.25 , pp. 156-160
    • Pierangeli, S.S.1    Stewart, M.2    Silva, L.K.3    Harris, E.N.4
  • 8
    • 0025348382 scopus 로고
    • Interlaboratory inconsistencies in detection of anticardiolipin antibodies
    • Coulam CB, McIntyre JA, Wagenknecht D, Rote N. Interlaboratory inconsistencies in detection of anticardiolipin antibodies. Lancet 1990; 335: 865.
    • (1990) Lancet , vol.335 , pp. 865
    • Coulam, C.B.1    McIntyre, J.A.2    Wagenknecht, D.3    Rote, N.4
  • 9
    • 0026735190 scopus 로고
    • Interlaboratory variation in antiphospholipid antibody testing
    • discussion 1784-7.
    • Peaceman AM, Silver RK, MacGregor SN, Socol ML. Interlaboratory variation in antiphospholipid antibody testing. Am J Obstet Gynecol 1992; 166(6 Pt 1): 1780-4. discussion 1784-7.
    • (1992) Am J Obstet Gynecol , vol.166 , Issue.6 PART 1 , pp. 1780-1784
    • Peaceman, A.M.1    Silver, R.K.2    MacGregor, S.N.3    Socol, M.L.4
  • 10
    • 0036780682 scopus 로고    scopus 로고
    • Assessing the usefulness of anticardiolipin antibody assays: a cautious approach is suggested by high variation and limited consensus in multilaboratory testing
    • Favaloro EJ, Silvestrini R. Assessing the usefulness of anticardiolipin antibody assays: a cautious approach is suggested by high variation and limited consensus in multilaboratory testing. Am J Clin Pathol 2002; 118: 548-57.
    • (2002) Am J Clin Pathol , vol.118 , pp. 548-557
    • Favaloro, E.J.1    Silvestrini, R.2
  • 11
    • 34247336928 scopus 로고    scopus 로고
    • Antiphospholipid antibody ELISAs: survey on the performance of clinical laboratories assessed by using lyophilized affinity-purified IgG with anticardiolipin and anti-beta2-Glycoprotein I activity
    • Italian Federation of Anticoagulation Clinics (FCSA).
    • Pengo V, Biasiolo A, Bison E, Chantarangkul V, Tripodi A, Italian Federation of Anticoagulation Clinics (FCSA). Antiphospholipid antibody ELISAs: survey on the performance of clinical laboratories assessed by using lyophilized affinity-purified IgG with anticardiolipin and anti-beta2-Glycoprotein I activity. Thromb Res 2007; 120: 127-33.
    • (2007) Thromb Res , vol.120 , pp. 127-133
    • Pengo, V.1    Biasiolo, A.2    Bison, E.3    Chantarangkul, V.4    Tripodi, A.5
  • 12
    • 34147204285 scopus 로고    scopus 로고
    • A Review of beta2-glycoprotein-l antibody testing results from a peer-driven multilaboratory quality assurance program
    • Favaloro EJ, Wong RC, Jovanovich S, Roberts-Thomson P. A Review of beta2-glycoprotein-l antibody testing results from a peer-driven multilaboratory quality assurance program. Am J Clin Pathol 2007; 127: 441-8.
    • (2007) Am J Clin Pathol , vol.127 , pp. 441-448
    • Favaloro, E.J.1    Wong, R.C.2    Jovanovich, S.3    Roberts-Thomson, P.4
  • 13
    • 64849111086 scopus 로고    scopus 로고
    • Anti-beta(2)-glycoprotein I ELISA assay: the influence of different antigen preparations
    • Cavazzana A, Pengo V, Tonello M et al. Anti-beta(2)-glycoprotein I ELISA assay: the influence of different antigen preparations. Thromb Haemost 2009; 101: 789-91.
    • (2009) Thromb Haemost , vol.101 , pp. 789-791
    • Cavazzana, A.1    Pengo, V.2    Tonello, M.3
  • 14
    • 53049091449 scopus 로고    scopus 로고
    • Laboratory testing for lupus anticoagulants: diagnostic criteria and use of screening, mixing, and confirmatory studies
    • Tripodi A. Laboratory testing for lupus anticoagulants: diagnostic criteria and use of screening, mixing, and confirmatory studies. Semin Thromb Hemost 2008; 34: 373-9.
    • (2008) Semin Thromb Hemost , vol.34 , pp. 373-379
    • Tripodi, A.1
  • 15
    • 34247894036 scopus 로고    scopus 로고
    • Survey of lupus anticoagulant diagnosis by central evaluation of positive plasma samples
    • Participating Centres of Italian Federation of Thrombosis Centres (FCSA).
    • Pengo V, Biasiolo A, Gresele P et al., Participating Centres of Italian Federation of Thrombosis Centres (FCSA). Survey of lupus anticoagulant diagnosis by central evaluation of positive plasma samples. J Thromb Haemost 2007; 5: 925-30.
    • (2007) J Thromb Haemost , vol.5 , pp. 925-930
    • Pengo, V.1    Biasiolo, A.2    Gresele, P.3
  • 16
    • 0028810205 scopus 로고
    • Criteria for the diagnosis of lupus anticoagulants: an update. On behalf of the Subcommittee on Lupus Anticoagulant/Antiphospholipid Antibody of the Scientific and Standardisation Committee of the ISTH
    • Brandt JT, Triplett DA, Alving B, Scharrer I. Criteria for the diagnosis of lupus anticoagulants: an update. On behalf of the Subcommittee on Lupus Anticoagulant/Antiphospholipid Antibody of the Scientific and Standardisation Committee of the ISTH. Thromb Haemost 1995; 74: 1185-90.
    • (1995) Thromb Haemost , vol.74 , pp. 1185-1190
    • Brandt, J.T.1    Triplett, D.A.2    Alving, B.3    Scharrer, I.4
  • 17
    • 70350004861 scopus 로고    scopus 로고
    • Update of the guidelines for lupus anticoagulant detection
    • Pengo V, Tripodi A, Reber G et al. Update of the guidelines for lupus anticoagulant detection. J Thromb Haemost 2009; 7: 1737-40.
    • (2009) J Thromb Haemost , vol.7 , pp. 1737-1740
    • Pengo, V.1    Tripodi, A.2    Reber, G.3
  • 18
    • 0029936253 scopus 로고    scopus 로고
    • False negative screening tests for lupus anticoagulants - an unrecognized problem?
    • Jacobsen EM, Wisløff F. False negative screening tests for lupus anticoagulants - an unrecognized problem? Thromb Res 1996; 82: 445-51.
    • (1996) Thromb Res , vol.82 , pp. 445-451
    • Jacobsen, E.M.1    Wisløff, F.2
  • 19
    • 77953773213 scopus 로고    scopus 로고
    • No more mixing tests required for integrated assay systems in the laboratory diagnosis of lupus anticoagulants?
    • Devreese KM. No more mixing tests required for integrated assay systems in the laboratory diagnosis of lupus anticoagulants? J Thromb Haemost 2010; 8: 1120-2.
    • (2010) J Thromb Haemost , vol.8 , pp. 1120-1122
    • Devreese, K.M.1
  • 20
    • 25444528227 scopus 로고    scopus 로고
    • Lupus anticoagulants and their relationship with the inhibitors against coagulation factor VIII. Considerations on the differentiation between the two circulating anticoagulants
    • Tripodi A, Mancuso ME, Chantarangkul V et al. Lupus anticoagulants and their relationship with the inhibitors against coagulation factor VIII. Considerations on the differentiation between the two circulating anticoagulants. Clin Chem 2005; 51: 1883-5.
    • (2005) Clin Chem , vol.51 , pp. 1883-1885
    • Tripodi, A.1    Mancuso, M.E.2    Chantarangkul, V.3
  • 21
    • 0037217897 scopus 로고    scopus 로고
    • Thrombogenicity of beta 2-glycoprotein I-dependent antiphospholipid antibodies in a photochemically induced thrombosis model in the hamster
    • Jankowski M, Vreys I, Wittevrongel C et al. Thrombogenicity of beta 2-glycoprotein I-dependent antiphospholipid antibodies in a photochemically induced thrombosis model in the hamster. Blood 2003; 101: 157-62.
    • (2003) Blood , vol.101 , pp. 157-162
    • Jankowski, M.1    Vreys, I.2    Wittevrongel, C.3
  • 22
    • 50249189294 scopus 로고    scopus 로고
    • Antiphospholipid antibodies and the antiphospholipid syndrome: pathogenic mechanisms
    • Pierangeli SS, Chen PP, Raschi E et al. Antiphospholipid antibodies and the antiphospholipid syndrome: pathogenic mechanisms. Semin Thromb Hemost 2008; 34: 236-50.
    • (2008) Semin Thromb Hemost , vol.34 , pp. 236-250
    • Pierangeli, S.S.1    Chen, P.P.2    Raschi, E.3
  • 23
    • 0037370733 scopus 로고    scopus 로고
    • Lupus anticoagulants are stronger risk factors for thrombosis than anticardioplipin antibodies in the antiphospholipid syndrome: a systematic review of the literature
    • Galli M, Luciani D, Bertolini G, Barbui T. Lupus anticoagulants are stronger risk factors for thrombosis than anticardioplipin antibodies in the antiphospholipid syndrome: a systematic review of the literature. Blood 2003; 101: 1827-32.
    • (2003) Blood , vol.101 , pp. 1827-1832
    • Galli, M.1    Luciani, D.2    Bertolini, G.3    Barbui, T.4
  • 24
    • 0033512274 scopus 로고    scopus 로고
    • International consensus statement on preliminary classification criteria for definite antiphospholipid syndrome: report of an international workshop
    • Wilson WA, Gharavi AE, Koike T et al. International consensus statement on preliminary classification criteria for definite antiphospholipid syndrome: report of an international workshop. Arthritis Rheum 1999; 42: 1309-11.
    • (1999) Arthritis Rheum , vol.42 , pp. 1309-1311
    • Wilson, W.A.1    Gharavi, A.E.2    Koike, T.3
  • 25
    • 7044223470 scopus 로고    scopus 로고
    • Beta 2-glycoprotein I-dependent lupus anticoagulant highly correlates with thrombosis in the antiphospholipid syndrome
    • de Laat HB, Derksen RHWM, Urbanus RT, Roest M, de Groot PG. Beta 2-glycoprotein I-dependent lupus anticoagulant highly correlates with thrombosis in the antiphospholipid syndrome. Blood 2004; 104: 3598-602.
    • (2004) Blood , vol.104 , pp. 3598-3602
    • de Laat, H.B.1    Derksen, R.H.W.M.2    Urbanus, R.T.3    Roest, M.4    de Groot, P.G.5
  • 26
    • 0014226946 scopus 로고
    • On a hereditary beta-2-glycoprotein I deficiency
    • Haupt H, Schwick HG, Störiko K. On a hereditary beta-2-glycoprotein I deficiency. Humangenetik 1968; 5: 291-3.
    • (1968) Humangenetik , vol.5 , pp. 291-293
    • Haupt, H.1    Schwick, H.G.2    Störiko, K.3
  • 27
  • 28
    • 77956488547 scopus 로고    scopus 로고
    • {beta}2-Glycoprotein I can exist in two conformations: implications for our understanding of the antiphospholipid syndrome
    • Agar C, van Os GM, Mörgelin M et al. {beta}2-Glycoprotein I can exist in two conformations: implications for our understanding of the antiphospholipid syndrome. Blood 2010; 116: 1336-43.
    • (2010) Blood , vol.116 , pp. 1336-1343
    • Agar, C.1    van Os, G.M.2    Mörgelin, M.3
  • 29
    • 0024433923 scopus 로고
    • Impaired catalytic function of activated protein C: a new in vitro manifestation of lupus anticoagulant
    • Marciniak E, Romond EH. Impaired catalytic function of activated protein C: a new in vitro manifestation of lupus anticoagulant. Blood 1989; 74: 2426-32.
    • (1989) Blood , vol.74 , pp. 2426-2432
    • Marciniak, E.1    Romond, E.H.2
  • 30
    • 0027253088 scopus 로고
    • Antiphospholipid antibodies are directed to a combination of phospholipids with prothrombin, protein C or protein S. An explanation for their pathogenic mechanism?
    • Oosting JD, Derksen RHWM, Bobbink IWG, Hackeng T, Bouma BN, de Groot PG. Antiphospholipid antibodies are directed to a combination of phospholipids with prothrombin, protein C or protein S. An explanation for their pathogenic mechanism? Blood 1993; 81: 2618-25.
    • (1993) Blood , vol.81 , pp. 2618-2625
    • Oosting, J.D.1    Derksen, R.H.W.M.2    Bobbink, I.W.G.3    Hackeng, T.4    Bouma, B.N.5    de Groot, P.G.6
  • 31
    • 0027131583 scopus 로고
    • Autoantibodies directed against the epidermal growth factor-like domains of thrombomodulin inhibit protein C activation in vitro
    • Oosting JD, Preissner KT, Derksen RHWM, de Groot PG. Autoantibodies directed against the epidermal growth factor-like domains of thrombomodulin inhibit protein C activation in vitro. Br J Haematol 1993; 85: 761-8.
    • (1993) Br J Haematol , vol.85 , pp. 761-768
    • Oosting, J.D.1    Preissner, K.T.2    Derksen, R.H.W.M.3    de Groot, P.G.4
  • 32
    • 0032521453 scopus 로고    scopus 로고
    • Differential effects of anti-beta2-glycoprotein I and antiprothrombin antibodies on the anticoagulant activity of activated protein C
    • Galli M, Ruggeri L, Barbui T. Differential effects of anti-beta2-glycoprotein I and antiprothrombin antibodies on the anticoagulant activity of activated protein C. Blood 1998; 91: 1999-2004.
    • (1998) Blood , vol.91 , pp. 1999-2004
    • Galli, M.1    Ruggeri, L.2    Barbui, T.3
  • 33
    • 4444301246 scopus 로고    scopus 로고
    • Autoantibodies against EPCR are found in antiphospholipid syndrome and are a risk factor for fetal death
    • Hurtado V, Montes R, Gris JC et al. Autoantibodies against EPCR are found in antiphospholipid syndrome and are a risk factor for fetal death. Blood 2004; 104: 1369-74.
    • (2004) Blood , vol.104 , pp. 1369-1374
    • Hurtado, V.1    Montes, R.2    Gris, J.C.3
  • 34
    • 0029959119 scopus 로고    scopus 로고
    • Mechanism and effects of the binding of lupus anticoagulant IgG and prothrombin to surface phospholipid
    • Rao LV, Hoang AD, Rapaport SI. Mechanism and effects of the binding of lupus anticoagulant IgG and prothrombin to surface phospholipid. Blood 1996; 88: 4173-82.
    • (1996) Blood , vol.88 , pp. 4173-4182
    • Rao, L.V.1    Hoang, A.D.2    Rapaport, S.I.3
  • 35
    • 0033856205 scopus 로고    scopus 로고
    • Phosphatidylserine expression on cell surfaces promotes antibody-dependent aggregation and thrombosis in beta2-glyoprotein I-immune mice
    • Dombroski D, Balasubramanian K, Schroit AJ. Phosphatidylserine expression on cell surfaces promotes antibody-dependent aggregation and thrombosis in beta2-glyoprotein I-immune mice. J Autoimmun 2000; 14: 221-9.
    • (2000) J Autoimmun , vol.14 , pp. 221-229
    • Dombroski, D.1    Balasubramanian, K.2    Schroit, A.J.3
  • 36
    • 0033626575 scopus 로고    scopus 로고
    • Antibodies to beta2-glycoprotein I associated with antiphospholipid syndrome suppress the inhibitory activity of tissue factor pathway inhibitor
    • Salemink I, Blezer R, Willems GM, Galli M, Bevers E, Lindhout T. Antibodies to beta2-glycoprotein I associated with antiphospholipid syndrome suppress the inhibitory activity of tissue factor pathway inhibitor. Thromb Haemost 2000; 84: 653-6.
    • (2000) Thromb Haemost , vol.84 , pp. 653-656
    • Salemink, I.1    Blezer, R.2    Willems, G.M.3    Galli, M.4    Bevers, E.5    Lindhout, T.6
  • 38
    • 33847055815 scopus 로고    scopus 로고
    • Beta2-glycoprotein I binds thrombin via exosite I and exosite II: anti-beta2-glycoprotein I antibodies potentiate the inhibitory effect of beta2-glycoprotein I on thrombin-mediated factor XIa generation
    • Rahgozar S, Yang Q, Giannakopoulos B, Yan X, Miyakis S, Krilis SA. Beta2-glycoprotein I binds thrombin via exosite I and exosite II: anti-beta2-glycoprotein I antibodies potentiate the inhibitory effect of beta2-glycoprotein I on thrombin-mediated factor XIa generation. Arthritis Rheum 2007; 56: 605-13.
    • (2007) Arthritis Rheum , vol.56 , pp. 605-613
    • Rahgozar, S.1    Yang, Q.2    Giannakopoulos, B.3    Yan, X.4    Miyakis, S.5    Krilis, S.A.6
  • 39
    • 0034995524 scopus 로고    scopus 로고
    • Antibodies to factor XII and recurrent fetal loss in patients with the anti-phospholipid syndrome
    • Jones DW, MacKie IJ, Gallimore MJ, Winter M. Antibodies to factor XII and recurrent fetal loss in patients with the anti-phospholipid syndrome. Br J Haematol 2001; 113: 550-2.
    • (2001) Br J Haematol , vol.113 , pp. 550-552
    • Jones, D.W.1    MacKie, I.J.2    Gallimore, M.J.3    Winter, M.4
  • 40
    • 42449145853 scopus 로고    scopus 로고
    • Beta2-glycoprotein I protects thrombin from inhibition by heparin cofactor II: potentiation of this effect in the presence of anti-beta2-glycoprotein I autoantibodies
    • Rahgozar S, Giannakopoulos B, Yan X et al. Beta2-glycoprotein I protects thrombin from inhibition by heparin cofactor II: potentiation of this effect in the presence of anti-beta2-glycoprotein I autoantibodies. Arthritis Rheum 2008; 58: 1146-55.
    • (2008) Arthritis Rheum , vol.58 , pp. 1146-1155
    • Rahgozar, S.1    Giannakopoulos, B.2    Yan, X.3
  • 41
    • 0036182182 scopus 로고    scopus 로고
    • Fluctuations in levels of antiphospholipid antibodies and increased coagulation activation markers in normal and heparin-treated antiphospholipid syndrome pregnancies
    • Donohoe S, Quenby S, Mackie I et al. Fluctuations in levels of antiphospholipid antibodies and increased coagulation activation markers in normal and heparin-treated antiphospholipid syndrome pregnancies. Lupus 2002; 11: 11-20.
    • (2002) Lupus , vol.11 , pp. 11-20
    • Donohoe, S.1    Quenby, S.2    Mackie, I.3
  • 42
    • 0033485643 scopus 로고    scopus 로고
    • Procoagulant effect of anti-beta2-glycoprotein I antibodies with lupus anticoagulant activity
    • Pengo V, Brocco T, Biasiolo A, Rampazzo P, Carraro P, Zamarchi R. Procoagulant effect of anti-beta2-glycoprotein I antibodies with lupus anticoagulant activity. Blood 1999; 94: 3814-9.
    • (1999) Blood , vol.94 , pp. 3814-3819
    • Pengo, V.1    Brocco, T.2    Biasiolo, A.3    Rampazzo, P.4    Carraro, P.5    Zamarchi, R.6
  • 43
    • 33846936761 scopus 로고    scopus 로고
    • Correlation between antiphospholipid antibodies that recognize domain I of beta2-glycoprotein I and a reduction in the anticoagulant activity of annexin A5
    • de Laat B, Wu XX, van Lummel M, Derksen RH, de Groot PG, Rand JH. Correlation between antiphospholipid antibodies that recognize domain I of beta2-glycoprotein I and a reduction in the anticoagulant activity of annexin A5. Blood 2007; 109: 1490-4.
    • (2007) Blood , vol.109 , pp. 1490-1494
    • de Laat, B.1    Wu, X.X.2    van Lummel, M.3    Derksen, R.H.4    de Groot, P.G.5    Rand, J.H.6
  • 44
    • 0029855586 scopus 로고    scopus 로고
    • Role of divalency in the high-affinity binding of anticardiolipin antibody-beta 2-glycoprotein I complexes to lipid membranes
    • Willems GM, Janssen MP, Pelsers MM et al. Role of divalency in the high-affinity binding of anticardiolipin antibody-beta 2-glycoprotein I complexes to lipid membranes. Biochemistry 1996; 35: 13833-42.
    • (1996) Biochemistry , vol.35 , pp. 13833-13842
    • Willems, G.M.1    Janssen, M.P.2    Pelsers, M.M.3
  • 45
    • 0030789659 scopus 로고    scopus 로고
    • Pregnancy loss in the antiphospholipid-antibody syndrome - a possible thrombogenic mechanism
    • Rand JH, Wu XX, Andree HA et al. Pregnancy loss in the antiphospholipid-antibody syndrome - a possible thrombogenic mechanism. N Engl J Med 1997; 337: 154-60.
    • (1997) N Engl J Med , vol.337 , pp. 154-160
    • Rand, J.H.1    Wu, X.X.2    Andree, H.A.3
  • 46
    • 0034060984 scopus 로고    scopus 로고
    • No evidence for enhanced thrombin formation through displacement of annexin V by antiphospholipid antibodies
    • Bevers EM, Janssen MP, Willems GM, Zwaal RF. No evidence for enhanced thrombin formation through displacement of annexin V by antiphospholipid antibodies. Thromb Haemost 2000; 83: 792-4.
    • (2000) Thromb Haemost , vol.83 , pp. 792-794
    • Bevers, E.M.1    Janssen, M.P.2    Willems, G.M.3    Zwaal, R.F.4
  • 47
    • 0034728384 scopus 로고    scopus 로고
    • Competition of annexin V and anticardiolipin antibodies for binding to phosphatidylserine containing membranes
    • Willems GM, Janssen MP, Comfurius P, Galli M, Zwaal RF, Bevers EM. Competition of annexin V and anticardiolipin antibodies for binding to phosphatidylserine containing membranes. Biochemistry 2000; 39: 1982-9.
    • (2000) Biochemistry , vol.39 , pp. 1982-1989
    • Willems, G.M.1    Janssen, M.P.2    Comfurius, P.3    Galli, M.4    Zwaal, R.F.5    Bevers, E.M.6
  • 48
    • 0037385228 scopus 로고    scopus 로고
    • Annexin A5 is not essential for skeletal development
    • Brachvogel B, Dikschas J, Moch H et al. Annexin A5 is not essential for skeletal development. Mol Cell Biol 2003; 23: 2907-13.
    • (2003) Mol Cell Biol , vol.23 , pp. 2907-2913
    • Brachvogel, B.1    Dikschas, J.2    Moch, H.3
  • 49
    • 1542373659 scopus 로고    scopus 로고
    • Antibodies to tissue-type plasminogen activator (tPA) in patients with antiphospholipid syndrome: evidence of interaction between the antibodies and the catalytic domain of tPA in 2 patients
    • Cugno M, Cabibbe M, Galli M et al. Antibodies to tissue-type plasminogen activator (tPA) in patients with antiphospholipid syndrome: evidence of interaction between the antibodies and the catalytic domain of tPA in 2 patients. Blood 2004; 103: 2121-6.
    • (2004) Blood , vol.103 , pp. 2121-2126
    • Cugno, M.1    Cabibbe, M.2    Galli, M.3
  • 50
    • 33744481250 scopus 로고    scopus 로고
    • Autoantibodies against the fibrinolytic receptor, annexin 2, in antiphospholipid syndrome
    • Cesarman-Maus G, Ríos-Luna NP, Deora AB et al. Autoantibodies against the fibrinolytic receptor, annexin 2, in antiphospholipid syndrome. Blood 2006; 107: 4375-82.
    • (2006) Blood , vol.107 , pp. 4375-4382
    • Cesarman-Maus, G.1    Ríos-Luna, N.P.2    Deora, A.B.3
  • 51
    • 70350509576 scopus 로고    scopus 로고
    • Nicked {beta}2-glycoprotein I binds angiostatin 4.5 (plasminogen kringle 1-5) and attenuates its antiangiogenic property
    • Nakagawa H, Yasuda S, Matsuura E et al. Nicked {beta}2-glycoprotein I binds angiostatin 4.5 (plasminogen kringle 1-5) and attenuates its antiangiogenic property. Blood 2009; 114: 2553-9.
    • (2009) Blood , vol.114 , pp. 2553-2559
    • Nakagawa, H.1    Yasuda, S.2    Matsuura, E.3
  • 52
    • 77956022279 scopus 로고    scopus 로고
    • Plasma levels of fibrinolytic proteins and the risk of myocardial infarction in men
    • Meltzer ME, Doggen CJ, de Groot PG, Rosendaal FR, Lisman T. Plasma levels of fibrinolytic proteins and the risk of myocardial infarction in men. Blood 2010; 116: 529-36.
    • (2010) Blood , vol.116 , pp. 529-536
    • Meltzer, M.E.1    Doggen, C.J.2    de Groot, P.G.3    Rosendaal, F.R.4    Lisman, T.5
  • 53
    • 0037148520 scopus 로고    scopus 로고
    • Complement C3 activation is required for antiphospholipid antibody-induced fetal loss
    • Holers VM, Girardi G, Mo L et al. Complement C3 activation is required for antiphospholipid antibody-induced fetal loss. J Exp Med 2002; 195: 211-20.
    • (2002) J Exp Med , vol.195 , pp. 211-220
    • Holers, V.M.1    Girardi, G.2    Mo, L.3
  • 54
    • 0346969977 scopus 로고    scopus 로고
    • Complement C5a receptors and neutrophils mediate fetal injury in the antiphospholipid syndrome
    • Girardi G, Berman J, Redecha P et al. Complement C5a receptors and neutrophils mediate fetal injury in the antiphospholipid syndrome. J Clin Invest 2003; 112: 1644-54.
    • (2003) J Clin Invest , vol.112 , pp. 1644-1654
    • Girardi, G.1    Berman, J.2    Redecha, P.3
  • 55
    • 0031035948 scopus 로고    scopus 로고
    • Antiphospholipid antibody-dependent C5b-9 formation
    • Stewart MW, Etches WS, Gordon PA. Antiphospholipid antibody-dependent C5b-9 formation. Br J Haematol 1997; 96: 451-7.
    • (1997) Br J Haematol , vol.96 , pp. 451-457
    • Stewart, M.W.1    Etches, W.S.2    Gordon, P.A.3
  • 56
    • 34948903311 scopus 로고    scopus 로고
    • Tissue factor: a link between C5a and neutrophil activation in antiphospholipid antibody induced fetal injury
    • Redecha P, Tilley R, Tencati M et al. Tissue factor: a link between C5a and neutrophil activation in antiphospholipid antibody induced fetal injury. Blood 2007; 110: 2423-31.
    • (2007) Blood , vol.110 , pp. 2423-2431
    • Redecha, P.1    Tilley, R.2    Tencati, M.3
  • 57
    • 70350279315 scopus 로고    scopus 로고
    • Atypical hemolytic-uremic syndrome
    • Noris M, Remuzzi G. Atypical hemolytic-uremic syndrome. N Engl J Med 2009; 361: 1676-87.
    • (2009) N Engl J Med , vol.361 , pp. 1676-1687
    • Noris, M.1    Remuzzi, G.2
  • 59
    • 33747023522 scopus 로고    scopus 로고
    • Anti-beta2-glycoprotein I antibodies in complex with beta2-glycoprotein I can activate platelets in a dysregulated manner via glycoprotein Ib-IX-V
    • Shi T, Giannakopoulos B, Yan X et al. Anti-beta2-glycoprotein I antibodies in complex with beta2-glycoprotein I can activate platelets in a dysregulated manner via glycoprotein Ib-IX-V. Arthritis Rheum 2006; 54: 2558-67.
    • (2006) Arthritis Rheum , vol.54 , pp. 2558-2567
    • Shi, T.1    Giannakopoulos, B.2    Yan, X.3
  • 60
    • 77449133188 scopus 로고    scopus 로고
    • {beta}2 Glycoprotein I ({beta}2GPI) binds platelet factor 4 (PF4): implications for the pathogenesis of antiphospholipid syndrome
    • Sikara MP, Routsias JG, Samiotaki M, Panayotou G, Moutsopoulos HM, Vlachoyiannopoulos PG. {beta}2 Glycoprotein I ({beta}2GPI) binds platelet factor 4 (PF4): implications for the pathogenesis of antiphospholipid syndrome. Blood 2010; 115: 713-23.
    • (2010) Blood , vol.115 , pp. 713-723
    • Sikara, M.P.1    Routsias, J.G.2    Samiotaki, M.3    Panayotou, G.4    Moutsopoulos, H.M.5    Vlachoyiannopoulos, P.G.6
  • 61
    • 0031594156 scopus 로고    scopus 로고
    • Anti-beta2 glycoprotein I antibodies and platelet activation in patients with antiphospholipid antibodies: association with increased excretion of platelet-derived thromboxane urinary metabolites
    • Forastiero R, Martinuzzo M, Carreras LO, Maclouf J. Anti-beta2 glycoprotein I antibodies and platelet activation in patients with antiphospholipid antibodies: association with increased excretion of platelet-derived thromboxane urinary metabolites. J Thromb Haemost 1998; 79: 42-5.
    • (1998) J Thromb Haemost , vol.79 , pp. 42-45
    • Forastiero, R.1    Martinuzzo, M.2    Carreras, L.O.3    Maclouf, J.4
  • 62
    • 0037528699 scopus 로고    scopus 로고
    • Role of the MyD88 transduction signaling pathway in endothelial activation by antiphospholipid antibodies
    • Raschi E, Testoni C, Bosisio D et al. Role of the MyD88 transduction signaling pathway in endothelial activation by antiphospholipid antibodies. Blood 2003; 101: 3495-500.
    • (2003) Blood , vol.101 , pp. 3495-3500
    • Raschi, E.1    Testoni, C.2    Bosisio, D.3
  • 63
    • 33846899419 scopus 로고    scopus 로고
    • The role of TLR2 in the inflammatory activation of mouse fibroblasts by human antiphospholipid antibodies
    • Satta N, Dunoyer-Geindre S, Reber G et al. The role of TLR2 in the inflammatory activation of mouse fibroblasts by human antiphospholipid antibodies. Blood 2007; 109: 1507-14.
    • (2007) Blood , vol.109 , pp. 1507-1514
    • Satta, N.1    Dunoyer-Geindre, S.2    Reber, G.3
  • 64
    • 84921010338 scopus 로고
    • Vermylen 'Lupus' anticoagulant and prostacyclin
    • Carreras LO. Vermylen 'Lupus' anticoagulant and prostacyclin. Lancet 1981; 1: 665.
    • (1981) Lancet , vol.1 , pp. 665
    • Carreras, L.O.1
  • 65
    • 34547733912 scopus 로고    scopus 로고
    • Anti-beta2-glycoprotein I antibodies induce monocyte release of tumor necrosis factor alpha and tissue factor by signal transduction pathways involving lipid rafts
    • Sorice M, Longo A, Capozzi A et al. Anti-beta2-glycoprotein I antibodies induce monocyte release of tumor necrosis factor alpha and tissue factor by signal transduction pathways involving lipid rafts. Arthritis Rheum 2007; 56: 2687-97.
    • (2007) Arthritis Rheum , vol.56 , pp. 2687-2697
    • Sorice, M.1    Longo, A.2    Capozzi, A.3
  • 66
    • 33748205091 scopus 로고    scopus 로고
    • Endothelial function is impaired in patients with primary antiphospholipid syndrome
    • Stalc M, Poredos P, Peternel P, Tomsic M, Sebestjen M, Kveder T. Endothelial function is impaired in patients with primary antiphospholipid syndrome. Thromb Res 2006; 118: 455-61.
    • (2006) Thromb Res , vol.118 , pp. 455-461
    • Stalc, M.1    Poredos, P.2    Peternel, P.3    Tomsic, M.4    Sebestjen, M.5    Kveder, T.6
  • 67
    • 55849112296 scopus 로고    scopus 로고
    • Neutrophil activation by the tissue factor/Factor VIIa/PAR2 axis mediates fetal death in a mouse model of antiphospholipid syndrome
    • Redecha P, Franzke CW, Ruf W, Mackman N, Girardi G. Neutrophil activation by the tissue factor/Factor VIIa/PAR2 axis mediates fetal death in a mouse model of antiphospholipid syndrome. J Clin Invest 2008; 118: 3453-61.
    • (2008) J Clin Invest , vol.118 , pp. 3453-3461
    • Redecha, P.1    Franzke, C.W.2    Ruf, W.3    Mackman, N.4    Girardi, G.5
  • 68
    • 77951744440 scopus 로고    scopus 로고
    • Decreased expression of heparin-binding epidermal growth factor-like growth factor as a newly identified pathogenic mechanism of antiphospholipid-mediated defective placentation
    • Di Simone N, Marana R, Castellani R et al. Decreased expression of heparin-binding epidermal growth factor-like growth factor as a newly identified pathogenic mechanism of antiphospholipid-mediated defective placentation. Arthritis Rheum 2010; 62: 1504-12.
    • (2010) Arthritis Rheum , vol.62 , pp. 1504-1512
    • Di Simone, N.1    Marana, R.2    Castellani, R.3
  • 69
    • 37349061734 scopus 로고    scopus 로고
    • A systematic review of secondary thromboprophylaxis in patients with antiphospholipid antibodies
    • Ruiz-Irastorza G, Hunt BJ, Khamashta MA. A systematic review of secondary thromboprophylaxis in patients with antiphospholipid antibodies. Arthritis Rheum 2007; 57: 1487-95.
    • (2007) Arthritis Rheum , vol.57 , pp. 1487-1495
    • Ruiz-Irastorza, G.1    Hunt, B.J.2    Khamashta, M.A.3
  • 70
    • 0141791073 scopus 로고    scopus 로고
    • A comparison of two intensities of warfarin for the prevention of recurrent thrombosis in patients with the antiphospholipid antibody syndrome
    • Crowther MA, Ginsberg JS, Julian J et al. A comparison of two intensities of warfarin for the prevention of recurrent thrombosis in patients with the antiphospholipid antibody syndrome. N Engl J Med 2003; 349: 1133-8.
    • (2003) N Engl J Med , vol.349 , pp. 1133-1138
    • Crowther, M.A.1    Ginsberg, J.S.2    Julian, J.3
  • 71
    • 23844437705 scopus 로고    scopus 로고
    • A randomized clinical trial of high-intensity warfarin vs. conventional antithrombotic therapy for the prevention of recurrent thrombosis in patients with the antiphospholipid syndrome (WAPS)
    • Finazzi G, Marchioli R, Brancaccio V et al. A randomized clinical trial of high-intensity warfarin vs. conventional antithrombotic therapy for the prevention of recurrent thrombosis in patients with the antiphospholipid syndrome (WAPS). J Thromb Haemost 2005; 3: 848-53.
    • (2005) J Thromb Haemost , vol.3 , pp. 848-853
    • Finazzi, G.1    Marchioli, R.2    Brancaccio, V.3
  • 72
    • 74749086117 scopus 로고    scopus 로고
    • Clinical course of high-risk patients diagnosed with antiphospholipid syndrome
    • Pengo V, Ruffatti A, Legnani C et al. Clinical course of high-risk patients diagnosed with antiphospholipid syndrome. J Thromb Haemost 2010; 8: 237-42.
    • (2010) J Thromb Haemost , vol.8 , pp. 237-242
    • Pengo, V.1    Ruffatti, A.2    Legnani, C.3
  • 73
    • 1642354879 scopus 로고    scopus 로고
    • Lowering the intensity of oral anticoagulant therapy: effects on the risk of hemorrhage and thromboembolism
    • Torn M, van der Meer FJ, Rosendaal FR. Lowering the intensity of oral anticoagulant therapy: effects on the risk of hemorrhage and thromboembolism. Arch Intern Med 2004; 164: 668-73.
    • (2004) Arch Intern Med , vol.164 , pp. 668-673
    • Torn, M.1    van der Meer, F.J.2    Rosendaal, F.R.3
  • 74
    • 0031919292 scopus 로고    scopus 로고
    • Anticardiolipin antibodies predict early recurrence of thromboembolism and death among patients with venous thromboembolism following anticoagulant therapy
    • Schulman S, Svenungsson E, Granqvist S. Anticardiolipin antibodies predict early recurrence of thromboembolism and death among patients with venous thromboembolism following anticoagulant therapy. Am J Med 1998; 104: 332-8.
    • (1998) Am J Med , vol.104 , pp. 332-338
    • Schulman, S.1    Svenungsson, E.2    Granqvist, S.3
  • 75
    • 45949100970 scopus 로고    scopus 로고
    • Antithrombotic Therapy for Venous Thromboembolic Disease: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition)
    • Kearon C, Kahn SR, Agnelli G, Goldhaber S, Raskob GE, Comerota AJ. Antithrombotic Therapy for Venous Thromboembolic Disease: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest 2008; 133: 454-545.
    • (2008) Chest , vol.133 , pp. 454-545
    • Kearon, C.1    Kahn, S.R.2    Agnelli, G.3    Goldhaber, S.4    Raskob, G.E.5    Comerota, A.J.6
  • 76
    • 65649094470 scopus 로고    scopus 로고
    • Residual thrombosis on ultrasonography to guide the duration of anticoagulation in patients with deep venous thrombosis: a randomized trial
    • AESOPUS Investigators.
    • Prandoni P, Prins MH, Lensing AW et al., AESOPUS Investigators. Residual thrombosis on ultrasonography to guide the duration of anticoagulation in patients with deep venous thrombosis: a randomized trial. Ann Intern Med 2009; 150: 577-85.
    • (2009) Ann Intern Med , vol.150 , pp. 577-585
    • Prandoni, P.1    Prins, M.H.2    Lensing, A.W.3
  • 77
    • 33750336183 scopus 로고    scopus 로고
    • D-dimer testing to determine the duration of anticoagulation therapy
    • PROLONG Investigators.
    • Palareti G, Cosmi B, Legnani C et al., PROLONG Investigators. D-dimer testing to determine the duration of anticoagulation therapy. N Engl J Med 2006; 355: 1780-9.
    • (2006) N Engl J Med , vol.355 , pp. 1780-1789
    • Palareti, G.1    Cosmi, B.2    Legnani, C.3
  • 78
    • 77449083472 scopus 로고    scopus 로고
    • Usefulness of repeated D-dimer testing after stopping anticoagulation for a first episode of unprovoked venous thromboembolism: the PROLONG II prospective study
    • PROLONG Investigators (on behalf of Italian Federation of Anticoagulation Clinics).
    • Cosmi B, Legnani C, Tosetto A et al., PROLONG Investigators (on behalf of Italian Federation of Anticoagulation Clinics). Usefulness of repeated D-dimer testing after stopping anticoagulation for a first episode of unprovoked venous thromboembolism: the PROLONG II prospective study. Blood 2010; 115: 481-8.
    • (2010) Blood , vol.115 , pp. 481-488
    • Cosmi, B.1    Legnani, C.2    Tosetto, A.3
  • 80
    • 0031927812 scopus 로고    scopus 로고
    • Control of oral anticoagulation in patients with the antiphospholipid syndrome - influence of the lupus anticoagulant on International Normalized Ratio. Groupe Méthodologie en Hémostase du Groupe d'Etudes sur l'Hémostases et la Thrombose
    • Robert A, Le Querrec A, Delahousse B et al. Control of oral anticoagulation in patients with the antiphospholipid syndrome - influence of the lupus anticoagulant on International Normalized Ratio. Groupe Méthodologie en Hémostase du Groupe d'Etudes sur l'Hémostases et la Thrombose. Thromb Haemost 1998; 80: 99-103.
    • (1998) Thromb Haemost , vol.80 , pp. 99-103
    • Robert, A.1    Le Querrec, A.2    Delahousse, B.3
  • 81
    • 0004750551 scopus 로고    scopus 로고
    • Guidelines on the investigation and management of the antiphospholipid syndrome
    • Greaves M, Cohen H, MacHin SJ, Mackie I. Guidelines on the investigation and management of the antiphospholipid syndrome. Br J Haematol 2000; 109: 704-15.
    • (2000) Br J Haematol , vol.109 , pp. 704-715
    • Greaves, M.1    Cohen, H.2    MacHin, S.J.3    Mackie, I.4
  • 82
    • 10744223871 scopus 로고    scopus 로고
    • Antiphospholipid antibodies and subsequent thrombo-occlusive events in patients with ischemic stroke
    • APASS Investigators.
    • Levine SR, Brey RL, Tilley BC et al., APASS Investigators. Antiphospholipid antibodies and subsequent thrombo-occlusive events in patients with ischemic stroke. JAMA 2004; 291: 576-84.
    • (2004) JAMA , vol.291 , pp. 576-584
    • Levine, S.R.1    Brey, R.L.2    Tilley, B.C.3
  • 83
    • 45949109467 scopus 로고    scopus 로고
    • Antithrombotic and thrombolytic therapy for ischemic stroke: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition)
    • American College of Chest Physicians.
    • Albers GW, Amarenco P, Easton JD, Sacco RL, Teal P, American College of Chest Physicians. Antithrombotic and thrombolytic therapy for ischemic stroke: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest 2008; 133: 630S-69S.
    • (2008) Chest , vol.133
    • Albers, G.W.1    Amarenco, P.2    Easton, J.D.3    Sacco, R.L.4    Teal, P.5
  • 85
    • 0037072090 scopus 로고    scopus 로고
    • Aspirin and coumadin after acute coronary syndromes (the ASPECT-2study): a randomised controlled trial
    • van Es RF, Jonker JJ, Verheugt FW, Deckers JW, Grobbee DE. Aspirin and coumadin after acute coronary syndromes (the ASPECT-2study): a randomised controlled trial. Lancet 2002; 360: 109-13.
    • (2002) Lancet , vol.360 , pp. 109-113
    • van Es, R.F.1    Jonker, J.J.2    Verheugt, F.W.3    Deckers, J.W.4    Grobbee, D.E.5
  • 86
    • 0029934389 scopus 로고    scopus 로고
    • Antiphospholipid antibody-associated recurrent pregnancy loss: treatment with heparin and low-dose aspirin is superior to low-dose aspirin alone
    • Kutteh WH. Antiphospholipid antibody-associated recurrent pregnancy loss: treatment with heparin and low-dose aspirin is superior to low-dose aspirin alone. Am J Obstet Gynecol 1996; 174: 1584-9.
    • (1996) Am J Obstet Gynecol , vol.174 , pp. 1584-1589
    • Kutteh, W.H.1
  • 87
    • 0031022366 scopus 로고    scopus 로고
    • Randomised controlled trial of aspirin and aspirin plus heparin in pregnant women with recurrent miscarriage associated with phospholipid antibodies (or antiphospholipid antibodies)
    • Rai R, Cohen H, Dave M, Regan L. Randomised controlled trial of aspirin and aspirin plus heparin in pregnant women with recurrent miscarriage associated with phospholipid antibodies (or antiphospholipid antibodies). BMJ 1997; 314: 253-7.
    • (1997) BMJ , vol.314 , pp. 253-257
    • Rai, R.1    Cohen, H.2    Dave, M.3    Regan, L.4
  • 88
    • 0036711316 scopus 로고    scopus 로고
    • Antiphospholipid syndrome in pregnancy: a randomized, controlled trial of treatment
    • Farquharson RG, Quenby S, Greaves M. Antiphospholipid syndrome in pregnancy: a randomized, controlled trial of treatment. Obstet Gynecol 2002; 100: 408-13.
    • (2002) Obstet Gynecol , vol.100 , pp. 408-413
    • Farquharson, R.G.1    Quenby, S.2    Greaves, M.3
  • 89
    • 57949106754 scopus 로고    scopus 로고
    • Laboratory classification categories and pregnancy outcome in patients with primary antiphospholipid syndrome prescribed antithrombotic therapy
    • Ruffatti A, Tonello M, Cavazzana A, Bagatella P, Pengo V. Laboratory classification categories and pregnancy outcome in patients with primary antiphospholipid syndrome prescribed antithrombotic therapy. Thromb Res 2009; 123: 482-7.
    • (2009) Thromb Res , vol.123 , pp. 482-487
    • Ruffatti, A.1    Tonello, M.2    Cavazzana, A.3    Bagatella, P.4    Pengo, V.5
  • 90
    • 52449102771 scopus 로고    scopus 로고
    • Influence of different IgG anticardiolipin antibody cut-off values on antiphospholipid syndrome classification
    • Ruffatti A, Olivieri S, Tonello M et al. Influence of different IgG anticardiolipin antibody cut-off values on antiphospholipid syndrome classification. J Thromb Haemost 2008; 6: 1693-6.
    • (2008) J Thromb Haemost , vol.6 , pp. 1693-1696
    • Ruffatti, A.1    Olivieri, S.2    Tonello, M.3
  • 91
    • 0012444692 scopus 로고    scopus 로고
    • Treatment of pregnant patients with antiphospholipid syndrome
    • Tincani A, Branch W, Levy RA et al. Treatment of pregnant patients with antiphospholipid syndrome. Lupus 2003; 12: 524-9.
    • (2003) Lupus , vol.12 , pp. 524-529
    • Tincani, A.1    Branch, W.2    Levy, R.A.3
  • 92
    • 25444463821 scopus 로고    scopus 로고
    • Management of thrombosis in antiphospholipid syndrome and systemic lupus erythematosus in pregnancy
    • Ruiz-Irastorza G, Khamashta MA. Management of thrombosis in antiphospholipid syndrome and systemic lupus erythematosus in pregnancy. Ann N Y Acad Sci 2005; 1051: 606-12.
    • (2005) Ann N Y Acad Sci , vol.1051 , pp. 606-612
    • Ruiz-Irastorza, G.1    Khamashta, M.A.2
  • 93
    • 33748597665 scopus 로고    scopus 로고
    • Antibody profile and clinical course in primary antiphospholipid syndrome with pregnancy morbidity
    • Ruffatti A, Tonello M, Del Ross T et al. Antibody profile and clinical course in primary antiphospholipid syndrome with pregnancy morbidity. Thromb Haemost 2006; 96: 337-41.
    • (2006) Thromb Haemost , vol.96 , pp. 337-341
    • Ruffatti, A.1    Tonello, M.2    Del Ross, T.3
  • 94
    • 77649215763 scopus 로고    scopus 로고
    • Laboratory and clinical features of pregnant women with antiphospholipid syndrome and neonatal outcome
    • Ruffatti A, Calligaro A, Hoxha A et al. Laboratory and clinical features of pregnant women with antiphospholipid syndrome and neonatal outcome. Arthritis Care Res (Hoboken) 2010; 62: 302-7.
    • (2010) Arthritis Care Res (Hoboken) , vol.62 , pp. 302-307
    • Ruffatti, A.1    Calligaro, A.2    Hoxha, A.3
  • 95
    • 33846638644 scopus 로고    scopus 로고
    • Plasma exchange in the management of high risk pregnant patients with primary antiphospholipid syndrome. A report of 9 cases and a review of the literature
    • Ruffatti A, Marson P, Pengo V et al. Plasma exchange in the management of high risk pregnant patients with primary antiphospholipid syndrome. A report of 9 cases and a review of the literature. Autoimmun Rev 2007; 6: 196-202.
    • (2007) Autoimmun Rev , vol.6 , pp. 196-202
    • Ruffatti, A.1    Marson, P.2    Pengo, V.3
  • 96
    • 0036089429 scopus 로고    scopus 로고
    • Catastrophic antiphospholipid syndrome: proposed guidelines for diagnosis and treatment
    • Asherson RA, Espinosa G, Cervera R, Font J, Reverter JC. Catastrophic antiphospholipid syndrome: proposed guidelines for diagnosis and treatment. J Clin Rheumatol 2002; 8: 157-65.
    • (2002) J Clin Rheumatol , vol.8 , pp. 157-165
    • Asherson, R.A.1    Espinosa, G.2    Cervera, R.3    Font, J.4    Reverter, J.C.5
  • 97
    • 0038376616 scopus 로고    scopus 로고
    • Catastrophic antiphospholipid syndrome: international consensus statement on classification criteria and treatment guidelines
    • Asherson RA, Cervera R, de Groot PG et al. Catastrophic antiphospholipid syndrome: international consensus statement on classification criteria and treatment guidelines. Lupus 2003; 12: 530-4.
    • (2003) Lupus , vol.12 , pp. 530-534
    • Asherson, R.A.1    Cervera, R.2    de Groot, P.G.3
  • 98
    • 0346850621 scopus 로고    scopus 로고
    • Catastrophic antiphospholipid syndrome: where do we stand?
    • Erkan D, Cervera R, Asherson RA. Catastrophic antiphospholipid syndrome: where do we stand? Arthritis Rheum 2003; 48: 3320-7.
    • (2003) Arthritis Rheum , vol.48 , pp. 3320-3327
    • Erkan, D.1    Cervera, R.2    Asherson, R.A.3
  • 99
    • 46949086823 scopus 로고    scopus 로고
    • Plasma exchange for the management of the catastrophic antiphospholipid syndrome: importance of the type of fluid replacement
    • Marson P, Bagatella P, Bortolati M et al. Plasma exchange for the management of the catastrophic antiphospholipid syndrome: importance of the type of fluid replacement. J Intern Med 2008; 264: 201-3.
    • (2008) J Intern Med , vol.264 , pp. 201-203
    • Marson, P.1    Bagatella, P.2    Bortolati, M.3
  • 100
    • 61349196388 scopus 로고    scopus 로고
    • Recovery from catastrophic antiphospholipid syndrome by a plasma exchange procedure: report of four cases and review of the literature
    • Bortolati M, Marson P, Fabris F et al. Recovery from catastrophic antiphospholipid syndrome by a plasma exchange procedure: report of four cases and review of the literature. Autoimmun Rev 2009; 8: 297-301.
    • (2009) Autoimmun Rev , vol.8 , pp. 297-301
    • Bortolati, M.1    Marson, P.2    Fabris, F.3
  • 101
    • 77249103016 scopus 로고    scopus 로고
    • Use of rituximab in the antiphospholipid syndrome
    • Kumar D, Roubey RA. Use of rituximab in the antiphospholipid syndrome. Curr Rheumatol Rep 2010; 12: 40-4.
    • (2010) Curr Rheumatol Rep , vol.12 , pp. 40-44
    • Kumar, D.1    Roubey, R.A.2
  • 102
    • 34548038654 scopus 로고    scopus 로고
    • Clinical significance of different antiphospholipid antibodies in the WAPS (warfarin in the antiphospholipid syndrome) study
    • Galli M, Borrelli G, Jacobsen EM et al. Clinical significance of different antiphospholipid antibodies in the WAPS (warfarin in the antiphospholipid syndrome) study. Blood 2007; 110: 1178-83.
    • (2007) Blood , vol.110 , pp. 1178-1183
    • Galli, M.1    Borrelli, G.2    Jacobsen, E.M.3
  • 103
    • 70449390005 scopus 로고    scopus 로고
    • The association between circulating antibodies against domain I of beta2-glycoprotein I and thrombosis: an international multicenter study
    • de Laat B, Pengo V, Pabinger I et al. The association between circulating antibodies against domain I of beta2-glycoprotein I and thrombosis: an international multicenter study. J Thromb Haemost 2009; 7: 1767-73.
    • (2009) J Thromb Haemost , vol.7 , pp. 1767-1773
    • de Laat, B.1    Pengo, V.2    Pabinger, I.3
  • 104
    • 78650963444 scopus 로고    scopus 로고
    • An international multicentre-laboratory evaluation of a new assay to detect specifically lupus anticoagulants dependent on the presence of anti-beta2-glycoprotein autoantibodies
    • de Laat B, Derksen RH, Reber G et al. An international multicentre-laboratory evaluation of a new assay to detect specifically lupus anticoagulants dependent on the presence of anti-beta2-glycoprotein autoantibodies. J Thromb Haemost 2011; 9: 149-153.
    • (2011) J Thromb Haemost , vol.9 , pp. 149-153
    • de Laat, B.1    Derksen, R.H.2    Reber, G.3
  • 105
    • 0032588145 scopus 로고    scopus 로고
    • Do antibodies to beta2-glycoprotein 1 contribute to the better characterization of the antiphospholipid syndrome?
    • Detkov PY, Gil-Aguado A, Lavilla P, Cuesta MV, Fontán G, Pascual-Salcedo D. Do antibodies to beta2-glycoprotein 1 contribute to the better characterization of the antiphospholipid syndrome? Lupus 1999; 8: 430-8.
    • (1999) Lupus , vol.8 , pp. 430-438
    • Detkov, P.Y.1    Gil-Aguado, A.2    Lavilla, P.3    Cuesta, M.V.4    Fontán, G.5    Pascual-Salcedo, D.6
  • 106
    • 0344440948 scopus 로고    scopus 로고
    • Does the anti-beta2-glycoprotein I antibody provide additional information in patients with thrombosis?
    • Lee EY, Lee CK, Lee TH et al. Does the anti-beta2-glycoprotein I antibody provide additional information in patients with thrombosis? Thromb Res 2003; 111: 29-32.
    • (2003) Thromb Res , vol.111 , pp. 29-32
    • Lee, E.Y.1    Lee, C.K.2    Lee, T.H.3
  • 107
    • 33646462158 scopus 로고    scopus 로고
    • Anti-beta2-glycoprotein I antibodies are associated with pregnancy loss in women with the lupus anticoagulant
    • Sailer T, Zoghlami C, Kurz C et al. Anti-beta2-glycoprotein I antibodies are associated with pregnancy loss in women with the lupus anticoagulant. Thromb Haemost 2006; 95: 796-801.
    • (2006) Thromb Haemost , vol.95 , pp. 796-801
    • Sailer, T.1    Zoghlami, C.2    Kurz, C.3
  • 108
    • 24944564772 scopus 로고    scopus 로고
    • The presence of IgG antibodies against beta2-glycoprotein I predicts the risk of thrombosis in patients with the lupus anticoagulant
    • Zoghlami-Rintelen C, Vormittag R, Sailer T et al. The presence of IgG antibodies against beta2-glycoprotein I predicts the risk of thrombosis in patients with the lupus anticoagulant. J Thromb Haemost 2005; 3: 1160-5.
    • (2005) J Thromb Haemost , vol.3 , pp. 1160-1165
    • Zoghlami-Rintelen, C.1    Vormittag, R.2    Sailer, T.3
  • 110
    • 34548816709 scopus 로고    scopus 로고
    • beta2-Glycoprotein I inhibits von Willebrand factor dependent platelet adhesion and aggregation
    • Hulstein JJ, Lenting PJ, de Laat B, Derksen RH, Fijnheer R, de Groot PG. beta2-Glycoprotein I inhibits von Willebrand factor dependent platelet adhesion and aggregation. Blood 2007; 110: 1483-91.
    • (2007) Blood , vol.110 , pp. 1483-1491
    • Hulstein, J.J.1    Lenting, P.J.2    de Laat, B.3    Derksen, R.H.4    Fijnheer, R.5    de Groot, P.G.6
  • 111
    • 45549094816 scopus 로고    scopus 로고
    • Beta2-glycoprotein I inhibits vascular endothelial growth factor and basic fibroblast growth factor induced angiogenesis through its amino terminal domain
    • Yu P, Passam FH, Yu DM, Denyer G, Krilis SA. Beta2-glycoprotein I inhibits vascular endothelial growth factor and basic fibroblast growth factor induced angiogenesis through its amino terminal domain. J Thromb Haemost 2008; 6: 1215-23.
    • (2008) J Thromb Haemost , vol.6 , pp. 1215-1223
    • Yu, P.1    Passam, F.H.2    Yu, D.M.3    Denyer, G.4    Krilis, S.A.5
  • 112
    • 67349109452 scopus 로고    scopus 로고
    • The immunology of atherothrombosis in the antiphospholipid syndrome: antigen presentation and lipid intracellular accumulation
    • Matsuura E, Kobayashi K, Matsunami Y, Lopez LR. The immunology of atherothrombosis in the antiphospholipid syndrome: antigen presentation and lipid intracellular accumulation. Autoimmun Rev 2009; 8: 500-5.
    • (2009) Autoimmun Rev , vol.8 , pp. 500-505
    • Matsuura, E.1    Kobayashi, K.2    Matsunami, Y.3    Lopez, L.R.4


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