Non-adherence to aspirin in patients undergoing coronary stenting: Negative impact of comorbid conditions and implications for clinical management

Archives of Cardiovascular Diseases

Volumn 104, Issue 5, 2011, Pages 306-312

  Cuisset, Thomas ^a   Quilici, Jacques ^a   Fugon, Lionel ^c,d,e   Cohen, William ^b   Roux, Perrine ^c,d,e   Gaborit, Bénédicte ^b   Molines, Laurent ^b   Fourcade, Laurent ^f   Bonnet, Jean Louis ^a   Carrieri, Patrizia ^c,d,e  

^a TIMONE HOSPITAL   (France)

^b INSERM   (France)

^c AIX MARSEILLE UNIV   (France)

^d AIX MARSEILLE UNIVERSITY   (France)

^e OBSERVATOIRE RÉGIONAL DE LA SANTÉ PROVENCE ALPES CÔTE D AZUR   (France)

^f LAVERAN MILITARY TEACHING HOSPITAL   (France)

Author keywords

Aspirin; Compliance; Coronary stenting; Non adherence

Indexed keywords

ACETYLSALICYLIC ACID; CLOPIDOGREL;

ACUTE CORONARY SYNDROME; ADULT; ARTICLE; BLOOD CLOTTING PARAMETERS; CARDIAC PATIENT; COMORBIDITY; CORONARY STENT; DIABETES MELLITUS; FEMALE; HIGH RISK POPULATION; HOSPITAL DISCHARGE; HUMAN; LONG TERM CARE; MAJOR CLINICAL STUDY; MALE; NON ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; PATIENT ASSESSMENT; SMOKING; THROMBOCYTE AGGREGATION; TREATMENT RESPONSE;

AGED; ANGIOPLASTY, BALLOON, CORONARY; ASPIRIN; COMORBIDITY; CORONARY ARTERY DISEASE; FEMALE; FRANCE; HUMANS; LOGISTIC MODELS; MALE; MEDICATION ADHERENCE; MIDDLE AGED; ODDS RATIO; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; PLATELET FUNCTION TESTS; PROSPECTIVE STUDIES; RISK ASSESSMENT; RISK FACTORS; STENTS; THROMBOSIS; TIME FACTORS; TREATMENT OUTCOME;

EID: 79959374188     PISSN: 18752136     EISSN: 18752128     Source Type: Journal    
DOI: 10.1016/j.acvd.2011.03.091     Document Type: Article

References (21)

1. S.R. Mehta, S. Yusuf, and R.J. Peters Effects of pretreatment with clopidogrel and aspirin followed by long-term therapy in patients undergoing percutaneous coronary intervention: the PCI-CURE study Lancet 358 2001 527 533 (Pubitemid 32772726)
2. S. Yusuf, F. Zhao, and S.R. Mehta Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation N Engl J Med 345 2001 494 502 (Pubitemid 32758501)
3. S. Sanderson, J. Emery, and T. Baglin Narrative review: aspirin resistance and its clinical implications Ann Intern Med 142 2005 370 380 (Pubitemid 40293410)
4. W.H. Chen, P.Y. Lee, and W. Ng Aspirin resistance is associated with a high incidence of myonecrosis after non-urgent percutaneous coronary intervention despite clopidogrel pretreatment J Am Coll Cardiol 43 2004 1122 1126 (Pubitemid 38353000)
5. T. Cuisset, C. Frere, and J. Quilici High post-treatment platelet reactivity identified low-responders to dual antiplatelet therapy at increased risk of recurrent cardiovascular events after stenting for acute coronary syndrome J Thromb Haemost 4 2006 542 549
6. J.W. Eikelboom, J. Hirsh, and J.I. Weitz Aspirin-resistant thromboxane biosynthesis and the risk of myocardial infarction, stroke, or cardiovascular death in patients at high risk for cardiovascular events Circulation 105 2002 1650 1655 (Pubitemid 34298607)
7. A.M. Gori, R. Marcucci, and A. Migliorini Incidence and clinical impact of dual nonresponsiveness to aspirin and clopidogrel in patients with drug-eluting stents J Am Coll Cardiol 52 2008 734 739
8. P.A. Gum, K. Kottke-Marchant, and P.A. Welsh A prospective, blinded determination of the natural history of aspirin resistance among stable patients with cardiovascular disease J Am Coll Cardiol 41 2003 961 965 (Pubitemid 36315537)
9. T. Cuisset, C. Frere, and J. Quilici Aspirin noncompliance is the major cause of "aspirin resistance" in patients undergoing coronary stenting Am Heart J 157 2009 889 893
10. D.W. Hosmer, and S. Lemeshow Applied Logistic Regression 2nd ed 2000 Wiley New York
11. E.J. Gallagher, C.M. Viscoli, and R.I. Horwitz The relationship of treatment adherence to the risk of death after myocardial infarction in women JAMA 270 1993 742 744 (Pubitemid 23226634)
12. R.I. Horwitz, C.M. Viscoli, and L. Berkman Treatment adherence and risk of death after a myocardial infarction Lancet 336 1990 542 545 (Pubitemid 20278106)
13. I. Iakovou, T. Schmidt, and E. Bonizzoni Incidence, predictors, and outcome of thrombosis after successful implantation of drug-eluting stents JAMA 293 2005 2126 2130 (Pubitemid 40617065)
14. C.A. Jackevicius, P. Li, and J.V. Tu Prevalence, predictors, and outcomes of primary nonadherence after acute myocardial infarction Circulation 117 2008 1028 1036
15. J.A. Spertus, R. Kettelkamp, and C. Vance Prevalence, predictors, and outcomes of premature discontinuation of thienopyridine therapy after drug-eluting stent placement: results from the PREMIER registry Circulation 113 2006 2803 2809 (Pubitemid 44305292)
16. M. Byrne, J. Walsh, and A.W. Murphy Secondary prevention of coronary heart disease: patient beliefs and health-related behaviour J Psychosom Res 58 2005 403 415 (Pubitemid 40982202)
17. P. Roy, L. Bonello, and R. Torguson Impact of "nuisance" bleeding on clopidogrel compliance in patients undergoing intracoronary drug-eluting stent implantation Am J Cardiol 102 2008 1614 1617
18. G. Krasopoulos, S.J. Brister, and W.S. Beattie Aspirin "resistance" and risk of cardiovascular morbidity: systematic review and meta-analysis BMJ 336 2008 195 198 (Pubitemid 351212675)
19. A. Jerant, R. DiMatteo, and J. Arnsten Self-report adherence measures in chronic illness: retest reliability and predictive validity Med Care 46 2008 1134 1139
20. P.T. Nieuwkerk, and F.J. Oort Self-reported adherence to antiretroviral therapy for HIV-1 infection and virologic treatment response: a meta-analysis J Acquir Immune Defic Syndr 38 2005 445 448 (Pubitemid 40381555)
21. P. Tuppin, A. Neumann, and N. Danchin Evidence-based pharmacotherapy after myocardial infarction in France: adherence-associated factors and relationship with 30-month mortality and rehospitalization Arch Cardiovasc Dis 103 2010 363 375