메뉴 건너뛰기




Volumn 10, Issue 27, 2011, Pages 5370-5376

Norcantharidin (NCTD) induces mitochondria mediated apoptosis in human HepG2 cells

Author keywords

Apoptosis; Bax Bcl 2; Caspase; Cyto C; HepG2 cells; Norcantharidin

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CASPASE 3; CASPASE 9; CYTOCHROME C; NORCANTHARIDIN; PROTEIN BAX; PROTEIN BCL 2;

EID: 79959348366     PISSN: 16845315     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (2)

References (23)
  • 1
    • 75649091175 scopus 로고    scopus 로고
    • Resveratrol induces apoptosis and cell cycle arrest of human T24 bladder cancer cells in vitro and inhibits tumor growth in vivo
    • Bai Y, Mao QQ, Qin J, Zheng XY, Wang YB (2010). Resveratrol induces apoptosis and cell cycle arrest of human T24 bladder cancer cells in vitro and inhibits tumor growth in vivo. Cancer. Sci. 101(2): 488-493.
    • (2010) Cancer. Sci , vol.101 , Issue.2 , pp. 488-493
    • Bai, Y.1    Mao, Q.Q.2    Qin, J.3    Zheng, X.Y.4    Wang, Y.B.5
  • 2
    • 66449121454 scopus 로고    scopus 로고
    • Regulation of mitochondrial dynamics in acute kidney injury in cell culture and rodent models
    • Brooks C, Wei Q, Cho SG (2009). Regulation of mitochondrial dynamics in acute kidney injury in cell culture and rodent models. J. Clin. Invest. 119: 1275-1285
    • (2009) J. Clin. Invest , vol.119 , pp. 1275-1285
    • Brooks, C.1    Wei, Q.2    Cho, S.G.3
  • 3
    • 0037054929 scopus 로고    scopus 로고
    • Effector mechanisms of norcantharidin induced mitotic arrest and apoptosis in human hepatoma cells
    • Chen YN, Chen JC, Yin SC (2002). Effector mechanisms of norcantharidin induced mitotic arrest and apoptosis in human hepatoma cells. Int. J Cancer. 100: 158-165.
    • (2002) Int. J Cancer , vol.100 , pp. 158-165
    • Chen, Y.N.1    Chen, J.C.2    Yin, S.C.3
  • 4
    • 0027374638 scopus 로고
    • A new method for the cytofluorimetric analysis of mitochondrial membrane potential using the J-aggregate forming lipophilic cation 5,5',6,6'-tetrachloro-1,1',3,3'-tetraethylbenzimidazolcarbocyanine iodide (JC-1)
    • Cossarizza A, Baccarani-Contri M, Kalashnikova G, Franceschi C (1993). A new method for the cytofluorimetric analysis of mitochondrial membrane potential using the J-aggregate forming lipophilic cation 5,5',6,6'-tetrachloro-1,1',3,3'-tetraethylbenzimidazolcarbocyanine iodide (JC-1). Biochem. Biophys. Res. Commun. 197(1): 40-45.
    • (1993) Biochem. Biophys. Res. Commun , vol.197 , Issue.1 , pp. 40-45
    • Cossarizza, A.1    Baccarani-Contri, M.2    Kalashnikova, G.3    Franceschi, C.4
  • 5
    • 44949219131 scopus 로고    scopus 로고
    • A review on plant-derived natural products and their analogs with anti-tumor activity
    • Dholwani KK, Saluja AK, Gupta AR, Shah DR (2008). A review on plant-derived natural products and their analogs with anti-tumor activity. Indian. J. Pharmacol. 40(2): 49-58.
    • (2008) Indian. J. Pharmacol , vol.40 , Issue.2 , pp. 49-58
    • Dholwani, K.K.1    Saluja, A.K.2    Gupta, A.R.3    Shah, D.R.4
  • 6
    • 0034675351 scopus 로고    scopus 로고
    • Norcantharidin-induced post-G(2)/M apoptosis is dependent on wild-type p53 gene
    • Hong CY, Huang SC, Lin SK (2000). Norcantharidin-induced post-G(2)/M apoptosis is dependent on wild-type p53 gene. Biochem. Biophys. Res Commun. 276: 278-285.
    • (2000) Biochem. Biophys. Res Commun , vol.276 , pp. 278-285
    • Hong, C.Y.1    Huang, S.C.2    Lin, S.K.3
  • 7
    • 79952327221 scopus 로고    scopus 로고
    • Cantharidin induces G2/M phase arrest and apoptosis in human colorectal cancer colo 205 cells through inhibition of CDK1 activity and caspase-dependent signaling pathways
    • Huang WW, Ko SW, Tsai HY, Chung JG, Chiang JH, Chen KT (2011). Cantharidin induces G2/M phase arrest and apoptosis in human colorectal cancer colo 205 cells through inhibition of CDK1 activity and caspase-dependent signaling pathways. Int. J. Oncol. 38(4): 1067-1073.
    • (2011) Int. J. Oncol , vol.38 , Issue.4 , pp. 1067-1073
    • Huang, W.W.1    Ko, S.W.2    Tsai, H.Y.3    Chung, J.G.4    Chiang, J.H.5    Chen, K.T.6
  • 8
    • 77955635233 scopus 로고    scopus 로고
    • Cancer statistics, 2010. CA Cancer. J. Clin
    • Jemal A, Siegel R, Xu J, Ward E (2010). Cancer statistics, 2010. CA Cancer. J. Clin. 60(5): 277-300.
    • (2010) , vol.60 , Issue.5 , pp. 277-300
    • Jemal, A.1    Siegel, R.2    Xu, J.3    Ward, E.4
  • 10
    • 10444235120 scopus 로고    scopus 로고
    • Norcantharidin-induced apoptosis in oral cancer cells is associated with an increase of proapoptotic to antiapoptotic protein ratio
    • Kok SH, Cheng SJ, Hong CY, Lee JJ, Lin SK, Kuo YS (2005). Norcantharidin-induced apoptosis in oral cancer cells is associated with an increase of proapoptotic to antiapoptotic protein ratio. Cancer. Lett. 217(1):43-52.
    • (2005) Cancer. Lett , vol.217 , Issue.1 , pp. 43-52
    • Kok, S.H.1    Cheng, S.J.2    Hong, C.Y.3    Lee, J.J.4    Lin, S.K.5    Kuo, Y.S.6
  • 11
    • 77957873171 scopus 로고    scopus 로고
    • Cantharidin induces apoptosis in human bladder cancer TSGH 8301 cells through mitochondria-dependent signal pathways
    • Kuo JH, Chu YL, Yang JS, Lin JP, Lai KC (2010). Cantharidin induces apoptosis in human bladder cancer TSGH 8301 cells through mitochondria-dependent signal pathways. Int. J. Oncol. 37(5): 1243-1250.
    • (2010) Int. J. Oncol , vol.37 , Issue.5 , pp. 1243-1250
    • Kuo, J.H.1    Chu, Y.L.2    Yang, J.S.3    Lin, J.P.4    Lai, K.C.5
  • 12
    • 77953712167 scopus 로고    scopus 로고
    • Mitochondrial signaling in cell death via the Bcl-2 family
    • Leibowitz B, Yu J (2010). Mitochondrial signaling in cell death via the Bcl-2 family. Cancer. Biol. Ther. 9: 417-422.
    • (2010) Cancer biol ther , vol.9 , pp. 417-422
    • Leibowitz, B.1    Yu, J.2
  • 13
    • 77951737265 scopus 로고    scopus 로고
    • Chemoinformatics approaches for traditional Chinese medicine research and case application in anticancer drug discovery
    • Li XJ, Kong DX, Zhang HY (2010). Chemoinformatics approaches for traditional Chinese medicine research and case application in anticancer drug discovery. Curr. Drug. Discov. Technol. 7(1): 22-31.
    • (2010) Curr. Drug. Discov. Technol , vol.7 , Issue.1 , pp. 22-31
    • Li, X.J.1    Kong, D.X.2    Zhang, H.Y.3
  • 14
    • 77954669821 scopus 로고    scopus 로고
    • Tian Xian Liquid (TXL) induces apoptosis in HT-29 colon cancer cell in vitro and inhibits tumor growth in vivo
    • Liu Q, Tong Y, Sze SC, Liu WK, Lam L, Chu ES, Yow CM (2010). Tian Xian Liquid (TXL) induces apoptosis in HT-29 colon cancer cell in vitro and inhibits tumor growth in vivo. Chin. Med. 5: 25.
    • (2010) Chin Med , vol.5 , pp. 25
    • Liu, Q.1    Tong, Y.2    Sze, S.C.3    Liu, W.K.4    Lam, L.5    Chu, E.S.6    Yow, C.M.7
  • 15
    • 0029850794 scopus 로고    scopus 로고
    • Efficacy of intra-arterial norcantharidin in suppressing tumour 14C-labelled glucose oxidative metabolism in rat Morris hepatoma
    • Mack P, Ha XF, Cheng LY (1996). Efficacy of intra-arterial norcantharidin in suppressing tumour 14C-labelled glucose oxidative metabolism in rat Morris hepatoma. HPB. Surg. 10: 65-72.
    • (1996) Hpb Surg , vol.10 , pp. 65-72
    • Mack, P.1    Ha, X.F.2    Cheng, L.Y.3
  • 16
    • 45449083640 scopus 로고    scopus 로고
    • Living with death: The evolution of the mitochondrial pathway of apoptosis in animals
    • Oberst A, Bender C, Green DR (2008). Living with death: the evolution of the mitochondrial pathway of apoptosis in animals. Cell. Death. Differ. 15: 1139-1146.
    • (2008) Cell. Death Differ , vol.15 , pp. 1139-1146
    • Oberst, A.1    Bender, C.2    Green, D.R.3
  • 17
    • 0036204047 scopus 로고    scopus 로고
    • Induction of apoptosis by norcantharidin in human colorectal carcinoma cell lines: Involvement of the CD95 receptor/ligand
    • Peng F, Wei YQ, Tian L, Yang L, Zhao X (2002). Induction of apoptosis by norcantharidin in human colorectal carcinoma cell lines: involvement of the CD95 receptor/ligand. J. Cancer. Res. Clin. Oncol. 128: 223-230.
    • (2002) J. Cancer. Res. Clin. Oncol , vol.128 , pp. 223-230
    • Peng, F.1    Wei, Y.Q.2    Tian, L.3    Yang, L.4    Zhao, X.5
  • 18
    • 68949141833 scopus 로고    scopus 로고
    • Opening the doors to cytochrome c: Changes in mitochondrial shape and apoptosis
    • Scorrano L (2009). Opening the doors to cytochrome c: Changes in mitochondrial shape and apoptosis. Int. J. Biochem. Cell. Biol. 41: 1875-1883.
    • (2009) Int. J. Biochem. Cell. Biol , vol.41 , pp. 1875-1883
    • Scorrano, L.1
  • 20
    • 0024428817 scopus 로고
    • Medical uses of mylabris in ancient China and recent studies
    • Wang GS (1989). Medical uses of mylabris in ancient China and recent studies. J. Ethnopharmacol. 26: 147-162.
    • (1989) J. Ethnopharmacol , vol.26 , pp. 147-162
    • Wang, G.S.1
  • 21
    • 77949888700 scopus 로고    scopus 로고
    • Structure, Function and Inhibition of Bcl-2 Family Proteins:A New Target for Anti-Tumor Agents
    • Xiao G, Fang H, Xing C (2009). Structure, Function and Inhibition of Bcl-2 Family Proteins:A New Target for Anti-Tumor Agents. Mini. Rev. Med. Chem. 9: 1596-1604.
    • (2009) Mini Rev. Med. Chem , vol.9 , pp. 1596-1604
    • Xiao, G.1    Fang, H.2    Xing, C.3
  • 22
    • 77956184488 scopus 로고    scopus 로고
    • Anti-proliferative effect of Juglone from Juglans mandshurica Maxim on human leukemia cell HL-60 by inducing apoptosis through the mitochondria-dependent pathway
    • Xu HL, Yu XF, Qu SC, Zhang R, Qu XR, Sui DY (2010). Anti-proliferative effect of Juglone from Juglans mandshurica Maxim on human leukemia cell HL-60 by inducing apoptosis through the mitochondria-dependent pathway. Eur. J. Pharmacol. 645: 14-22.
    • (2010) Eur. J. Pharmacol , vol.645 , pp. 14-22
    • Xu, H.L.1    Yu, X.F.2    Qu, S.C.3    Zhang, R.4    Qu, X.R.5    Sui, D.Y.6
  • 23
    • 78149412422 scopus 로고    scopus 로고
    • A synthetic cantharidin analog for the enhancement of doxorubicin suppression of stem cell-derived aggressive sarcoma
    • Zhang C, Peng Y, Wang F, Tan X, Liu N, Fan S (2010). A synthetic cantharidin analog for the enhancement of doxorubicin suppression of stem cell-derived aggressive sarcoma. Biomaterials. 31(36): 9535-9543.
    • (2010) Biomaterials , vol.31 , Issue.36 , pp. 9535-9543
    • Zhang, C.1    Peng, Y.2    Wang, F.3    Tan, X.4    Liu, N.5    Fan, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.