The mammalian Sin3 proteins are required for muscle development and sarcomere specification

Molecular and Cellular Biology

Volumn 30, Issue 24, 2010, Pages 5686-5697

  Van Oevelen, Chris ^a   Bowman, Christopher ^a   Pellegrino, Jessica ^a   Asp, Patrik ^a   Cheng, Jemmie ^a   Parisi, Fabio ^a   Micsinai, Mariann ^a   Kluger, Yuval ^a   Chu, Alphonse ^b   Blais, Alexandre ^b   David, Gregory ^a   Dynlacht, Brian D ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF OTTAWA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ISOPROTEIN; REPRESSOR PROTEIN; SIN3A TRANSCRIPTION FACTOR; SIN3B PROTEIN, MOUSE;

ANIMAL; ARTICLE; CELL LINE; CYTOLOGY; GENE DELETION; GENETICS; METABOLISM; MOUSE; MUSCLE DEVELOPMENT; PHENOTYPE; PHYSIOLOGY; RNA INTERFERENCE; SARCOMERE; SKELETAL MUSCLE; SURVIVAL RATE; ULTRASTRUCTURE;

ANIMALS; CELL LINE; GENE DELETION; MICE; MUSCLE DEVELOPMENT; MUSCLE, SKELETAL; PHENOTYPE; PROTEIN ISOFORMS; REPRESSOR PROTEINS; RNA INTERFERENCE; SARCOMERES; SURVIVAL RATE;

EID: 79959345514     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.00975-10     Document Type: Article

References (41)

1. Alland, L., R. Muhle, H. Hou, Jr., J. Potes, L. Chin, N. Schreiber-Agus, and R. A. DePinho. 1997. Role for N-CoR and histone deacetylase in Sin3- mediated transcriptional repression. Nature 387:49-55.
2. Ayer, D. E., Q. A. Lawrence, and R. N. Eisenman. 1995. Mad-Max transcriptional repression is mediated by ternary complex formation with mammalian homologs of yeast repressor Sin3. Cell 80:767-776.
3. Batchelor, C. L., and S. J. Winder. 2006. Sparks, signals and shock absorbers: how dystrophin loss causes muscular dystrophy. Trends Cell Biol. 16:198- 205.
4. Blais, A., M. Tsikitis, D. Acosta-Alvear, R. Sharan, Y. Kluger, and B. D. Dynlacht. 2005. An initial blueprint for myogenic differentiation. Genes Dev. 19:553-569.
5. Blais, A., C. J. van Oevelen, R. Margueron, D. Acosta-Alvear, and B. D. Dynlacht. 2007. Retinoblastoma tumor suppressor protein-dependent meth- ylation of histone H3 lysine 27 is associated with irreversible cell cycle exit. J. Cell Biol. 179:1399-1412.
6. Bruning, J. C., M. D. Michael, J. N. Winnay, T. Hayashi, D. Horsch, D. Accili, L. J. Goodyear, and C. R. Kahn. 1998. A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance. Mol. Cell 2:559-569.
7. Burkin, D. J., and S. J. Kaufman. 1999. The alpha7beta1 integrin in muscle development and disease. Cell Tissue Res. 296:183-190.
8. Carrozza, M. J., B. Li, L. Florens, T. Suganuma, S. K. Swanson, K. K. Lee, W. J. Shia, S. Anderson, J. Yates, M. P. Washburn, and J. L. Workman. 2005. Histone H3 methylation by Set2 directs deacetylation of coding regions by Rpd3S to suppress spurious intragenic transcription. Cell 123:581-592.
9. Cavellan, E., P. Asp, P. Percipalle, and A. K. Farrants. 2006. The WSTFSNF2h chromatin remodeling complex interacts with several nuclear proteins in transcription. J. Biol. Chem. 281:16264-16271.
10. Cowley, S. M., B. M. Iritani, S. M. Mendrysa, T. Xu, P. F. Cheng, J. Yada, H. D. Liggitt, and R. N. Eisenman. 2005. The mSin3A chromatin-modifying complex is essential for embryogenesis and T-cell development. Mol. Cell. Biol. 25:6990-7004.
11. Cunliffe, V. T. 2008. Eloquent silence: developmental functions of Class I histone deacetylases. Curr. Opin. Genet. Dev. 18:404-410.
12. Dannenberg, J. H., G. David, S. Zhong, J. van der Torre, W. H. Wong, and R. A. Depinho. 2005. mSin3A corepressor regulates diverse transcriptional networks governing normal and neoplastic growth and survival. Genes Dev. 19:1581-1595.
13. David, G., K. B. Grandinetti, P. M. Finnerty, N. Simpson, G. C. Chu, and R. A. Depinho. 2008. Specific requirement of the chromatin modifier mSin3B in cell cycle exit and cellular differentiation. Proc. Natl. Acad. Sci. U. S. A. 105:4168-4172.
14. Dennis, G., Jr., B. T. Sherman, D. A. Hosack, J. Yang, W. Gao, H. C. Lane, and R. A. Lempicki. 2003. DAVID: Database for Annotation, Visualization, and Integrated Discovery. Genome Biol. 4:P3.
15. Heinzel, T., R. M. Lavinsky, T. M. Mullen, M. Soderstrom, C. D. Laherty, J. Torchia, W. M. Yang, G. Brard, S. D. Ngo, J. R. Davie, E. Seto, R. N. Eisenman, D. W. Rose, C. K. Glass, and M. G. Rosenfeld. 1997. A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression. Nature 387:43-48.
16. Huh, M. S., M. H. Parker, A. Scime, R. Parks, and M. A. Rudnicki. 2004. Rb is required for progression through myogenic differentiation but not maintenance of terminal differentiation. J. Cell Biol. 166:865-876.
17. Kadosh, D., and K. Struhl. 1997. Repression by Ume6 involves recruitment of a complex containing Sin3 corepressor and Rpd3 histone deacetylase to target promoters. Cell 89:365-371.
18. Keogh, M. C., S. K. Kurdistani, S. A. Morris, S. H. Ahn, V. Podolny, S. R. Collins, M. Schuldiner, K. Chin, T. Punna, N. J. Thompson, C. Boone, A. Emili, J. S. Weissman, T. R. Hughes, B. D. Strahl, M. Grunstein, J. F. Greenblatt, S. Buratowski, and N. J. Krogan. 2005. Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex. Cell 123:593-605.
19. Kurdistani, S. K., D. Robyr, S. Tavazoie, and M. Grunstein. 2002. Genomewide binding map of the histone deacetylase Rpd3 in yeast. Nat. Genet. 31:248-254.
20. Laherty, C. D., W. M. Yang, J. M. Sun, J. R. Davie, E. Seto, and R. N. Eisenman. 1997. Histone deacetylases associated with the mSin3 corepressor mediate mad transcriptional repression. Cell 89:349-356.
21. Laing, N. G., and K. J. Nowak. 2005. When contractile proteins go bad: the sarcomere and skeletal muscle disease. Bioessays 27:809-822.
22. Lee, J. S., and A. Shilatifard. 2007. A site to remember: H3K36 methylation a mark for histone deacetylation. Mutat. Res. 618:130-134.
23. Lee, N., H. Erdjument-Bromage, P. Tempst, R. S. Jones, and Y. Zhang. 2009. The H3K4 demethylase lid associates with and inhibits histone deacetylase Rpd3. Mol. Cell. Biol. 29:1401-1410.
24. Li, B., M. Carey, and J. L. Workman. 2007. The role of chromatin during transcription. Cell 128:707-719.
25. McDonel, P., I. Costello, and B. Hendrich. 2009. Keeping things quiet: roles of NuRD and Sin3 co-repressor complexes during mammalian development. Int. J. Biochem. Cell Biol. 41:108-116.
26. McNally, E. M., and P. Pytel. 2007. Muscle diseases: the muscular dystrophies. Annu. Rev. Pathol. 2:87-109.
27. Nicolas, E., T. Yamada, H. P. Cam, P. C. Fitzgerald, R. Kobayashi, and S. I. Grewal. 2007. Distinct roles of HDAC complexes in promoter silencing, antisense suppression and DNA damage protection. Nat. Struct. Mol. Biol. 14:372-380.
28. Pile, L. A., P. T. Spellman, R. J. Katzenberger, and D. A. Wassarman. 2003. The SIN3 deacetylase complex represses genes encoding mitochondrial proteins: implications for the regulation of energy metabolism. J. Biol. Chem. 278:37840-37848.
29. Rando, T. A., and H. M. Blau. 1994. Primary mouse myoblast purification, characterization, and transplantation for cell-mediated gene therapy. J. Cell Biol. 125:1275-1287.
30. Rayman, J. B., Y. Takahashi, V. B. Indjeian, J. H. Dannenberg, S. Catchpole, R. J. Watson, H. te Riele, and B. D. Dynlacht. 2002. E2F mediates cell cycle-dependent transcriptional repression in vivo by recruitment of an HDAC1/mSin3B corepressor complex. Genes Dev. 16:933-947.
31. Robert, F., D. K. Pokholok, N. M. Hannett, N. J. Rinaldi, M. Chandy, A. Rolfe, J. L. Workman, D. K. Gifford, and R. A. Young. 2004. Global position and recruitment of HATs and HDACs in the yeast genome. Mol. Cell 16:199-209.
32. Schreiber-Agus, N., L. Chin, K. Chen, R. Torres, G. Rao, P. Guida, A. I. Skoultchi, and R. A. DePinho. 1995. An amino-terminal domain of Mxi1 mediates anti-Myc oncogenic activity and interacts with a homolog of the yeast transcriptional repressor SIN3. Cell 80:777-786.
33. Schwander, M., M. Leu, M. Stumm, O. M. Dorchies, U. T. Ruegg, J. Schittny, and U. Muller. 2003. Beta1 integrins regulate myoblast fusion and sarcomere assembly. Dev. Cell 4:673-685.
34. Secombe, J., L. Li, L. Carlos, and R. N. Eisenman. 2007. The Trithorax group protein Lid is a trimethyl histone H3K4 demethylase required for dMyc-induced cell growth. Genes Dev. 21:537-551.
35. Sharma, V., A. Swaminathan, R. Bao, and L. A. Pile. 2008. Drosophila SIN3 is required at multiple stages of development. Dev. Dyn. 237:3040-3050.
36. Silverstein, R. A., and K. Ekwall. 2005. Sin3: a flexible regulator of global gene expression and genome stability. Curr. Genet. 47:1-17.
37. Takahashi, Y., J. B. Rayman, and B. D. Dynlacht. 2000. Analysis of promoter binding by the E2F and pRB families in vivo: distinct E2F proteins mediate activation and repression. Genes Dev. 14:804-816.
38. Tallquist, M. D., K. E. Weismann, M. Hellstrom, and P. Soriano. 2000. Early myotome specification regulates PDGFA expression and axial skeleton development. Development 127:5059-5070.
39. van Oevelen, C., J. Wang, P. Asp, Q. Yan, W. G. Kaelin, Jr., Y. Kluger, and B. D. Dynlacht. 2008. A role for mammalian Sin3 in permanent gene silencing. Mol. Cell 32:359-370.
40. Wang, Z., C. Zang, K. Cui, D. E. Schones, A. Barski, W. Peng, and K. Zhao. 2009. Genome-wide mapping of HATs and HDACs reveals distinct functions in active and inactive genes. Cell 138:1019-1031.
41. Zhang, Y., T. Liu, C. A. Meyer, J. Eeckhoute, D. S. Johnson, B. E. Bernstein, C. Nussbaum, R. M. Myers, M. Brown, W. Li, and X. S. Liu. 2008. Modelbased analysis of ChIP-Seq (MACS). Genome Biol. 9:R137.