S100A10 downregulation inhibits the phagocytosis of Cryptococcus neoformans by murine brain microvascular endothelial cells

Microbial Pathogenesis

Volumn 51, Issue 3, 2011, Pages 96-100

  Chen, Yuchong ^a   Chen, Jianghan ^b   Wen, Hai ^b   Gao, Pinghui ^c   Wang, Jun ^c   Zheng, Zhizhong ^a   Gu, Julin ^b  

^a FUDAN UNIVERSITY   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

^c SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Cryptococcus neoformans; Murine brain microvascular endothelial cell (MBMEC); RNA interference; S100A10

Indexed keywords

CALCIUM ION; PROTEIN S 100; PROTEIN S100A10; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN CELL; CALCIUM CELL LEVEL; CELL BUDDING; CELL FUNCTION; CONTROLLED STUDY; CRYPTOCOCCOSIS; CRYPTOCOCCUS NEOFORMANS; DOWN REGULATION; ENDOCYTOSIS; FUNGAL MORPHOLOGY; FUNGAL VIRULENCE; FUNGUS GROWTH; FUNGUS TRANSMISSION; GENE EXPRESSION REGULATION; GENE SILENCING; MICROVASCULAR ENDOTHELIAL CELL; MOUSE; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING;

ANIMALS; ANNEXIN A2; BRAIN; CALCIUM; CRYPTOCOCCUS NEOFORMANS; CYTOSOL; ENDOTHELIAL CELLS; GENE KNOCKDOWN TECHNIQUES; GENE SILENCING; MICE; PHAGOCYTOSIS; RNA, SMALL INTERFERING; S100 PROTEINS;

FILOBASIDIELLA NEOFORMANS; MURINAE;

EID: 79959344251     PISSN: 08824010     EISSN: 10961208     Source Type: Journal    
DOI: 10.1016/j.micpath.2011.05.003     Document Type: Article

References (18)

1. Levitz S.M. The ecology of Cryptococcus neoformans and the epidemiology of cryptococcosis. Rev Infect Dis 1991, 13(6):1163-1169.
2. Perfect JR: cryptococcosis. Infect Dis Clin North Am 1989, 3(1):77-102.
3. Ibrahim A.S., Filler S.G., Alcouloumre M.S., Kozel T.R., Edwards J.E., Ghannoum M.A. Adherence to and damage of endothelial cells by Cryptococcus neoformans in vitro: role of the capsule. Infect Immun 1995, 63(11):4368-4374.
4. Santamaria-Kisiel L., Rintala-Dempsey A.C., Shaw G.S. Calcium-dependent and -independent interactions of the S100 protein family. Biochem J 2006, 396(2):201-214.
5. Eckert R.L., Broome A.M., Ruse M., Robinson N., Ryan D., Lee K. S100 proteins in the epidermis. J Invest Dermatol 2004, 123(1):23-33.
6. He K.L., Deora A.B., Xiong H., Ling Q., Weksler B.B., Niesvizky R., et al. Endothelial cell annexin A2 regulates polyubiquitination and degradation of its binding partner S100A10/p11. J Biol Chem 2008, 283(28):19192-19200.
7. Zhang L., Li H., Su T.P., Barker J.L., Maric D., Fullerton C.S., et al. p11 is up-regulated in the forebrain of stressed rats by glucocorticoid acting via two specific glucocorticoid response elements in the p11 promoter. Neuroscience 2008, 153(4):1126-1134.
8. Rescher U., Gerke V. S100A10/p11: family, friends and functions. Pflugers Arch 2008, 455(4):575-582.
9. Diakonova M., Gerke V., Ernst J., Liautard J.P., van der Vusse G., Griffiths G. Localization of five annexins in J774 macrophages and on isolated phagosomes. J Cell Sci 1997, 110(Pt 10):1199-1213.
10. Jung M.J., Murzik U., Wehder L., Hemmerich P., Melle C. Regulation of cellular actin architecture by S100A10. Exp Cell Res 2010.
11. Roseff S.A., Levitz S.M. Effect of endothelial cells on phagocyte-mediated anticryptococcal activity. Infect Immun 1993, 61(9):3818-3824.
12. Chang Y.C., Stins M.F., McCaffery M.J., Miller G.F., Pare D.R., Dam T., et al. Cryptococcal yeast cells invade the central nervous system via transcellular penetration of the blood-brain barrier. Infect Immun 2004, 72(9):4985-4995.
13. Pardridge W.M. Blood-brain barrier biology and methodology. J Neurovirol 1999, 5(6):556-569.
14. Jong A., Wu C.H., Prasadarao N.V., Kwon-Chung K.J., Chang Y.C., Ouyang Y., et al. Invasion of Cryptococcus neoformans into human brain microvascular endothelial cells requires protein kinase C-alpha activation. Cell Microbiol 2008, 10(9):1854-1865.
15. van de Graaf S.F., Hoenderop J.G., Gkika D., Lamers D., Prenen J., Rescher U., et al. Functional expression of the epithelial Ca(2+) channels (TRPV5 and TRPV6) requires association of the S100A10-annexin 2 complex. Embo J 2003, 22(7):1478-1487.
16. Stommel J.M., Wahl G.M. Accelerated MDM2 auto-degradation induced by DNA-damage kinases is required for p53 activation. Embo J 2004, 23(7):1547-1556.
17. Cui B., Johnson S.P., Bullock N., Ali-Osman F., Bigner D.D., Friedman H.S. Bifunctional DNA alkylator 1,3-Bis(2-chloroethyl)-1-nitrosourea activates the ATR-Chk1 pathway independently of the mismatch repair pathway. Mol Pharmacol 2009, 75(6):1356-1363.
18. Haudenschild C.C., Cotran R.S., Gimbrone M.A., Folkman J. Fine structure of vascular endothelium in culture. J Ultrastruct Res 1975, 50(1):22-32.