Biomimetic nanostructured materials - potential regulators for osteogenesis?

Annals of the Academy of Medicine Singapore

Volumn 40, Issue 5, 2011, Pages 213-222

  Ngiam, Michelle ^a   Nguyen, Luong Th ^a   Liao, Susan ^b   Chan, Casey K ^a,c   Ramakrishna, Seeram ^a,d,e  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

^c National University Hospital

^d KING SAUD UNIVERSITY   (Saudi Arabia)

^e INSTITUTE OF MATERIALS RESEARCH AND ENGINEERING   (Singapore)

Author keywords

Biomaterials; Biomimetic; Bone; Hydroxyapatites; Nanomaterials; Stem cells; Tissueengineering

Indexed keywords

ALBUMIN; ALKALINE PHOSPHATASE; BONE SIALOPROTEIN; COLLAGEN TYPE 1; FIBRONECTIN; HYDROXYAPATITE; INTEGRIN; MITOGEN ACTIVATED PROTEIN KINASE; MOLECULAR SCAFFOLD; NANOMATERIAL; NANOTUBE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SCLEROPROTEIN; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR RUNX2; VITRONECTIN;

BIOMIMETICS; BIOMINERALIZATION; BONE DEVELOPMENT; BONE GRAFT; BONE REGENERATION; CELL FATE; ELECTROMAGNETIC FIELD; HUMAN; INTRACELLULAR SIGNALING; MESENCHYMAL STEM CELL; NANOFABRICATION; NONHUMAN; OSTEOBLAST; PHENOTYPIC VARIATION; POROSITY; REVIEW; TISSUE ENGINEERING; TOPOGRAPHY;

EID: 79959314814     PISSN: 03044602     EISSN: 29724066     Source Type: Journal    
DOI: None     Document Type: Review

References (67)

1. Greenwald AS, Boden SD, Goldberg VM, Khan Y, Laurencin CT, Rosier RN; American Academy of Orthopaedic Surgeons. The Committee on Biological Implants. Bone-graft substitutes: facts, fi ctions, and applications. J Bone Joint Surg Am 2001;83:S98-S103.
2. Steinmann JC, Herkowitz HN. Pseuarthrosis of the spine. Clin Orthop 1992;284:80-90.
3. Lee K, Roper J, Wang J. Demineralized bone matrix and spinal arthrodesis. Spine J 2005;5:S217S-S2223.
4. U.S. Medical Devices Market Outlook 2008. Frost & Sullivan, 5:16-5:28.
5. Desai BM. Osteobiologics. Am J Orthop 2007;36:8-11.
6. Lee K, Roper J, Wang J. Demineralized bone matrix and spinal arthrodesis. Spine J 2005;5:S217-S223.
7. Muschler GF, Raut VP, Patterson TE, Wenke JC, Hollinger JO. The design and use of animals models for translational research in bone tissue engineering and regenerative medicine. Tissue Eng Part B: Rev 2010;16:123-45.
8. Both SK, van der Muijsenberg AJ, van Blitterswijk CA, de Boer J, de Bruijn JD. A rapid and effi cient method for expansion of humanmesenchymal stem cells. Tissue Eng 2007;13:3-9.
9. Tian XF, Heng BC, Ge X, Lu K, Rufaihah AJ, Fan VT, et al. Comparison of osteogenesis of human embryonic stem cells within 2D and 3D culture systems. Scand J Clin Lab Invest 2008;68:58-67.
10. Chan CK, Kumar TS, Liao S, Murugan R, Ngiam M, Ramakrishnan S. Biomimetic nanocomposites for bone graft applications. Nanomedicine(Lond) 2006;1:177-88.
11. Thomson JA, Itskovitz-Eldor J, Shapiro SS, Waknitz MA, Swiergiel JJ, Marshall VS, et al. Embryonic stem cells lines derived from humanblastocysts. Science 1998;282:1145-7.
12. Evans M, Kaufman M. Establishment in culture of pluripotential cells from mouse embryos. Nature 1981;292:154-6.
13. Martin G. Isolation of a pluripotent cell line from early mouse embryoscultured in medium conditioned by tetracarcinoma stem cells. Proc NatlAcad Sci USA 1981;78:7634-8.
14. Bradley A, Evans M, Kaufman MH, Robertson E. Formation of germlikechimaeras from embryo-derived teratocarcinoma cell lines. Nature 1984;309:255-6.
15. Pittenger MF, Mackey AM, Beck SC, Jaiswal RK, Douglas R, Mosca JD, et al. Multilineage potential of adult human mesenchymal stem cells. Science 1999;284:143-7.
16. Wang HS, Hung SC, Peng ST, Huang CC, Wei HM, Guo YJ, et al. Mesechymal stem cells in the Wharton's jelly of the human umbilicalcord. Stem Cells 2004;22:1330-7.
17. Jeon O, Rhie JW, Kwon IK, Kim JH, Kim BS, Lee SH. In vivo boneformation following transplantation of human adipose-derived stromalcells that are not differentiated osteogenically. Tissue Eng Part A 2008;14:1285-94.
18. Gentleman E, Swain RJ, Evans ND, Boonrungsiman S, Jell G, Ball MD, et al. Comparative materials differences revealed in engineered boneas a function of cell-specific differentiation. Nat Mater 2009;8:763-70.
19. Chen Y, Shao JZ, Xiang LX, Dong XJ, Zhang GR. Mesenchymal stemcells: a promising candidate in regenerative medicine. Int J BiochemCell Biol 2008;40:815-20.
20. Nakajima T, Iizuka H, Tsutsumi S, Kayakabe M, Takagishi K. Evaluation of posterolateral spinal fusion using mesenchymal stem cells: differences with or without osteogenic differentation. Spine 2007;32:2432-6.
21. Morishita T, Honoki K, Ohgushi H, Kotobuki N, Matsushima A, Takakura Y. Tissue engineering approach to the treatment of bone tumors: three cases of cultured bone grafts derived from patients' mesenchymal stem cells. Artif Organs 2006;30:115-8.
22. Minamide A, Yoshida M, Kawakami M, Okada M, Enyo Y, Hashizume H, et al. The effects of bone morphogenetic protein and basic fi broblast growth factor on cultured mesenchymal stem cells for spine fusion. Spine(Phila Pa 1976) 2007;32:1067-71.
23. Reddi AH. Role of morphogenetic proteins in skeletal tissue engineering and regeneration. Nat Biotechnol 1998;16:247-52.
24. Liao SS, Guan K, Cui FZ, Shi SS, Sun TS. Lumbar spinal fusion witha mineralized collagen matrix and rhBMP-2 in a rabbit model. Spine 2003;28:1954-60.
25. Jørgensen NR, Henriksen Z, Sørensen OH, Civitelli R. Dexamethasone,BMP-2, and 1,25-dihydroxyvitamin D enhance a more differentiatedosteoblast phenotype: validation of an in vitro model for human bonemarrow-derived primary osteoblasts. Steroids 2004;69:219-26.
26. Gupta A, Leong DT, Bai HF, Singh SB, Lim TC, Hutmacher DW. Osteomaturation of adipose-derived stem cells required the combined action ofvitamin D3, beta-glycerophosphate, and ascorbic acid. Biochem BiophysRes Commun 2007;362:17-24.
27. Choong CS, Hutmacher DW, Triffitt JT. Co-culture of bone marrowfibroblasts and endothelial cells on modified polycaprolactone substrates for enhanced potentials in bone tissue engineering. TissueEng 2006;12:2521-31.
28. Fujihara K, Kotaki M, Ramakrishna S. Guided bone regenerationmembrane made of polyprolactone/calcium carbonated composite nanofibers. Biomaterials 2005;26:4139-47.
29. Ngiam M, Liao S, Patil AJ, Cheng Z, Yang F, Gubler MJ, et al. Fabricationof mineralized polymeric nanofi brous composites for bone graft materials. Tissue Eng Part A 2009;15:535-46.
30. Ngiam M, Liao S, Patil AJ, Cheng Z, Chan CK, Ramakrishna S. Thefabrication of nano-hydroxyapatite on PLGA and PLGA/collagennano fibrous composite scaffolds and their effects in osteoblastic behavior for bone tissue engineering. Bone 2009;45:4-16.
31. Ke Y, Wang YJ, Ren L, Zhao QC, Huang W. Modifi ed PHBV scaffoldsby in situ UV polymerization: structural characteristic, mechanicalproperties and bone mesenchymal stem cell compatibility. Acta Biomater 2010;6:1329-36
32. Shih YRV, Chen CN, Tsai SW, Wang YJ, Lee OK. Growth of mesenchymalstem cells on electrospun type I collagennanofibers. Stem Cells 2006;24:2391-7.
33. Oliveira JM, Rodrigues MT, Silva SS, Malafaya PB, Gomes ME, Viegas CA, et al. Novel hydroxyapatite/chitosan bilayered scaffoldfor osteochondral tissue-engineering applications: Scaffold design andits performance when seeded with goat bone marrow stromal cells. Biomaterials 2006;27:6123-37.
34. Awad H, Wickham M, Leddy H, Gimble J, Guilak F. Chondrogenic differentiation of adipose-derived adult stem cells in agarose, alginate,and gelatin scaffolds. Biomaterials 2004;25:3211-22.
35. Li C, Vepari C, Jin HJ, Kim HJ, Kaplan DL. Electrospun silk-BMP-2scaffolds for bone tissue engineering. Biomaterials 2006;27: 3115-24.
36. Lutolf MP, Gilbert PM, Blau HM. Designing materials to direct stem-cellfate. Nature 2009;462:433-41.
37. Dawson JI, Wahl DA, Lanham SA, Kanczler JM, Czernuszka JT, Oreffo ROC. Development of specifi c collagen scaffolds to support the osteogenicand chondrogenic differentiation of human bone marrow stromal cells. Biomaterials 2008;29:3105-16.
38. Vasita R, Katti DS. Nanofi bers and their applications in tissue engineering. Int J Nanomedicine 2006;1:15-30.
39. Saw S, Wang K, Yong T, Ramakrishna S. Polymeric nanofibers in tissue engineering. In: Challa SSR Kumar, editor. Tissue, Cell and Organ Engineering. Wiley-VCH Verlag GmbH & Co, 2006.
40. Teo WE, Ramakrishna S. A review on electrospinning design and nanofi breassemblies. Nanotechnology 2006;17:R89-R106.
41. Teo W, Gopal R, Ramaseshan R, Fujihara K, Ramakrishna S. A dynamicliquid support system for continuous electrospun yarn fabrication. Polymer 2007;48:3400-5.
42. Teo W, Liao S, Chan C, Ramakrishna S. Remodeling of three-dimension alhier archically organized nanofi brous assemblies. Current Nanoscience 2008;4:361-9.
43. Kim BS, Mooney DJ. Development of biocompatible syntheticextracellular matrices for tissue engineering. Trends Biotechnol 1998;16:224-30.
44. Dalby MJ, Gadegaard N, Tare R, Andar A, Riehle MO, Herzyk P, et al. The control of human mesenchymal cell differentiation using nanoscale symmetry and disorder. Nat Mater 2007;6:997-1003.
45. Park J, Bauer S, von der Mark K, Schmuki P. Nanosize and vitality:TiO2 nanotube diameter directs cell fate. Nano Lett 2007;7:1686-91.
46. Oh S, Brammer KS, Li YS, Teng D, Engler AJ, Chien S, et al. Stem cellfate dictated solely by altered nanotube dimension. Proc Natl Acad SciU S A 2009;106:2130-5.
47. Mata A, Kim EJ, Boehm CA, Fleischman AJ, Muschler GF, Roy S. A three-dimensional scaffold with precise micro-architecture and surface micro-textures. Biomaterials 2009;30:4610-7.
48. Laurencin CT, Ambrosio AM, Borden MD, Cooper JA. Tissue engineering:orthopedic applications. Annu Rev Biomed Eng 1999;1:19-46.
49. Woo KM, Chen VJ, Ma PX. Nano-fibrous scaffolding architecture selectively enhances protein adsorption contributing to cell attachment. J Biomed Mater Res A 2003;67:531-7.
50. Woo KM, Jun JH, Chen VJ, Seo J, Baek JH, Ryoo HM, et al. Nano-fi brousscaffolding promotes osteoblast differentiation and biomineralization. Biomaterials 2007;28:335-43.
51. Yang XB, Bhatnagar RS, Li S, Oreffo RO. Biomimetic collagenscaffolds for human bone cell growth and differentiation. Tissue Eng 2004;10:1148-59.
52. Jikko A, Harris SE, Chen D, Mendrick DL, Damsky CH. Collagen integrinreceptors regulate early osteoblast differentiation induced by BMP-2. JBone Miner Res 1999;14:1075-83.
53. Mizuno M, Fujisawa R, Kuboki Y. Type I collagen-induced osteo blastic differentiation of bone-marrow cells mediated by collagen-alpha2beta1integrin interaction. J Cell Physiol 2000;184:207-13.
54. Prabhakaran MP, Venugopal J, Ramakrishna S. Electrospun nanostructuredscaffolds for bone tissue engineering. Acta Biomater 2009;5:2884-93.
55. Bernhardt A, Lode A, Boxberger S, Pompe W, Gelinsky M. Mineralised collagen-an artificial, extra cellular bone matrix--improves osteogenic differentiation of bone marrow stromal cells. J Mater Sci Mater Med 2008;19:269-75.
56. Ichinohe N, Takamoto T, Tabata Y. Proliferation, osteogenic differentiation,and distribution of rat bone marrow stromal cells in nonwoven fabrics by different culture methods. Tissue Eng Part A 2008;14:107-16.
57. Lin L, Chow KL, Leng Y. Study of hydroxyapatite osteoinductivity withan osteogenic differentiation of mesenchymal stem cells. J Biomed MaterRes A 2009;89:326-35.
58. Lee JH, Rim NG, Jung HS, Shin H. Control of osteogenic differentiationand mineralization of human mesenchymal stem cells on compositenanofi bers containing poly[lactic-co-(glycolic acid)] and hydroxyapatite. Macromol Biosci 2010;10:173-82.
59. Deligianni DD, Katsala ND, Koutsoukos PG, Missirlis YF. Effect ofsurface roughness of hydroxyapatite on human bone marrow cell adhesion,proliferation, differentiation and detachment strength. Biomaterials 2001;22:87-96.
60. Chou Y, Dunn J, Wu B. In vitro response of MC3T3-E1 pre-osteoblastswithin three-dimensional apatite-coated PLGA scaffolds. J Biomed Mater Res B Appl Biomater 2005;75:81-90.
61. Engler AJ, Sen S, Sweeney HL, Discher DE. Matrix elasticity directsstem cell lineage specifi cation. Cell 2006;126:677-89.
62. Khatiwala CB, Peyton SR, Metzke M, Putnam AJ. The regulation ofosteogenesis by ECM rigidity in MC3T3-E1 cells requires MAPKactivation. J Cell Physiol 2007;211:661-72.
63. Khatiwala CB, Kim PD, Peyton SR, Putnam AJ. ECM complianceregulates osteogenesis by influencing MAPK signaling downstream of RhoA and ROCK. J Bone Miner Res 2009;24:886-98.
64. Rowlands AS, George PA, Cooper-White JJ. Directing osteogenic andmyogenic differentiation of MSCs: interplay of stiffness and adhesivelig and presentation. Am J Physiol Cell Physiol 2008;295:C1037-44.
65. Appleford MR, Oh S, Cole JA, Carnes DL, Lee M, Bumgardner JD, etal. Effects of trabecular calcium phosphate scaffolds on stress signaling in osteo blast precursor cells. Biomaterials 2007;28:2747-53.
66. Naveiras O, Nardi V, Wenzel PL, Hauschka PV, Fahey F, Daley GQ.Bone-marrow adipocytes as negative regulators of the haematopoietic micro environment. Nature 2009;460:259-63.
67. Nuttall ME, Gimble JM. Controlling the balance between osteoblastogenesis and adipogenesis and the consequent therapeutic implications. Curr Opin Pharmacol 2004;4:290-4.