The effects of intraduodenal nutrient infusion on serum CCK, LES pressure, and gastroesophageal reflux

Neurogastroenterology and Motility

Volumn 23, Issue 7, 2011, Pages

  Lacy, B E ^a   Carter, J ^a   Weiss, J E ^b   Crowell, M D ^c  

^a DARTMOUTH HITCHCOCK MEDICAL CENTER   (United States)

^b DARTMOUTH MEDICAL SCHOOL   (United States)

^c MAYO CLINIC   (United States)

Author keywords

Acid reflux; Cholecystokinin; Esophagus; Fat; Gastroesophageal reflux disease; Impedance; Lower esophageal sphincter; PH monitoring

Indexed keywords

CARBOHYDRATE; CHOLECYSTOKININ; FAT; PROTEIN;

ADULT; AGED; ARTICLE; CHOLECYSTOKININ BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; ESOPHAGEAL PH MONITORING; ESOPHAGUS MOTILITY; FEMALE; GASTROESOPHAGEAL REFLUX; HUMAN; IMPEDANCE; LOWER ESOPHAGUS SPHINCTER PRESSURE; MALE; NUTRIENT SOLUTION; PRIORITY JOURNAL;

ADULT; CATHETERS; CHOLECYSTOKININ; DIETARY CARBOHYDRATES; DIETARY FATS; DIETARY PROTEINS; ESOPHAGEAL SPHINCTER, LOWER; FEMALE; FOOD; GASTROESOPHAGEAL REFLUX; HUMANS; INCIDENCE; MALE; PRESSURE;

EID: 79959310255     PISSN: 13501925     EISSN: 13652982     Source Type: Journal    
DOI: 10.1111/j.1365-2982.2011.01701.x     Document Type: Article

References (41)

1. Dent J, Dodd WJ, Friedman RH et al. Mechanism of gastroesophageal reflux in recumbent asymptomatic human subjects. J Clin Invest 1980; 65: 256-67.
2. Dodds WJ, Dent J, Hogan WJ et al. Mechanisms of gastroesophageal reflux in patients with reflux esophagitis. N Engl J Med 1982; 307: 1547-52.
3. Mittal RK, McCallum RW. Characteristics and frequency of transient relaxations of the lower esophageal sphincter in patients with reflux esophagitis. Gastroenterology 1988; 95: 593-9.
4. Holloway RH, Dent J. Pathophysiology of gastroesophageal reflux. Lower esophageal sphincter dysfunction in reflux disease. Gastroenterol Clin North Am 1990; 19: 517-35.
5. Kahrilas PJ. The role of hiatus hernia in GERD. Yale J Biol Med 1999; 72: 101-11.
6. Franzi SJ, Martin CJ, Cox MR, Dent J. Response of canine lower esophageal sphincter to gastric distension. Am J Physiol 1990; 259: G380-5.
7. Holloway RH, Hongo M, Berger K, McCallum RW. Gastric distention: a mechanism for postprandial gastroesophageal reflux. Gastroenterology 1985; 89: 779-84.
8. Holloway RH, Kocyan P, Dent J. Provocation of transient lower esophageal sphincter relaxations by meals in patients with symptomatic gastroesophageal reflux. Dig Dis Sci 1991; 36: 1034-9.
9. Penagini R, Bartesaghi B, Conte D, Bianchi PA. Rate of transient lower oesophageal sphincter relaxations of healthy humans after eating a mixed nutrient meal: time course and comparison with fasting. Eur J Gastroenterol Hepatol 1992; 4: 35-8.
10. Ergun GA, Kahrilas PJ, Lin S, Logemann JA, Harig JM. Shape, volume, and content of the deglutitive pharyngeal chamber imaged by ultrafast computerized tomography. Gastroenterology 1993; 105: 1396-403.
11. Raybould HE, Lloyd KC. Integration of postprandial function in the proximal gastrointestinal tract. Role of CCK and sensory pathways. Ann N Y Acad Sci 1994; 713: 143-56.
12. Katschinski M, Schirra J, Koppelberg T et al. Effects of cholecystokinin-A-receptor blockade on oesophageal motility. Eur J Gastroenterol Hepatol 1994; 6: 983-9.
13. Boulant J, Mathieu S, D'Amato M et al. Cholecystokinin in transient lower oesophageal relaxation due to gastric distension in humans. Gut 1997; 40: 575-81.
14. Dockray GJ. Gastrointestinal hormones: cholecystokinin, somatostatin and ghrelin. In: Johnson LR, ed. Physiology of the Gastrointestinal Tract. Vol. 1 Amsterdam, The Netherlands: Elsevier Academic Press, 2006: 91-120.
15. Nebel OT, Castell DO. Lower esophageal sphincter pressure changes after food ingestion. Gastroenterology 1972; 63: 778-83.
16. Nebel OT, Castell DO. Inhibition of the lower oesophageal sphincter by fat - a mechanism for fatty food intolerance. Gut 1973; 14: 270-4.
17. Nebel OT, Fornes MF, Castell DO. Symptomatic gastroesophageal reflux: incidence and precipitating factors. Dig Dis Sci 1976; 21: 953-6.
18. Becker DJ, Sinclair J, Castell DO, Wu WC. A comparison of high and low fat meals on postprandial esophageal acid exposure. Am J Gastroenterol 1989; 84: 782-6.
19. Holloway RH, Lyrenas E, Ireland A, Dent J. Effect of intraduodenal fact on lower oesophageal sphincter function and gastro-oesophageal reflux. Gut 1997; 40: 449-53.
20. Zerbib F, Des Varannes SB, Scarpignato C et al. Endogenous cholecystokinin in postprandial lower esophageal sphincter function and fundic tone in humans. Am J Physiol 1998; 275: G1266-73.
21. Lacy BE, Paquette L, Kelly ML, Carter J, Weiss J. Effects of intraduodenal nutrient infusion on CCK levels, LES pressure, and gastroesophageal reflux. Am J Gastroenterol 2008; 103: S31.
22. Holloway RH, Penagini R, Ireland AC. Criteria for objective definition of transient lower esophageal sphincter relaxation. Am J Physiol 1995; 31: G128-33.
23. Sifrim D, Castell D, Dent J, Kahrilas PJ. Gastroesophageal reflux monitoring: review and consensus report on detection and definitions of acid, non-acid and gas reflux. Gut 2004; 53: 1024-31.
24. Bredenoord AJ, Weusten BLAM, Timmer R, Smouth AJPM. Reproducibility of multichannel intraluminal electrical impedance monitoring of gastroesophageal reflux. Am J Gastroenterol 2005; 100: 265-9.
25. Pehl C, Waizenhoefer A, Wendl B et al. Effect of low and high fat meals on lower esophageal sphincter motility and gastroesophageal reflux in healthy subjects. Am J Gastroenterol 1999; 94: 1192-6.
26. Mittal RK, Holloway RH, Penagini R, Blackshaw LA, Dent J. Transient lower esophageal sphincter relaxation. Gastroenterology 1995; 109: 601-10.
27. Meyer BM, Werth BA, Beglinger C et al. Role of cholecystokinin in regulation of gastrointestinal motor functions. Lancet 1989; 21: 12-5.
28. Fried M, Erlacher U, Schwizer U et al. Role of cholecystokinin in the regulation of gastric emptying and pancreatic enzyme secretion in humans. Studies with the cholecystokinin-receptor antagonist loxiglumide. Gastroenterology 1991; 101: 503-11.
29. Heddle R, Dent J, Read NW et al. Antropyloroduodenal motor responses to intraduodenal lipid infusion in healthy volunteers. Am J Physiol 1988; 254: G671-9.
30. Houghton LA, Mangnall YF, Read NW. Effect of incorporating fat into a liquid test-meal on the relation between intragastric distribution and gastric emptying in human volunteers. Gut 1990; 31: 1226-9.
31. Feinle C, D'Amato M, Read NW. Cholecystokinin-A receptors modulate gastric sensory and motor responses to gastric distention and duodenal lipid. Gastroenterology 1996; 110: 1379-85.
32. Mesquita MA, Thompson DG, Troncon EA et al. Effect of cholecystokinin-A receptor blockade on lipid-induced gastric relaxation in humans. Am J Physiol 1997; 273: G118-23.
33. Yamagishi T, Debas HT. Cholecystokinin inhibits gastric emptying by acting on both proximal stomach and pylorus. Am J Physiol 1978; 234: E375-8.
34. Hidalgo L, Clave P, Estorch M et al. Effect of cholecystokinin-A receptor blockade on postprandial insulinaemia and gastric emptying in humans. Neurogastroenterol Motil 2002; 14: 519-25.
35. Trudgill NJ, Hussain FN, Moustafa M et al. The effect of cholecystokinin antagonism on postprandial lower oesophageal sphincter function in asymptomatic volunteers and patients with reflux disease. Aliment Pharmacol Ther 2001; 9: 1357-64.
36. Resin H, Stern DH, Sturdevant RAL, Isenberg JI. Effect of the c-terminal octapeptide of cholecystokinin on lower esophageal sphincter pressure in man. Gastroenterology 1973; 64: 946-9.
37. Fisher RS, Dimarino AJ, Cohen S. Mechanism of cholecystokinin inhibition of lower esophageal sphincter pressure. Am J Physiol 1975; 228: 1469-73.
38. Boulant J, Fioramonti J, Dapoigny M, Bommelaer G, Bueno L. Cholecystokinin and nitric oxide in transient lower esophageal sphincter relaxation to gastric distention in dogs. Gastroenterology 1994; 107: 1059-66.
39. Ledeboer M, Masclee AAM, Batstra MR, Jansen JBMJ, Lamers CBHW. Effect of cholecystokinin on lower oesophageal sphincter pressure and transient lower oesophageal sphincter relaxations in humans. Gut 1995; 36: 39-44.
40. Brazer SR, Borislow DS, Liddle RA. Cholecystokinin is not a major hormonal regulator of lower esophageal sphincter pressure. Gastroenterology 1990; 99: 641-5.
41. Raybould HE, Tache Y. Cholecystokinin inhibits gastric motility and emptying via a capsaicin-sensitive vagal pathway in rats. Am J Physiol 1988; 255: G242-6.