Adiponectin inhibits hyperlipidemia-induced platelet aggregation via attenuating oxidative/nitrative stress

Physiological Research

Volumn 60, Issue 2, 2011, Pages 347-354

  Wang, W Q ^a   Zhang, H F ^b   Gao, G X ^a   Bai, Q X ^a   Li, R ^b   Wang, X M ^b  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Adiponectin; Aggregation; Hyperlipidemia; Platelet

Indexed keywords

EID: 79959265421     PISSN: 08628408     EISSN: None     Source Type: Journal    
DOI: 10.33549/physiolres.932044     Document Type: Article

References (32)

1. BECKMAN JS, KOPPENOL WH: Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly. Am J Physiol 271: C1424-C1437, 1996.
2. BORN GV: Aggregation of blood platelets by adenosine diphosphate and its reversal. Nature 194: 927-929, 1962.
3. CHEN H, MONTAGNANI M, FUNAHASHI T, SHIMOMURA I, QUON MJ: Adiponectin stimulates production of nitric oxide in vascular endothelial cells. J Biol Chem 278: 45021-45026, 2003.
4. CHIA JS, LIN YL, LIEN HT, CHEN JY: Platelet aggregation induced by serotype polysaccharides from Streptococcus mutans. Infect Immun 72: 2605-2617, 2004.
5. COOPER-DEHOFF RM, PEPINE CJ: Metabolic syndrome and cardiovascular disease: challenges and opportunities. Clin Cardiol 30: 593-597, 2007.
6. COSENTINO F, HISHIKAWA K, KATUSIC ZS, LUSCHER TF: High glucose increases nitric oxide synthase expression and superoxide anion generation in human aortic endothelial cells. Circulation 96: 25-28, 1997.
7. ECKEL RH, BAROUCH WW, ERSHOW AG: Report of the National Heart, Lung, and Blood Institute-National Institute of Diabetes and Digestive and Kidney Diseases Working Group on the pathophysiology of obesityassociated cardiovascular disease. Circulation 105: 2923-2928, 2002.
8. EKMEKCI H, EKMEKCI OB, ERDINE S, SONMEZ H, ATAEV Y, OZTURK Z, BUTUN II, GUREL C, KUCUR M, TURFANER N, ULUTIN T, PURISA S, VURAL VA: Effects of serum homocysteine and adiponectin levels on platelet aggregation in untreated patients with essential hypertension. J Thromb Thrombolysis 28: 418-424, 2009.
9. FREEDMAN JE, LOSCALZO J, BARNARD MR, ALPERT C, KEANEY JF, MICHELSON AD: Nitric oxide released from activated platelets inhibits platelet recruitment. J Clin Invest 100: 350-356, 1997.
10. FREEDMAN JE, SAUTER R, BATTINELLI EM, AULT K, KNOWLES C, HUANG PL, LOSCALZO J: Deficient platelet-derived nitric oxide and enhanced hemostasis in mice lacking the NOSIII gene. Circ Res 84: 1416-1421, 1999.
11. GKALIAGKOUSI E, RITTER J, FERRO A: Platelet-derived nitric oxide signaling and regulation. Circ Res 101: 654-662, 2007.
12. GOLDSTEIN BJ, SCALIA R: Adiponectin: a novel adipokine linking adipocytes and vascular function. J Clin Endocrinol Metab 89: 2563-2568, 2004.
13. HOTTA K, FUNAHASHI T, ARITA Y, TAKAHASHI M, MATSUDA M, OKAMOTO Y, IWAHASHI H, KURIYAMA H, OUCHI N, MAEDA K, NISHIDA M, KIHARA S, SAKAI N, NAKAJIMA T, HASEGAWA K, MURAGUCHI M, OHMOTO Y, NAKAMURA T, YAMASHITA S, HANAFUSA T, MATSUZAWA Y: Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients. Arterioscler Thromb Vasc Biol 20: 1595-1599, 2000.
14. HUIE RE, PADMAJA S: The reaction of no with superoxide. Free Radic Res Commun 18: 195-199, 1993.
15. HULTHE J, BOKEMARK L, WIKSTRAND J, FAGERBERG B: The metabolic syndrome, LDL particle size, and atherosclerosis: the Atherosclerosis and Insulin Resistance (AIR) study. Arterioscler Thromb Vasc Biol 20: 2140-2147, 2000.
16. JUHAN-VAGUE I, VAGUE P: Interrelations between carbohydrates, lipids, and the hemostatic system in relation to the risk of thrombotic and cardiovascular disease. Am J Obstet Gynecol 163: 313-315, 1990.
17. KARPMAN D, PAPADOPOULOU D, NILSSON K, SJOGREN AC, MIKAELSSON C, LETHAGEN S: Platelet activation by Shiga toxin and circulatory factors as a pathogenetic mechanism in the hemolytic uremic syndrome. Blood 97: 3100-3108, 2001.
18. KATO H, KASHIWAGI H, SHIRAGA M, TADOKORO S, KAMAE T, UJIIE H, HONDA S, MIYATA S, IJIRI Y, YAMAMOTO J, MAEDA N, FUNAHASHI T, KURATA Y, SHIMOMURA I, TOMIYAMA Y, KANAKURA Y: Adiponectin acts as an endogenous antithrombotic factor. Arterioscler Thromb Vasc Biol 26: 224-230, 2006.
19. LI Z, XI X, GU M, FEIL R, YE RD, EIGENTHALER M, HOFMANN F, DU X: A stimulatory role for cGMP-dependent protein kinase in platelet activation. Cell 112: 77-86, 2003.
20. LI Z, ZHANG G, FEIL R, HAN J, DU X: Sequential activation of p38 and ERK pathways by cGMP-dependent protein kinase leading to activation of the platelet integrin alphaIIb beta3. Blood 107: 965-972, 2006.
21. MATSUZAWA Y, FUNAHASHI T, KIHARA S, SHIMOMURA I: Adiponectin and metabolic syndrome. Arterioscler Thromb Vasc Biol 24: 29-33, 2004.
22. MILWARD AD, RIBA R, PATEL B, OBERPRIELER NG, NASEEM KM: Sodium orthovanadate induced tyrosine phosphorylation of platelet nitric oxide synthase negatively regulates enzyme activity. Biochim Biophys Acta 1760: 1411-1417, 2006.
23. NASEEM KM, RIBA R: Unresolved roles of platelet nitric oxide synthase. J Thromb Haemost 6: 10-19, 2008.
24. OLAS B, WACHOWICZ B: Role of reactive nitrogen species in blood platelet functions. Platelets 18: 555-565, 2007.
25. OUCHI N, SHIBATA R, WALSH K: Cardioprotection by adiponectin. Trends Cardiovasc Med 16: 141-146, 2006.
26. 2+ mobilization and aggregation in platelets from type 2 diabetic patients. Biochem Biophys Res Commun 333: 794-802, 2005.
27. RIBA R, HUGHES CE, GRAHAM A, WATSON SP, NASEEM KM: Globular adiponectin induces platelet activation through the collagen receptor GPVI-Fc receptor gamma chain complex. J Thromb Haemost 6: 1012-1020, 2008.
28. RIDDELL DR, OWEN JS: Nitric oxide and platelet aggregation. Vitam Horm 57: 25-48, 1999.
29. SAKKINEN PA, WAHL P, CUSHMAN M, LEWIS MR, TRACY RP: Clustering of procoagulation, inflammation, and fibrinolysis variables with metabolic factors in insulin resistance syndrome. Am J Epidemiol 152: 897-907, 2000.
30. SANGUIGNI V, PIGNATELLI P, CACCESE D, PULCINELLI FM, LENTI L, MAGNATERRA R, MARTINI F, LAURO R, VIOLI F: Increased superoxide anion production by platelets in hypercholesterolemic patients. Thromb Haemost 87: 796-801, 2002.
31. SASE K, MICHEL T: Expression of constitutive endothelial nitric oxide synthase in human blood platelets. Life Sci 57: 2049-2055, 1995.
32. YAO D, VLESSIDIS AG, GOU Y, ZHOU X, ZHOU Y, EVMIRIDIS NP: Chemiluminescence detection of superoxide anion release and superoxide dismutase activity: modulation effect of Pulsatilla chinensis. Anal Bioanal Chem 379: 171-177, 2004.