In vivo pharmacodynamics of torezolid phosphate (TR-701), a new oxazolidinone antibiotic, against methicillin-susceptible and methicillin-resistant Staphylococcus aureus strains in a mouse thigh infection model

Antimicrobial Agents and Chemotherapy

Volumn 55, Issue 7, 2011, Pages 3453-3460

  Louie, Arnold ^a   Liu, Weiguo ^a   Kulawy, Robert ^a   Drusano, G L ^a  

^a ORDWAY RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

OXAZOLIDINONE DERIVATIVE; TEDIZOLID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBACTERIAL ACTIVITY; ANTIMICROBIAL ACTIVITY; AREA UNDER THE CURVE; ARTICLE; COLONY FORMING UNIT; COMMUNITY ASSESSMENT; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; IN VIVO STUDY; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS INFECTION; METHICILLIN SUSCEPTIBLE STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; MOUSE; NONHUMAN; PHARMACODYNAMICS; PRIORITY JOURNAL; SINGLE DRUG DOSE; THIGH INFECTION;

ACETAMIDES; ANIMALS; ANTI-BACTERIAL AGENTS; FEMALE; HUMANS; METHICILLIN; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICE; MICROBIAL SENSITIVITY TESTS; OXAZOLES; OXAZOLIDINONES; PHOSPHORIC ACID ESTERS; SERUM; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; TETRAZOLES; THIGH;

EID: 79959194196     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01565-10     Document Type: Article

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