Evaluation of selected antitumor agents as subversive substrate and potential inhibitor of trypanothione reductase: An alternative approach for chemotherapy of Leishmaniasis

Molecular and Cellular Biochemistry

Volumn 352, Issue 1-2, 2011, Pages 261-270

  Shukla, Anil Kumar ^a   Patra, Sanjukta ^a   Dubey, Vikash Kumar ^a  

^a INDIAN INSTITUTE OF TECHNOLOGY GUWAHATI   (India)

Author keywords

Antitumor agents; Enzyme inhibition; Leishmaniasis; Protein

Indexed keywords

5,5' DITHIOBIS(2 NITROBENZOIC ACID); DOXORUBICIN; MITOMYCIN C; OXIDOREDUCTASE INHIBITOR; QUINONE DERIVATIVE; REACTIVE OXYGEN METABOLITE; THIOL; TRYPANOTHIONE REDUCTASE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CHEMOTHERAPY; COMPUTER MODEL; DRUG PROTEIN BINDING; DRUG TARGETING; ENZYME ACTIVITY; ENZYME PURIFICATION; ENZYME SUBSTRATE; ERYTHROCYTE; FLOW CYTOMETRY; GROWTH INHIBITION; HEMOLYSIS; HUMAN; HUMAN CELL; IC 50; INFRARED SPECTROSCOPY; LEISHMANIA; LEISHMANIA DONOVONI; LEISHMANIA INFANTUM; LEISHMANIASIS; MICROBIAL GROWTH; NONHUMAN; OXIDATIVE STRESS; PARASITE CULTIVATION; PROMASTIGOTE; PROTEIN EXPRESSION; TOXICITY;

ANTIPROTOZOAL AGENTS; DRUG EVALUATION, PRECLINICAL; HUMANS; LEISHMANIASIS; NADH, NADPH OXIDOREDUCTASES; SUBSTRATE SPECIFICITY;

EID: 79959193767     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-011-0762-0     Document Type: Article

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