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Volumn 117, Issue 24, 2011, Pages 6685-6693

Activated protein C cofactor function of protein S: A novel role for a γ-carboxyglutamic acid residue

Author keywords

[No Author keywords available]

Indexed keywords

4 CARBOXYGLUTAMIC ACID; ACTIVATED PROTEIN C; BLOOD CLOTTING FACTOR 5A; EPIDERMAL GROWTH FACTOR; PHOSPHOLIPID; PHOSPHOLIPID BINDING PROTEIN; PROTEIN S;

EID: 79959187738     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2010-11-317099     Document Type: Article
Times cited : (37)

References (44)
  • 1
    • 20444427991 scopus 로고    scopus 로고
    • The anticoagulant protein C pathway
    • DOI 10.1016/j.febslet.2005.03.001, PII S0014579305003066
    • Dahlback B, Villoutreix BO. The anticoagulant protein C pathway. FEBS Lett. 2005;579(15): 3310-3316. (Pubitemid 40804679)
    • (2005) FEBS Letters , vol.579 , Issue.15 , pp. 3310-3316
    • Dahlback, B.1    Villoutreix, B.O.2
  • 3
    • 43749120255 scopus 로고    scopus 로고
    • Protein S enhances the tissue factor pathway inhibitor inhibition of factor Xa but not its inhibition of factor VIIa-tissue factor
    • DOI 10.1111/j.1538-7836.2008.02980.x
    • Ndonwi M, Broze G Jr. Protein S enhances the tissue factor pathway inhibitor inhibition of factor Xa but not its inhibition of factor VIIa-tissue factor. J Thromb Haemost. 2008;6(6):1044-1046. (Pubitemid 351689932)
    • (2008) Journal of Thrombosis and Haemostasis , vol.6 , Issue.6 , pp. 1044-1046
    • Ndonwi, M.1    Broze Jr., G.2
  • 5
    • 55949086628 scopus 로고    scopus 로고
    • Protein S deficiency: A clinical perspective
    • ten Kate MK, van der Meer J. Protein S deficiency: a clinical perspective. Haemophilia. 2008; 14(6):1222-1228.
    • (2008) Haemophilia , vol.14 , Issue.6 , pp. 1222-1228
    • Ten Kate, M.K.1    Van Der Meer, J.2
  • 6
    • 60849133332 scopus 로고    scopus 로고
    • High long-term absolute risk of recurrent venous thromboembolism in patients with hereditary deficiencies of protein S, protein C or antithrombin
    • Brouwer JL, Lijfering WM, ten Kate MK, et al. High long-term absolute risk of recurrent venous thromboembolism in patients with hereditary deficiencies of protein S, protein C or antithrombin. Thromb Haemost. 2009;101(1):93-99.
    • (2009) Thromb Haemost , vol.101 , Issue.1 , pp. 93-99
    • Brouwer, J.L.1    Lijfering, W.M.2    Ten Kate, M.K.3
  • 7
    • 0031964419 scopus 로고    scopus 로고
    • Clarification of the risk for venous thrombosis associated with hereditary protein S deficiency by investigation of a large kindred with a characterized gene defect
    • Simmonds RE, Ireland H, Lane DA, et al. Clarification of the risk for venous thrombosis associated with hereditary protein S deficiency by investigation of a large kindred with a characterized gene defect. Ann Intern Med. 1998;128(1):8-14. (Pubitemid 28016712)
    • (1998) Annals of Internal Medicine , vol.128 , Issue.1 , pp. 8-14
    • Simmonds, R.E.1    Ireland, H.2    Lane, D.A.3    Zoller, B.4    Garcia, D.F.P.5    Dahlback, B.6
  • 9
    • 0021740029 scopus 로고
    • Plasma protein S deficiency in familial thrombotic disease
    • Schwarz HP, Fischer M, Hopmeier P, Batard MA, Griffin JH. Plasma protein S deficiency in familial thrombotic disease. Blood. 1984;64(6):1297-1300. (Pubitemid 15224546)
    • (1984) Blood , vol.64 , Issue.6 , pp. 1297-1300
    • Schwarz, H.P.1    Fischer, M.2    Hopmeier, P.3
  • 10
    • 70349656483 scopus 로고    scopus 로고
    • Lack of Protein S in mice causes embryonic lethal coagulopathy and vascular dysgenesis
    • Burstyn-Cohen T, Heeb MJ, Lemke G. Lack of Protein S in mice causes embryonic lethal coagulopathy and vascular dysgenesis. J Clin Invest. 2009;119(10):2942-2953.
    • (2009) J Clin Invest , vol.119 , Issue.10 , pp. 2942-2953
    • Burstyn-Cohen, T.1    Heeb, M.J.2    Lemke, G.3
  • 11
    • 70349575804 scopus 로고    scopus 로고
    • Generation and phenotypic analysis of protein S-deficient mice
    • Saller F, Brisset AC, Tchaikovski SN, et al. Generation and phenotypic analysis of protein S-deficient mice. Blood. 2009;114(11):2307-2314.
    • (2009) Blood , vol.114 , Issue.11 , pp. 2307-2314
    • Saller, F.1    Brisset, A.C.2    Tchaikovski, S.N.3
  • 12
    • 0040426308 scopus 로고
    • High molecular weight complex in human plasma between vitamin K-dependent protein S and complement component C4b-binding protein
    • DOI 10.1073/pnas.78.4.2512
    • Dahlback B, Stenflo J. High molecular weight complex in human plasma between vitamin K-dependent protein S and complement component C4b-binding protein. Proc Natl Acad Sci U S A. 1981;78(4):2512-2516. (Pubitemid 11048838)
    • (1981) Proceedings of the National Academy of Sciences of the United States of America , vol.78 , Issue.4 II , pp. 2512-2516
    • Dahlback, B.1    Stenflo, J.2
  • 13
    • 0842328856 scopus 로고    scopus 로고
    • Coagulation, inflammation, and apoptosis: Different roles for protein S and the protein S-C4b binding protein complex
    • DOI 10.1182/blood-2003-05-1551
    • Rezende SM, Simmonds RE, Lane DA. Coagulation, inflammation, and apoptosis: different roles for protein S and the protein S-C4b binding protein complex. Blood. 2004;103(4):1192-1201. (Pubitemid 38168627)
    • (2004) Blood , vol.103 , Issue.4 , pp. 1192-1201
    • Rezende, S.M.1    Simmonds, R.E.2    Lane, D.A.3
  • 14
    • 34447540033 scopus 로고    scopus 로고
    • The tale of protein S and C4b-binding protein, story of affection
    • DOI 10.1160/TH07-04-0269
    • Dahlback B. The tale of protein S and C4b-binding protein, a story of affection. Thromb Haemost. 2007; 98(1):90-96. (Pubitemid 47074183)
    • (2007) Thrombosis and Haemostasis , vol.98 , Issue.1 , pp. 90-96
    • Dahlback, B.1
  • 15
    • 42449084553 scopus 로고    scopus 로고
    • Re-evaluation of the role of the protein SC4b binding protein complex in activated protein C-catalyzed factor Va-inactivation
    • Maurissen LF, Thomassen MC, Nicolaes GA, et al. Re-evaluation of the role of the protein SC4b binding protein complex in activated protein C-catalyzed factor Va-inactivation. Blood. 2008; 111(6):3034-3041.
    • (2008) Blood , vol.111 , Issue.6 , pp. 3034-3041
    • Maurissen, L.F.1    Thomassen, M.C.2    Nicolaes, G.A.3
  • 16
    • 29244445116 scopus 로고    scopus 로고
    • Post-translational modifications in proteins involved in blood coagulation
    • DOI 10.1111/j.1538-7836.2005.01478.x
    • Hansson K, Stenflo J. Post-translational modifications in proteins involved in blood coagulation. J Thromb Haemost. 2005;3(12):2633-2648. (Pubitemid 41819790)
    • (2005) Journal of Thrombosis and Haemostasis , vol.3 , Issue.12 , pp. 2633-2648
    • Hansson, K.1    Stenflo, J.2
  • 17
    • 0025604979 scopus 로고
    • Gamma-carboxylated isoforms of recombinant human protein S with different biologic properties
    • Grinnell BW, Walls JD, Marks C, et al. Gamma-carboxylated isoforms of recombinant human protein S with different biologic properties. Blood. 1990;76(12):2546-2554.
    • (1990) Blood , vol.76 , Issue.12 , pp. 2546-2554
    • Grinnell, B.W.1    Walls, J.D.2    Marks, C.3
  • 18
  • 19
    • 0031137254 scopus 로고    scopus 로고
    • A theoretical model for the Gla-TSR-EGF-1 region of the anticoagulant cofactor protein S: From biostructural pathology to species-specific cofactor activity
    • Villoutreix BO, Teleman O, Dahlback B. A theoretical model for the Gla-TSR-EGF-1 region of the anticoagulant cofactor protein S: from biostructural pathology to species-specific cofactor activity. J Comput Aided Mol Des. 1997;11(3): 293-304. (Pubitemid 127506737)
    • (1997) Journal of Computer-Aided Molecular Design , vol.11 , Issue.3 , pp. 293-304
    • Villoutreix, B.O.1    Teleman, O.2    Dahlback, B.3
  • 20
    • 0028110027 scopus 로고
    • The mechanism of inactivation of human factor V and human factor Va by activated protein C
    • Kalafatis M, Rand MD, Mann KG. The mechanism of inactivation of human factor V and human factor Va by activated protein C. J Biol Chem. 1994;269(50):31869-31880. (Pubitemid 24379561)
    • (1994) Journal of Biological Chemistry , vol.269 , Issue.50 , pp. 31869-31880
    • Kalafatis, M.1    Rand, M.D.2    Mann, K.G.3
  • 21
    • 0028810678 scopus 로고
    • Effects of protein S and factor Xa on peptide bond cleavages during inactivation of factor Va and factor VaR506Q by activated protein C
    • Rosing J, Hoekema L, Nicolaes GA, et al. Effects of protein S and factor Xa on peptide bond cleavages during inactivation of factor Va and factor VaR506Q by activated protein C. J Biol Chem. 1995;270(46):27852-27858.
    • (1995) J Biol Chem , vol.270 , Issue.46 , pp. 27852-27858
    • Rosing, J.1    Hoekema, L.2    Nicolaes, G.A.3
  • 22
    • 0043092166 scopus 로고    scopus 로고
    • Importance of Protein S and Phospholipid for Activated Protein C-mediated Cleavages in Factor Va
    • DOI 10.1074/jbc.M303829200
    • Norstrom EA, Steen M, Tran S, Dahlback B. Importance of protein S and phospholipid for activated protein C-mediated cleavages in factor Va. J Biol Chem. 2003;278(27):24904-24911. (Pubitemid 37548650)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.27 , pp. 24904-24911
    • Norstrom, E.A.1    Steen, M.2    Tran, S.3    Dahlback, B.4
  • 23
    • 0030770425 scopus 로고    scopus 로고
    • Protein S alters the active site location of activated protein C above the membrane surface. A fluorescence resonance energy transfer study of topography
    • DOI 10.1074/jbc.272.40.25013
    • Yegneswaran S,Wood GM, Esmon CT, JohnsonAE. Protein S alters the active site location of activated protein C above the membrane surface: a fluorescence resonance energy transfer study of topography. J Biol Chem. 1997;272(40):25013- 25021. (Pubitemid 27415681)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.40 , pp. 25013-25021
    • Yegneswaran, S.1    Wood, G.M.2    Esmon, C.T.3    Johnson, A.E.4
  • 24
    • 73049099489 scopus 로고    scopus 로고
    • Novel APC-cleavage sites in FVa provide insights into mechanisms of action of APC and its cofactor protein S
    • Tran S, Dahlback B. Novel APC-cleavage sites in FVa provide insights into mechanisms of action of APC and its cofactor protein S. J Thromb Haemost. 2010;8(1):129-136.
    • (2010) J Thromb Haemost , vol.8 , Issue.1 , pp. 129-136
    • Tran, S.1    Dahlback, B.2
  • 25
    • 0025303669 scopus 로고
    • Characterization of functionally important domains in human vitamin K-dependent protein S using monoclonal antibodies
    • Dahlback B, Hildebrand B, Malm J. Characterization of functionally important domains in human vitamin K-dependent protein S using monoclonal antibodies. J Biol Chem. 1990;265(14):8127-8135.
    • (1990) J Biol Chem , vol.265 , Issue.14 , pp. 8127-8135
    • Dahlback, B.1    Hildebrand, B.2    Malm, J.3
  • 26
    • 0037441591 scopus 로고    scopus 로고
    • Deletion or replacement of the second EGF-like domain of protein S results in loss of APC cofactor activity
    • DOI 10.1182/blood-2002-08-2353
    • Mille-Baker B, Rezende SM, Simmonds RE, et al. Deletion or replacement of the second EGF-like domain of protein S results in loss of APC cofactor activity. Blood. 2003;101(4):1416-1418. (Pubitemid 36182514)
    • (2003) Blood , vol.101 , Issue.4 , pp. 1416-1418
    • Mille-Baker, B.1    Rezende, S.M.2    Simmonds, R.E.3    Mason, P.J.4    Lane, D.A.5    Laffan, M.A.6
  • 28
    • 0032538548 scopus 로고    scopus 로고
    • Amino acid residues in thrombin-sensitive region and first epidermal growth factor domain of vitamin K-dependent protein S determining specificity of the activated protein C cofactor function
    • DOI 10.1074/jbc.273.42.27449
    • He X, Shen L, Villoutreix BO, Dahlback B. Amino acid residues in thrombin-sensitive region and first epidermal growth factor domain of vitamin K-dependent protein S determining specificity of the activated protein C cofactor function. J Biol Chem. 1998;273(42):27449-27458. (Pubitemid 28500463)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.42 , pp. 27449-27458
    • He, X.1    Shen, L.2    Villoutreix, B.O.3    Dahlback, B.4
  • 29
    • 11144240514 scopus 로고    scopus 로고
    • The gamma-carboxyglutamic acid domain of anticoagulant protein S is involved in activated protein C cofactor activity, independently of phospholipid binding
    • DOI 10.1182/blood-2004-06-2176
    • Saller F, Villoutreix BO, Amelot A, et al. The gamma-carboxyglutamic acid domain of anticoagulant protein S is involved in activated protein C cofactor activity, independently of phospholipid binding. Blood. 2005;105(1):122-130. (Pubitemid 40053073)
    • (2005) Blood , vol.105 , Issue.1 , pp. 122-130
    • Saller, F.1    Villoutreix, B.O.2    Amelot, A.3    Kaabache, T.4    Le, B.B.F.5    Aiach, M.6    Gandrille, S.7    Borgel, D.8
  • 30
    • 77954707351 scopus 로고    scopus 로고
    • Activated protein C cofactor function of protein S: A critical role for Asp95 in the EGF1-like domain
    • Andersson HM, Arantes MJ, Crawley JT, et al. Activated protein C cofactor function of protein S: a critical role for Asp95 in the EGF1-like domain. Blood. 2010;115(23):4878-4885.
    • (2010) Blood , vol.115 , Issue.23 , pp. 4878-4885
    • Andersson, H.M.1    Arantes, M.J.2    Crawley, J.T.3
  • 31
    • 0346272820 scopus 로고    scopus 로고
    • In vitro high level protein S expression after modification of protein S cDNA
    • Rezende SM, Razzari C, Simmonds RE. In vitro high level protein S expression after modification of protein S cDNA. Thromb Haemost. 2003;90(6): 1214-1215. (Pubitemid 38004446)
    • (2003) Thrombosis and Haemostasis , vol.90 , Issue.6 , pp. 1214-1215
    • Rezende, S.M.1    Razzari, C.2    Simmonds, R.E.3
  • 32
    • 12644315029 scopus 로고
    • Proteolytic enzymes in coagulation, fibrinolysis, and complement activation. Part A
    • San Diego, CA: Academic Press
    • Lorand L, Mann KG. Proteolytic enzymes in coagulation, fibrinolysis, and complement activation. Part A. In: Mammalian Blood Coagulation Factors and Inhibitors. San Diego, CA: Academic Press; 1993.
    • (1993) Mammalian Blood Coagulation Factors and Inhibitors
    • Lorand, L.1    Mann, K.G.2
  • 33
    • 43749109436 scopus 로고    scopus 로고
    • Effects of prothrombin on the individual activated protein C-mediated cleavages of coagulation factor Va
    • Tran S, Norstrom E, Dahlback B. Effects of prothrombin on the individual activated protein C-mediated cleavages of coagulation factor Va. J Biol Chem. 2008;283(11):6648-6655.
    • (2008) J Biol Chem , vol.283 , Issue.11 , pp. 6648-6655
    • Tran, S.1    Norstrom, E.2    Dahlback, B.3
  • 34
    • 70350435294 scopus 로고    scopus 로고
    • Mouse recombinant protein C variants with enhanced membrane affinity and hyper-anticoagulant activity in mouse plasma
    • Krisinger MJ, Guo LJ, Salvagno GL, et al. Mouse recombinant protein C variants with enhanced membrane affinity and hyper-anticoagulant activity in mouse plasma. FEBS J. 2009;276(22): 6586-6602.
    • (2009) FEBS J , vol.276 , Issue.22 , pp. 6586-6602
    • Krisinger, M.J.1    Guo, L.J.2    Salvagno, G.L.3
  • 35
    • 0028290275 scopus 로고
    • Factor V and protein S as synergistic cofactors to activated protein C in degradation of factor VIIIa
    • Shen L, Dahlbäck B. Factor V and protein S as synergistic cofactors to activated protein C in degradation of factor VIIIa. J Biol Chem. 1994; 269(29):18735-18738. (Pubitemid 24226180)
    • (1994) Journal of Biological Chemistry , vol.269 , Issue.29 , pp. 18735-18738
    • Shen, L.1    Dahlback, B.2
  • 36
    • 0033854083 scopus 로고    scopus 로고
    • The second laminin G-type domain of protein S is indispensable for expression of full cofactor activity in activated protein C-catalysed inactivation of factor vet and factor VIIIa
    • Evenäs P, Garcia de Frutos P, Nicolaes GA, Dahlback B. The second laminin G-type domain of protein S is indispensable for expression of full cofactor activity in activated protein C-catalysed inactivation of factor Va and factor VIIIa. Thromb Haemost. 2000;84(2):271-277. (Pubitemid 30601474)
    • (2000) Thrombosis and Haemostasis , vol.84 , Issue.2 , pp. 271-277
    • Evenas, P.1    Garcia, D.F.P.2    Nicolaes, G.A.F.3    Dahlback, B.4
  • 37
    • 57749179741 scopus 로고    scopus 로고
    • Biochemical characterization of plasma-derived tissue factor pathway inhibitor: Post-translational modification of free, full-length form with particular reference to the sugar chain
    • Mori Y, Hamuro T, Nakashima T, et al. Biochemical characterization of plasma-derived tissue factor pathway inhibitor: post-translational modification of free, full-length form with particular reference to the sugar chain. J Thromb Haemost. 2009;7(1):111-120.
    • (2009) J Thromb Haemost , vol.7 , Issue.1 , pp. 111-120
    • Mori, Y.1    Hamuro, T.2    Nakashima, T.3
  • 38
    • 0035979361 scopus 로고    scopus 로고
    • Purified protein S contains multimeric forms with increased APC-independent anticoagulant activity
    • DOI 10.1021/bi002500a
    • Sere KM, Janssen MP, Willems GM, et al. Purified protein S contains multimeric forms with increased APC-independent anticoagulant activity. Biochemistry. 2001;40(30):8852-8860. (Pubitemid 32709518)
    • (2001) Biochemistry , vol.40 , Issue.30 , pp. 8852-8860
    • Sere, K.M.1    Janssen, M.P.2    Willems, G.M.3    Tans, G.4    Rosing, J.5    Hackeng, T.M.6
  • 39
    • 31444441809 scopus 로고    scopus 로고
    • Protein S multimers are generated in vitro and affect protein S structure-function analyses
    • DOI 10.1053/j.seminhematol.2005.11.027, PII S0037196305002349
    • Sere KM, Willems GM, Rosing J, Hackeng TM. Protein S multimers are generated in vitro and affect protein S structure-function analyses. Semin Hematol. 2006;43(1 suppl 1):S111-S120. (Pubitemid 43150513)
    • (2006) Seminars in Hematology , vol.43 , Issue.SUPPL. 1
    • Sere, K.M.1    Willems, G.M.2    Rosing, J.3    Hackeng, T.M.4
  • 40
    • 0019332589 scopus 로고
    • Regulation of activated protein C by a new protein: A possible function for bovine protein S
    • Walker FJ. Regulation of activated protein C by a new protein: a possible function for bovine protein S. J Biol Chem. 1980;255(12):5521-5524.
    • (1980) J Biol Chem , vol.255 , Issue.12 , pp. 5521-5524
    • Walker, F.J.1
  • 41
    • 33750380260 scopus 로고    scopus 로고
    • A single gamma-carboxyglutamic acid residue in a novel cysteine-rich secretory protein without propeptide
    • DOI 10.1021/bi061311a
    • Hansson K, Thamlitz AM, Furie B, Furie BC, Stenflo J. A single gamma-carboxyglutamic acid residue in a novel cysteine-rich secretory protein without propeptide. Biochemistry. 2006;45(42): 12828-12839. (Pubitemid 44630869)
    • (2006) Biochemistry , vol.45 , Issue.42 , pp. 12828-12839
    • Hansson, K.1    Thamlitz, A.-M.2    Furie, B.3    Furie, B.C.4    Stenflo, J.5
  • 42
    • 33745199727 scopus 로고    scopus 로고
    • Novel gamma-carboxyglutamic acid-containing peptides from the venom of Conus textile
    • Czerwiec E, Kalume DE, Roepstorff P, et al. Novel gamma-carboxyglutamic acid-containing peptides from the venom of Conus textile. FEBS J. 2006;273(12):2779-2788.
    • (2006) FEBS J , vol.273 , Issue.12 , pp. 2779-2788
    • Czerwiec, E.1    Kalume, D.E.2    Roepstorff, P.3
  • 43
    • 43449132997 scopus 로고    scopus 로고
    • Proline and gamma-carboxylated glutamate residues in matrix Gla protein are critical for binding of bone morphogenetic protein-4
    • DOI 10.1161/CIRCRESAHA.107.166124, PII 0000301220080509000011
    • Yao Y, Shahbazian A, Bostrom KI. Proline and gamma-carboxylated glutamate residues in matrix Gla protein are critical for binding of bone morphogenetic protein-4. Circ Res. 2008;102(9): 1065-1074. (Pubitemid 351667860)
    • (2008) Circulation Research , vol.102 , Issue.9 , pp. 1065-1074
    • Yao, Y.1    Shahbazian, A.2    Bostrom, K.I.3
  • 44
    • 54949125307 scopus 로고    scopus 로고
    • Growth arrest-specific gene 6 (GAS6): An outline of its role in haemostasis and inflammation
    • Fernandez-Fernandez L, Bellido-Martin L, Garcia de Frutos P. Growth arrest-specific gene 6 (GAS6): an outline of its role in haemostasis and inflammation. Thromb Haemost. 2008;100(4): 604-610.
    • (2008) Thromb Haemost , vol.100 , Issue.4 , pp. 604-610
    • Fernandez-Fernandez, L.1    Bellido-Martin, L.2    Garcia De Frutos, P.3


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