Primary breast cancer patients with high risk clinicopathologic features have high percentages of bone marrow epithelial cells with ALDH activity and CD44 +CD24 lo cancer stem cell phenotype

European Journal of Cancer

Volumn 47, Issue 10, 2011, Pages 1527-1536

  Reuben, James M ^a,b   Lee, Bang Ning ^a,b   Gao, Hui ^a,b   Cohen, Evan N ^a,b   Mego, Michel ^a,b,d   Giordano, Antonio ^a,b   Wang, Xuemei ^b   Lodhi, Ashutosh ^b   Krishnamurthy, Savitri ^b   Hortobagyi, Gabriel N ^b   Cristofanilli, Massimo ^b,c   Lucci, Anthony ^b   Woodward, Wendy A ^b  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b UNIVERSITY OF TEXAS   (United States)

^c FOX CHASE CANCER CENTER   (United States)

^d CANCER RESEARCH INSTITUTE   (Slovakia)

Author keywords

Breast cancer stem cells; Disseminated tumour cells; Neoadjuvant chemotherapy; Triple receptor negative

Indexed keywords

ALDEHYDE DEHYDROGENASE;

ARTICLE; BONE MARROW BIOPSY; BONE MARROW CELL; BREAST CANCER; CANCER ADJUVANT THERAPY; CANCER PATIENT; CANCER STEM CELL; CELL POPULATION; CLINICAL FEATURE; CONTROLLED STUDY; ENZYME ACTIVITY; EPITHELIUM CELL; FLOW CYTOMETRY; HIGH RISK PATIENT; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ADULT; AGED; ALDEHYDE DEHYDROGENASE; ANTIGENS, CD24; ANTIGENS, CD44; BONE MARROW CELLS; BREAST NEOPLASMS; EPITHELIAL CELLS; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MIDDLE AGED; NEOPLASTIC STEM CELLS; PHENOTYPE; PROSPECTIVE STUDIES; RISK;

EID: 79958852461     PISSN: 09598049     EISSN: 18790852     Source Type: Journal    
DOI: 10.1016/j.ejca.2011.01.011     Document Type: Article

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