-
1
-
-
68149112387
-
Mimicking the BH3 domain to kill cancer cells
-
Chonghaile, T. N. and Letai, A. (2008) Mimicking the BH3 domain to kill cancer cells Oncogene 27 (Suppl. 1) S149-S157
-
(2008)
Oncogene
, vol.27
, Issue.SUPPL. 1
-
-
Chonghaile, T.N.1
Letai, A.2
-
2
-
-
20444486559
-
An inhibitor of Bcl-2 family proteins induces regression of solid tumours
-
DOI 10.1038/nature03579
-
Oltersdorf, T., Elmore, S. W., Shoemaker, A. R., Armstrong, R. C., Augeri, D. J., Belli, B. A., Bruncko, M., Deckwerth, T. L., Dinges, J., Hajduk, P. J., Joseph, M. K., Kitada, S., Korsmeyer, S. J., Kunzer, A. R., Letai, A., Li, C., Mitten, M. J., Nettesheim, D. G., Ng, S., Nimmer, P. M., O'Connor, J. M., Oleksijew, A., Petros, A. M., Reed, J. C., Shen, W., Tahir, S. K., Thompson, C. B., Tomaselli, K. J., Wang, B., Wendt, M. D., Zhang, H., Fesik, S. W., and Rosenberg, S. H. (2005) An inhibitor of Bcl-2 family proteins induces regression of solid tumours Nature 435, 677-681 (Pubitemid 40825512)
-
(2005)
Nature
, vol.435
, Issue.7042
, pp. 677-681
-
-
Oltersdorf, T.1
Elmore, S.W.2
Shoemaker, A.R.3
Armstrong, R.C.4
Augeri, D.J.5
Belli, B.A.6
Bruncko, M.7
Deckwerth, T.L.8
Dinges, J.9
Hajduk, P.J.10
Joseph, M.K.11
Kitada, S.12
Korsmeyer, S.J.13
Kunzer, A.R.14
Letai, A.15
Li, C.16
Mitten, M.J.17
Nettesheim, D.G.18
Ng, S.19
Nimmer, P.M.20
O'Connor, J.M.21
Oleksijew, A.22
Petros, A.M.23
Reed, J.C.24
Shen, W.25
Tahir, S.K.26
Thompson, C.B.27
Tomaselli, K.J.28
Wang, B.29
Wendt, M.D.30
Zhang, H.31
Fesik, S.W.32
Rosenberg, S.H.33
more..
-
3
-
-
56249144184
-
Discovery of an orally bioavailable small molecule inhibitor of prosurvival B-cell lymphoma 2 proteins
-
Park, C. M., Bruncko, M., Adickes, J., Bauch, J., Ding, H., Kunzer, A., Marsh, K. C., Nimmer, P., Shoemaker, A. R., Song, X., Tahir, S. K., Tse, C., Wang, X., Wendt, M. D., Yang, X., Zhang, H., Fesik, S. W., Rosenberg, S. H., and Elmore, S. W. (2008) Discovery of an orally bioavailable small molecule inhibitor of prosurvival B-cell lymphoma 2 proteins J. Med. Chem. 51, 6902-6915
-
(2008)
J. Med. Chem.
, vol.51
, pp. 6902-6915
-
-
Park, C.M.1
Bruncko, M.2
Adickes, J.3
Bauch, J.4
Ding, H.5
Kunzer, A.6
Marsh, K.C.7
Nimmer, P.8
Shoemaker, A.R.9
Song, X.10
Tahir, S.K.11
Tse, C.12
Wang, X.13
Wendt, M.D.14
Yang, X.15
Zhang, H.16
Fesik, S.W.17
Rosenberg, S.H.18
Elmore, S.W.19
-
4
-
-
50349098706
-
Activity of the Bcl-2 family inhibitor ABT-263 in a panel of small cell lung cancer xenograft models
-
Shoemaker, A. R., Mitten, M. J., Adickes, J., Ackler, S., Refici, M., Ferguson, D., Oleksijew, A., O'Connor, J. M., Wang, B., Frost, D. J., Bauch, J., Marsh, K., Tahir, S. K., Yang, X., Tse, C., Fesik, S. W., Rosenberg, S. H., and Elmore, S. W. (2008) Activity of the Bcl-2 family inhibitor ABT-263 in a panel of small cell lung cancer xenograft models Clin. Cancer Res. 14, 3268-3277
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 3268-3277
-
-
Shoemaker, A.R.1
Mitten, M.J.2
Adickes, J.3
Ackler, S.4
Refici, M.5
Ferguson, D.6
Oleksijew, A.7
O'connor, J.M.8
Wang, B.9
Frost, D.J.10
Bauch, J.11
Marsh, K.12
Tahir, S.K.13
Yang, X.14
Tse, C.15
Fesik, S.W.16
Rosenberg, S.H.17
Elmore, S.W.18
-
5
-
-
44849112219
-
ABT-263: A potent and orally bioavailable Bcl-2 family inhibitor
-
Tse, C., Shoemaker, A. R., Adickes, J., Anderson, M. G., Chen, J., Jin, S., Johnson, E. F., Marsh, K. C., Mitten, M. J., Nimmer, P., Roberts, L., Tahir, S. K., Xiao, Y., Yang, X., Zhang, H., Fesik, S., Rosenberg, S. H., and Elmore, S. W. (2008) ABT-263: A potent and orally bioavailable Bcl-2 family inhibitor Cancer Res. 68, 3421-3428
-
(2008)
Cancer Res.
, vol.68
, pp. 3421-3428
-
-
Tse, C.1
Shoemaker, A.R.2
Adickes, J.3
Anderson, M.G.4
Chen, J.5
Jin, S.6
Johnson, E.F.7
Marsh, K.C.8
Mitten, M.J.9
Nimmer, P.10
Roberts, L.11
Tahir, S.K.12
Xiao, Y.13
Yang, X.14
Zhang, H.15
Fesik, S.16
Rosenberg, S.H.17
Elmore, S.W.18
-
6
-
-
77951442337
-
Acquired resistance to ABT-737 in lymphoma cells that up-regulate MCL-1 and BFL-1
-
Yecies, D., Carlson, N. E., Deng, J., and Letai, A. (2010) Acquired resistance to ABT-737 in lymphoma cells that up-regulate MCL-1 and BFL-1 Blood 115, 3304-3313
-
(2010)
Blood
, vol.115
, pp. 3304-3313
-
-
Yecies, D.1
Carlson, N.E.2
Deng, J.3
Letai, A.4
-
7
-
-
34249996230
-
L inhibitor ABT-737
-
DOI 10.1038/sj.onc.1210166, PII 1210166
-
Lin, X., Morgan-Lappe, S., Huang, X., Li, L., Zakula, D. M., Vernetti, L. A., Fesik, S. W., and Shen, Y. (2007) 'Seed' analysis of off-target siRNAs reveals an essential role of Mcl-1 in resistance to the small-molecule Bcl-2/Bcl-XL inhibitor ABT-737 Oncogene 26, 3972-3979 (Pubitemid 46884293)
-
(2007)
Oncogene
, vol.26
, Issue.27
, pp. 3972-3979
-
-
Lin, X.1
Morgan-Lappe, S.2
Huang, X.3
Li, L.4
Zakula, D.M.5
Vernetti, L.A.6
Fesik, S.W.7
Shen, Y.8
-
8
-
-
33846674886
-
Mcl-1 down-regulation potentiates ABT-737 lethality by cooperatively inducing Bak activation and Bax translocation
-
DOI 10.1158/0008-5472.CAN-06-3964
-
Chen, S., Dai, Y., Harada, H., Dent, P., and Grant, S. (2007) Mcl-1 down-regulation potentiates ABT-737 lethality by cooperatively inducing Bak activation and Bax translocation Cancer Res. 67, 782-791 (Pubitemid 46192219)
-
(2007)
Cancer Research
, vol.67
, Issue.2
, pp. 782-791
-
-
Chen, S.1
Dai, Y.2
Harada, H.3
Dent, P.4
Grant, S.5
-
9
-
-
33750834023
-
The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized
-
DOI 10.1016/j.ccr.2006.08.027, PII S1535610806002911
-
van Delft, M. F., Wei, A. H., Mason, K. D., Vandenberg, C. J., Chen, L., Czabotar, P. E., Willis, S. N., Scott, C. L., Day, C. L., Cory, S., Adams, J. M., Roberts, A. W., and Huang, D. C. (2006) The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized Cancer Cell 10, 389-399 (Pubitemid 44711953)
-
(2006)
Cancer Cell
, vol.10
, Issue.5
, pp. 389-399
-
-
Van Delft, M.F.1
Wei, A.H.2
Mason, K.D.3
Vandenberg, C.J.4
Chen, L.5
Czabotar, P.E.6
Willis, S.N.7
Scott, C.L.8
Day, C.L.9
Cory, S.10
Adams, J.M.11
Roberts, A.W.12
Huang, D.C.S.13
-
10
-
-
23744486988
-
NFκB activity, function, and target-gene signatures in primary mediastinal large B-cell lymphoma and diffuse large B-cell lymphoma subtypes
-
DOI 10.1182/blood-2004-12-4901
-
Feuerhake, F., Kutok, J. L., Monti, S., Chen, W., LaCasce, A. S., Cattoretti, G., Kurtin, P., Pinkus, G. S., de Leval, L., Harris, N. L., Savage, K. J., Neuberg, D., Habermann, T. M., Dalla-Favera, R., Golub, T. R., Aster, J. C., and Shipp, M. A. (2005) NF'B activity, function, and target-gene signatures in primary mediastinal large B-cell lymphoma and diffuse large B-cell lymphoma subtypes Blood 106, 1392-1399 (Pubitemid 41129606)
-
(2005)
Blood
, vol.106
, Issue.4
, pp. 1392-1399
-
-
Feuerhake, F.1
Kutok, J.L.2
Monti, S.3
Chen, W.4
LaCasce, A.S.5
Cattoretti, G.6
Kurtin, P.7
Pinkus, G.S.8
De Levai, L.9
Harris, N.L.10
Savage, K.J.11
Neuberg, D.12
Habermann, T.M.13
Dalla-Favera, R.14
Golub, T.R.15
Aster, J.C.16
Shipp, M.A.17
-
11
-
-
20144382754
-
Molecular profiling of diffuse large B-cell lymphoma identifies robust subtypes including one characterized by host inflammatory response
-
DOI 10.1182/blood-2004-07-2947
-
Monti, S., Savage, K. J., Kutok, J. L., Feuerhake, F., Kurtin, P., Mihm, M., Wu, B., Pasqualucci, L., Neuberg, D., Aguiar, R. C., Dal Cin, P., Ladd, C., Pinkus, G. S., Salles, G., Harris, N. L., Dalla-Favera, R., Habermann, T. M., Aster, J. C., Golub, T. R., and Shipp, M. A. (2005) Molecular profiling of diffuse large B-cell lymphoma identifies robust subtypes including one characterized by host inflammatory response Blood 105, 1851-1861 (Pubitemid 40731764)
-
(2005)
Blood
, vol.105
, Issue.5
, pp. 1851-1861
-
-
Monti, S.1
Savage, K.J.2
Kutok, J.L.3
Feuerhake, F.4
Kurtin, P.5
Mihm, M.6
Wu, B.7
Pasqualucci, L.8
Neuberg, D.9
Aguiar, R.C.T.10
Cin, P.D.11
Ladd, C.12
Pinkus, G.S.13
Salles, G.14
Harris, N.L.15
Dalla-Favera, R.16
Habermann, T.M.17
Aster, J.C.18
Golub, T.R.19
Shipp, M.A.20
more..
-
12
-
-
33645279862
-
Molecular diagnosis of Burkitt's lymphoma
-
Dave, S. S., Fu, K., Wright, G. W., Lam, L. T., Kluin, P., Boerma, E. J., Greiner, T. C., Weisenburger, D. D., Rosenwald, A., Ott, G., Muller-Hermelink, H. K., Gascoyne, R. D., Delabie, J., Rimsza, L. M., Braziel, R. M., Grogan, T. M., Campo, E., Jaffe, E. S., Dave, B. J., Sanger, W., Bast, M., Vose, J. M., Armitage, J. O., Connors, J. M., Smeland, E. B., Kvaloy, S., Holte, H., Fisher, R. I., Miller, T. P., Montserrat, E., Wilson, W. H., Bahl, M., Zhao, H., Yang, L., Powell, J., Simon, R., Chan, W. C., and Staudt, L. M. (2006) Molecular diagnosis of Burkitt's lymphoma N. Engl. J. Med. 354, 2431-2442
-
(2006)
N. Engl. J. Med.
, vol.354
, pp. 2431-2442
-
-
Dave, S.S.1
Fu, K.2
Wright, G.W.3
Lam, L.T.4
Kluin, P.5
Boerma, E.J.6
Greiner, T.C.7
Weisenburger, D.D.8
Rosenwald, A.9
Ott, G.10
Muller-Hermelink, H.K.11
Gascoyne, R.D.12
Delabie, J.13
Rimsza, L.M.14
Braziel, R.M.15
Grogan, T.M.16
Campo, E.17
Jaffe, E.S.18
Dave, B.J.19
Sanger, W.20
Bast, M.21
Vose, J.M.22
Armitage, J.O.23
Connors, J.M.24
Smeland, E.B.25
Kvaloy, S.26
Holte, H.27
Fisher, R.I.28
Miller, T.P.29
Montserrat, E.30
Wilson, W.H.31
Bahl, M.32
Zhao, H.33
Yang, L.34
Powell, J.35
Simon, R.36
Chan, W.C.37
Staudt, L.M.38
more..
-
13
-
-
34548161868
-
Downregulation of Bfl-1 protein expression sensitizes malignant B cells to apoptosis
-
DOI 10.1038/sj.onc.1210363, PII 1210363
-
Brien, G., Trescol-Biemont, M. C., and Bonnefoy-Berard, N. (2007) Downregulation of Bfl-1 protein expression sensitizes malignant B cells to apoptosis Oncogene 26, 5828-5832 (Pubitemid 47312815)
-
(2007)
Oncogene
, vol.26
, Issue.39
, pp. 5828-5832
-
-
Brien, G.1
Trescol-Biemont, M.-C.2
Bonnefoy-Berard, N.3
-
14
-
-
41149117550
-
The eleven-year switch of peptide aptamers
-
Colas, P. (2008) The eleven-year switch of peptide aptamers J. Biol. 7, 2
-
(2008)
J. Biol.
, vol.7
, pp. 2
-
-
Colas, P.1
-
15
-
-
0029876415
-
Genetic selection of peptide aptamers that recognize and inhibit cyclin-dependent kinase 2
-
DOI 10.1038/380548a0
-
Colas, P., Cohen, B., Jessen, T., Grishina, I., McCoy, J., and Brent, R. (1996) Genetic selection of peptide aptamers that recognize and inhibit cyclin-dependent kinase 2 Nature 380, 548-550 (Pubitemid 26110646)
-
(1996)
Nature
, vol.380
, Issue.6574
, pp. 548-550
-
-
Colas, P.1
Cohen, B.2
Jessen, T.3
Grishina, I.4
McCoy, J.5
Brent, R.6
-
16
-
-
0032564350
-
An artificial cell-cycle inhibitor isolated from a combinatorial library
-
DOI 10.1073/pnas.95.24.14272
-
Cohen, B. A., Colas, P., and Brent, R. (1998) An artificial cell-cycle inhibitor isolated from a combinatorial library Proc. Natl. Acad. Sci. U.S.A. 95, 14272-14277 (Pubitemid 28549357)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.24
, pp. 14272-14277
-
-
Cohen, B.A.1
Colas, P.2
Brent, R.3
-
17
-
-
0141733147
-
Sequence-specific peptide aptamers, interacting with the intracellular domain of the epidermal growth factor receptor, interfere with Stat3 activation and inhibit the growth of tumor cells
-
DOI 10.1074/jbc.M301629200
-
Buerger, C., Nagel-Wolfrum, K., Kunz, C., Wittig, I., Butz, K., Hoppe-Seyler, F., and Groner, B. (2003) Sequence-specific peptide aptamers, interacting with the intracellular domain of the epidermal growth factor receptor, interfere with Stat3 activation and inhibit the growth of tumor cells J. Biol. Chem. 278, 37610-37621 (Pubitemid 37175284)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.39
, pp. 37610-37621
-
-
Buerger, C.1
Nagel-Wolfrum, K.2
Kunz, C.3
Wittig, I.4
Butz, K.5
Hoppe-Seyler, F.6
Groner, B.7
-
18
-
-
3543070089
-
The interaction of specific peptide aptamers with the DNA binding domain and the dimerization domain of the transcription factor Stat3 inhibits transactivation and induces apoptosis in tumor cells
-
Nagel-Wolfrum, K., Buerger, C., Wittig, I., Butz, K., Hoppe-Seyler, F., and Groner, B. (2004) The interaction of specific peptide aptamers with the DNA binding domain and the dimerization domain of the transcription factor Stat3 inhibits transactivation and induces apoptosis in tumor cells Mol. Cancer Res. 2, 170-182 (Pubitemid 39030307)
-
(2004)
Molecular Cancer Research
, vol.2
, Issue.3
, pp. 170-182
-
-
Nagel-Wolfrum, K.1
Buerger, C.2
Wittig, I.3
Butz, K.4
Hoppe-Seyler, F.5
Groner, B.6
-
19
-
-
0033614968
-
Inhibition of mammalian cell proliferation by genetically selected peptide aptamers that functionally antagonize E2F activity
-
DOI 10.1038/sj.onc.1202825
-
Fabbrizio, E., Le Cam, L., Polanowska, J., Kaczorek, M., Lamb, N., Brent, R., and Sardet, C. (1999) Inhibition of mammalian cell proliferation by genetically selected peptide aptamers that functionally antagonize E2F activity Oncogene 18, 4357-4363 (Pubitemid 29392376)
-
(1999)
Oncogene
, vol.18
, Issue.30
, pp. 4357-4363
-
-
Fabbrizio, E.1
Le Cam, L.2
Polanowska, J.3
Kaczorek, M.4
Lamb, N.5
Brent, R.6
Sardet, C.7
-
20
-
-
0035807251
-
Peptide aptamers targeting the hepatitis B virus core protein: A new class of molecules with antiviral activity
-
DOI 10.1038/sj.onc.1204805
-
Butz, K., Denk, C., Fitscher, B., Crnkovic-Mertens, I., Ullmann, A., Schroder, C. H., and Hoppe-Seyler, F. (2001) Peptide aptamers targeting the hepatitis B virus core protein: A new class of molecules with antiviral activity Oncogene 20, 6579-6586 (Pubitemid 32980284)
-
(2001)
Oncogene
, vol.20
, Issue.45
, pp. 6579-6586
-
-
Butz, K.1
Denk, C.2
Fitscher, B.3
Crnkovic-Mertens, I.4
Ullmann, A.5
Schroder, C.H.6
Hoppe-Seyler, F.7
-
21
-
-
0035289707
-
Induction of apoptosis in cervical carcinoma cells by peptide aptamers that bind to the HPV-16 E7 oncoprotein
-
Nauenburg, S., Zwerschke, W., and Jansen-Durr, P. (2001) Induction of apoptosis in cervical carcinoma cells by peptide aptamers that bind to the HPV-16 E7 oncoprotein FASEB J. 15, 592-594
-
(2001)
FASEB J.
, vol.15
, pp. 592-594
-
-
Nauenburg, S.1
Zwerschke, W.2
Jansen-Durr, P.3
-
22
-
-
51449104047
-
A RasGAP SH3 peptide aptamer inhibits RasGAP-Aurora interaction and induces caspase-independent tumor cell death
-
Pamonsinlapatham, P., Hadj-Slimane, R., Raynaud, F., Bickle, M., Corneloup, C., Barthelaix, A., Lepelletier, Y., Mercier, P., Schapira, M., Samson, J., Mathieu, A. L., Hugo, N., Moncorge, O., Mikaelian, I., Dufour, S., Garbay, C., and Colas, P. (2008) A RasGAP SH3 peptide aptamer inhibits RasGAP-Aurora interaction and induces caspase-independent tumor cell death PLoS One 3, e2902
-
(2008)
PLoS One
, vol.3
, pp. 2902
-
-
Pamonsinlapatham, P.1
Hadj-Slimane, R.2
Raynaud, F.3
Bickle, M.4
Corneloup, C.5
Barthelaix, A.6
Lepelletier, Y.7
Mercier, P.8
Schapira, M.9
Samson, J.10
Mathieu, A.L.11
Hugo, N.12
Moncorge, O.13
Mikaelian, I.14
Dufour, S.15
Garbay, C.16
Colas, P.17
-
23
-
-
33645735686
-
A peptide aptamer to antagonize BCL-6 function
-
Chattopadhyay, A., Tate, S. A., Beswick, R. W., Wagner, S. D., and Ko Ferrigno, P. (2006) A peptide aptamer to antagonize BCL-6 function Oncogene 25, 2223-2233
-
(2006)
Oncogene
, vol.25
, pp. 2223-2233
-
-
Chattopadhyay, A.1
Tate, S.A.2
Beswick, R.W.3
Wagner, S.D.4
Ko Ferrigno, P.5
-
24
-
-
66349096574
-
Targeting LMO2 with a peptide aptamer establishes a necessary function in overt T-cell neoplasia
-
Appert, A., Nam, C. H., Lobato, N., Priego, E., Miguel, R. N., Blundell, T., Drynan, L., Sewell, H., Tanaka, T., and Rabbitts, T. (2009) Targeting LMO2 with a peptide aptamer establishes a necessary function in overt T-cell neoplasia Cancer Res. 69, 4784-4790
-
(2009)
Cancer Res.
, vol.69
, pp. 4784-4790
-
-
Appert, A.1
Nam, C.H.2
Lobato, N.3
Priego, E.4
Miguel, R.N.5
Blundell, T.6
Drynan, L.7
Sewell, H.8
Tanaka, T.9
Rabbitts, T.10
-
25
-
-
33846847966
-
Modulation of Nr-13 antideath activity by peptide aptamers
-
DOI 10.1038/sj.onc.1209832, PII 1209832
-
Nouvion, A. L., Thibaut, J., Lohez, O. D., Venet, S., Colas, P., Gillet, G., and Lalle, P. (2007) Modulation of Nr-13 antideath activity by peptide aptamers Oncogene 26, 701-710 (Pubitemid 46204249)
-
(2007)
Oncogene
, vol.26
, Issue.5
, pp. 701-710
-
-
Nouvion, A.-L.1
Thibaut, J.2
Lohez, O.D.3
Venet, S.4
Colas, P.5
Gillet, G.6
Lalle, P.7
-
26
-
-
0029092610
-
Correlation of two-hybrid affinity data with in vitro measurements
-
Estojak, J., Brent, R., and Golemis, E. A. (1995) Correlation of two-hybrid affinity data with in vitro measurements Mol. Cell. Biol. 15, 5820-5829
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 5820-5829
-
-
Estojak, J.1
Brent, R.2
Golemis, E.A.3
-
27
-
-
34147125167
-
Selection and characterization of large collections of peptide aptamers through optimized yeast two-hybrid procedures
-
Bickle, M. B., Dusserre, E., Moncorge, O., Bottin, H., and Colas, P. (2006) Selection and characterization of large collections of peptide aptamers through optimized yeast two-hybrid procedures Nat. Protoc. 1, 1066-1091
-
(2006)
Nat. Protoc.
, vol.1
, pp. 1066-1091
-
-
Bickle, M.B.1
Dusserre, E.2
Moncorge, O.3
Bottin, H.4
Colas, P.5
-
28
-
-
71049193105
-
C-terminal residues regulate localization and function of the antiapoptotic protein Bfl-1
-
Brien, G., Debaud, A. L., Robert, X., Oliver, L., Trescol-Biemont, M. C., Cauquil, N., Geneste, O., Aghajari, N., Vallette, F. M., Haser, R., and Bonnefoy-Berard, N. (2009) C-terminal residues regulate localization and function of the antiapoptotic protein Bfl-1 J. Biol. Chem. 284, 30257-30263
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 30257-30263
-
-
Brien, G.1
Debaud, A.L.2
Robert, X.3
Oliver, L.4
Trescol-Biemont, M.C.5
Cauquil, N.6
Geneste, O.7
Aghajari, N.8
Vallette, F.M.9
Haser, R.10
Bonnefoy-Berard, N.11
-
29
-
-
0029917541
-
Proapoptotic protein Bax heterodimerizes with Bcl-2 and homodimerizes with Bax via a novel domain (BH3) distinct from BH1 and BH2
-
DOI 10.1074/jbc.271.13.7440
-
Zha, H., Aime-Sempe, C., Sato, T., and Reed, J. C. (1996) Proapoptotic protein Bax heterodimerizes with Bcl-2 and homodimerizes with Bax via a novel domain (BH3) distinct from BH1 and BH2 J. Biol. Chem. 271, 7440-7444 (Pubitemid 26107015)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.13
, pp. 7440-7444
-
-
Zha, H.1
Aime-Sempe, C.2
Sato, T.3
Reed, J.C.4
-
30
-
-
0032543597
-
Functional dissection of Bfl-1, a Bcl-2 homolog: Anti-apoptosis, oncogene-cooperation and cell proliferation activities
-
D'Sa-Eipper, C. and Chinnadurai, G. (1998) Functional dissection of Bfl-1, a Bcl-2 homolog: Anti-apoptosis, oncogene-cooperation and cell proliferation activities Oncogene 16, 3105-3114 (Pubitemid 28318781)
-
(1998)
Oncogene
, vol.16
, Issue.24
, pp. 3105-3114
-
-
D'Sa-Eipper, C.1
Chinnadurai, G.2
-
31
-
-
0034646702
-
Structural basis of BFL-1 for its interaction with BAX and its anti- apoptotic action in mammalian and yeast cells
-
DOI 10.1074/jbc.275.15.11092
-
Zhang, H., Cowan-Jacob, S. W., Simonen, M., Greenhalf, W., Heim, J., and Meyhack, B. (2000) Structural basis of BFL-1 for its interaction with BAX and its anti-apoptotic action in mammalian and yeast cells J. Biol. Chem. 275, 11092-11099 (Pubitemid 30212751)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.15
, pp. 11092-11099
-
-
Zhang, H.1
Cowan-Jacob, S.W.2
Simonen, M.3
Greenhalf, W.4
Heim, J.5
Meyhack, B.6
-
32
-
-
31444444239
-
Short interfering RNA against the PDCD5 attenuates cell apoptosis and caspase-3 activity induced by Bax overexpression
-
DOI 10.1007/s10495-005-3134-y
-
Chen, L. N., Wang, Y., Ma, D. L., and Chen, Y. Y. (2006) Short interfering RNA against the PDCD5 attenuates cell apoptosis and caspase-3 activity induced by Bax overexpression Apoptosis 11, 101-111 (Pubitemid 43151648)
-
(2006)
Apoptosis
, vol.11
, Issue.1
, pp. 101-111
-
-
Chen, L.N.1
Wang, Y.2
Ma, D.L.3
Chen, Y.Y.4
-
33
-
-
49849094579
-
Gambogic acid is an antagonist of antiapoptotic Bcl-2 family proteins
-
Zhai, D., Jin, C., Shiau, C. W., Kitada, S., Satterthwait, A. C., and Reed, J. C. (2008) Gambogic acid is an antagonist of antiapoptotic Bcl-2 family proteins Mol. Cancer Ther. 7, 1639-1646
-
(2008)
Mol. Cancer Ther.
, vol.7
, pp. 1639-1646
-
-
Zhai, D.1
Jin, C.2
Shiau, C.W.3
Kitada, S.4
Satterthwait, A.C.5
Reed, J.C.6
-
34
-
-
39849108605
-
Bfl-1/A1 functions, similar to Mcl-1, as a selective tBid and Bak antagonist
-
DOI 10.1038/sj.onc.1210771, PII 1210771
-
Simmons, M. J., Fan, G., Zong, W. X., Degenhardt, K., White, E., and Gelinas, C. (2008) Bfl-1/A1 functions, similar to Mcl-1, as a selective tBid and Bak antagonist Oncogene 27, 1421-1428 (Pubitemid 351317460)
-
(2008)
Oncogene
, vol.27
, Issue.10
, pp. 1421-1428
-
-
Simmons, M.J.1
Fan, G.2
Zong, W.-X.3
Degenhardt, K.4
White, E.5
Gelinas, C.6
-
35
-
-
0037134488
-
Bax and Bak independently promote cytochrome c release from mitochondria
-
DOI 10.1074/jbc.M109939200
-
Degenhardt, K., Sundararajan, R., Lindsten, T., Thompson, C., and White, E. (2002) Bax and Bak independently promote cytochrome C release from mitochondria J. Biol. Chem. 277, 14127-14134 (Pubitemid 34968024)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.16
, pp. 14127-14134
-
-
Degenhardt, K.1
Sundararajan, R.2
Lindsten, T.3
Thompson, C.4
White, E.5
-
36
-
-
34548552660
-
Upregulation of bfl-1 is a potential mechanism of chemoresistance in B-cell chronic lymphocytic leukaemia
-
DOI 10.1038/sj.bjc.6603951, PII 6603951
-
Olsson, A., Norberg, M., Okvist, A., Derkow, K., Choudhury, A., Tobin, G., Celsing, F., Osterborg, A., Rosenquist, R., Jondal, M., and Osorio, L. M. (2007) Upregulation of bfl-1 is a potential mechanism of chemoresistance in B-cell chronic lymphocytic leukaemia Br. J. Cancer 97, 769-777 (Pubitemid 47396296)
-
(2007)
British Journal of Cancer
, vol.97
, Issue.6
, pp. 769-777
-
-
Olsson, A.1
Norberg, M.2
Okvist, A.3
Derkow, K.4
Choudhury, A.5
Tobin, G.6
Celsing, F.7
Osterborg, A.8
Rosenquist, R.9
Jondal, M.10
Osorio, L.M.11
-
37
-
-
77649320940
-
Peptide aptamers for small molecule drug discovery
-
Bardou, C., Borie, C., Bickle, M., Rudkin, B. B., and Colas, P. (2009) Peptide aptamers for small molecule drug discovery Methods Mol. Biol. 535, 373-388
-
(2009)
Methods Mol. Biol.
, vol.535
, pp. 373-388
-
-
Bardou, C.1
Borie, C.2
Bickle, M.3
Rudkin, B.B.4
Colas, P.5
|