Liposome-encapsulated dexamethasone attenuates ventilator-induced lung inflammation

British Journal of Pharmacology

Volumn 163, Issue 5, 2011, Pages 1048-1058

  Hegeman, M A ^a,b   Cobelens, P M ^a,b   Kamps, Jaam ^c   Hennus, M P ^b   Jansen, N J G ^b   Schultz, M J ^d   Van Vught, A J ^b   Molema, G ^c   Heijnen, C J ^a  

^a Laboratory of Neuroimmunology and Developmental Origins of Disease   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^d ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

dexamethasone liposomes; Fc receptor targeting; lung inflammation; mechanical ventilation; mouse; ventilator induced lung injury

Indexed keywords

DEXAMETHASONE; FC RECEPTOR; IMMUNOGLOBULIN G; INTERLEUKIN 1BETA; INTERLEUKIN 6; KERATINOCYTE DERIVED CHEMOKINE; LIPOSOME; MONOCYTE CHEMOTACTIC PROTEIN 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ARTIFICIAL VENTILATION; CELL INFILTRATION; CONTROLLED STUDY; DOWN REGULATION; DRUG DOSAGE FORM COMPARISON; DRUG TARGETING; ENCAPSULATION; GENE EXPRESSION; GRANULOCYTE; LUNG DISEASE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TIDAL VOLUME; VENTILATOR INDUCED LUNG INFLAMMATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; DEXAMETHASONE; DISEASE MODELS, ANIMAL; HEMODYNAMICS; IMMUNOGLOBULIN G; LIPOSOMES; LUNG; MALE; MICE; MICE, INBRED C57BL; PNEUMONIA, VENTILATOR-ASSOCIATED; RECEPTORS, IGG; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 79958831502     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2011.01314.x     Document Type: Article

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