Synthesis and comparative study of tuberculostatic activity of pyrrole-based hydrazones related to structural variations

Pharmacia

Volumn 57, Issue 1-4, 2010, Pages 3-14

  Georgieva, Maya ^a   Bijev, A ^a   Prodanova, P ^a  

^a UNIVERSITY OF CHEMICAL TECHNOLOGY AND METALLURGY   (Bulgaria)

Author keywords

Antituberculars; Carbohydrazides; Hydrazones; Pyrrole; Synthesis

Indexed keywords

DIETHYL 5 ((2 (2 (5 (4 BROMOPHENYL) 3 (ETHOXYCARBONYL) 2 METHYL 1H PYRROL 1 YL)ACETYL)HYDRAZONO)METHYL) 3 METHYL 1 H PYRROLE 2,4 DICARBOXYLATE; DIETHYL 5 ((2 (3 (5 (4 BROMOPHENYL) 3 (ETHOXYCARBONYL) 2 METHYL 1H PYRROLE 1 YL)PROPANOYL)HYDRAZONO)METHYL) 3 METHYL 1H PYRROLE 2,4 DICARBOXYLATE; ETHYL 1 (2 (2 ((1 ACETYL 1H INDOL 3 YL)METHYLENE)HYDRAZINYL) 2 OXOETHYL) 5 (4 CHLOROPHENYL) 2 METHYL 1H PYRROLE 3 CARBOXYLATE; ETHYL 1 (3 (2 ((1 ACETYL 1H INDOL 3 YL)METHYLENE)HYDRAZINYL) 3 OXOPROPYL) 5 (4 BROMOPHENYL) 2 METHYL 1H PYRROLE 3 CARBOXYLATE; ETHYL 1 (3 (2 ((1H PYRROL 2 YL)METHYLENE)HYDRAZINYL) 3 OXOPROPYL) 5 (4 BROMOPHENYL) 2 METHYL 1H PYRROLE 3 CARBOXYLATE; ETHYL 1 (3 (2 ((4 ACETYL 3,5 DIMETHYL 1H PYRROL 2 YL)METHYLENE)HYDRAZINYL) 3 OXOPROPYL) 5 (4 BROMOPHENYL) 2 METHYL 1H PYRROLE 3 CARBOXYLATE; ETHYL 1 (3 (2 BENZYLIDENEHYDRAZINYL) 3 OXOPROPYL) 5 (4 BROMOPHENYL) 2 METHYL 1H PYRROLE 3 CARBOXYLATE; ETHYL 4 ((2 (3 (5 (4 BROMOPHENYL) 3 (ETHOXYCARBONYL) 2 METHYL 1H PYRROL 1 YL)PROPANOYL)HYDRAZONO)METHYL) 3,5 DIMETHYL 1H PYRROLE 2 CARBOXYLATE; ETHYL 4 ((2 (3 (5 (4 CHLOROPHENYL) 3 (ETHOXYCARBONYL) 2 METHYL 1H PYRROL 1 YL)PROPANOYL) HYDRAZONO)METHYL) 3,5 DIMETHYL 1H PYRROLE 2 CARBOXYLATE; ETHYL 5 (4 BROMOPHENYL) 1 (2 (2 (2 HYDROXY 5 NITROBENZYLIDENE)HYDRAZINYL) 2 OXOETHYL) 2 METHYL 1H PYRROLE 3 CARBOXYLATE; ETHYL 5 (4 BROMOPHENYL) 1 (2 (2 (4 ETHOXY 4 OXOBUTAN 2 YLIDENE)HYDRAZINYL) 2 OXOETHYL) 2 METHYL 1H PYRROLE 3 CARBOXYLATE; ETHYL 5 (4 BROMOPHENYL) 1 (3 (2 ((4 (ETHOXYCARBONYL) 3,5 DIMETHYL 1H PYRROL 2 YL)METHYLENE) HYDRAZINYL) 3 OXOPROPYL) 2 METHYL 1H PYRROLE 3 CARBOXYLATE; ETHYL 5 (4 BROMOPHENYL) 1 (3 (2 (2 HYDROXY 5 NITROBENZYLIDENE)HYDRAZINYL) 3 OXOPROPYL) 2 METHYL 1H PYRROLE 3 CARBOXYLATE; ETHYL 5 (4 BROMOPHENYL) 1 (3 (2 (2 HYDROXYBENXYLIDENE)HYDRAZINYL) 3 OXOPROPYL) 2 METHY 1H PYRROLE 3 CARBOXYLATE; ETHYL 5 (4 BROMOPHENYL) 1 (3 (2 (4 ETHOXY 4 OXOBUTAN 2 YLIDENE)HYDRAZINYL) 3 OXOPROPYL) 2 METHYL 1H PYRROLE 3 CARBOXYLATE; ETHYL 5 (4 BROMOPHENYL) 1 (3 (2 (4 METHOXYBENZYLIDENE)HYDRAZINYL) 3 OXOPROPYL) 2 METHYL 1H PYRROLE 3 CARBOXYLATE; ETHYL 5 (4 BROMOPHENYL) 1 (3 HYDRAZINYL 3 OXOPROPYL) 2 METHYL 1H PYRROLE 3 CARBOXYLATE; ETHYL 5 (4 BROMOPHENYL) 2 METHYL 1 (3 (2 ((5 NITROFURAN 2 YL)METHYLENE)HYDRAZINYL) 3 OXOPROPYL) 1H PYRROLE 3 CARBOXYLATE; ETHYL 5 (4 BROMOPHENYL) 2 METHYL 1 (3 OXO 3 (2 (2 OXOINDOLIN 3 YLIDENE)HYDRAZINYL)PROPYL) 1H PYRROLE 3 CARBOXYLATE; ETHYL 5 (4 BROMOPHENYL) 2 METHYL 1 (3 OXO 3 (2 (PYRIDIN 3 YLMETHYLENE)HYDRAZINYL)PROPYL) 1H PYRROLE 3 CARBOXYLATE; ETHYL 5 (4 CHLOROPHENYL) 1 (2 (2 ((4 (ETHOXYCARBONYL) 3, 5 DIMETHYL 1H PYRROL 2 YL)METHYLENE) HYDRAZINYL) 2 OXOETHYL) 2 METHYL 1H PYRROLE 3 CARBOXYLATE; ETHYL 5 (4 CHLOROPHENYL) 1 (2 (2 (2 HYDROXY 5 NITROBENZYLIDENE)HYDRAZINYL) 2 OXOETHYL) 2 METHYL 1H PYRROLE 3 CARBOXYLATE; ETHYL 5 (4 CHLOROPHENYL) 1 (2 (2 (4 ETHOXY 4 OXOBUTAN 2 YLIDENE)HYDRAZINYL) 2 OXOETHYL) 2 METHYL 1H PYRROLE 3 CARBOXYLATE; ETHYL 5 (4 CHLOROPHENYL) 1 (3 (2 ((4 (ETHOXYCARBONYL) 3,5 DIMETHYL 1H PYRROL 2 YL)METHYLENE) HYDRAZINYL) 3 OXOPROPYL) 2 METHYL 1H PYRROLE 3 CARBOXYLATE; ETHYL 5 (4 CHOROPHENYL) 1 (3 (2 (2 HYDROXY 5 NITROBENZYLIDENE)HYDRAZINYL) 3 OXOPROPHYL) 2 METHYL 1H PYRROLE 3 CARBOXYLATE; HALOGEN; HYDRAZONE DERIVATIVE; PYRROLE DERIVATIVE; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL STRAIN; COMPARATIVE STUDY; DRUG ACTIVITY; DRUG EFFECT; DRUG SYNTHESIS; GROWTH INHIBITION; IN VITRO STUDY; MYCOBACTERIUM TUBERCULOSIS; STRUCTURE ACTIVITY RELATION; TUBERCULOSIS; TUBERCULOSTATIC ACTIVITY;

EID: 79958828989     PISSN: 04280296     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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