Polycystic ovary syndrome is associated with atherogenic changes in lipoprotein particle number and size independent of body weight

Clinical Endocrinology

Volumn 75, Issue 1, 2011, Pages 76-82

  Sidhwani, Seema ^a   Scoccia, Bert ^a   Sunghay, Shwetha ^a   Stephens Archer, Chantale N ^a   Mazzone, Theodore ^a   Sam, Susan ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN; HIGH DENSITY LIPOPROTEIN; LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; SEX HORMONE BINDING GLOBULIN; TESTOSTERONE; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN;

ADULT; ALCOHOL CONSUMPTION; ARTICLE; ATHEROGENESIS; BODY MASS; BODY WEIGHT; CARDIOVASCULAR RISK; CASE CONTROL STUDY; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; ETHNICITY; EXERCISE; FEMALE; HUMAN; INSULIN RESISTANCE; NUCLEAR MAGNETIC RESONANCE; OVARY POLYCYSTIC DISEASE; PARTICLE SIZE; PREDICTION; PRIORITY JOURNAL; TOBACCO; ATHEROSCLEROSIS; BLOOD; CHEMISTRY; COMORBIDITY; PHYSIOLOGY; POLYCYSTIC OVARY SYNDROME; YOUNG ADULT;

ADULT; ANDROGENS; ATHEROSCLEROSIS; BODY WEIGHT; COMORBIDITY; FEMALE; HUMANS; INSULIN RESISTANCE; LIPOPROTEINS; POLYCYSTIC OVARY SYNDROME; YOUNG ADULT;

EID: 79958822147     PISSN: 03000664     EISSN: 13652265     Source Type: Journal    
DOI: 10.1111/j.1365-2265.2011.04015.x     Document Type: Article

References (32)

1. Talbott, E., Clerici, A., Berga, S.L., et al. (1998) Adverse lipid and coronary heart disease risk profiles in young women with polycystic ovary syndrome: results of a case-control study. Journal of Clinical Epidemiology, 51, 415-422. (Pubitemid 28223308)
2. Legro, R.S., Kunselman, A.R., &, Dunaif, A., (2001) Prevalence and predictors of dyslipidemia in women with polycystic ovary syndrome. The American Journal of Medicine, 111, 607-613. (Pubitemid 34088070)
3. Conway, G.S., Agrawal, R., Betteridge, D.J., et al. (1992) Risk factors for coronary artery disease in lean and obese women with the polycystic ovary syndrome. Clinical Endocrinology, 37, 119-125.
4. Wild, R.A., Painter, P.C., Coulson, P.B., et al. (1985) Lipoprotein lipid concentrations and cardiovascular risk in women with polycystic ovary syndrome. The Journal of Clinical Endocrinology and Metabolism, 61, 946-951. (Pubitemid 16218495)
5. Azziz, R., Carmina, E., Dewailly, D., et al. (2006) Positions statement: criteria for defining polycystic ovary syndrome as a predominantly hyperandrogenic syndrome: an Androgen Excess Society guideline. The Journal of Clinical Endocrinology and Metabolism, 91, 4237-4245. (Pubitemid 44833391)
6. Diamanti-Kandarakis, E., Papavassiliou, A.G., Kandarakis, S.A., et al. (2007) Pathophysiology and types of dyslipidemia in PCOS. Trends in Endocrinology and Metabolism, 18, 280-285. (Pubitemid 47332216)
7. Gardner, C.D., Fortmann, S.P., &, Krauss, R.M., (1996) Association of small low-density lipoprotein particles with the incidence of coronary artery disease in men and women. The Journal of American Medical Association, 276, 875-881. (Pubitemid 26301606)
8. Lamarche, B., Tchernof, A., Moorjani, S., et al. (1997) Small, dense low-density lipoprotein particles as a predictor of the risk of ischemic heart disease in men. Prospective results from the Quebec Cardiovascular Study. Circulation, 95, 69-75. (Pubitemid 27029945)
9. Garvey, W.T., Kwon, S., Zheng, D., et al. (2003) Effects of insulin resistance and type 2 diabetes on lipoprotein subclass particle size and concentration determined by nuclear magnetic resonance. Diabetes, 52, 453-462. (Pubitemid 36173203)
10. Rizzo, M., Pernice, V., Frasheri, A., et al. (2009) Small, dense low-density lipoproteins (LDL) are predictors of cardio- and cerebro-vascular events in subjects with the metabolic syndrome. Clinical Endocrinology, 70, 870-875.
11. Griffin, B.A., Freeman, D.J., Tait, G.W., et al. (1994) Role of plasma triglyceride in the regulation of plasma low density lipoprotein (LDL) subfractions: relative contribution of small, dense LDL to coronary heart disease risk. Atherosclerosis, 106, 241-253. (Pubitemid 24188766)
12. Pirwany, I.R., Fleming, R., Greer, I.A., et al. (2001) Lipids and lipoprotein subfractions in women with PCOS: relationship to metabolic and endocrine parameters. Clinical Endocrinology, 54, 447-453. (Pubitemid 34204180)
13. Dejager, S., Pichard, C., Giral, P., et al. (2001) Smaller LDL particle size in women with polycystic ovary syndrome compared to controls. Clinical Endocrinology, 54, 455-462. (Pubitemid 34204181)
14. Berneis, K., Rizzo, M., Lazzarini, V., et al. (2007) Atherogenic lipoprotein phenotype and low-density lipoproteins size and subclasses in women with polycystic ovary syndrome. The Journal of Clinical Endocrinology and Metabolism, 92, 186-189. (Pubitemid 46067529)
15. Zawadzki, J., &, Dunaif, A., (1992) Diagnostic criteria for polycystic ovary syndrome towards a rational approach. In:, A. Dunaif, J.R. Givens, F.P. Haseltine, G.R. Merriam, eds. Polycystic Ovary Syndrome. Blackwell Scientific Publications, Boston, 377-384.
16. Wild, R.A., Vesely, S., Beebe, L., et al. (2005) Ferriman Gallwey self-scoring I: performance assessment in women with polycystic ovary syndrome. The Journal of Clinical Endocrinology and Metabolism, 90, 4112-4114. (Pubitemid 41058181)
17. Grundy, S.M., Cleeman, J.I., Daniels, S.R., et al. (2005) Diagnosis and management of the metabolic syndrome. An American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Executive summary. Cardiology in Review, 13, 322-327. (Pubitemid 41579599)
18. Friedewald, W.T., Levy, R.I., &, Fredrickson, D.S., (1972) Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clinical Chemistry, 18, 499-502.
19. Jeyarajah, E.J., Cromwell, W.C., &, Otvos, J.D., (2006) Lipoprotein particle analysis by nuclear magnetic resonance spectroscopy. Clinics in Laboratory Medicine, 26, 847-870. (Pubitemid 44716510)
20. Matthews, D.R., Hosker, J.P., Rudenski, A.S., et al. (1985) Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia, 28, 412-419. (Pubitemid 15018832)
21. El Harchaoui, K., Arsenault, B.J., Franssen, R., et al. (2009) High-density lipoprotein particle size and concentration and coronary risk. Annals of Internal Medicine, 150, 84-93.
22. Cheung, M.C., Brown, B.G., Wolf, A.C., et al. (1991) Altered particle size distribution of apolipoprotein A-I-containing lipoproteins in subjects with coronary artery disease. Journal of Lipid Research, 32, 383-394.
23. Freedman, D.S., Otvos, J.D., Jeyarajah, E.J., et al. (1998) Relation of lipoprotein subclasses as measured by proton nuclear magnetic resonance spectroscopy to coronary artery disease. Arteriosclerosis, Thrombosis, and Vascular Biology, 18, 1046-1053. (Pubitemid 28323588)
24. Watanabe, H., Soderlund, S., Soro-Paavonen, A., et al. (2006) Decreased high-density lipoprotein (HDL) particle size, prebeta-, and large HDL subspecies concentration in Finnish low-HDL families: relationship with intima-media thickness. Arteriosclerosis, Thrombosis, and Vascular Biology 26, 897-902. (Pubitemid 43732169)
25. Koba, S., Yokota, Y., Hirano, T., et al. (2008) Small LDL-cholesterol is superior to LDL-cholesterol for determining severe coronary atherosclerosis. Journal of Atherosclerosis and Thrombosis, 15, 250-260.
26. Rader, D.J., (2006) Molecular regulation of HDL metabolism and function: implications for novel therapies. The Journal of Clinical Investigation, 116, 3090-3100. (Pubitemid 44878620)
27. Blake, G.J., Otvos, J.D., Rifai, N., et al. (2002) Low-density lipoprotein particle concentration and size as determined by nuclear magnetic resonance spectroscopy as predictors of cardiovascular disease in women. Circulation, 106, 1930-1937. (Pubitemid 35176297)
28. Kuller, L., Arnold, A., Tracy, R., et al. (2002) Nuclear magnetic resonance spectroscopy of lipoproteins and risk of coronary heart disease in the cardiovascular health study. Arteriosclerosis, Thrombosis, and Vascular Biology, 22, 1175-1180. (Pubitemid 34764870)
29. Sam, S., Haffner, S., Davidson, M.H., et al. (2008) Relationship of abdominal visceral and subcutaneous adipose tissue to lipoprotein particle number and size in type 2 diabetes. Diabetes, 57, 2022-2027.
30. Elbers, J.M., Asscheman, H., Seidell, J.C., et al. (1997) Long-term testosterone administration increases visceral fat in female to male transsexuals. The Journal of Clinical Endocrinology and Metabolism, 82, 2044-2047. (Pubitemid 27287559)
31. Lovejoy, J.C., Bray, G.A., Bourgeois, M.O., et al. (1996) Exogenous androgens influence body composition and regional body fat distribution in obese postmenopausal women-a clinical research center study. The Journal of Clinical Endocrinology and Metabolism, 81, 2198-2203. (Pubitemid 26175947)
32. Ehrmann, D.A., (2005) Polycystic ovary syndrome. The New England Journal of Medicine, 352, 1223-1236.