Discovery of the membrane receptor for mitochondrial fission GTPase Drp1

Small GTPases

Volumn 2, Issue 3, 2011, Pages 167-172

  Otera, Hidenori ^a   Mihara, Katsuyoshi ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

Drp1; Fis1; GTPase; Mff; Mitochondrial fission

Indexed keywords

DYNAMIN RELATED PROTEIN 1; GUANOSINE TRIPHOSPHATASE; MEMBRANE RECEPTOR; OUTER MEMBRANE PROTEIN; PROTEIN FIS1; PROTEIN MFF; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; MAMMAL CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN HYDROLYSIS; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN MOTIF;

MAMMALIA;

EID: 79958819666     PISSN: 21541248     EISSN: 21541256     Source Type: Journal    
DOI: 10.4161/sgtp.2.3.16486     Document Type: Article

References (36)

1. Otera H, Mihara K. Molecular Mechanisms and Physiologic Function of Mitochondrial Dynamics. J Biochem 2011; 149:241-51; PMID: 21233142; DOI:10.1093/jb/mvr002.
2. Chen H, Chan DC. Mitochondrial dynamics-fusion, fission, movement and mitophagy-in neurodegenerative diseases. Hum Mol Genet 2009; 18: 169-76; PMID: 19808793; DOI:10.1093/hmg/ddp326.
3. Okamoto K, Shaw JM. Mitochondrial morphology and dynamics in yeast and multicellular eukaryotes. Annu Rev Genet 2005; 39:503-36; PMID: 16285870; DOI:10.1146/annurev.genet.38.072902.093019.
4. Smirnova E, Griparic L, Shurland DL, van der Bliek AM. Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells. Mol Biol Cell 2001; 12:2245-56; PMID: 11514614.
5. Yoon Y, Pitts KR, McNiven MA. Mammalian dynamin-like protein DLP1 tubulates membranes. Mol Biol Cell 2001; 12:2894-905; PMID: 11553726.
6. Ingerman E, Perkins EM, Marino M, Mears JA, McCaffery JM, Hinshaw JE, et al. Dnm1 forms spirals that are structurally tailored to fit mitochondria. J Cell Biol 2005; 170:1021-7; PMID: 16186251; DOI:10.1083/jcb.200506078.
7. Ishihara N, Nomura M, Jofuku A, Kato H, Suzuki SO, Masuda K, et al. Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice. Nat Cell Biol 2009; 11:958-66; PMID: 19578372; DOI:10.1038/ncb1907.
8. Wakabayashi J, Zhang Z, Wakabayashi N, Tamura Y, Fukaya M, Kensler TW, et al. The dynamin-related GTPase Drp1 is required for embryonic and brain development in mice. J Cell Biol 2009; 186:805-16; PMID: 19752021; DOI:10.1083/jcb.200903065.
9. Waterham HR, Koster J, van Roermund CW, Mooyer PA, Wanders RJ, Leonard JV. A lethal defect of mitochondrial and peroxisomal fission. N Engl J Med 2007; 356:1736-41; PMID: 17460227; DOI:10.1056/NEJMoa064436.
10. Frank S, Gaume B, Bergmann-Leitner ES, Leitner WW, Robert EG, Catez F, et al. The role of dynaminrelated protein 1, a mediator of mitochondrial fission, in apoptosis. Dev Cell 2001; 1:515-25; PMID: 11703942; DOI:10.1016/S1534-5807(01)00055-7.
11. Cassidy-Stone A, Chipuk JE, Ingerman E, Song C, Yoo C, Kuwana T, et al. Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization. Dev Cell 2008; 14:193-204; PMID: 18267088; DOI:10.1016/j.devcel. 2007.11.019.
12. Lackner LL, Horner JS, Nunnari J. Mechanistic analysis of a dynamin effector. Science 2009; 325:874-7; PMID: 19679814; DOI:10.1126/science.1176921.
13. Mears JA, Lackner LL, Fang S, Ingerman E, Nunnari J, Hinshaw JE. Conformational changes in Dnm1 support a contractile mechanism for mitochondrial fission. Nat Struct Mol Biol 2011; 18:20-6; PMID: 21170049; DOI:10.1038/nsmb.1949.
14. Lackner LL, Nunnari JM. The molecular mechanism and cellular functions of mitochondrial division. Biochim Biophys Acta 2009; 1792:1138-44.
15. Koirala S, Bui HT, Schubert HL, Eckert DM, Hill CP, Kay MS, et al. Molecular architecture of a dynamin adaptor: implications for assembly of mitochondrial fission complexes. J Cell Biol 2010; 191:1127-39; PMID: 21149566; DOI:10.1083/jcb.201005046.
16. Gandre-Babbe S, van der Bliek AM. The Novel Tail-anchored Membrane Protein Mff Controls Mitochondrial and Peroxisomal Fission in Mammalian Cells. Mol Biol Cell 2008; 19:2402-12; PMID: 18353969; DOI:10.1091/mbc.E07-12-1287.
17. Otera H, Wang C, Cleland MM, Setoguchi K, Yokota S, Youle RJ, et al. Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells. J Cell Biol 2010; 191:1141-58; PMID: 21149567; DOI:10.1083/jcb.201007152.
18. Naylor K, Ingerman E, Okreglak V, Marino M, Hinshaw JE, Nunnari J. Mdv1 interacts with assembled dnm1 to promote mitochondrial division. J Biol Chem 2006; 281:2177-83; PMID: 16272155; DOI:10.1074/jbc.M507943200.
19. Yoon Y, Krueger EW, Oswald BJ, McNiven MA. The mitochondrial protein hFis1 regulates mitochondrial fission in mammalian cells through an interaction with the dynamin-like protein DLP1. Mol Cell Biol 2003; 23:5409-20; PMID: 12861026; DOI:10.1128/MCB.23.15.5409-20.2003.
20. Palmer CS, Osellame LD, Laine D, Koutsopoulos OS, Frazier AE, Ryan MT. MiD49 and MiD51, new components of the mitochondrial fission machinery. EMBO Rep published online 21 April 2011; PMID: 21508961.
21. Karbowski M, Jeong SY, Youle RJ. Endophilin B1 is required for the maintenance of mitochondrial morphology. J Cell Biol 2004; 166:1027-39; PMID: 15452144; DOI:10.1083/jcb.200407046.
22. Suen DF, Norris KL, Youle RJ. Mitochondrial dynamics and apoptosis. Genes Dev 2008; 22:1577-90; PMID: 18559474; DOI:10.1101/gad.1658508.
23. Benard G, Karbowski M. Mitochondrial fusion and division: regulation and role in cell viability. Semin Cell Dev Biol 2009; 20:365-74; PMID: 19530306; DOI:10.1016/j.semcdb.2008.12.012.
24. Stojanovski D, Koutsopoulos OS, Okamoto K, Ryan MT. Levels of human Fis1 at the mitochondrial outer membrane regulate mitochondrial morphology. J Cell Sci 2004; 117:1201-10; PMID: 14996942; DOI:10.1242/jcs.01058.
25. James DI, Parone PA, Mattenberger Y, Martinou JC. hFis1, a novel component of mammalian mitochondrial fission machinery. J Biol Chem 2003; 278:36373-9; PMID: 12783892; DOI:10.1074/jbc. M303758200.
26. Twig G, Elorza A, Molina AJ, Mohamed H, Wikstrom JD, Walzer G, et al. Fission and selective fusion govern mitochondrial segregation and elimination by autophagy. EMBO J 2008; 27:433-46; PMID: 18200046; DOI:10.1038/sj.emboj.7601963.
27. Arirol E, James D, Huber D, Marchetto A, Vergani L, Martinou JC, et al. The mitochondrial fission protein hFis1 requires the endoplasmic reticulum gateway to induce apoptosis. Mol Biol Cell 2006; 11:4593-605; PMID: 16914522.
28. Iwasawa R, Mahul-Mellier AL, Datler C, Pazarentzos E, Grimm S. Fis1 and Bap31 bridge the mitochondria-ER interface to establish a platform for apoptosis induction. EMBO J 2011; 30:556-68; PMID: 21183955; DOI:10.1038/emboj.2010.346.
29. de Brito OM, Scorrano L. Mitofusin 2 tethers endoplasmic reticulum to mitochondria. Nature 2008; 456:605-10; PMID: 19052620; DOI:10.1038/nature07534.
30. Koch A, Yoon Y, Bonekamp MA, McNiven MA, Schrader M. A role for Fis1 in both mitochondrial and peroixisomal fission in mammalian cells. Mol Biol Cell 2005; 16:5077-86; PMID: 16107562; DOI:10.1091/mbc.E05-02-0159.
31. Schrader M. Shared components of mitochondrial and peroxisomal division. Biochem. Biophys. Acta 2006; 1763:531-41.
32. Neuspiel M, Schauss AC, Braschi E, Zunino R, Rippstein P, Rachubinski RA, et al. Cargo-selected transport from the mitochondria to peroxisomes is mediated by vesicular carriers. Curr Biol 2008; 18:102-8; PMID: 18207745; DOI:10.1016/j. cub.2007.12.038.
33. Wriessnegger T, Gübitz G, Leitner E, Ingolic E, Cregg J, de la Cruz BJ, et al. Lipid composition of peroxisomes from the yeast Pichia passtoris grown on different carbon sources. Biochim Biophys Acta 2007; 1771:455-61.
34. Ma C, Agrawal G, Subramani S. Peroxisome assembly: matrix and membrne protein biogenesis. J Cell Biol 2011; 193:7-16; PMID: 21464226; DOI:10.1083/jcb.201010022.
35. Twig G, Hyde B, Shirihai OS. Mitochondrial fusion, fission and autophagy as a quality control axis: the bioenergetic view. Biochim Biophys Acta 2008; 1777:1092-7.
36. Gomes LC, Scorrano L. High levels of Fis1, a profission mitochondrial protein, trigger autophagy. Biochim Biophys Acta 2008; 1777:860-6.