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Volumn 62, Issue 2, 2011, Pages 215-224

A highly immunogenic recombinant and truncated protein of the secreted aspartic proteases family (rSap2t) of Candida albicans as a mucosal anticandidal vaccine

Author keywords

Candida albicans; Mucosal anticandidal vaccine; Sap2

Indexed keywords

ASPARTIC PROTEINASE; ESTRADIOL; IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; NICKEL COMPLEX; RECOMBINANT PROTEIN; SECRETED ASPARTYL PROTEINASE 2; UNCLASSIFIED DRUG;

EID: 79958817918     PISSN: 09288244     EISSN: 1574695X     Source Type: Journal    
DOI: 10.1111/j.1574-695X.2011.00802.x     Document Type: Article
Times cited : (71)

References (42)
  • 1
    • 0031228204 scopus 로고    scopus 로고
    • Changes in cytokine secretion induced by altered peptide ligands of myelin basic protein peptide 85-99
    • Ausubel LJ, Krieger JI & Hafler DA (1997) Changes in cytokine secretion induced by altered peptide ligands of myelin basic protein peptide 85-99. J Immunol 159: 2502-2512.
    • (1997) J Immunol , vol.159 , pp. 2502-2512
    • Ausubel, L.J.1    Krieger, J.I.2    Hafler, D.A.3
  • 2
    • 0035993392 scopus 로고    scopus 로고
    • The secreted aspartic proteinases as a new target in the therapy of candidiasis
    • Bein M, Schaller M & Korting HC (2002) The secreted aspartic proteinases as a new target in the therapy of candidiasis. Curr Drug Targets 3: 351-357.
    • (2002) Curr Drug Targets , vol.3 , pp. 351-357
    • Bein, M.1    Schaller, M.2    Korting, H.C.3
  • 5
    • 38349120520 scopus 로고    scopus 로고
    • Fungal vaccine: real progress from real challenges
    • Cassone A (2008) Fungal vaccine: real progress from real challenges. Lancet Infect Dis 8: 114-124.
    • (2008) Lancet Infect Dis , vol.8 , pp. 114-124
    • Cassone, A.1
  • 6
    • 0029060899 scopus 로고
    • Rat clearing a vaginal infection by Candida albicans acquired specific antibody-mediated resistance to vaginal reinfection
    • Cassone A, Boccanera M, Adriani D, Santoni G & De Bernardis F (1995) Rat clearing a vaginal infection by Candida albicans acquired specific antibody-mediated resistance to vaginal reinfection. Infect Immun 63: 2619-2625.
    • (1995) Infect Immun , vol.63 , pp. 2619-2625
    • Cassone, A.1    Boccanera, M.2    Adriani, D.3    Santoni, G.4    De Bernardis, F.5
  • 7
    • 20544441226 scopus 로고    scopus 로고
    • An outline of the role of anti-Candida antibodies within the context of passive immunization and protection from candidiasis
    • Cassone A, De Bernardis F & Torosantucci A (2005) An outline of the role of anti-Candida antibodies within the context of passive immunization and protection from candidiasis. Curr Mol Med 5: 377-382.
    • (2005) Curr Mol Med , vol.5 , pp. 377-382
    • Cassone, A.1    De Bernardis, F.2    Torosantucci, A.3
  • 8
    • 34848868749 scopus 로고    scopus 로고
    • Anticandidal immunity and vaginitis: novel chances for immune intervention
    • Cassone A, De Bernardis F & Santoni G (2007) Anticandidal immunity and vaginitis: novel chances for immune intervention. Infect Immun 75: 4675-4686.
    • (2007) Infect Immun , vol.75 , pp. 4675-4686
    • Cassone, A.1    De Bernardis, F.2    Santoni, G.3
  • 9
    • 20544435434 scopus 로고    scopus 로고
    • Defining criteria for anti-mannan antibodies to protect against candidiasis
    • Cutler JE (2005) Defining criteria for anti-mannan antibodies to protect against candidiasis. Curr Mol Med 5: 383-392.
    • (2005) Curr Mol Med , vol.5 , pp. 383-392
    • Cutler, J.E.1
  • 10
    • 33845670895 scopus 로고    scopus 로고
    • Advances in combating fungal diseases: vaccines on the threshold
    • Cutler JE, Deepe GS & Klein BS (2007) Advances in combating fungal diseases: vaccines on the threshold. Nat Rev Microbiol 5: 13-28.
    • (2007) Nat Rev Microbiol , vol.5 , pp. 13-28
    • Cutler, J.E.1    Deepe, G.S.2    Klein, B.S.3
  • 11
    • 33747761622 scopus 로고    scopus 로고
    • Prospects for development of vaccines against fungal diseases
    • Dan MJ & Levitz SM (2006) Prospects for development of vaccines against fungal diseases. Drug Resist Update 9: 105-110.
    • (2006) Drug Resist Update , vol.9 , pp. 105-110
    • Dan, M.J.1    Levitz, S.M.2
  • 12
    • 0006332402 scopus 로고    scopus 로고
    • Mucosal infection and immunity in candidiasis
    • Calderone R & Chilar R, eds) - Marcell Dekker Inc, New York, NY.
    • De Bernardis F & Boccanera M (2002) Mucosal infection and immunity in candidiasis. Fungal Pathogenesis: Principles and Clinical Applications (Calderone R & Chilar R, eds), pp. 461-482. Marcell Dekker Inc, New York, NY.
    • (2002) Fungal Pathogenesis: Principles and Clinical Applications , pp. 461-482
    • De Bernardis, F.1    Boccanera, M.2
  • 13
    • 79958841204 scopus 로고    scopus 로고
    • Protective role of antimannan and anti-aspartyl proteinase antibodies in an experimental model of Candida albicans vaginitis in rats
    • De Bernardis F, Boccanera M, Adriani D, Spreghini E, Santoni G & Cassone A (1997) Protective role of antimannan and anti-aspartyl proteinase antibodies in an experimental model of Candida albicans vaginitis in rats. Infect Immun 68: 3297-3304.
    • (1997) Infect Immun , vol.68 , pp. 3297-3304
    • De Bernardis, F.1    Boccanera, M.2    Adriani, D.3    Spreghini, E.4    Santoni, G.5    Cassone, A.6
  • 14
    • 0002475542 scopus 로고    scopus 로고
    • Rat model of Candida vaginal infection
    • (Otozak & Sande Merle A, eds) - Academic Press, New York, NY.
    • De Bernardis F, Lorenzini R & Cassone A (1999) Rat model of Candida vaginal infection. Handbook of Animal Models of Infection (Otozak & Sande Merle A, eds), pp. 735-740. Academic Press, New York, NY.
    • (1999) Handbook of Animal Models of Infection , pp. 735-740
    • De Bernardis, F.1    Lorenzini, R.2    Cassone, A.3
  • 15
    • 0034039117 scopus 로고    scopus 로고
    • Local anticandidal immune responses in a rat model of vaginal infection by and protection against Candida albicans
    • De Bernardis F, Santoni G, Boccanera M, Spreghini E, Adriani D, Morelli L & Cassone A (2000) Local anticandidal immune responses in a rat model of vaginal infection by and protection against Candida albicans. Infect Immun 68: 3297-3304.
    • (2000) Infect Immun , vol.68 , pp. 3297-3304
    • De Bernardis, F.1    Santoni, G.2    Boccanera, M.3    Spreghini, E.4    Adriani, D.5    Morelli, L.6    Cassone, A.7
  • 16
    • 0034872193 scopus 로고    scopus 로고
    • Aspartyl proteinases of Candida albicans and their role in pathogenicity
    • De Bernardis F, Sullivan PA & Cassone A (2001) Aspartyl proteinases of Candida albicans and their role in pathogenicity. Med Mycol 39: 303-313.
    • (2001) Med Mycol , vol.39 , pp. 303-313
    • De Bernardis, F.1    Sullivan, P.A.2    Cassone, A.3
  • 17
    • 0036121448 scopus 로고    scopus 로고
    • Intravaginal and intranasal immunizations are equally effective in inducing vaginal antibodies and conferring protection against vaginal candidiasis
    • De Bernardis F, Boccanera M, Adriani D, Girolamo A & Cassone A (2002) Intravaginal and intranasal immunizations are equally effective in inducing vaginal antibodies and conferring protection against vaginal candidiasis. Infect Immun 70: 2725-2729.
    • (2002) Infect Immun , vol.70 , pp. 2725-2729
    • De Bernardis, F.1    Boccanera, M.2    Adriani, D.3    Girolamo, A.4    Cassone, A.5
  • 18
    • 33845641402 scopus 로고    scopus 로고
    • Human domain antibodies against virulence traits of Candida albicans inhibit fungus adherence to vaginal epithelium and protect against experimental vaginal candidiasis
    • De Bernardis F, Liu H, O'Mahony R et al. (2007) Human domain antibodies against virulence traits of Candida albicans inhibit fungus adherence to vaginal epithelium and protect against experimental vaginal candidiasis. J Infect Dis 195: 149-157.
    • (2007) J Infect Dis , vol.195 , pp. 149-157
    • De Bernardis, F.1    Liu, H.2    O'Mahony, R.3
  • 20
    • 0024576462 scopus 로고
    • Cholera toxin and its subunits as potential as potential oral adjuvants
    • Elson CO (1989) Cholera toxin and its subunits as potential as potential oral adjuvants. Immunol Today 146: 29-33.
    • (1989) Immunol Today , vol.146 , pp. 29-33
    • Elson, C.O.1
  • 21
    • 0001789953 scopus 로고    scopus 로고
    • Cholera toxin as mucosal adjuvant
    • Kiyono H, Ogra PL & McGhee JR, eds) - Academic Press Inc, San Diego, CA.
    • Elson CO (1996) Cholera toxin as mucosal adjuvant. Mucosal Vaccines (Kiyono H, Ogra PL & McGhee JR, eds), pp. 59-72. Academic Press Inc, San Diego, CA.
    • (1996) Mucosal Vaccines , pp. 59-72
    • Elson, C.O.1
  • 22
    • 0023781763 scopus 로고
    • Genetic approach to facilitate purification of recombinant proteins with a novel metal-chelate absorbant
    • Hochuli E, Banwarth W, Dobli H, Gentz R & Stuber D (1988) Genetic approach to facilitate purification of recombinant proteins with a novel metal-chelate absorbant. Bio/Technology 6: 1321-1325.
    • (1988) Bio/Technology , vol.6 , pp. 1321-1325
    • Hochuli, E.1    Banwarth, W.2    Dobli, H.3    Gentz, R.4    Stuber, D.5
  • 23
    • 0037377310 scopus 로고    scopus 로고
    • Design and scale-up of downstream processing of monoclonal antibodies for cancer therapy: from research to clinical proof of principle
    • Horenstein AL, Crivellin F, Funaro A, Said M & Malavasi F (2003) Design and scale-up of downstream processing of monoclonal antibodies for cancer therapy: from research to clinical proof of principle. J Immunol Methods 275: 99-112.
    • (2003) J Immunol Methods , vol.275 , pp. 99-112
    • Horenstein, A.L.1    Crivellin, F.2    Funaro, A.3    Said, M.4    Malavasi, F.5
  • 24
    • 0034444895 scopus 로고    scopus 로고
    • Generation of recombinant 65-kDa mannoprotein (MP65), a major antigen target of cell-mediated immune response to Candida albicans
    • La Valle R, Sandini S, Gomez MJ, Mondello F, Romagnoli G, Nisini R & Cassone A (2000) Generation of recombinant 65-kDa mannoprotein (MP65), a major antigen target of cell-mediated immune response to Candida albicans. Infect Immun 68: 6777-6784.
    • (2000) Infect Immun , vol.68 , pp. 6777-6784
    • La Valle, R.1    Sandini, S.2    Gomez, M.J.3    Mondello, F.4    Romagnoli, G.5    Nisini, R.6    Cassone, A.7
  • 26
    • 0032457450 scopus 로고    scopus 로고
    • Declining rates of oropharyngeal candidiasis and carriage of Candida albicans associated with trends toward reduced rates of carriage of fluconazole-resistant C. albicans in human immunodeficiency virus-infected patients
    • Martins MD, Lozano-Chiu M & Rex JH (1998) Declining rates of oropharyngeal candidiasis and carriage of Candida albicans associated with trends toward reduced rates of carriage of fluconazole-resistant C. albicans in human immunodeficiency virus-infected patients. Clin Infect Dis 27: 1291-1294.
    • (1998) Clin Infect Dis , vol.27 , pp. 1291-1294
    • Martins, M.D.1    Lozano-Chiu, M.2    Rex, J.H.3
  • 28
    • 0141789642 scopus 로고    scopus 로고
    • Candida albicans secreted aspartyl proteinases in virulence and pathogenesis
    • Naglik JR, Challacombe SJ & Hube B (2003) Candida albicans secreted aspartyl proteinases in virulence and pathogenesis. Microbiol Mol Biol R 67: 400-428.
    • (2003) Microbiol Mol Biol R , vol.67 , pp. 400-428
    • Naglik, J.R.1    Challacombe, S.J.2    Hube, B.3
  • 29
    • 57349145280 scopus 로고    scopus 로고
    • Quantitative expression of the Candida albicans secreted aspartyl proteinase gene family in human oral and vaginal candidiasis
    • Naglik JR, Moyes D, Makwana J et al. (2008) Quantitative expression of the Candida albicans secreted aspartyl proteinase gene family in human oral and vaginal candidiasis. Microbiology 154: 3266-3280.
    • (2008) Microbiology , vol.154 , pp. 3266-3280
    • Naglik, J.R.1    Moyes, D.2    Makwana, J.3
  • 30
    • 0035001262 scopus 로고    scopus 로고
    • Antigenic properties and processing requirements of 65-kilodalton mannoprotein, a major antigen target of anti-Candida human T-cell response, as disclosed by specific human T-cell clones
    • Nisini R, Romagnoli G, Gomez MJ, La Valle R, Mariotti S, Teloni R & Cassone A (2001) Antigenic properties and processing requirements of 65-kilodalton mannoprotein, a major antigen target of anti-Candida human T-cell response, as disclosed by specific human T-cell clones. Infect Immun 69: 3728-3736.
    • (2001) Infect Immun , vol.69 , pp. 3728-3736
    • Nisini, R.1    Romagnoli, G.2    Gomez, M.J.3    La Valle, R.4    Mariotti, S.5    Teloni, R.6    Cassone, A.7
  • 31
    • 23244447394 scopus 로고    scopus 로고
    • Emerging fungal diseases
    • Nucci M & Marr KA (2005) Emerging fungal diseases. Clin Infect Dis 41: 521-526.
    • (2005) Clin Infect Dis , vol.41 , pp. 521-526
    • Nucci, M.1    Marr, K.A.2
  • 33
    • 33846466508 scopus 로고    scopus 로고
    • Epidemiology of invasive candidiasis: a persistent public health problem
    • Pfaller MA & Diekema DJ (2007) Epidemiology of invasive candidiasis: a persistent public health problem. Clin Microbiol Rev 20: 133-163.
    • (2007) Clin Microbiol Rev , vol.20 , pp. 133-163
    • Pfaller, M.A.1    Diekema, D.J.2
  • 34
    • 0033230445 scopus 로고    scopus 로고
    • Diagnosis and treatment of oropharyngeal candidiasis in patients infected with HIV: a critical reassessment
    • Powderly WG, Mayer KH & Perfect JR (1999) Diagnosis and treatment of oropharyngeal candidiasis in patients infected with HIV: a critical reassessment. AIDS Res Hum Retrov 15: 1405-1412.
    • (1999) AIDS Res Hum Retrov , vol.15 , pp. 1405-1412
    • Powderly, W.G.1    Mayer, K.H.2    Perfect, J.R.3
  • 35
    • 0025240749 scopus 로고
    • The secreted aspartate proteinase of Candida albicans: physiology of secretion and virulence of a proteinase-deficient mutant
    • Ross IK, De Bernardis F, Emerson GW, Cassone A & Sullivan PA (1990) The secreted aspartate proteinase of Candida albicans: physiology of secretion and virulence of a proteinase-deficient mutant. J Gen Microbiol 136: 687-694.
    • (1990) J Gen Microbiol , vol.136 , pp. 687-694
    • Ross, I.K.1    De Bernardis, F.2    Emerson, G.W.3    Cassone, A.4    Sullivan, P.A.5
  • 36
    • 0347758959 scopus 로고    scopus 로고
    • Generation of a highly immunogenic recombinant enolase of the human opportunistic pathogen Candida albicans
    • Sandini S, Melchionna R, Arancia S, Gomez MJ & La Valle R (1999) Generation of a highly immunogenic recombinant enolase of the human opportunistic pathogen Candida albicans. Biotechnol Appl Bioc 29: 223-227.
    • (1999) Biotechnol Appl Bioc , vol.29 , pp. 223-227
    • Sandini, S.1    Melchionna, R.2    Arancia, S.3    Gomez, M.J.4    La Valle, R.5
  • 37
    • 34047250154 scopus 로고    scopus 로고
    • The 65-kilodalton mannoprotein gene of Candida albicans encodes a putative β-glucanase adhesin required for hyphal morphogenesis and experimental pathogenicity
    • Sandini S, La Valle R, De Bernardis F, Macrì C & Cassone A (2007) The 65-kilodalton mannoprotein gene of Candida albicans encodes a putative β-glucanase adhesin required for hyphal morphogenesis and experimental pathogenicity. Cell Microbiol 9: 1223-1238.
    • (2007) Cell Microbiol , vol.9 , pp. 1223-1238
    • Sandini, S.1    La Valle, R.2    De Bernardis, F.3    Macrì, C.4    Cassone, A.5
  • 38
    • 0036719923 scopus 로고    scopus 로고
    • Immune-mediated protection against vaginal candidiasis: evidence for a major role of vaginal CD4+T cells and possible participation of other local lymphocyte effectors
    • Santoni G, Boccanera M, Adriani D, Lucciarini R, Amantini C, Cassone A & De Bernardis F (2002) Immune-mediated protection against vaginal candidiasis: evidence for a major role of vaginal CD4+T cells and possible participation of other local lymphocyte effectors. Infect Immun 70: 4791-4797.
    • (2002) Infect Immun , vol.70 , pp. 4791-4797
    • Santoni, G.1    Boccanera, M.2    Adriani, D.3    Lucciarini, R.4    Amantini, C.5    Cassone, A.6    De Bernardis, F.7
  • 39
    • 0030924566 scopus 로고    scopus 로고
    • Ultrastructural localization of the secretory aspartyl proteinase in Candida albicans cell wall in vitro and in experimentally infected rat vagina
    • Stringaro A, Crateri P, Pellegrini G, Arancia G, Cassone A & De Bernardis F (1997) Ultrastructural localization of the secretory aspartyl proteinase in Candida albicans cell wall in vitro and in experimentally infected rat vagina. Mycopathologia 137: 95-107.
    • (1997) Mycopathologia , vol.137 , pp. 95-107
    • Stringaro, A.1    Crateri, P.2    Pellegrini, G.3    Arancia, G.4    Cassone, A.5    De Bernardis, F.6
  • 40
    • 0000926770 scopus 로고
    • System for high-level production in E. coli and rapid purification of recombinant proteins
    • application to epitope mapping preparation of antibodies and structure/function analysis. (Lefkovitz I & Pernis B, eds) - Academic Press Inc, Orlando, FL.
    • Stuber D, Matile H & Garotta G (1990) System for high-level production in E. coli and rapid purification of recombinant proteins:application to epitope mapping preparation of antibodies and structure/function analysis. Immunological Methods (Lefkovitz I & Pernis B, eds), pp. 122-151. Academic Press Inc, Orlando, FL.
    • (1990) Immunological Methods , pp. 122-151
    • Stuber, D.1    Matile, H.2    Garotta, G.3
  • 41
    • 77949805994 scopus 로고    scopus 로고
    • Identification of inhibitors of pharmacoresistant Candida albicans strains from a library of bicyclic peptidomimetic compounds
    • Trabocchi A, Mannino C, Machetti F, De Bernardis S, Cauda R, Cassone A & Guarna A (2010) Identification of inhibitors of pharmacoresistant Candida albicans strains from a library of bicyclic peptidomimetic compounds. J Med Chem 53: 2502-2509.
    • (2010) J Med Chem , vol.53 , pp. 2502-2509
    • Trabocchi, A.1    Mannino, C.2    Machetti, F.3    De Bernardis, S.4    Cauda, R.5    Cassone, A.6    Guarna, A.7


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