Evaluation of ordered mesoporous silica as a carrier for poorly soluble drugs: Influence of pressure on the structure and drug release

Journal of Pharmaceutical Sciences

Volumn 100, Issue 8, 2011, Pages 3411-3420

  Vialpando, Monica ^a   Aerts, Alexander ^b   Persoons, Jeroen ^c   Martens, Johan ^b   Van Den Mooter, Guy ^a  

^a DEPARTMENT OF PHARMACEUTICAL AND PHARMACOLOGICAL SCIENCES   (Belgium)

^b UNIVERSITY OF LEUVEN   (Belgium)

^c Formac Pharmaceuticals NV   (Belgium)

Author keywords

Amorphous; COK 12; Compression; Dissolution; Itraconazole; Mesoporous silica; Physical characterization; SBA 15; Solid dosage form

Indexed keywords

COK 12; CROSCARMELLOSE SODIUM; ITRACONAZOLE; MICROCRYSTALLINE CELLULOSE; SBA 15; SILICON DIOXIDE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED RELEASE FORMULATION; DIFFERENTIAL SCANNING CALORIMETRY; DRUG RELEASE; DRUG SOLUBILITY; DRUG STRUCTURE; SCANNING ELECTRON MICROSCOPY; SMALL ANGLE SCATTERING; TRANSMISSION ELECTRON MICROSCOPY;

EID: 79958812827     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.22535     Document Type: Article

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