Rab GTPases and tethering in the yeast endocytic pathway

Small GTPases

Volumn 2, Issue 3, 2011, Pages 182-186

  Lachmann, Jens ^a   Ungermann, Christian ^a   Engelbrecht Vandré, Siegfried ^a  

^a UNIVERSITY OF OSNABRÜCK   (Germany)

Author keywords

CORVET; HOPS; Membrane fusion; Mon1 Ccz1; Rab GTPases; SNAREs; Tethers; Vps21; Ypt7

Indexed keywords

PROTEINYPT7; RAB PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL VACUOLE; COMPLEX FORMATION; ENDOCYTOSIS; ENDOSOME; ENZYME ACTIVITY; EUKARYOTE; NONHUMAN; PROTEIN INTERACTION; REGULATORY MECHANISM; SACCHAROMYCES CEREVISIAE; YEAST CELL;

EUKARYOTA;

EID: 79958799708     PISSN: 21541248     EISSN: 21541256     Source Type: Journal    
DOI: 10.4161/sgtp.2.3.16701     Document Type: Article

References (42)

1. Bröcker C, Engelbrecht-Vandré S, Ungermann C. Multisubunit tethering complexes and their role in membrane fusion. Curr Biol 2010; 20:R943-52; PMID: 21056839; DOI:10.1016/j.cub.2010.09.015.
2. Cai H, Reinisch K, Ferro-Novick S. Coats, Tethers, Rabs, and SNAREs Work Together to Mediate the Intracellular Destination of a Transport Vesicle. Dev Cell 2007; 12:671-82; PMID: 17488620; DOI:10.1016/j.devcel.2007.04.005.
3. Hickey CM, Wickner W. HOPS initiates vacuole docking by tethering membranes before trans-SNARE complex assembly. Mol Biol Cell 2010; 21:2297-305; PMID: 20462954; DOI:10.1091/mbc. E10-01-0044.
4. Wickner W. Membrane Fusion: Five Lipids, Four SNAREs, Three Chaperones, Two Nucleotides, and a Rab, All Dancing in a Ring on Yeast Vacuoles. Annu Rev Cell Dev Biol 2010; 26:115-36; PMID: 20521906; DOI:10.1146/annurev-cellbio-100109-104131.
5. Hutagalung AH, Novick PJ. Role of Rab GTPases in membrane traffic and cell physiology. Physiol Rev 2011; 91:119-49; PMID: 21248164; DOI:10.1152/physrev.00059.2009.
6. Barr F, Lambright DG. Rab GEFs and GAPs. Curr Opin Cell Biol 2010; 22:461-70; PMID: 20466531; DOI:10.1016/j.ceb.2010.04.007.
7. Stenmark H. Rab GTPases as coordinators of vesicle traffic. Nat Rev Mol Cell Biol 2009; 10:513-25; PMID: 19603039; DOI:10.1038/nrm2728.
8. Pereira-Leal JB, Hume AN, Seabra MC. Prenylation of Rab GTPases: molecular mechanisms and involvement in genetic disease. FEBS Lett 2001; 498:197-200; PMID: 11412856; DOI:10.1016/S0014-5793(01)02483-8.
9. Pfeffer S, Aivazian D. Targeting Rab GTPases to distinct membrane compartments. Nat Rev Mol Cell Biol 2004; 5:886-96; PMID: 15520808; DOI:10.1038/nrm1500.
10. Pfeffer SR. Structural clues to Rab GTPase functional diversity. J Biol Chem 2005; 280:15485-8; PMID: 15746102; DOI:10.1074/jbc.R500003200.
11. Novick P, Medkova M, Dong G, Hutagalung A, Reinisch K, Grosshans B. Interactions between Rabs, tethers, SNAREs and their regulators in exocytosis. Biochem Soc Trans 2006; 34:683-6; PMID: 17052174; DOI:10.1042/BST0340683.
12. Rivera-Molina FE, Novick PJ. A Rab GAP cascade defines the boundary between two Rab GTPases on the secretory pathway. Proc Natl Acad Sci USA 2009; 106:14408-13; PMID: 19666511; DOI:10.1073/pnas.0906536106.
13. Del Conte-Zerial P, Brusch L, Rink JC, Collinet C, Kalaidzidis Y, Zerial M, et al. Membrane identity and GTPase cascades regulated by toggle and cutout switches. Mol Syst Biol 2008; 4:206; PMID: 18628746; DOI:10.1038/msb.2008.45.
14. Rink J, Ghigo E, Kalaidzidis Y, Zerial M. Rab conversion as a mechanism of progression from early to late endosomes. Cell 2005; 122:735-49; PMID: 16143105; DOI:10.1016/j.cell.2005.06.043.
15. Krieger E, Koraimann G, Vriend G. Increasing the precision of comparative models with YASARA NOVA-a self-parameterizing force field. Proteins 2002; 47:393-402; PMID: 11948792; DOI:10.1002/prot.10104.
16. Notredame C. T-coffee: a novel method for fast and accurate multiple sequence alignment. J Mol Biol 2000; 302:205-17; PMID: 10964570; DOI:10.1006/jmbi.2000.4042.
17. Carney DS, Davies BA, Horazdovsky BF. Vps9 domain-containing proteins: activators of Rab5 GTPases from yeast to neurons. Trends Cell Biol 2006; 16:27-35; PMID: 16330212; DOI:10.1016/j. tcb.2005.11.001.
18. Horiuchi H, Lippé R, McBride HM, Rubino M, Woodman P, Stenmark H, et al. A novel Rab5 GDP/GTP exchange factor complexed to Rabaptin-5 links nucleotide exchange to effector recruitment and function. Cell 1997; 90:1149-59; PMID: 9323142; DOI:10.1016/S0092-8674(00)80380-3.
19. Nordmann M, Cabrera M, Perz A, Bröcker C, Ostrowicz C, Engelbrecht-Vandré S, et al. The Mon1-Ccz1 complex is the GEF of the late endosomal Rab7 homolog Ypt7. Curr Biol 2010; 20:1654-9; PMID: 20797862; DOI:10.1016/j.cub.2010.08.002.
20. Poteryaev D, Datta S, Ackema K, Zerial M, Spang A. Identification of the switch in early-to-late endosome transition. Cell 2010; 141:497-508; PMID: 20434987; DOI:10.1016/j.cell.2010.03.011.
21. Kinchen JM, Ravichandran KS. Identification of two evolutionarily conserved genes regulating processing of engulfed apoptotic cells. Nature 2010; 464:778-82; PMID: 20305638; DOI:10.1038/nature08853.
22. Li W, Zou W, Zhao D, Yan J, Zhu Z, Lu J, et al. C. elegans Rab GTPase activating protein TBC-2 promotes cell corpse degradation by regulating the small GTPase RAB-5. Development 2009; 136:2445-55; PMID: 19542357; DOI:10.1242/dev.035949.
23. Chotard L, Mishra AK, Sylvain M, Tuck S, Lambright DG, Rocheleau CE. TBC-2 regulates RAB-5/RAB-7-mediated endosomal trafficking in Caenorhabditis elegans. Mol Biol Cell 2010; 21:2285-96; PMID: 20462958; DOI:10.1091/mbc.E09-11-0947.
24. Haas AK, Fuchs E, Kopajtich R, Barr FA. A GTPaseactivating protein controls Rab5 function in endocytic trafficking. Nat Cell Biol 2005; 7:887-93; PMID: 16086013; DOI:10.1038/ncb1290.
25. Suh HY, Lee D, Lee K, Ku B, Choi S, Woo J, et al. Structural insights into the dual nucleotide exchange and GDI displacement activity of SidM/DrrA. EMBO J 2010; 29:496-504; PMID: 19942850; DOI:10.1038/emboj.2009.347.
26. Zhu Y, Hu L, Zhou Y, Yao Q, Liu L, Shao F. Structural mechanism of host Rab1 activation by the bifunctional Legionella type IV effector SidM/DrrA. Proc Natl Acad Sci USA 2010; 107:4699-704; PMID: 20176951; DOI:10.1073/pnas.0914231107.
27. Schoebel S, Oesterlin LK, Blankenfeldt W, Goody RS, Itzen A. RabGDI displacement by DrrA from Legionella is a consequence of its guanine nucleotide exchange activity. Mol Cell 2009; 36:1060-72; PMID: 20064470; DOI:10.1016/j.molcel. 2009.11.014.
28. Peplowska K, Markgraf DF, Ostrowicz CW, Bange G, Ungermann C. The CORVET tethering complex interacts with the yeast Rab5 homolog Vps21 and is involved in endo-lysosomal biogenesis. Dev Cell 2007; 12:739-50; PMID: 17488625; DOI:10.1016/j. devcel.2007.03.006.
29. Wurmser AE, Sato TK, Emr SD. New component of the vacuolar class C-Vps complex couples nucleotide exchange on the Ypt7 GTPase to SNARE-dependent docking and fusion. J Cell Biol 2000; 151:551-62; PMID: 11062257; DOI:10.1083/jcb.151.3.551.
30. Seals DF, Eitzen G, Margolis N, Wickner WT, Price AA. Ypt/Rab effector complex containing the Sec1 homolog Vps33p is required for homotypic vacuole fusion. Proc Natl Acad Sci USA 2000; 97:9402-7; PMID: 10944212; DOI:10.1073/pnas.97.17.9402.
31. Markgraf DF, Ahnert F, Arlt H, Mari M, Peplowska K, Epp N, et al. The CORVET subunit Vps8 cooperates with the Rab5 homolog Vps21 to induce clustering of late endosomal compartments. Mol Biol Cell 2009; 20:5276-89; PMID: 19828734; DOI:10.1091/mbc.E09-06-0521.
32. Plemel RL, Lobingier BT, Brett CL, Angers CG, Nickerson DP, Paulsel A, et al. Subunit organization and Rab interactions of Vps-C protein complexes that control endolysosomal membrane traffic. Mol Biol Cell 2011; 22:1353-63; PMID: 21325627; DOI:10.1091/mbc.E10-03-0260.
33. Brett CL, Plemel RL, Lobinger BT, Vignali M, Fields S, Merz AJ. Efficient termination of vacuolar Rab GTPase signaling requires coordinated action by a GAP and a protein kinase. J Cell Biol 2008; 182:1141-51; PMID: 18809726; DOI:10.1083/jcb.200801001.
34. Ostrowicz CW, Bröcker C, Ahnert F, Nordmann M, Lachmann J, Peplowska K, et al. Defined subunit arrangement and rab interactions are required for functionality of the HOPS tethering complex. Traffic 2010; 11:1334-46; PMID: 20604902; DOI:10.1111/j.1600-0854.2010.01097.x.
35. Raymond CK, Howald-Stevenson I, Vater CA, Stevens TH. Morphological classification of the yeast vacuolar protein sorting mutants: evidence for a prevacuolar compartment in class E vps mutants. Mol Biol Cell 1992; 3:1389-402; PMID: 1493335.
36. Nickerson DP, Brett CL, Merz AJ. Vps-C complexes: gatekeepers of endolysosomal traffic. Curr Opin Cell Biol 2009; 21:543-51; PMID: 19577915; DOI:10.1016/j.ceb.2009.05.007.
37. Südhof TC, Rothman JE. Membrane fusion: grappling with SNARE and SM proteins. Science 2009; 323:474-7; PMID: 19164740; DOI:10.1126/science. 1161748.
38. Krämer L, Ungermann C. HOPS drives vacuole fusion by binding the vacuolar SNARE complex and the Vam7 PX domain via two distinct sites. MBoC in Press 2011; DOI:10.1091/mbc.E11-02-0104.
39. Bonifacino JS, Hurley JH. Retromer. Curr Opin Cell Biol 2008; 20:427-36; PMID: 18472259; DOI:10.1016/j.ceb.2008.03.009.
40. Balderhaar HJK, Arlt H, Ostrowicz C, Bröcker C, Sündermann F, Brandt R, et al. The Rab GTPase Ypt7 is linked to retromer-mediated receptor recycling and fusion at the yeast late endosome. J Cell Sci 2010; 123:4085-94; PMID: 21062894; DOI:10.1242/jcs.071977.
41. Seaman MNJ, Harbour ME, Tattersall D, Read E, Bright N. Membrane recruitment of the cargoselective retromer subcomplex is catalysed by the small GTPase Rab7 and inhibited by the Rab-GAP TBC1D5. J Cell Sci 2009; 122:2371-82; PMID: 19531583; DOI:10.1242/jcs.048686.
42. Bonifacino JS, Rojas R. Retrograde transport from endosomes to the trans-Golgi network. Nat Rev Mol Cell Biol 2006; 7:568-79; PMID: 16936697; DOI:10.1038/nrm1985.