Targeted metabolomic analyses of cellular models of pelizaeus-merzbacher disease reveal plasmalogen and myo-inositol solute carrier dysfunction

Lipids in Health and Disease

Volumn 10, Issue , 2011, Pages

  Wood, Paul L ^a   Smith, Tara ^a   Pelzer, Lindsay ^a   Goodenowe, Dayan B ^a  

^a Phenomenome Discoveries Inc   (Canada)

Author keywords

158JP oligodendrocytes; fibroblasts; leukodystrophy; lymphocytes; myo inositol transporter; Pelizaeus Merzbacher disease; peroxisomal disorders; plasmalogens

Indexed keywords

ETHANOLAMINE; INOSITOL; PLASMALOGEN; COTRANSPORTER; HEAT SHOCK PROTEIN; PHOSPHATIDAL ETHANOLAMINES; PLP1 PROTEIN, HUMAN; PROTEOLIPID PROTEIN; SLC5A3 PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; DISORDERS OF PEROXISOMAL FUNCTIONS; FIBROBLAST; GENETIC DISORDER; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; LIPOGENESIS; LYMPHOCYTE; METABOLOMICS; MOUSE; NONHUMAN; OLIGODENDROGLIA; PELIZAEUS MERZBACHER DISEASE; PROTEIN ANALYSIS; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; RNA ISOLATION; TRANSPORT AT THE CELLULAR LEVEL; ANIMAL; CELL LINE; GENE EXPRESSION; GENETICS; METABOLISM; METABOLOME; MUTATION;

MURINAE;

ANIMALS; CELL LINE; FIBROBLASTS; GENE EXPRESSION; HEAT-SHOCK PROTEINS; HUMANS; INOSITOL; LYMPHOCYTES; METABOLOME; MICE; MUTATION; MYELIN PROTEOLIPID PROTEIN; OLIGODENDROGLIA; PELIZAEUS-MERZBACHER DISEASE; PLASMALOGENS; SYMPORTERS;

EID: 79958787913     PISSN: None     EISSN: 1476511X     Source Type: Journal    
DOI: 10.1186/1476-511X-10-102     Document Type: Article

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