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Volumn 4, Issue , 2011, Pages 57-71

Tolvaptan, hyponatremia, and heart failure

Author keywords

Arginine vasopressin antagonist; Heart failure; Hyponatremia; Tolvaptan

Indexed keywords

ARGIPRESSIN; ARGIPRESSIN DERIVATIVE; CONIVAPTAN; FUROSEMIDE; KETOCONAZOLE; PLACEBO; RIFAMPICIN; TOLVAPTAN;

EID: 79958776450     PISSN: None     EISSN: 11787058     Source Type: Journal    
DOI: 10.2147/IJNRD.S7032     Document Type: Review
Times cited : (27)

References (46)
  • 1
    • 52949105320 scopus 로고    scopus 로고
    • Mechanisms, risks, and new treatmen options for hyponatremia
    • Ghali JK. Mechanisms, risks, and new treatmen options for hyponatremia. Cardiology. 2008;111:147-157.
    • (2008) Cardiology , vol.111 , pp. 147-157
    • Ghali, J.K.1
  • 2
    • 30944460468 scopus 로고    scopus 로고
    • Mild chronic hyponatremia is associated with falls, unsteadiness and attention deficits
    • Renneboog B, Vendemergel X, Manto MN, et al. Mild chronic hyponatremia is associated with falls, unsteadiness and attention deficits. Am J Med. 2006;119:71e1-71e8.
    • (2006) Am J Med , vol.119
    • Renneboog, B.1    Vendemergel, X.2    Manto, M.N.3
  • 3
    • 67649982903 scopus 로고    scopus 로고
    • Hyponatremia associated with large bone fracture in elderly patients
    • Sandhu HS, Gilles E, DeVita MV, et al. Hyponatremia associated with large bone fracture in elderly patients. Int Urol Nephrol. 2009;41: 733-737.
    • (2009) Int Urol Nephrol , vol.41 , pp. 733-737
    • Sandhu, H.S.1    Gilles, E.2    Devita, M.V.3
  • 4
    • 77749330808 scopus 로고    scopus 로고
    • Hyponatremia independent of osteoporosis is associated with fracture occurrence
    • Kinsell S, Moran S, Sullivan MO, et al. Hyponatremia independent of osteoporosis is associated with fracture occurrence. Clin J Am Soc Nephrol. 2010;5:275-280.
    • (2010) Clin J Am Soc Nephrol , vol.5 , pp. 275-280
    • Kinsell, S.1    Moran, S.2    Sullivan, M.O.3
  • 5
    • 46249105557 scopus 로고    scopus 로고
    • Mild hyponatremia and risk of fracture in the ambulatory elderly
    • Gankam Kengne F, Andres C, Sattar L, et al. Mild hyponatremia and risk of fracture in the ambulatory elderly. QJM. 2008;101:583-588.
    • (2008) QJM , vol.101 , pp. 583-588
    • Gankam, K.F.1    Andres, C.2    Sattar, L.3
  • 6
    • 68749103375 scopus 로고    scopus 로고
    • Mortality after hospitalization with mild, moderate, and severe hyponatremia
    • Waikar SS, Mount DB, Curhan GC. Mortality after hospitalization with mild, moderate, and severe hyponatremia. Am J Med. 2009;122: 857-865.
    • (2009) Am J Med , vol.122 , pp. 857-865
    • Waikar, S.S.1    Mount, D.B.2    Curhan, G.C.3
  • 8
    • 67649781921 scopus 로고    scopus 로고
    • Mild hyponatremia carries a poor prognosis in community subjects
    • Sajadieh A, Binici Z, Mouridsen MR, et al. Mild hyponatremia carries a poor prognosis in community subjects. Am J Med. 2009;122: 679-686.
    • (2009) Am J Med , vol.122 , pp. 679-686
    • Sajadieh, A.1    Binici, Z.2    Mouridsen, M.R.3
  • 9
    • 34548348725 scopus 로고    scopus 로고
    • Relationship between admission serum sodium concentration and clinical outcomes in patients hospitalized for heart failure: An analysis from the OPTIMIZE-HF registry. Optimize-HF Investigators and Coordinators
    • Gheorghiade M, Abraham WT, Albert NM, et al. Relationship between admission serum sodium concentration and clinical outcomes in patients hospitalized for heart failure: an analysis from the OPTIMIZE-HF registry. Optimize-HF Investigators and Coordinators. Eur Heart J. 2007;28:980-988.
    • (2007) Eur Heart J , vol.28 , pp. 980-988
    • Gheorghiade, M.1    Abraham, W.T.2    Albert, N.M.3
  • 10
    • 34548303592 scopus 로고    scopus 로고
    • Hyponatremia in heart failure: A call for redefinition
    • Ghali JK. Hyponatremia in heart failure: a call for redefinition. Eur Heart J. 2007;28:920-921.
    • (2007) Eur Heart J , vol.28 , pp. 920-921
    • Ghali, J.K.1
  • 11
    • 33745726360 scopus 로고    scopus 로고
    • Is asymptomatic hyponatremia really asymptomatic?
    • Decaux G. Is asymptomatic hyponatremia really asymptomatic? Am J Med. 2006;119(7A):S79-S82.
    • (2006) Am J Med , vol.119 , Issue.7 A
    • Decaux, G.1
  • 12
    • 34247205056 scopus 로고    scopus 로고
    • The body fluids and kidneys
    • In: Guyton AC, Hall JE, editors, Philadelphia (PA): WB Saunders Company
    • Guyton AC. The body fluids and kidneys. In: Guyton AC, Hall JE, editors. Textbook of Medical Physiology. Philadelphia (PA): WB Saunders Company; 2006:291-414.
    • (2006) Textbook of Medical Physiology , pp. 291-414
    • Guyton, A.C.1
  • 13
    • 0027163672 scopus 로고
    • Mechanosensitive channels transducer osmosensitivity in supraoptic neurons
    • Oliet SH, Bourque CW. Mechanosensitive channels transducer osmosensitivity in supraoptic neurons. Nature. 1993;364:341-343.
    • (1993) Nature , vol.364 , pp. 341-343
    • Oliet, S.H.1    Bourque, C.W.2
  • 14
    • 0021023124 scopus 로고
    • Role of volume and osmolality in the control of plasma vasopressin in dehydrated dogs
    • Wade CE, Keil LC, Ramsay DJ. Role of volume and osmolality in the control of plasma vasopressin in dehydrated dogs. Neuroendocrinology. 1983;37:349-353.
    • (1983) Neuroendocrinology , vol.37 , pp. 349-353
    • Wade, C.E.1    Keil, L.C.2    Ramsay, D.J.3
  • 15
    • 33745712365 scopus 로고    scopus 로고
    • Water and sodium retention in edematous disorder: Role of vasopressin and aldosterone
    • Schrier RW. Water and sodium retention in edematous disorder: role of vasopressin and aldosterone. Am J Med. 2006;119:S47-S53.
    • (2006) Am J Med , vol.119
    • Schrier, R.W.1
  • 16
    • 0018460643 scopus 로고
    • Osmotic and nonosmotic control of vasopressin release
    • Schrier RW, Berl T, Anderson RJ. Osmotic and nonosmotic control of vasopressin release. Am J Physiol. 1979;236:F321-F332.
    • (1979) Am J Physiol , vol.236
    • Schrier, R.W.1    Berl, T.2    Anderson, R.J.3
  • 17
    • 0020319081 scopus 로고
    • Two possible actions for circulating angiotensin II in the control of vasopressin release
    • Mitchell LD, Barron K, Brody MJ, et al. Two possible actions for circulating angiotensin II in the control of vasopressin release. Peptides. 1982;3:503-507.
    • (1982) Peptides , vol.3 , pp. 503-507
    • Mitchell, L.D.1    Barron, K.2    Brody, M.J.3
  • 18
    • 0031650278 scopus 로고    scopus 로고
    • Molecular pharmacology of human vasopressin receptors
    • Thibonnier M, Conarty DM, Preston JA, et al. Molecular pharmacology of human vasopressin receptors. Adv Exp Med Biol. 1998;449:251-276.
    • (1998) Adv Exp Med Biol , vol.449 , pp. 251-276
    • Thibonnier, M.1    Conarty, D.M.2    Preston, J.A.3
  • 19
    • 34247259624 scopus 로고    scopus 로고
    • Therapeutic potential of vasopressin receptor antagonists
    • Ali F, Guglin M, Vaitkevicius P, et al. Therapeutic potential of vasopressin receptor antagonists. Drugs. 2007;67:847-858.
    • (2007) Drugs , vol.67 , pp. 847-858
    • Ali, F.1    Guglin, M.2    Vaitkevicius, P.3
  • 20
    • 0033053453 scopus 로고    scopus 로고
    • Physiology and pathophysiology of renal quaporins
    • Nielsen S, Kwon TH, Christensen BM, et al. Physiology and pathophysiology of renal quaporins. J Am Soc Nephrol. 1999;10:647-663.
    • (1999) J Am Soc Nephrol , vol.10 , pp. 647-663
    • Nielsen, S.1    Kwon, T.H.2    Christensen, B.M.3
  • 21
    • 1342289554 scopus 로고    scopus 로고
    • The vasopressin V1B receptor critically regulates hypothalamic-pituitary-adrenal axis activity under both stress and resting conditions
    • Tanoue A, Ito S, Honda K, et al. The vasopressin V1B receptor critically regulates hypothalamic-pituitary-adrenal axis activity under both stress and resting conditions. J Clin Invest. 2004;113:302-309.
    • (2004) J Clin Invest , vol.113 , pp. 302-309
    • Tanoue, A.1    Ito, S.2    Honda, K.3
  • 22
    • 79958811811 scopus 로고    scopus 로고
    • Samsca (tolvaptan) [prescribing Information]. Tokyo, Japan: Otsuka Pharmaceutical Co, Ltd, Accessed May 2, 2010
    • Samsca (tolvaptan) [prescribing Information]. Tokyo, Japan: Otsuka Pharmaceutical Co, Ltd. 2009. http://www.samsca.com/pdf/samscaPI.pdf. Accessed May 2, 2010.
    • (2009)
  • 23
    • 0032240078 scopus 로고    scopus 로고
    • OPC-41061, a highly potent human vasopressin V2-receptor antagonist: Pharmacological profile and aquaretic effect by single and multiple oral dosing in rats
    • Yamamura Y, Nakamura S, Itoh S, et al. OPC-41061, a highly potent human vasopressin V2-receptor antagonist: Pharmacological profile and aquaretic effect by single and multiple oral dosing in rats. J Pharmacol Exp Ther. 1998;287:860-867.
    • (1998) J Pharmacol Exp Ther , vol.287 , pp. 860-867
    • Yamamura, Y.1    Nakamura, S.2    Itoh, S.3
  • 24
    • 36148983374 scopus 로고    scopus 로고
    • Pharmacokinetics, pharmacodynamics, and safety of tolvaptan, a nonpeptide AVP antagonist, during ascending single-dose studies in healthy subjects
    • Shoaf SE, Wang Z, Bricmont P, et al. Pharmacokinetics, pharmacodynamics, and safety of tolvaptan, a nonpeptide AVP antagonist, during ascending single-dose studies in healthy subjects. J Clin Pharmacol. 2007;47:1498-1507.
    • (2007) J Clin Pharmacol , vol.47 , pp. 1498-1507
    • Shoaf, S.E.1    Wang, Z.2    Bricmont, P.3
  • 25
    • 27344438770 scopus 로고    scopus 로고
    • Comparison of two doses and dosing regimens of tolvaptan in congestive heart failure
    • Hauptman PJ, Zimmer C, Udelson J, et al. Comparison of two doses and dosing regimens of tolvaptan in congestive heart failure. J Cardiovasc Pharmacol. 2005;46:609-614.
    • (2005) J Cardiovasc Pharmacol , vol.46 , pp. 609-614
    • Hauptman, P.J.1    Zimmer, C.2    Udelson, J.3
  • 26
    • 0033965154 scopus 로고    scopus 로고
    • Effects of the V2 receptor antagonist OPC-41061 and the loop diuretic furosemide alone and in combination in rats
    • Hirano T, Yamamura Y, Nakamura S, et al. Effects of the V2 receptor antagonist OPC-41061 and the loop diuretic furosemide alone and in combination in rats. J Pharmacol Exp Ther. 2000;292:288-294.
    • (2000) J Pharmacol Exp Ther , vol.292 , pp. 288-294
    • Hirano, T.1    Yamamura, Y.2    Nakamura, S.3
  • 27
    • 75449112325 scopus 로고    scopus 로고
    • Effect of ketoconazole and grapefruit juice, CYP3A4 inhibitors, on the pharmacokinetics of tolvaptan, a non-peptide vasopressin antagonist
    • Shoaf SE, Mallikaarjun S. Effect of ketoconazole and grapefruit juice, CYP3A4 inhibitors, on the pharmacokinetics of tolvaptan, a non-peptide vasopressin antagonist. Clin Pharmacol Ther. 2008;83:S57.
    • (2008) Clin Pharmacol Ther , vol.83
    • Shoaf, S.E.1    Mallikaarjun, S.2
  • 28
    • 75449112325 scopus 로고    scopus 로고
    • Effect of rifampin, CYP3A4 inducer, on the pharmacokinetics and pharmacodynamics of tolvaptan, a non-peptide vasopressin antagonist
    • Mallikaarjun S. Effect of rifampin, CYP3A4 inducer, on the pharmacokinetics and pharmacodynamics of tolvaptan, a non-peptide vasopressin antagonist. Clin Pharmacol Ther. 2008;83:S57.
    • (2008) Clin Pharmacol Ther , vol.83
    • Mallikaarjun, S.1
  • 29
    • 25444438742 scopus 로고    scopus 로고
    • Tolvaptan administration does not affect steady state amiodarone concentrations in patients with cardiac arrhythmias
    • Shoaf SE, Elizari MV, Wang Z, et al. Tolvaptan administration does not affect steady state amiodarone concentrations in patients with cardiac arrhythmias. J Cardiovasc Pharmacol Ther. 2005;10:165-171.
    • (2005) J Cardiovasc Pharmacol Ther , vol.10 , pp. 165-171
    • Shoaf, S.E.1    Elizari, M.V.2    Wang, Z.3
  • 30
    • 34547951340 scopus 로고    scopus 로고
    • Pharmacokinetic and pharmacodynamic interaction between tolvaptan, a non-peptide AVP antagonist, and furosemide or hydrochlorothiazide
    • Shoaf SE, Bramer SL, Bricmont P, et al. Pharmacokinetic and pharmacodynamic interaction between tolvaptan, a non-peptide AVP antagonist, and furosemide or hydrochlorothiazide. J Cardiovasc Pharmacol. 2007;50:213-222.
    • (2007) J Cardiovasc Pharmacol , vol.50 , pp. 213-222
    • Shoaf, S.E.1    Bramer, S.L.2    Bricmont, P.3
  • 31
    • 4043163667 scopus 로고    scopus 로고
    • Lack of clinically significant interaction between steady state tolvaptan and digoxin in healthy volunteers
    • Shoaf SE, Wang Z, Mallikaarjun S, et al. Lack of clinically significant interaction between steady state tolvaptan and digoxin in healthy volunteers. Clin Pharmacol Ther. 2004;75:P37.
    • (2004) Clin Pharmacol Ther , vol.75
    • Shoaf, S.E.1    Wang, Z.2    Mallikaarjun, S.3
  • 32
    • 33947713810 scopus 로고    scopus 로고
    • Effects of oral tolvaptan in patients hospitalized for worsening heart failure, the EVEREST outcome trial
    • Konstam MA, Gheorghiade M, Burnett JC, et al. Effects of oral tolvaptan in patients hospitalized for worsening heart failure, the EVEREST outcome trial. JAMA. 2007;297:1319-1331.
    • (2007) JAMA , vol.297 , pp. 1319-1331
    • Konstam, M.A.1    Gheorghiade, M.2    Burnett, J.C.3
  • 33
    • 77956923207 scopus 로고    scopus 로고
    • A multicenter, open-label, doseranging study to exploratively evaluate the efficacy, safety, and dose-response of tolvaptan in patients with decompensated liver cirrhosis
    • Okita K, Sakaida I, Okada M, et al. A multicenter, open-label, doseranging study to exploratively evaluate the efficacy, safety, and dose-response of tolvaptan in patients with decompensated liver cirrhosis. J Gastroenterol. 2010;45:979-987.
    • (2010) J Gastroenterol , vol.45 , pp. 979-987
    • Okita, K.1    Sakaida, I.2    Okada, M.3
  • 34
    • 33645089230 scopus 로고    scopus 로고
    • Vasopressin V2 receptor blockade with tolvaptan versus fluid restriction in the treatment of hyponatremia
    • Gheorghiade M, Gottlieb SS, Udelson JE, et al. Vasopressin V2 receptor blockade with tolvaptan versus fluid restriction in the treatment of hyponatremia. Am J Cardiol. 2006;7:1064-1067.
    • (2006) Am J Cardiol , vol.7 , pp. 1064-1067
    • Gheorghiade, M.1    Gottlieb, S.S.2    Udelson, J.E.3
  • 35
    • 33751005260 scopus 로고    scopus 로고
    • Tolvaptan, a selective oral vasopressin V2 receptor antagonist, for hyponatremia
    • Schrier RW, Gross P, Gheorghiade M, et al. Tolvaptan, a selective oral vasopressin V2 receptor antagonist, for hyponatremia. N Engl J Med. 2006;355:2099-2112.
    • (2006) N Engl J Med , vol.355 , pp. 2099-2112
    • Schrier, R.W.1    Gross, P.2    Gheorghiade, M.3
  • 36
    • 77950619540 scopus 로고    scopus 로고
    • Oral tolvaptan is safe and effective in chronic hyponatremia
    • Berl T, Quittnat-Pelletier F, Verbalis J, et al. Oral tolvaptan is safe and effective in chronic hyponatremia. J Am Soc Nephrol. 2010;21: 705-712.
    • (2010) J Am Soc Nephrol , vol.21 , pp. 705-712
    • Berl, T.1    Quittnat-Pelletier, F.2    Verbalis, J.3
  • 37
    • 56349152555 scopus 로고    scopus 로고
    • Double-blind, placebocontrolled, multicenter trial of a vasopressin V2 receptor antagonist in patients with schizophrenia and hyponatremia
    • Josiassen RC, Goldman M, Jessani M, et al. Double-blind, placebocontrolled, multicenter trial of a vasopressin V2 receptor antagonist in patients with schizophrenia and hyponatremia. Biol Psychiatry. 2008; 64:1097-1000.
    • (2008) Biol Psychiatry , vol.64 , pp. 1097-1000
    • Josiassen, R.C.1    Goldman, M.2    Jessani, M.3
  • 38
    • 0037904417 scopus 로고    scopus 로고
    • Vasopressin V2 receptor blockade with tolvaptan in patients with chronic heart failure, results from a double-blind, randomized trial
    • Gheorghiade M, Niazi I, Ouyang J, et al. Vasopressin V2 receptor blockade with tolvaptan in patients with chronic heart failure, results from a double-blind, randomized trial. Circulation. 2003;107:2690-2696.
    • (2003) Circulation , vol.107 , pp. 2690-2696
    • Gheorghiade, M.1    Niazi, I.2    Ouyang, J.3
  • 39
    • 0037326532 scopus 로고    scopus 로고
    • Rationale and study design for a multicenter, randomized, double-blind, placebo-controlled study of the effects of tolvaptan on the acute and chronic outcomes of patients hospitalized with worsening congestive heart failure
    • Gheorghiade M, Gattis WA, Barbagelata A. Rationale and study design for a multicenter, randomized, double-blind, placebo-controlled study of the effects of tolvaptan on the acute and chronic outcomes of patients hospitalized with worsening congestive heart failure. Am Heart J. 2003;145:S51-S54.
    • (2003) Am Heart J , vol.145
    • Gheorghiade, M.1    Gattis, W.A.2    Barbagelata, A.3
  • 40
    • 11144355788 scopus 로고    scopus 로고
    • Effects of tolvaptan, a vasopressin antagonist, in patients hospitalized with worsening heart failure: A randomized controlled trial
    • Gheorghiade M, Gattis WA, O'Connor C, et al. Effects of tolvaptan, a vasopressin antagonist, in patients hospitalized with worsening heart failure: a randomized controlled trial. JAMA. 2004;291:1963-1971.
    • (2004) JAMA , vol.291 , pp. 1963-1971
    • Gheorghiade, M.1    Gattis, W.A.2    O'Connor, C.3
  • 41
    • 20944445209 scopus 로고    scopus 로고
    • Rationale and design of the multicenter, randomized, double-blind, placebo-controlled study to evaluate the efficacy of vasopressin antagonism in heart failure: Outcome study with tolvaptan (EVEREST)
    • Gheorghiade M, Orlandi V, Burnett JC, et al. Rationale and design of the multicenter, randomized, double-blind, placebo-controlled study to evaluate the efficacy of vasopressin antagonism in heart failure: outcome study with tolvaptan (EVEREST). J Card Fail. 2005;11:260-269.
    • (2005) J Card Fail , vol.11 , pp. 260-269
    • Gheorghiade, M.1    Orlandi, V.2    Burnett, J.C.3
  • 42
    • 33947719178 scopus 로고    scopus 로고
    • Short-term clinical effects of tolvaptan, an oral vasopressin antagonist, in patients hospitalized for heart failure, the EVEREST clinical status trials
    • Gheorghiade M, Konstam MA, Burnett JC, et al. Short-term clinical effects of tolvaptan, an oral vasopressin antagonist, in patients hospitalized for heart failure, the EVEREST clinical status trials. JAMA. 2007;297:1332-1343.
    • (2007) JAMA , vol.297 , pp. 1332-1343
    • Gheorghiade, M.1    Konstam, M.A.2    Burnett, J.C.3
  • 43
    • 70349464874 scopus 로고    scopus 로고
    • Effects of tolvaptan on dyspnoea relief from the EVEREST trials
    • Pang PS, Konstam MA, Krasa HB, et al. Effects of tolvaptan on dyspnoea relief from the EVEREST trials. Eur Heart J. 2009;30:2233-2240.
    • (2009) Eur Heart J , vol.30 , pp. 2233-2240
    • Pang, P.S.1    Konstam, M.A.2    Krasa, H.B.3
  • 44
    • 54349103474 scopus 로고    scopus 로고
    • Acute hemodynamic effects of tolvaptan, a vasopressin V2 receptor blocker, in patients with symptomatic heart failure and systolic dysfunction: An international, multicenter, randomized, placebo-controlled trial
    • Udelson JE, Orlandi C, Ouyang J, et al. Acute hemodynamic effects of tolvaptan, a vasopressin V2 receptor blocker, in patients with symptomatic heart failure and systolic dysfunction: an international, multicenter, randomized, placebo-controlled trial. JACC. 2008;52:1540-1545.
    • (2008) JACC , vol.52 , pp. 1540-1545
    • Udelson, J.E.1    Orlandi, C.2    Ouyang, J.3
  • 45
    • 34249325160 scopus 로고    scopus 로고
    • Multicenter, randomized, double-blind, placebo-controlled study on the effect of oral tolvaptan on left ventricular dilation and function in patients with heart failure and systolic dysfunction
    • Udelson JE, McGrew FA, Flores E, et al. Multicenter, randomized, double-blind, placebo-controlled study on the effect of oral tolvaptan on left ventricular dilation and function in patients with heart failure and systolic dysfunction. JACC. 2007;49:2151-2159.
    • (2007) JACC , vol.49 , pp. 2151-2159
    • Udelson, J.E.1    McGrew, F.A.2    Flores, E.3
  • 46
    • 33644867235 scopus 로고    scopus 로고
    • Vasopressin- 2-receptor antagonism augments water excretion without changes in renal hemodynamics or sodium and potassium excretion in human heart failure
    • Costello-Boerrigter LC, Smith WB, Boerrigter G, et al. Vasopressin- 2-receptor antagonism augments water excretion without changes in renal hemodynamics or sodium and potassium excretion in human heart failure. Am J Physiol Renal Physiol. 2006;290:F273-F278.
    • (2006) Am J Physiol Renal Physiol , vol.290
    • Costello-Boerrigter, L.C.1    Smith, W.B.2    Boerrigter, G.3


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