Toxicity of a novel anti-tumor agent 20(S)-ginsenoside Rg3: A 26-week intramuscular repeated administration study in Beagle dogs

Food and Chemical Toxicology

Volumn 49, Issue 8, 2011, Pages 1718-1727

  Liu, J P ^a   Lu, D ^a   Nicholson, Richard C ^b,c   Li, P Y ^a   Wang, F ^d  

^a JILIN UNIVERSITY   (China)

^b UNIVERSITY OF NEWCASTLE   (Australia)

^c SECOND MILITARY MEDICAL UNIVERSITY   (China)

^d Basic Medical College   (China)

Author keywords

Beagle dogs; Chronic toxity; Intramuscular administration; Rg3

Indexed keywords

GINSENOSIDE RG 3;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOCHEMISTRY; BODY WEIGHT; BREATHING RATE; CLINICAL FEATURE; CONTROLLED STUDY; DOG; DOSE RESPONSE; ELECTROCARDIOGRAM; FEMALE; FOOD INTAKE; HEMATOLOGY; HISTOPATHOLOGY; LEUKOCYTE COUNT; LYMPHOCYTE COUNT; MALE; MORTALITY; NEUTROPHIL COUNT; NONHUMAN; OPHTHALMOSCOPY; ORGAN WEIGHT; REPEATED DRUG DOSE; TOXICITY TESTING; URINALYSIS;

ANIMALS; ANTINEOPLASTIC AGENTS; BODY WEIGHT; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; EATING; ELECTROCARDIOGRAPHY; FEMALE; GINSENOSIDES; INJECTIONS, INTRAMUSCULAR; LEUKOCYTE COUNT; MALE; NEUTROPHILS; NO-OBSERVED-ADVERSE-EFFECT LEVEL; OPHTHALMOSCOPY; ORGAN SIZE; TOXICITY TESTS, CHRONIC; URINALYSIS;

CANIS FAMILIARIS;

EID: 79958748932     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2011.04.017     Document Type: Article

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