An inhibitor of cAMP-dependent protein kinase induces behavioural and neurological antidepressant-like effects in rats

Neuroscience Letters

Volumn 498, Issue 2, 2011, Pages 158-161

  Liebenberg, Nico ^a   Müller, Heidi Kaastrup ^a   Fischer, Christina Weide ^a   Harvey, Brian H ^b   Brink, Christiaan B ^b   Elfving, Betina ^a   Wegener, Gregers ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b NORTH WEST UNIVERSITY   (South Africa)

Author keywords

CREB; Depression; Epac; Protein kinase A; Rp 8 Br cAMPS

Indexed keywords

ANTIDEPRESSANT AGENT; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; EPAC; GUANINE NUCLEOTIDE EXCHANGE FACTOR; RP 8 BR CAMP; UNCLASSIFIED DRUG;

ANALYSIS OF VARIANCE; ANIMAL EXPERIMENT; ANTIDEPRESSANT ACTIVITY; ARTICLE; BRAIN HOMOGENATE; CEREBELLUM; CONCENTRATION (PARAMETERS); DEPRESSION; DRUG ACTIVITY; EXPERIMENTAL TEST; FORCED SWIM TEST; FRONTAL CORTEX; HIPPOCAMPUS; IMMOBILIZATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT;

8-BROMO CYCLIC ADENOSINE MONOPHOSPHATE; ANIMALS; ANTIDEPRESSIVE AGENTS; BEHAVIOR, ANIMAL; CEREBELLUM; CYCLIC AMP; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYCLIC GMP; CYCLIC GMP-DEPENDENT PROTEIN KINASES; DEPRESSION; GUANINE NUCLEOTIDE EXCHANGE FACTORS; MALE; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; RATS; RATS, SPRAGUE-DAWLEY; SECOND MESSENGER SYSTEMS; SWIMMING; THIONUCLEOTIDES;

EID: 79958695938     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2011.05.004     Document Type: Article

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