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Expert Opinion on Therapeutic Targets
Volumn 15, Issue 7, 2011, Pages 785-788
Targeting mitotic exit for cancer treatment
Author keywords

anaphase promoting complex; antimitotic drugs; cyclin B; mitotic exit; proteasome; spindle assembly checkpoint; targeted therapy; ubiquitin
Indexed keywords

ANAPHASE PROMOTING COMPLEX; CYCLIN B;
EID: 79958294564     PISSN: 14728222     EISSN: 17447631     Source Type: Journal    
DOI: 10.1517/14728222.2011.577420     Document Type: Review
Times cited : (5)
References (8)
  • 1
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    • Structure of the anaphase-promoting complex/cyclosome interacting with a mitotic checkpoint complex
    • Herzog F, Primorac I, Dube P, et al. Structure of the anaphase-promoting complex/cyclosome interacting with a mitotic checkpoint complex. Science 2009;323:1477-81
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    • Herzog, F.1    Primorac, I.2    Dube, P.3
  • 2
    • 48449098623 scopus 로고    scopus 로고
    • Cancer cells display profound intra- and interline variation following prolonged exposure to antimitotic drugs
    • Gascoigne KE, Taylor SS. Cancer cells display profound intra- and interline variation following prolonged exposure to antimitotic drugs. Cancer Cell 2008;14:111-22
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    • Gascoigne, K.E.1    Taylor, S.S.2
  • 3
    • 70349452101 scopus 로고    scopus 로고
    • Evidence that mitotic exit is a better cancer therapeutic target than spindle assembly
    • Huang HC, Shi J, Orth JD, Mitchison TJ. Evidence that mitotic exit is a better cancer therapeutic target than spindle assembly. Cancer Cell 2009;16:347-58
    • (2009) Cancer Cell , vol.16 , pp. 347-58
    • Huang, H.C.1    Shi, J.2    Orth, J.D.3    Mitchison, T.J.4
  • 4
    • 78650004841 scopus 로고    scopus 로고
    • Targeting mitotic exit leads to tumor regression in vivo: Modulation by Cdk1, Mastl, and the PP2A/B55alpha,delta phosphatase
    • Manchado E, Guillamot M, de Carcer G, et al. Targeting mitotic exit leads to tumor regression in vivo: modulation by Cdk1, Mastl, and the PP2A/B55alpha,delta phosphatase. Cancer Cell 2010;18:641-54
    • (2010) Cancer Cell , vol.18 , pp. 641-54
    • Manchado, E.1    Guillamot, M.2    De Carcer, G.3
  • 6
    • 61449172876 scopus 로고    scopus 로고
    • Strong inducible knockdown of APC/CCdc20 does not cause mitotic arrest in human somatic cells
    • Baumgarten AJ, Felthaus J, Wasch R. Strong inducible knockdown of APC/CCdc20 does not cause mitotic arrest in human somatic cells. Cell Cycle 2009;8:643-6
    • (2009) Cell Cycle , vol.8 , pp. 643-6
    • Baumgarten, A.J.1    Felthaus, J.2    Wasch, R.3
  • 7
    • 79953793743 scopus 로고    scopus 로고
    • Inhibitory phosphorylation of CDK1 as a compensatory mechanism for mitosis exit
    • Chow JP, Poon RY, Ma HT. Inhibitory phosphorylation of CDK1 as a compensatory mechanism for mitosis exit. Mol Cell Biol 2011;31:1478-91
    • (2011) Mol Cell Biol , vol.31 , pp. 1478-91
    • Chow, J.P.1    Poon, R.Y.2    Ma, H.T.3
  • 8
    • 77957947338 scopus 로고    scopus 로고
    • Pharmacologic inhibition of the anaphase-promoting complex induces a spindle checkpoint-dependent mitotic arrest in the absence of spindle damage
    • Zeng X, Sigoillot F, Gaur S, et al. Pharmacologic inhibition of the anaphase-promoting complex induces a spindle checkpoint-dependent mitotic arrest in the absence of spindle damage. Cancer Cell 2010;18:382-95
    • (2010) Cancer Cell , vol.18 , pp. 382-95
    • Zeng, X.1    Sigoillot, F.2    Gaur, S.3

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.