Biomarkers of recent drinking, retrograde extrapolation of blood-alcohol concentration and plasma-to-blood distribution ratio in a case of driving under the influence of alcohol

Journal of Forensic and Legal Medicine

Volumn 18, Issue 5, 2011, Pages 213-216

  Jones, Alan Wayne ^a  

^a National Board of Forensic Medicine   (Sweden)

Author keywords

Alcohol; Back extrapolation; Biomarkers; Drunk driving; Ethanol; Ethyl glucuronide; Plasma blood ratio; Traffic crash

Indexed keywords

2 PROPANOL; BIOLOGICAL MARKER; ETHYL GLUCURONIDE;

ALCOHOL BLOOD LEVEL; ALCOHOL CONSUMPTION; ARTICLE; BLOOD SAMPLING; CAR DRIVER; CAR DRIVING; CASE REPORT; CLINICAL LABORATORY; EMERGENCY TREATMENT; FORENSIC TOXICOLOGY; GAS CHROMATOGRAPHY; HUMAN; LIMIT OF QUANTITATION; MALE; MEASUREMENT ERROR; POLICE; TRAFFIC ACCIDENT;

2-PROPANOL; ACCIDENTS, TRAFFIC; ALCOHOL DRINKING; AUTOMOBILE DRIVING; BIOLOGICAL MARKERS; CATHETERS; CENTRAL NERVOUS SYSTEM DEPRESSANTS; CHROMATOGRAPHY, GAS; DISINFECTANTS; ETHANOL; FEMALE; FORENSIC TOXICOLOGY; GLUCURONATES; HUMANS; PLASMA; SULFURIC ACID ESTERS;

EID: 79958289387     PISSN: 1752928X     EISSN: 18787487     Source Type: Journal    
DOI: 10.1016/j.jflm.2011.02.011     Document Type: Article

References (34)

1. R.C. Peck, M.A. Gebers, R.B. Voas, and E. Romano The relationship between blood alcohol concentration (BAC), age, and crash risk J Safety Res 39 2008 311 319
2. A.W. Jones, F.C. Kugelberg, A. Holmgren, and J. Ahlner Five year update on the occurrence of alcohol and other drugs in blood samples from drivers killed in road-traffic crashes in Sweden Forensic Sci Int 188 2009 56 62
3. A.W. Jones Blood and breath alcohol concentrations BMJ 305 1992 955
4. A.W. Jones, and L. Andersson Comparison of ethanol concentrations in venous blood and end-expired breath during a controlled drinking experiment Forensic Sci Int 132 2003 18 25 (Pubitemid 36411644)
5. A.W. Jones Top-tendefence challenges among drinking drivers in Sweden Med Sci Law 31 1991 229 238
6. R.G. Gullberg Common legal challenges and responses in forensic breath alcohol determination Forensic Sci Rev 16 2004 91 101
7. R.B. Voas Enforcement of DUI laws Alc Drugs Driving 7 1991 173 196
8. A.W. Jones Enforcement of drink-driving laws by use of "per se" legal alcohol limits: blood and/or breath concentration as evidence of impairment Alc Drugs Driving 4 1988 99 112
9. P.M. Rainey Alcohol testing in the clinical laboratory - alternative remedies Clin Chem 39 1993 2538 2539
10. P.M. Rainey Relation between serum and whole-blood ethanol concentrations Clin Chem 39 1993 2288 2292 (Pubitemid 23333321)
11. M.T. Barnhill, D. Herbert, and D.J. Wells Comparison of hospital laboratory serum alcohol levels obtained by an enzymatic method with whole blood levels forensically determined by gas chromatography J Anal Toxicol 31 2007 23 30 (Pubitemid 46376970)
12. A.W. Jones, R.G. Hahn, and H.P. Stalberg Distribution of ethanol and water between plasma and whole blood; inter- and intra-individual variations after administration of ethanol by intravenous infusion Scand J Clin Lab Invest 50 1990 775 780 (Pubitemid 20369266)
13. R.C. Charlebois, M.R. Corbett, and J.G. Wigmore Comparison of ethanol concentrations in blood, serum, and blood cells for forensic applications J Anal Toxicol 20 1966 171 178
14. R.J.R. Beijering, C.H. Gips, J.R. Huizenga, J. Jager, A.J. Mackor, and H. Salomons Whole blood and plasma water in health and disease: longitudinal and transverse observations and correlations with several different hematological and clinico-chemical parameters Clin Chim Acta 258 1997 59 68 (Pubitemid 27064029)
15. J.D. Artiss, and B. Zak Problems with measurements caused by high concentrations of serum solids CRC Crit Rev Clin Lab Sci 25 1987 19 41
16. A.W. Jones Dealing with uncertainty in chemical measurements IACT Newslett 14 2003 6 11
17. A.W. Jones, A.W. Jones, M. Falkensson, and L. Nilsson Reliability of blood-alcohol determinations at clinical chemistry laboratories in Sweden Scand J Clin Lab Invest 55 1995 463 468
18. C.L. Winek, and M. Carfagna Comparison of plasma, serum, and whole blood ethanol concentrations J Anal Toxicol 11 1987 267 268 (Pubitemid 17166287)
19. A.W. Jones, R. Hahn, and H.P. Stalberg Pharmacokinetics of ethanol in plasma and whole blood; estimation of total body water by the dilution principle Eur J Clin Pharmacol 42 1992 445 448
20. R. Iffland, A. West, N. Bilzer, and A. Schuff Zur Zuverlässigkeit der Blutalkoholbestimmung. Das Verteilungsverhältnis des Wassers zwischen Serum und Vollblut Rechtsmedizin 9 1999 123 130 (Pubitemid 29282608)
21. A.W. Jones Evidence based survey of the elimination rates of ethanol from blood with applications in forensic casework Forensic Sci Int 200 2010 1 20
22. G.J. Peek, A. Marsh, J. Keating, R.J. Ward, and T.J. Peters The effects of swabbing the skin on apparent blood alcohol concentration Alcohol Alcohol 25 1990 639 640
23. K.W. Ryder, and M.R. Glick The effect of skin cleansing agents on ethanol results measured with the Du Pont automatic clinical analyzer J Forensic Sci 31 1986 574 579 (Pubitemid 16016376)
24. T.M. Goldfinger, D. Pennsylvania, and D. Schaber A comparison of blood alcohol concentration using non-alcohol and alcohol containing skin antiseptics Ann Emerg Med 11 1982 665 667 (Pubitemid 13172006)
25. R.A. McIvor, and S.H. Cosbey Effect of using alcoholic and non-alcoholic skin cleansing swabs when sampling blood for alcohol estimation using gas chromatography Br J Clin Pract 44 1992 235 236 (Pubitemid 20204720)
26. M. Malingre, T. Ververs, S. Bos, C. Van Kestern, and H. Van Rijn Alcohol swabs and venipuncture in a routine hospital setting: no effect on blood ethanol measurement Ther Drug Monitor 27 2005 403 404 (Pubitemid 40771000)
27. A.W. Jones, and J. Schuberth Computer-aided headspace gas chromatography applied to blood-alcohol analysis; importance of on-line process control J Forensic Sci 34 1989 1116 1127 (Pubitemid 19236090)
28. th ed. 2008 Lawyers & Judges Publishing Co., Inc. Tucson 157 204
29. A. Helander, M. Böttcher, C. Fehr, N. Dahmen, and O. Beck Detection times for urinary ethyl glucuronide and ethyl sulphate in heavy drinkers during alcohol detoxification Alcohol Alcohol 44 2008 55 61
30. P.R. Jackson, G.T. Tucker, and H.F. Woods Backtracking booze with Bayes - the retrograde interpretation of blood alcohol data Br J Clin Pharmacol 31 1991 55 63
31. K.O. Lewis Back calculation of blood alcohol concentration BMJ 295 1987 800 801 (Pubitemid 17153365)
32. A.R. Stowell, and L.I. Stowell Estimation of blood alcohol concentrations after social drinking J Forensic Sci 43 1998 14 21 (Pubitemid 28063699)
33. Y. Al-Lanqawi, T.A. Moreland, J. McEwan, F. Halliday, C.T. Durnin, and I.H. Stevenson Ethanol kinetics: extent of error in back calculation Br J Clin Pharmacol 34 1992 316 321
34. A.W. Jones Back-estimation of blood-alcohol concentration Br J Clin Pharmacol 35 1993 669 670