Process evaluations and economic analyses of recombinant human lysozyme and hen egg-white lysozyme purifications

Biotechnology Progress

Volumn 27, Issue 3, 2011, Pages 733-743

  Wilken, Lisa R ^a   Nikolov, Zivko L ^a  

^a Texas A and M University   (United States)

Author keywords

Hen egg white lysozyme; Human lysozyme; Process economics; Protein purification; Transgenic rice

Indexed keywords

HEN EGG WHITE LYSOZYME; HUMAN LYSOZYME; PROCESS ECONOMICS; PROTEIN PURIFICATION; TRANSGENIC RICE;

ADSORPTION; COST ACCOUNTING; COST BENEFIT ANALYSIS; ECONOMIC ANALYSIS; GEL PERMEATION CHROMATOGRAPHY; IONIC STRENGTH; PH EFFECTS; PURIFICATION;

ENZYMES;

CATION EXCHANGE RESIN; HEN EGG LYSOZYME; LYSOZYME; RECOMBINANT PROTEIN;

ADSORPTION; ANIMAL; ARTICLE; BIOSYNTHESIS; COMPARATIVE STUDY; COST; ECONOMICS; GENETICS; HUMAN; ISOLATION AND PURIFICATION; PROTEIN BINDING; RICE;

ADSORPTION; ANIMALS; CATION EXCHANGE RESINS; COSTS AND COST ANALYSIS; HUMANS; MURAMIDASE; ORYZA SATIVA; PROTEIN BINDING; RECOMBINANT PROTEINS;

EID: 79958280761     PISSN: 87567938     EISSN: 15206033     Source Type: Journal    
DOI: 10.1002/btpr.593     Document Type: Article

References (46)

1. Jollès P, editor. Lysozymes: Model Enzymes in Biochemistry and Biology. Basel, Switzerland: Birkhäuser Verlag; 1996.
2. Huang JM, Wu LY, Yalda D, Adkins Y, Kelleher SL, Crane M, Lonnerdal B, Rodriguez RL, Huang N. Expression of functional recombinant human lysozyme in transgenic rice cell culture. Transgenic Res. 2002; 11: 229-239.
3. Faure A, Jollès P. Lack of concordance between primary structure and antigenicity in the case of various lysozymes and of bovine alpha-lactalbumin. FEBS Lett. 1970; 10: 237-240.
4. Huang N, Rodriguez RL, Hagie FE. Expression of human milk proteins in transgenic plants. U.S. Patent 6, 991, 824, 2006.
5. Huang JM, Nandi S, Wu LY, Yalda D, Bartley G, Rodriguez R, Lonnerdal B, Huang N. Expression of natural antimicrobial human lysozyme in rice grains. Mol Breed. 2002; 10: 83-94.
6. Phillips JC. Scaling and self-organized criticality in proteins: lysozyme c. Phys Rev E. 2009; 80: 051916 (1-8).
7. Arnheim N, Prager EM, Wilson AC. Immunological prediction of sequence differences among proteins. J Biol Chem. 1969; 244: 2085-2094.
8. Cook ME. Antibodies: alternatives to antibiotics in improving growth and feed efficiency. J Appl Poult Res. 2004; 13: 106-119.
9. Proctor VA, Cunningham FE. The chemistry of lysozyme and its use as a food preservative and a pharmaceutical. CRC Crit Rev Food Sci Nutr. 1988; 26: 359-395.
10. Sava G. Pharmacological aspects and therapeutic applications of lysozymes. In: Jollès P, editor. Lysozymes: Model Enzymes in Biochemistry and Biology. Basel, Switzerland: Birkhäuser Verlag; 1996: 433-449.
11. Huang N, Huang J, Bethell DR. Method of making anti-infective composition for treating oral infections. U.S. Patent 7, 138, 150, 2006.
12. Hennegan KD, Yang C, Nguyen D, Wu LY, Goding J, Huang JM, Guo FL, Huang H, Watkins S. Improvement of human lysozyme expression in transgenic rice grain by combining wheat (Triticum aestivum) puroindoline b and rice (Oryza sativa) Gt1 promoters and signal peptides. Transgenic Res. 2005; 14: 583-592.
13. Li-Chan E, Nakai S, Sim J, Bragg DB, Lo KV. Lysozyme separation from egg-white by cation-exchange column chromatography. J Food Sci. 1986; 51: 1032-1036.
14. Guérin-Dubiard C, Pasco M, Hietanen A, del Bosque AQ, Nau F, Croguennec T. Hen egg white fractionation by ion-exchange chromatography. J Chromatogr. 2005; 1090: 58-67.
15. Alderton G, Ward WH, Fevold HL. Isolation of lysozyme from egg white. J Biol Chem. 1945; 157: 43-58.
16. Alderton G, Fevold HL. Direct crystallization of lysozyme from egg white and some crystalline salts of lysozyme. J Biol Chem. 1946; 164: 1-5.
17. Dismer F, Hubbuch J. A novel approach to characterize the binding orientation of lysozyme on ion-exchange resins. J Chromatogr. 2007; 1149: 312-320.
18. Carta G, Ubiera AR, Pabst TM. Protein mass transfer kinetics in ion exchange media: measurements and interpretations. Chem Eng Technol. 2005; 28: 1252-1264.
19. Dziennik SR, Belcher EB, Barker GA, Lenhoff AM. Effects of ionic strength on lysozyme uptake rates in cation exchangers. I: uptake in SP sepharose FF. Biotechnol Bioeng. 2005; 91: 139-153.
20. Ladiwala A, Rege K, Breneman CM, Cramer SM. A priori prediction of adsorption isotherm parameters and chromatographic behavior in ion-exchange systems. Proc Natl Acad Sci USA. 2005; 102: 11710-11715.
21. Chang C, Lenhoff AM. Comparison of protein adsorption isotherms and uptake rates in preparative cation-exchange materials. J Chromatogr A. 1998; 827: 281-293.
22. Nash DC, Chase HA. Comparison of diffusion and diffusion-convection matrices for use in ion-exchange separations of proteins. J Chromatogr. 1998; 807: 185-207.
23. Skidmore GL, Horstmann BJ, Chase HA. Modeling single-component protein adsorption to the cation exchanger S sepharose FF. J Chromatogr. 1990; 498: 113-128.
24. Whitley RD, Wachter R, Liu F, Wang NHL. Ion-exchange equilibria of lysozyme, myoglobin and bovine serum albumin: effective valence and exchanger capacity. J Chromatogr. 1989; 465: 137-156.
25. Bradford MM. Rapid and sensitive method for quantitation of microgram quantities of protein utilizing principle of protein-dye binding. Anal Biochem. 1976; 72: 248-254.
26. Shugar D. The measurement of lysozyme activity and the ultra-violet inactivation of lysozyme. Biochim Biophys Acta. 1952; 8: 302-309.
27. Rea TH, Taylor CR. Serum and tissue lysozyme in leprosy. Infect Immun. 1977; 18: 847-56.
28. Pace CN, Vajdos F, Fee L, Grimsley G, Gray T. How to measure and predict the molar absorption coefficient of a protein. Protein Sci. 1995; 4: 2411-2423.
29. Laemmli UK. Cleavage of structural proteins during assembly of head of bacteriophage T4. Nature. 1970; 227: 680-685.
30. Nakamura R, Sato Y, Yoshikawa K. Studies on the foaming property of the chicken egg white. Part IV. On the method of preparing ovomucin. J Agric Chem Soc Jpn. 1961; 35: 636-641.
31. Peters MS, Timmerhaus KD. Plant Design and Economics for Chemical Engineers, 4th ed. New York: McGraw-Hill; 1991.
32. Harrison RG, Todd P, Rudge SR, Petrides DP. Bioseparations Science and Engineering. New York: Oxford University Press; 2003.
33. Zydney AL, Harinarayan C, van Reis R. Modeling electrostatic exclusion effects during ion exchange chromatography of monoclonal antibodies. Biotechnol Bioeng. 2009; 102: 1131-1140.
34. Zhang C, Glatz CE. Process engineering strategy for recombinant protein recovery from canola by cation exchange chromatography. Biotechnol Prog. 1999; 15: 12-18.
35. Martz E. Protein explorer: easy yet powerful macromolecular visualization. Trends Biochem Sci. 2002; 27: 107-109.
36. Wilken LR, Nikolov ZL. Factors influencing recombinant human lysozyme extraction and cation exchange adsorption. Biotechnol Prog. 2006; 22: 745-752.
37. Cheryan M. Phytic acid interactions in food systems. CRC Crit Rev Food Sci Nutr. 1980; 13: 297-335.
38. Wilken L, Nikolov Z. Evaluation of alternatives for human lysozyme purification from transgenic rice: impact of phytic acid and buffer. Biotechnol Prog. 2010; 26: 1303-1311.
39. Stevens L. Egg white proteins. Comp Biochem Physiol B Biochem Mol Biol. 1991; 100: 1-9.
40. Menkhaus TJ, Bai Y, Zhang CM, Nikolov ZL, Glatz CE. Considerations for the recovery of recombinant proteins from plants. Biotechnol Prog. 2004; 20: 1001-1014.
41. Safarik I, Sabatkova Z, Tokar O, Safarikova M. Magnetic cation exchange isolation of lysozyme from native hen egg white. Food Technol Biotechnol. 2007; 45: 355-359.
42. Lesnierowski G, Kijowski J. Lysozyme. In: Huopalahti R, López-Fandiño R, Anton M, Schade R, editors. Bioactive Egg Compounds. New York: Springer; 2007: 33-42.
43. Gottschalk U. Bioseparation in antibody manufacturing: the good, the bad and the ugly. Biotechnol Prog. 2008; 24: 496-503.
44. Nikolov Z, Hammes D. Production of recombinant proteins from transgenic crops. In: Hood EE, Howard JA, editors. Plants as Factories for Protein Production. Dordrecht, The Netherlands: Kluwer Academic Publishers; 2002: 159-174.
45. Kalaitzandonakes N, Alston JM, Bradford KJ. Compliance costs for regulatory approval of new biotech crops. Nat Biotechnol. 2007; 25: 509-511.
46. Sparrow PAC, Twyman RM. Biosafety, risk assesssment and regulation of plant-made pharmaceuticals. In: Faye L, Gomord V, editors. Recombinant Proteins from Plants. New York: Humana Press; 2009: 341-353.