Effects of rat C-peptide-II on lipolysis and glucose consumption in cultured rat adipose tissue

Experimental and Clinical Endocrinology and Diabetes

Volumn 119, Issue 6, 2011, Pages 343-347

  Ghorbani, A ^a,b   Omrani, G R ^c   Hadjzadeh, M Al R ^d   Varedi, M ^a,e  

^a SHIRAZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b MASHHAD UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c SHIRAZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^d MASHHAD UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^e SHIRAZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

adipose tissue; C peptide; lipolysis; metabolism; rat

Indexed keywords

C PEPTIDE; GLUCOSE; GLYCEROL; INSULIN; ISOPRENALINE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CULTURE MEDIUM; EX VIVO STUDY; GLUCOSE INTAKE; LIPOLYSIS; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RETROPERITONEAL FAT; TISSUE CULTURE;

ADIPOSE TISSUE; ANIMALS; C-PEPTIDE; CELL SURVIVAL; CELLS, CULTURED; DRUG EVALUATION, PRECLINICAL; ENDOTHELIAL CELLS; GLUCOSE; INSULIN; LIPOLYSIS; MALE; RATS; RATS, SPRAGUE-DAWLEY; STROMAL CELLS;

EID: 79958273965     PISSN: 09477349     EISSN: 14393646     Source Type: Journal    
DOI: 10.1055/s-0031-1275662     Document Type: Article

References (32)

1. Wahren J, Ekberg K, Jornvall H. C-peptide is a bioactive peptide. Diabetologia 2007 50 503-509 (Pubitemid 46215490)
2. Wahren J. C-peptide: new findings and therapeutic implications in diabetes. Clin Physiol Funct Imaging 2004 24 180-189 (Pubitemid 39089034)
3. +-ATPase activity via PKC alpha in rat medullary thick ascending limb. Diabetologia 2003 46 124-131 (Pubitemid 36237755)
4. Wallerath T, Kunt T, Forst T et al,. Stimulation of endothelial nitric oxide synthase by proinsulin C-peptide. Nitric oxide 2003 9 95-102 (Pubitemid 37386378)
5. ++ increases in human renal tubular cells. Cell Mol Life Sci 2002 59 1185-1189
6. Nordquist L, Palm F, Andresen TB. Renal and vascular benefits of C-peptide: Molecular mechanisms of C-peptide action. Biologics 2008 2 441-452
7. Uruska A, Araszkiewicz A, Zozulinska-Ziolkiewicz D et al,. Insulin resistance is associated with microangiopathy in type 1 diabetic patients treated with intensive insulin therapy from the onset of disease. Exp Clin Endocrinol Diabetes 2010 118 478-484
8. Wu W, Oshida Y, Yang WP et al,. Effect of C-peptide administration on whole body glucose utilization in STZ-induced diabetic rats. Acta Physiol Scand 1996 157 253-258 (Pubitemid 26178822)
9. Zierath JR, Handberg A, Tally M et al,. C-peptide stimulates glucose transport in isolated human skeletal muscle independent of insulin receptor and tyrosine kinase activation. Diabetologia 1996 39 306-313 (Pubitemid 26066802)
10. Zierath JR, Galuska D, Johansson BL et al,. Effect of human C-peptide on glucose transport in in vitro incubated human skeletal muscle. Diabetologia 1991 34 899-901
11. Johansson BL, Sjoberg S, Wahren J. The influence of human C-peptide on renal function and glucose utilization in type 1 (insulin-dependent) diabetic patients. Diabetologia 1992 35 121-128
12. Grunberger G, Qiang X, Li Z et al,. Molecular basis for the insulinomimetic effects of C-peptide. Diabetologia 2001 44 1247-1257 (Pubitemid 33010501)
13. Rigler R, Pramanik A, Jonasson P et al,. Specific binding of proinsulin C-peptide to human cell membranes. PNAS 1999 96 13318-13323
14. Ido Y, Vindigni A, Chang K et al,. Prevension of vascular and nural dysfunction in diabetic rats by C-peptide. Sience 1997 277 563-566 (Pubitemid 27369004)
15. Arner P. Human fat cell lipolysis: Biochemistry, regulation and clinical role. Best Pract Res Clin Endocrinol Metab 2005 19 471-482 (Pubitemid 41819214)
16. Adachi Y, Sakurai H. Insulin-mimetic vanadyl(IV) complexes as evaluated by both glucose-uptake and inhibition of free fatty acids (FFA) release in isolated rat adipocytes. Chem Pharm Bull 2004 52 428-433 (Pubitemid 41694727)
17. Accorsi PA, Gamberoni M, Isani G et al,. Leptin does not seem to influence glucose uptake by bovine mammary explants. J Physiol Pharmacol 2005 56 689-698 (Pubitemid 43127563)
18. Moustaid N, Jones BH, Taylor JW. Insulin increase lipogenic enzyme activity in human adipocytes in primary culture. J Nutr 1996 126 865-870 (Pubitemid 26100956)
19. Rodbell M. Metabolism of isolated fat cells. I. Effects of hormones on glucose metabolism and lipolysis. J Biol Chem 1964 239 375-380
20. Nakano T, Scott PG. Purification and characterization of gelatinase produced by fibroblasts from human gingival. Biochem Cell Biol 1986 64 387-393 (Pubitemid 16089032)
21. Kitabchi AE. The biological and immunological properties of pork and beef insulin, proinsulin, and connecting peptides. J Clin Inves 1970 49 979-987
22. Solomon SS, Brush JS, Kitabchi AE. Antilipolytic activity of insulin and proinsulin on ACTH and cyclic nucleotide-induced lipolysis in the isolated adipose cell of rat. Biochem Biophys Acta 1970 218 167-169
23. Yu SS, Kitabchi AE. Biological activity of proinsulin and related polypeptides in the fat tissue. J Biol Chem 1973 248 3753-3761
24. Steiner DF, Bell GI, Rubenstein AH et al,. Chemistry and biosynthesis of the islet hormones. In: DeGroot L, Jameson JL Endocrinology 5th ed. Philadelphia Elsevier 2006 925-960
25. Grunberger G, Sima AAF. The C-peptide signaling. Exp Diab Res 2004 5 25-36 (Pubitemid 38488733)
26. Horwitz DL, Starr JI, Mako ME et al,. Proinsulin, insulin, and C-peptide concentrations in human portal and peripheral blood. J Clin Invest 1975 55 1278-1283 (Pubitemid 8036490)
27. Wahren J, Ekberg K, Johansson J et al,. Role of C-peptide in human physiology. Am J Physiol Endocrinol Metab 2000 278 759-768
28. Ghorbani A, Varedi M, Hadjzadeh MA et al,. Type-1 diabetes induces depot-specific alterations in adipocyte diameter and mass of adipose tissues in the rat. Exp Clin Endocrinol Diabetes 2010 118 442-448
29. Varedi M, Tredget EE, Ghahary A et al,. Stress-relaxation and contraction of a collagen matrix induces expression of TGF- and triggers apoptosis in dermal fibroblasts. Biochem Cell Biol 2000 78 427-436
30. Foster DW, Esser V. Ketoacidosis and hyperosmolar coma. In: DeGroot L, Jameson JL, editors. Endocrinology 5 th ed. Philadelphia Elsevier 2006 1185-1195
31. Kunt T, Schneider S, Pfutzner A et al,. The effect of human proinsulin C-peptide on erythrocyte deformability in patients with Type I diabetes mellitus. Diabetologia 1999 42 465-471 (Pubitemid 29148406)
32. Nordquist L, Moe E, Sjoquist M. The C-peptide fragment EVARQ reduces glomerular hyperfiltration in streptozotocin induced diabetic rats. Diabetes Metab Res Rev 2007 23 400-405 (Pubitemid 47091244)