Determination of SYUIQ-F5, a novel telomerase inhibitor and anti-tumor lead-compound, in tissues and plasma samples by LC-MS-MS: Application to a tissue distribution study in rat

Chromatographia

Volumn 73, Issue 11-12, 2011, Pages 1073-1080

  Xiong, Huiyu ^a   Bi, Huichang ^a   Wen, Yuguang ^b   Hu, Jinqing ^a   Zhong, Guoping ^a   Ou, Tianmiao ^a   Huang, Zhishu ^a   Liao, Rifang ^a   Zhao, Minjing ^a   Qin, Xiaoling ^a   Huang, Min ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b Guangzhou Brain Hospital   (China)

Author keywords

Liquid chromatography tandem mass spectrometry (LC MS MS); SYUIQ F5; Tissue distribution

Indexed keywords

11 CHLORO 7 FLUORO 10H INDOLO[3,2 B]QUINOLINE; ACETIC ACID ETHYL ESTER; ACETONITRILE; ANTINEOPLASTIC AGENT; DICHLOROMETHANE; FAT; N [3 (DIMETHYLAMINO)PROPYL] 7 FLUORO 10H INDOLO[3,2 B]QUINOLON 11 AMINE; ORGANOLEAD COMPOUND; SYUIQ F5; TELOMERASE INHIBITOR; UNCLASSIFIED DRUG;

ACCURACY; ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; BRAIN; CONTROLLED STUDY; DRUG TISSUE LEVEL; ELECTROSPRAY; FLOW RATE; HEART; KIDNEY; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; LIVER; LUNG; MALE; MUSCLE; NONHUMAN; PLASMA; PRIORITY JOURNAL; RAT; RELIABILITY; SENSITIVITY AND SPECIFICITY; SINGLE DRUG DOSE; SMALL INTESTINE; SPLEEN; STOMACH; TANDEM MASS SPECTROMETRY; TESTIS; TISSUE DISTRIBUTION; VALIDATION PROCESS;

EID: 79958273136     PISSN: 00095893     EISSN: 16121112     Source Type: Journal    
DOI: 10.1007/s10337-011-1998-2     Document Type: Article

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