Gait variability is associated with frailty in community-dwelling older adults

Journals of Gerontology - Series A Biological Sciences and Medical Sciences

Volumn 66 A, Issue 5, 2011, Pages 568-576

  Montero Odasso, Manuel ^a,b   Muir, Susan W ^a   Hall, Maggie ^c   Doherty, Timothy J ^a,b   Kloseck, Marita ^a   Beauchet, Olivier ^d   Speechley, Mark ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b LAWSON HEALTH RESEARCH INSTITUTE   (Canada)

^c PARKWOOD HOSPITAL   (Canada)

^d ANGERS UNIVERSITY HOSPITAL   (France)

Author keywords

Aged; Disability; Frailty; Gait; Variability

Indexed keywords

AGED; ARTICLE; CROSS-SECTIONAL STUDY; FEMALE; FRAIL ELDERLY; GAIT; HUMAN; INDEPENDENT LIVING; MALE; PHYSIOLOGY;

AGED, 80 AND OVER; CROSS-SECTIONAL STUDIES; FEMALE; FRAIL ELDERLY; GAIT; HUMANS; INDEPENDENT LIVING; MALE;

EID: 79958264790     PISSN: 10795006     EISSN: 1758535X     Source Type: Journal    
DOI: 10.1093/gerona/glr007     Document Type: Article

References (51)

1. Fried LP, Tangen CM, Walston J, et al. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci. 2001;56:M146-M156. (Pubitemid 32187141)
2. Gill TM, McGloin JM, Gahbauer EA, Shepard DM, Bianco LM. Two recruitment strategies for a clinical trial of physically frail community-living older persons. J Am Geriatr Soc. 2001;49:1039-1045. (Pubitemid 32801140)
3. Rothman MD, Leo-Summers L, Gill TM. Prognostic significance of potential frailty criteria. J Am Geriatr Soc. 2008;56:2211-2216.
4. Cesari M, Kritchevsky SB, Penninx BW, et al. Prognostic value of usual gait speed in well-functioning older people-results from the Health, Aging and Body Composition Study. J Am Geriatr Soc. 2005; 53:1675-1680. (Pubitemid 43109929)
5. Montero-Odasso M, Schapira M, Varela C, et al. Gait velocity in senior people. An easy test for detecting mobility impairment in community elderly. J Nutr Health Aging. 2004;8:340-343. (Pubitemid 39273802)
6. Montero-Odasso M, Schapira M, Soriano ER, et al. Gait velocity as a single predictor of adverse events in healthy seniors aged 75 years and older. J Gerontol A Biol Sci Med Sci. 2005;60:1304-1309. (Pubitemid 41612425)
7. Newell KM CDM. Issues in variability and motor control. In: KM Newell and DM Corcos (eds). Variability and Motor Control, 1993 Ed. Champaign, IL: Human Kinetics; 2010:1-12.
8. Hausdorff JM. Gait variability: methods, modeling and meaning. J Neuroeng Rehabil. 2005;2:19.
9. Brach JS, Studenski SA, Perera S, VanSwearingen JM, Newman AB. Gait variability and the risk of incident mobility disability in community-dwelling older adults. J Gerontol A Biol Sci Med Sci. 2007;62: 983-988. (Pubitemid 47531214)
10. Brach JS, Perera S, Studenski S, Newman AB. The reliability and validity of measures of gait variability in community-dwelling older adults. Arch Phys Med Rehabil. 2008;89:2293-2296.
11. Herman T, Mirelman A, Giladi N, Schweiger A, Hausdorff JM. Executive control deficits as a prodrome to falls in healthy older adults: a prospective study linking thinking, walking, and falling. J Gerontol A Biol Sci Med Sci. 2010;65:1086-1092.
12. Verghese J, Holtzer R, Lipton RB, Wang C. Quantitative gait markers and incident fall risk in older adults. J Gerontol A Biol Sci Med Sci. 2009;64:896-901.
13. Hausdorff JM, Rios DA, Edelberg HK. Gait variability and fall risk in community-living older adults: a 1-year prospective study. Arch Phys Med Rehabil. 2001;82:1050-1056. (Pubitemid 32744331)
14. Hausdorff JM. Gait dynamics, fractals and falls: finding meaning in the stride-to-stride fluctuations of human walking. Hum Mov Sci. 2007;26:555-589. (Pubitemid 47324190)
15. Kressig RW, Gregor RJ, Oliver A, et al. Temporal and spatial features of gait in older adults transitioning to frailty. Gait Posture. 2004;20:30-35. (Pubitemid 38758025)
16. Kloseck M, Crilly RG, Mannell RC. Involving the community elderly in the planning and provision of health services: predictors of volunteerism and leadership. Can J Aging. 2006;25:77-91. (Pubitemid 43835460)
17. American Geriatrics Society, British Geriatrics Society, and American Academy of Orthopaedic Surgeons Panel on Falls Prevention. Guideline for the prevention of falls in older persons. J Am Geriatr Soc. 2001;49:664-672.
18. Cumming RG, Kelsey JL, Nevitt MC. Methodologic issues in the study of frequent and recurrent health problems. Falls in the elderly. Ann Epidemiol. 1990;1:49-56.
19. Lach HW, Reed AT, Arfken CL, et al. Falls in the elderly: reliability of a classification system. J Am Geriatr Soc. 1991;39:197-202.
20. Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987;40:373-383. (Pubitemid 17055592)
21. Gill TM, Baker DI, Gottschalk M, Peduzzi PN, Allore H, Van Ness PH. A prehabilitation program for the prevention of functional decline: effect on higher-level physical function. Arch Phys Med Rehabil. 2004; 85:1043-1049. (Pubitemid 38962358)
22. Abellan VK, Rolland Y, Andrieu S, et al. Gait speed at usual pace as a predictor of adverse outcomes in community-dwelling older people an International Academy on Nutrition and Aging (IANA) Task Force. J Nutr Health Aging. 2009;13:881-889.
23. Washburn RA, Smith KW, Jette AM, Janney CA. The Physical Activity Scale for the Elderly (PASE): development and evaluation. J Clin Epidemiol. 1993;46:153-162. (Pubitemid 23092124)
24. Orme JG, Reis J, Herz EJ. Factorial and discriminant validity of the Center for Epidemiological Studies Depression (CES-D) scale. J Clin Psychol. 1986;42:28-33. (Pubitemid 16188206)
25. Verghese J, Xue X. Identifying frailty in high functioning older adults with normal mobility. Age Ageing. 2010;39:382-385.
26. Ensrud KE, Ewing SK, Taylor BC, et al. Comparison of 2 frailty indexes for prediction of falls, disability, fractures, and death in older women. Arch Intern Med. 2008;168:382-389. (Pubitemid 351347130)
27. Bilney B, Morris M, Webster K. Concurrent related validity of the GAITRite walkway system for quantification of the spatial and temporal parameters of gait. Gait Posture. 2003;17:68-74. (Pubitemid 36132191)
28. Menz HB, Latt MD, Tiedemann A, Mun SK, Lord SR. Reliability of the GAITRite walkway system for the quantification of temporo-spatial parameters of gait in young and older people. Gait Posture. 2004;20:20-25. (Pubitemid 38758023)
29. Montero-Odasso M, Casas A, Hansen KT, et al. Quantitative gait analysis under dual-task in older people with mild cognitive impairment: a reliability study. J Neuroeng Rehabil. 2009;6:35.
30. Youdas JW, Hollman JH, Aalbers MJ, Ahrenholz HN, Aten RA, Cremers JJ. Agreement between the GAITRite walkway system and a stopwatch-footfall count method for measurement of temporal and spatial gait parameters. Arch Phys Med Rehabil. 2006;87:1648-1652. (Pubitemid 44821075)
31. Hausdorff JM. Stride variability: beyond length and frequency. Gait Posture. 2004;20:304.
32. Alexander NB. Gait disorders in older adults. J Am Geriatr Soc. 1996;44:434-451. (Pubitemid 26115560)
33. Lipsitz LA. Dynamics of stability: the physiologic basis of functional health and frailty. J Gerontol A Biol Sci Med Sci. 2002;57: B115-B125. (Pubitemid 34202932)
34. Lipsitz LA. Physiological complexity, aging, and the path to frailty. Sci Aging Knowledge Environ. 2004:e16.
35. Gabell A, Nayak US. The effect of age on variability in gait. J Gerontol. 1984;39:662-666. (Pubitemid 15180611)
36. Nayak US, Gabell A, Simons MA, Isaacs B. Measurement of gait and balance in the elderly. J Am Geriatr Soc. 1982;30:516-520. (Pubitemid 12061744)
37. Hausdorff JM, Edelberg HK, Mitchell SL, Goldberger AL, Wei JY. Increased gait unsteadiness in community-dwelling elderly fallers. Arch Phys Med Rehabil. 1997;78:278-283. (Pubitemid 27120262)
38. Maki BE. Gait changes in older adults: predictors of falls or indicators of fear. J Am Geriatr Soc. 1997;45:313-320. (Pubitemid 27114304)
39. Brach JS, Berthold R, Craik R, VanSwearingen JM, Newman AB. Gait variability in community-dwelling older adults. J Am Geriatr Soc. 2001;49:1646-1650. (Pubitemid 34007991)
40. Hausdorff JM, Cudkowicz ME, Firtion R, Wei JY, Goldberger AL. Gait variability and basal ganglia disorders: stride-to-stride variations of gait cycle timing in Parkinson's disease and Huntington's disease. Mov Disord. 1998;13:428-437. (Pubitemid 28221494)
41. Huang WN, VanSwearingen JM, Brach JS. Gait variability in older adults: observational rating validated by comparison with a computerized walkway gold standard. Phys Ther. 2008;88:1146-1153.
42. Beauchet O, Dubost V, Herrmann FR, Kressig RW. Stride-to-stride variability while backward counting among healthy young adults. J Neuroengineering Rehabil. 2005;2:26.
43. Beauchet O, Annweiler C, Lecordroch Y, et al. Walking speed-related changes in stride time variability: effects of decreased speed. J Neuroeng Rehabil. 2009;6:32.
44. Rosano C, Brach J, Studenski S, Longstreth WT Jr, Newman AB. Gait variability is associated with subclinical brain vascular abnormalities in high-functioning older adults. Neuroepidemiology. 2007; 29:193-200. (Pubitemid 351197522)
45. Webster KE, Merory JR, Wittwer JE. Gait variability in community dwelling adults with Alzheimer disease. Alzheimer Dis Assoc Disord. 2006;20:37-40. (Pubitemid 44356892)
46. Fitzpatrick AL, Buchanan CK, Nahin RL, et al. Associations of gait speed and other measures of physical function with cognition in a healthy cohort of elderly persons. J Gerontol A Biol Sci Med Sci. 2007;62:1244-1251. (Pubitemid 350287613)
47. Deshpande N, Metter EJ, Bandinelli S, Guralnik J, Ferrucci L. Gait speed under varied challenges and cognitive decline in older persons: a prospective study. Age Ageing. 2009;38:509-514.
48. Ko SU, Hausdorff JM, Ferrucci L. Age-associated differences in the gait pattern changes of older adults during fast-speed and fatigue conditions: results from the Baltimore longitudinal study of ageing. Age Ageing. 2010;39:688-694.
49. Campbell AJ, Buchner DM. Unstable disability and the fuctuations of frailty. Age Ageing. 1997;26:315-318.
50. Chaves PH, Varadhan R, Lipsitz LA, et al. Physiological complexity underlying heart rate dynamics and frailty status in community-dwelling older women. J Am Geriatr Soc. 2008;56:1698-1703.
51. Fried LP, Xue QL, Cappola AR, et al. Nonlinear multisystem physiological dysregulation associated with frailty in older women: implications for etiology and treatment. J Gerontol A Biol Sci Med Sci. 2009; 64:1049-1057.