Quantitative gait markers and incident fall risk in older adults

Journals of Gerontology - Series A Biological Sciences and Medical Sciences

Volumn 64, Issue 8, 2009, Pages 896-901

  Verghese, Joe ^a   Holtzer, Roee ^a,b   Lipton, Richard B ^a   Wang, Cuiling ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b YESHIVA UNIVERSITY   (United States)

Author keywords

Falls; Gait

Indexed keywords

ADULT; AGED; ARTICLE; CADENCE; DISABILITY; DISEASE ASSOCIATION; FALL RISK ASSESSMENT; FALLING; FEMALE; FOLLOW UP; GAIT; GAIT DOUBLE SUPPORT; GAIT SWING; GAIT SWING TIME VARIABILITY; HUMAN; MAJOR CLINICAL STUDY; MALE; MEASUREMENT; PREDICTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; STRIDE LENGTH; STRIDE LENGTH VARIABILITY; TIME; VELOCITY;

ACCIDENTAL FALLS; AGED; AGED, 80 AND OVER; BIOLOGICAL MARKERS; COHORT STUDIES; GAIT; HUMANS; PROSPECTIVE STUDIES; RISK FACTORS;

EID: 67650665072     PISSN: 10795006     EISSN: None     Source Type: Journal    
DOI: 10.1093/gerona/glp033     Document Type: Article

References (42)

1. Sattin RW. Falls among older persons: a public health perspective. Annu Rev Public Health. 1992;13:489-508.
2. Tinetti ME, Williams CS. Falls, injuries due to falls, and the risk of admission to a nursing home. N Engl J Med. 1997;337(18): 1279-1284.
3. Stevens JA, Corso PS, Finkelstein EA, Miller TR. The costs of fatal and non-fatal falls among older adults. Inj Prev. 2006;12(5): 290-295.
4. Verghese J, Buschke H, Viola L, et al. Validity of divided attention tasks in predicting falls in older individuals: a preliminary study [see comment]. J Am Geriatr Soc. 2002;50(9):1572-1576.
5. Ganz DA, Bao Y, Shekelle PG, Rubenstein LZ. Will my patient fall? JAMA. 2007;297(1):77-86.
6. Studenski S, Perera S, Wallace D, et al. Physical performance measures in the clinical setting. J Am Geriatr Soc. 2003;51( 3):314-322.
7. Tinetti ME, Baker DI, McAvay G, et al. A multifactorial intervention to reduce the risk of falling among elderly people living in the community [see comment]. N Engl J Med. 1994;331(13):821-827.
8. American Geriatrics Society BGS and American Academy of Orthopaedic Surgeons Panel on Falls Prevention. Guideline for the prevention of falls in older persons. J Am Geriatr Soc. 2001;49(5):664-672.
9. Tinetti ME, Speechley M, Ginter SF. Risk factors for falls among elderly persons living in the community. N Engl J Med. 1988;319(26):1701-1707.
10. Verghese J, LeValley A, Hall CB, Katz MJ, Ambrose AF, Lipton RB. Epidemiology of gait disorders in community-residing older adults. J Am Geriatr Soc. 2006;54(2):255-261.
11. Verghese J, Kuslansky G, Holtzer R, et al. Walking while talking: effect of task prioritization in the elderly. Arch Phys Med Rehabil. 2007;88(1):50-53.
12. Colon-Emeric C, Schenck A, Gorospe J, et al. Translating evidence-based falls prevention into clinical practice in nursing facilities: results and lessons from a quality improvement collaborative. J Am Geriatr Soc. 2006;54(9):1414-1418.
13. Cesari M, Kritchevsky SB, Penninx BWHJ, et al. Prognostic value of usual gait speed in well-functioning older people-results from the Health, Aging and Body Composition Study. J Am Geriatr Soc. 2005;53(10):1675-1680.
14. Campbell AJ, Borrie MJ, Spears GF. Risk factors for falls in a community-based prospective study of people 70 years and older. J Gerontol. 1989;44(4):M112-M117.
15. Lipsitz LA, Jonsson PV, Kelley MM, Koestner JS. Causes and correlates of recurrent falls in ambulatory frail elderly. J Gerontol. 1991;46(4):M114-M122.
16. Wolfson L, Whipple R, Amerman P, Tobin JN. Gait assessment in the elderly:a gait abnormality rating scale and its relation to falls. J Gerontol. 1990;45(1):M12-M19.
17. Dargent-Molina P, Favier F, Grandjean H, et al. Fall-related factors and risk of hip fracture: the EPIDOS prospective study. Lancet. 1996;348(9021):145-149.
18. Luukinen H, Koski K, Laippala P, Kivela SL. Predictors for recurrent falls among the home-dwelling elderly. Scand J Prim Health Care. 1995;13(4):294-299.
19. Chan BK, Marshall LM, Winters KM, Faulkner KA, Schwartz AV, Orwoll ES. Incident fall risk and physical activity and physical performance among older men: the Osteoporotic Fractures in Men Study. Am J Epidemiol. 2007;165(6):696-703.
20. Hausdorff JM, Rios DA, Edelberg HK. Gait variability and fall risk in community-living older adults: a 1-year prospective study. Arch Phys Med Rehabil. 2001;82(8):1050-1056.
21. Verghese J, Wang C, Lipton RB, Holtzer R, Xue X. Quantitative gait dysfunction and risk of cognitive decline and dementia. J Neurol Neurosurg Psychiatry. 2007;78(9):929-935.
22. Menz HB, Latt MD, Tiedemann A, Mun San Kwan M, Lord SR. Reliability of the GAITRite walkway system for the quantification of temporo-spatial parameters of gait in young and older people. Gait Posture. 2004;20(1):20-25.
23. Yesavage JA, Brink TL, Rose TL, et al. Development and validation of a geriatric depression screening scale:a preliminary report. J Psychiatr Res. 1982;17(1):37-49.
24. Verghese J, Lipton RB, Hall CB, Kuslansky G, Katz MJ, Buschke H. Abnormality of gait as a predictor of non-Alzheimer's dementia. N Engl J Med. 2002;347(22):1761-1768.
25. Holtzer R, Friedman R, Lipton RB, Katz M, Xue X, Verghese J. The relationship between specific cognitive functions and falls in aging. Neuropsychology. 2007;21(5):540-548.
26. Gill TM, Allore HG, Holford TR, Guo Z. Hospitalization, restricted activity, and the development of disability among older persons. JAMA. 2004;292(17):2115-2124.
27. Blessed G, Tomlinson BE, Roth M. The association between quantitative measures of dementia and of senile change in the cerebral grey matter of elderly subjects. Br J Psychiatry. 1968;114(512):797-811.
28. Hurvitz EA, Richardson JK, Werner RA. Unipedal stance testing in the assessment of peripheral neuropathy. Arch Phys Med Rehabil. 2001;82(2):198-204.
29. Zeger SL, Liang KY. Longitudinal data analysis for discrete and continuous outcomes. Biometrics. 1986;42(1):121-130.
30. McCullagh P, Nelder JA. Generalized Linear Models. London, UK: Chapman and Hall;1989.
31. Perera S, Mody SH, Woodman RC, Studenski SA. Meaningful change and responsiveness in common physical performance measures in older adults. J Am Geriatr Soc. 2006;54(5):743-749.
32. Binder EF, Brown M, Sinacore DR, Steger-May K, Yarasheski KE, Schechtman KB. Effects of extended outpatient rehabilitation after hip fracture: a randomized controlled trial. JAMA. 2004;292(7):837-846.
33. Baezner H, Oster M, Henning O, Cohen S, Hennerici MG. Amantadine increases gait steadiness in frontal gait disorder due to subcortical vascular encephalopathy: a double-blind randomized placebo-controlled trial based on quantitative gait analysis. Cerebrovasc Dis. 2001;11(3):235-244.
34. Herman T, Giladi N, Gruendlinger L, Hausdorff JM. Six weeks of intensive treadmill training improves gait and quality of life in patients with Parkinson's disease: a pilot study. Arch Phys Med Rehabil. 2007;88(9):1154-1158.
35. Pan W. Akaike's information criterion in generalized estimating equations. Biometrics. 2001;57(1):120-125.
36. Hartikainen S, Lönnroos E, Louhivuori K. Medication as a risk factor for falls: critical systematic review. J Gerontol A Biol Sci Med Sci. 2007;62(10):1172-1181.
37. Ganz DA, Higashi T, Rubenstein LZ. Monitoring falls in cohort studies of community-dwelling older people: effect of the recall interval. J Am Geriatr Soc. 2005;53(12):2190-2194.
38. Benjamini Y, Hochberg Y. Controlling the false discovery rate: A new and powerful approach to multiple testing. J R Stat Soc. 1995;57: 1289-1300.
39. Maki BE. Gait changes in older adults: predictors of falls or indicators of fear [see comment]. J Am Geriatr Soc. 1997;45(3):313-320.
40. Brach JS, Studenski SA, Perera S, VanSwearingen JM, Newman AB. Gait variability and the risk of incident mobility disability in communitydwelling older adults. J Gerontol A Biol Sci Med Sci. 2007;62(9):983-988.
41. Gabel A, Nayak US. The effect of age on variability in gait. J Gerontol. 1984;39(6):662-666.
42. Rosano C, Brach J, Studenski S, Longstreth WT Jr, Newman AB. Gait variability is associated with subclinical brain vascular abnormalities in high-functioning older adults. Neuroepidemiology. 2007;29(3-4):193-200.