Skeletal myotube integration with planar microelectrode arrays in vitro for spatially selective recording and stimulation: A comparison of neuronal and myotube extracellular action potentials

Biotechnology Progress

Volumn 27, Issue 3, 2011, Pages 891-895

  Langhammer, Christopher G ^a,b   Kutzing, Melinda K ^a,b   Luo, Vincent ^a,b   Zahn, Jeffrey D ^b   Firestein, Bonnie L ^a  

^a RUTGERS UNIVERSITY   (United States)

^b RUTGERS UNIVERSITY   (United States)

Author keywords

Extracellular action potential; Microelectrode array; Myoblast fusion; Skeletal muscle

Indexed keywords

BIODETECTION; BIOLOGICAL SIGNALS; CARDIAC MYOCYTES; CELL TYPES; CELLULAR COMPONENTS; CO-CULTURES; DETECTION TECHNOLOGY; ELECTRICAL INTERACTION; EXTRACELLULAR ACTION POTENTIAL; IN-VITRO; LAB-ON-A-CHIP APPLICATIONS; MICROELECTRODE ARRAY; MOTOR NEURONS; MULTIPLE ELECTRODES; MYOBLASTS; MYOTUBES; NEURAL INTERFACES; NEURAL SPIKE TRAINS; PLANAR MICROELECTRODE ARRAYS; SHAPE BASED; SKELETAL MUSCLE; SPIKE-SORTING;

BIOSENSORS; CELL CULTURE; ELECTROPHYSIOLOGY; MICROELECTRODES; NEURAL NETWORKS; NEURONS; TISSUE; TISSUE ENGINEERING;

MUSCULOSKELETAL SYSTEM;

ACTION POTENTIAL; ANIMAL; ARTICLE; BIOTECHNOLOGY; COMPARATIVE STUDY; ELECTROPHYSIOLOGY; GENETIC PROCEDURES; HUMAN; METHODOLOGY; MICROELECTRODE; MYOBLAST; NERVE CELL; PHYSIOLOGY; SKELETAL MUSCLE; ULTRASTRUCTURE;

ACTION POTENTIALS; ANIMALS; BIOSENSING TECHNIQUES; BIOTECHNOLOGY; ELECTROPHYSIOLOGY; HUMANS; MICROELECTRODES; MUSCLE FIBERS, SKELETAL; MYOBLASTS, SKELETAL; NEURONS;

EID: 79958250590     PISSN: 87567938     EISSN: 15206033     Source Type: Journal    
DOI: 10.1002/btpr.609     Document Type: Article

References (23)

1. Kovacs GTA. Electronic sensors with living cellular components. Proc IEEE. 2003; 91: 915-929.
2. Offenhausser A, Knoll W. Cell-transistor hybrid systems and their potential applications. Trends Biotechnol. 2001; 19: 62-66.
3. Stett A, Egert U, Guenther E, Hofmann F, Meyer T, Nisch W, Haemmerle H. Biological application of microelectrode arrays in drug discovery and basic research. Anal Bioanal Chem. 2003; 377: 486-495.
4. Molnar P, Wang WS, Natarajan A, Rumsey JW, Hickman JJ. Photolithographic patterning of C2C12 myotubes using vitronectin as growth substrate in serum-free medium. Biotechnol Prog. 2007; 23: 265-268.
5. Rich MM. The control of neuromuscular transmission in health and disease. Neuroscientist. 2006; 12: 134-142.
6. Xi JZ, Schmidt JJ, Montemagno CD. Self-assembled microdevices driven by muscle. Nat Mater. 2005; 4: 180-184.
7. Bian WN, Bursac N. Engineered skeletal muscle tissue networks with controllable architecture. Biomaterials. 2009; 30: 1401-1412.
8. Midrio M. The denervated muscle: facts and hypotheses. A historical review. Eur J Appl Physiol. 2006; 98: 1-21.
9. Wilson K, Molnar P, Hickman J. Integration of functional myotubes with a Bio-MEMS device for non-invasive interrogation. Lab Chip. 2007; 7: 920-922.
10. Langhammer CG, Zahn JD, Firestein BL. Identification and quantification of skeletal myotube contraction and association in vitro by video microscopy. Cytoskeleton. 2010.
11. Charych EI, Akum BF, Goldberg JS, Jörnsten RJ, Rongo C, Zheng JQ, Firestein BL. Activity-independent regulation of dendrite patterning by postsynaptic density protein PSD-95. J Neurosci. 2006; 26: 10164-10176.
12. Adamos DA, Kosmidis EK, Neophilidis G. Performance evaluation of PCA-based spike sorting algorithms. Comput Methods Programs Biomed. 2008; 91: 232-244.
13. Bove M, Grattarola M, Martinoia S, Verreschi G. Interfacing cultured neurons to planar substrate microelectrodes-characterization of the neuron-to-microelectrode junction. Bioelectrochem Bioenerg. 1995; 38: 255-265.
14. Gold C, Henze DA, Koch C, Buzsaki G. On the origin of the extracellular action potential waveform: a modeling study. J Neurophysiol. 2006; 95: 3113-3128.
15. Dworak BJ, Wheeler BC. Novel MEA platform with PDMS microtunnels enables the detection of action potential propagation from isolated axons in culture. Lab Chip. 2009; 9: 404-410.
16. Jenerick H. An analysis of the striated muscle fiber action current. Biophys J. 1964; 4: 77-91.
17. Dimitrov GV, Dimitrova NA. Precise and fast calculation of the motor unit potentials detected by a point and rectangular plate electrode. Med Eng Phys. 1998; 20: 374-381.
18. Hammarberg B, Stalberg E. Novel ideas for fast muscle action potential simulations using the line source model. IEEE Trans Biomed Eng. 2004; 51: 1888-1897.
19. Buitenweg J, Rutten W, Marani E. Geometry-based finite-element modeling of the electrical contact between a cultured neuron and a microelectrode. IEEE Trans Biomed Eng. 2003; 50: 501-509.
20. Clark P, Dunn GA, Knibbs A, Peckham M., Alignment of myoblasts on ultrafine gratings inhibits fusion in vitro. Int J Biochem Cell Biol. 2002; 34: 816-825.
21. Egeland BM, Urbanchek M, Martin DC, Kipke DR, Kuzon WJr, Cederna PS. Engineering and development of a stable, low-impedance, bioelectrical peripheral nerve interface. J Am Coll Surg. 2009; 209: S76-S76.
22. Kuiken TA. Consideration of nerve-muscle grafts to improve the control of artificial arms. J Technol Disabil. 2003; 15: 105-111.
23. Kuiken TA, Li G, Lock BA, Lipschutz RD, Miller LA, Stubblefield KA, Englehart KB. Targeted muscle reinnervation for real-time myoelectric control of multifunction artificial arms. JAMA. 2009; 301: 619-628.