TGF-β1 and BRCA2 Expression are Associated with Clinical Factors in Breast Cancer

Cell Biochemistry and Biophysics

Volumn 60, Issue 3, 2011, Pages 245-248

  Li, Junchuan ^a   Zhu, Hongyu ^a   Chen, Tingxuan ^a   Dai, Guihua ^a   Zou, Lanying ^a  

^a YANGTZE UNIVERSITY   (China)

Author keywords

BRCA2; Breast cancer genetics; HER2; TGF

Indexed keywords

BRCA2 PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; PROGESTERONE RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1;

ADULT; AGE; AGED; ARTICLE; BREAST TUMOR; CANCER STAGING; FEMALE; HUMAN; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; METABOLISM; MIDDLE AGED; PATHOLOGY;

ADULT; AGE FACTORS; AGED; BRCA2 PROTEIN; BREAST NEOPLASMS; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LYMPHATIC METASTASIS; MIDDLE AGED; NEOPLASM STAGING; RECEPTOR, ERBB-2; RECEPTORS, ESTROGEN; RECEPTORS, PROGESTERONE; TRANSFORMING GROWTH FACTOR BETA1;

EID: 79958248565     PISSN: 10859195     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12013-010-9146-4     Document Type: Article

References (14)

1. Todorovic-Rakovic, N. (2005). TGF-beta 1 could be a missing link in the interplay between ER and HER-2 in breast cancer. Medical Hypotheses, 65, 546-551.
2. Mobus, V. J., Moll, R., Gerharz, C. D., Kieback, D. G., Merk, O., et al. (1998). Differential characteristics of two new tumorigenic cell lines of human breast carcinoma origin. International Journal of Cancer, 77, 415-423.
3. Kidd, L. R., Brock, G. N., VanCleave, T. T., Benford, M. L., Lavender, N. A., et al. (2010). Angiogenesis-associated sequence variants relative to breast cancer recurrence and survival. Cancer Causes and Control, 21, 1545-1557.
4. Bornstein, S., White, R., Malkoski, S., Oka, M., Han, G., et al. (2009). Smad4 loss in mice causes spontaneous head and neck cancer with increased genomic instability and inflammation. Journal of Clinical Investigation, 119, 3408-3419.
5. Hueman, M. T., Stojadinovic, A., Storrer, C. E., Foley, R. J., Gurney, J. M., et al. (2006). Levels of circulating regulatory CD4 + CD25 + T cells are decreased in breast cancer patients after vaccination with a HER2/neu peptide (E75) and GM-CSF vaccine. Breast Cancer Research and Treatment, 98, 17-29.
6. Kokkinakis, D. M., Liu, X., Chada, S., Ahmed, M. M., Shareef, M. M., et al. (2004). Modulation of gene expression in human central nervous system tumors under methionine deprivation-induced stress. Cancer Research, 64, 7513-7525.
7. Yang, D. C., Elliott, R. L., & Head, J. F. (2002). Gene targets of antisense therapies in breast cancer. Expert Opinion on Therapeutic Targets, 6, 375-385.
8. Tamura, J., Nakamura-Yamamoto, T., Nishimura, Y., Mizumoto, S., Takahashi, J., et al. (2010). Synthesis of the glycosaminoglycan-protein linkage tetraosyl peptide moieties of betaglycan, which serve as a hexosamine acceptor for enzymatic glycosyl transfer. Carbohydrate Research, 345, 2115-2123.
9. Chenevix-Trench, G., Milne, R. L., Antoniou, A. C., Couch, F. J., Easton, D. F., et al. (2007). An international initiative to identify genetic modifiers of cancer risk in BRCA1 and BRCA2 mutation carriers: The Consortium of Investigators of Modifiers of BRCA1 and BRCA2 (CIMBA). Breast Cancer Research, 9, p. 104.
10. Powell, W. C., Hicks, D. G., Prescott, N., Tarr, S. M., Laniauskas, S., et al. (2007). A new rabbit monoclonal antibody (4B5) for the immunohistochemical (IHC) determination of the HER2 status in breast cancer: Comparison with CB11, fluorescence in situ hybridization (FISH), and interlaboratory reproducibility. Applied Immunohistochemistry Molecular Morphology, 15, 94-102.
11. Zhu, L., Loo, W. T., Cheng, C. W., & Chow, L. W. (2006). Possible predictive markers related to micro-metastasis in breast cancer patients. Oncology Reports, 15, 1217-1223.
12. Kim, S. J., Park, J. H., Kim, K. H., Lee, W. R., Chang, Y. C., et al. (2010). Bee venom inhibits hepatic fibrosis through suppression of pro-fibrogenic cytokine expression. American Journal of Chinese Medicine, 38, 921-935.
13. Song, C. G., Hu, Z., Yuan, W. T., Di, G. H., Shen, Z. Z., et al. (2006). BRCA1 and BRCA2 gene mutations of familial breast cancer from Shanghai in China. Zhonghua Yi Xue Yi Chuan Xue Za Zhi, 23, 27-31.
14. Antoniou, A. C., Goldgar, D. E., Andrieu, N., Chang-Claude, J., Brohet, R., et al. (2005). A weighted cohort approach for analysing factors modifying disease risks in carriers of high-risk susceptibility genes. Genetic Epidemiology, 29, 1-11.