A transcriptome signature distinguished sporadic from postradiotherapy radiation-induced sarcomas

Carcinogenesis

Volumn 32, Issue 6, 2011, Pages 929-934

  Hadj Hamou, Nabila Sandra ^a,b,c   Ugolin, Nicolas ^d   Ory, Catherine ^d   Britzen Laurent, Nathalie ^a,b,c,e   Sastre Garau, Xavier ^a   Chevillard, Sylvie ^d   Malfoy, Bernard ^a,b,c  

^a INSTITUT CURIE   (France)

^b Institut Curie   (France)

^c SORBONNE UNIVERSITÉ   (France)

^d INSTITUT DE RADIOBIOLOGIE CELLULAIRE ET MOLÉCULAIRE   (France)

^e UNIVERSITY HOSPITAL ERLANGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTOME;

ANGIOSARCOMA; ARTICLE; CANCER RADIOTHERAPY; GENE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; LEIOMYOSARCOMA; OSTEOSARCOMA; OXIDATIVE STRESS; PRIMARY TUMOR; PRIORITY JOURNAL; RADIATION INDUCED NEOPLASM; SARCOMA;

EID: 79958204019     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgr064     Document Type: Article

References (31)

1. Suit,H. et al. (2007) Secondary carcinogenesis in patients treated with radiation: a review of data on radiation-induced cancers in human, nonhuman primate, canine and rodent subjects. Radiat. Res., 167, 12-42.
2. Williams,E.D. (2006) Chernobyl and thyroid cancer. J. Surg. Oncol., 94, 670-677.
3. Williams,E.D. et al. (2004) Thyroid carcinoma after Chernobyl latent period, morphology and aggressiveness. Br. J. Cancer, 90, 2219-2224.
4. Powell,N. et al. (2005) Frequency of BRAF T1796A mutation in papillary thyroid carcinoma relates to age of patient at diagnosis and not to radiation exposure. J. Pathol., 205, 558-564.
5. Kimmel,R.R. et al. (2006) Microarray comparative genomic hybridization reveals genome-wide patterns of DNA gains and losses in post-Chernobyl thyroid cancer. Radiat. Res., 166, 519-531.
6. Detours,V. et al. (2005) Absence of a specific radiation signature in post-Chernobyl thyroid cancers. Br. J. Cancer, 92, 1545-1552.
7. Detours,V. et al. (2007) Genome-wide gene expression profiling suggests distinct radiation susceptibilities in sporadic and post-Chernobyl papillary thyroid cancers. Br. J. Cancer, 97, 818-825.
8. Boltze,C. et al. (2009) Sporadic and radiation-associated papillary thyroid cancers can be distinguished using routine immunohistochemistry. Oncol. Rep., 22, 459-467.
9. Gonin-Laurent,N. et al. (2006) Specific TP53 mutation pattern in radiationinduced sarcomas. Carcinogenesis, 27, 1266-1272.
10. Broeks,A. et al. (2010) Radiation-associated breast tumors display a distinct gene expression profile. Int. J. Radiat. Oncol. Biol. Phys., 76, 540-547.
11. Chevillard,S. et al. (2004) Gene expression profiling of differentiated thyroid neoplasms: diagnostic and clinical implications. Clin. Cancer Res., 10, 6586-6597.
12. Daino,K. et al. (2009) Silencing of Cited2 and Akap12 genes in radiation-induced rat osteosarcomas. Biochem. Biophys. Res. Commun., 390, 654-658.
13. Bastide,K. et al. (2009) Are adenosquamous lung carcinomas a simple mix of adenocarcinomas and squamous cell carcinomas, or more complex at the molecular level? Lung Cancer, 63, 348-353.
14. Ory,C. et al. (2011) Gene expression signature discriminates sporadic from post-radiotherapy-induced thyroid tumors. Endocr. Relat. Cancer, 18, 193-206.
15. Gonin-Laurent,N. et al. (2007) RB1 and TP53 pathways in radiationinduced sarcomas. Oncogene, 26, 6106-6112.
16. Cahan,W.G. et al. (1948) Sarcoma arising in irradiated bone. Cancer, 1, 3-29.
17. Le Brigand,K. et al. (2006) An open-access long oligonucleotide microarray resource for analysis of the human and mouse transcriptomes. Nucleic Acids Res., 34, e87.
18. Clark,M.A. et al. (2005) Soft-tissue sarcomas in adults. N. Engl. J. Med., 353, 701-711.
19. Huvos,A.G. et al. (1985) Postradiation osteogenic sarcoma of bone and soft tissues. A clinicopathologic study of 66 patients. Cancer, 55, 1244-1255.
20. Lagrange,J.L. et al. (2000) Sarcoma after radiation therapy: retrospective multiinstitutional study of 80 histologically confirmed cases. Radiation Therapist and Pathologist Groups of the Federation Nationale des Centres de Lutte Contre le Cancer. Radiology, 216, 197-205.
21. Penel,N. et al. (2008) Frequency of certain established risk factors in soft tissue sarcomas in adults: a prospective descriptive study of 658 cases. Sarcoma, 2008, 459386.
22. Jung,T. et al. (2009) The proteasomal system. Mol. Aspects Med., 30, 191-296.
23. Reyes-Turcu,F.E. et al. (2009) Regulation and cellular roles of ubiquitinspecific deubiquitinating enzymes. Annu. Rev. Biochem., 78, 363-397.
24. Robbins,M.E. et al. (2002) Radiation-induced kidney injury: a role for chronic oxidative stress? Micron, 33, 133-141.
25. Fleckenstein,K. et al. (2007) Temporal onset of hypoxia and oxidative stress after pulmonary irradiation. Int. J. Radiat. Oncol. Biol. Phys., 68, 196-204.
26. Jack,C.I. et al. (1996) Indicators of free radical activity in patients developing radiation pneumonitis. Int. J. Radiat. Oncol. Biol. Phys., 34, 149-154.
27. Beinert,T. et al. (1999) Oxidant-induced lung injury in anticancer therapy. Eur. J. Med. Res., 4, 43-53.
28. Rzeszowska-Wolny,J. et al. (2009) Ionizing radiation-induced bystander effects, potential targets for modulation of radiotherapy. Eur. J. Pharmacol., 625, 156-164.
29. Prise,K.M. et al. (2009) Radiation-induced bystander signalling in cancer therapy. Nat. Rev. Cancer, 9, 351-360.
30. Kim,G.J. et al. (2006) A role for mitochondrial dysfunction in perpetuating radiation-induced genomic instability. Cancer Res., 66, 10377-10383.
31. Port,M. et al. (2007) A radiation-induced gene signature distinguishes post-Chernobyl from sporadic papillary thyroid cancers. Radiat. Res., 168, 639-649.