Jury remains out on simple models of transcription factor specificity

Nature Biotechnology

Volumn 29, Issue 6, 2011, Pages 483-484

  Morris, Quaid ^a,b   Bulyk, Martha L ^c,d,e   Hughes, Timothy R ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d HARVARD MIT DIVISION OF HEALTH SCIENCES AND TECHNOLOGY   (United States)

^e HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR; ZINC FINGER PROTEIN;

BINDING AFFINITY; LETTER; MODEL; POSITION WEIGHT MATRIX; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN MICROARRAY;

HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; MODELS, MOLECULAR; TRANSCRIPTION FACTORS;

EID: 79958153978     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt.1892     Document Type: Letter

References (6)

1. Zhao, Y. & Stormo, G.D. Nat. Biotechnol. 29, 480-483 (2011).
2. Badis, G. et al. Science 324, 1720-1723 (2009).
3. Chen, X., Hughes, T.R. & Morris, Q. Bioinformatics 23, i72-i79 (2007).
4. Zhao, Y., Granas, D. & Stormo, G.D. PLoS Comput. Biol. 5, e1000590 (2009).
5. Johnson, D.S., Mortazavi, A., Myers, R.M. & Wold, B. Science 316, 1497-1502 (2007).
6. Berger, M.F. et al. Nat. Biotechnol. 24, 1429-1435 (2006).