Genetic association between BDNF gene polymorphisms and phobic disorders: A case-control study among mainland Han Chinese

Journal of Affective Disorders

Volumn 132, Issue 1-2, 2011, Pages 239-242

  Xie, Bing ^a   Wang, Binbin ^b,c   Suo, Peisu ^b,c   Kou, Changgui ^a   Wang, Jing ^b,c   Meng, Xiangfei ^a   Cheng, Longfei ^b,c   Ma, Xu ^b,c,d   Yu, Yaqin ^a,c  

^a JILIN UNIVERSITY   (China)

^b GRADUATE SCHOOL OF PEKING UNION MEDICAL COLLEGE   (China)

^c NATIONAL RESEARCH INSTITUTE FOR FAMILY PLANNING   (China)

^d WORLD HEALTH ORGANIZATION   (Switzerland)

Author keywords

Association study; BDNF; Phobic disorder; Tag SNP

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR;

ADULT; ARTICLE; CASE CONTROL STUDY; CHINESE; CONTROLLED STUDY; FEMALE; GENE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC LINKAGE; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HEALTH SURVEY; HUMAN; MAJOR CLINICAL STUDY; MALE; PHOBIA; POLYMERASE CHAIN REACTION; POLYMERASE CHAIN REACTION LIGASE DETECTION REACTION; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

ALLELES; ASIAN CONTINENTAL ANCESTRY GROUP; BRAIN-DERIVED NEUROTROPHIC FACTOR; CASE-CONTROL STUDIES; CHINA; GENETIC ASSOCIATION STUDIES; GENETICS, POPULATION; GENOTYPE; HUMANS; PERSONALITY ASSESSMENT; PHOBIC DISORDERS; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE; PSYCHOMETRICS; YOUNG ADULT;

EID: 79958149370     PISSN: 01650327     EISSN: 15732517     Source Type: Journal    
DOI: 10.1016/j.jad.2010.12.017     Document Type: Article

References (20)

1. P. Alonso, M. Gratacos, J.M. Menchon, J. Saiz-Ruiz, C. Segalas, and E. Baca-Garcia Extensive genotyping of the BDNF and NTRK2 genes define protective haplotypes against obsessive-compulsive disorder Biol. Psychiatry 63 2008 619 628 (Pubitemid 351273192)
2. P.D. Arnold, G. Zai, and M.A. Richter Genetics of anxiety disorders Curr. Psychiatry Rep. 6 2004 243 254 (Pubitemid 39173539)
3. J.C. Barrett, B. Fry, J. Maller, and M.J. Daly Haploview: analysis and visualization of LD and haplotype maps Bioinformatics 21 2005 263 265 (Pubitemid 40202029)
4. Z.Y. Chen, D. Jing, K.G. Bath, A. Ieraci, T. Khan, and C.J. Siao Genetic variant BDNF (Val66Met) polymorphism alters anxiety-related behavior Science 314 2006 140 143 (Pubitemid 44547760)
5. F. Dudbridge Pedigree disequilibrium tests for multilocus haplotypes Genet. Epidemiol. 25 2003 115 121 (Pubitemid 37064867)
6. A. Frustaci, G. Pozzi, F. Gianfagna, L. Manzoli, and S. Boccia Meta-analysis of the brain-derived neurotrophic factor gene (BDNF) Val66Met polymorphism in anxiety disorders and anxiety-related personality traits Neuropsychobiology 58 2008 163 170
7. J. Gelernter, G.P. Page, K. Bonvicini, S.W. Woods, D.L. Pauls, and S. Kruger A chromosome 14 risk locus for simple phobia: results from a genome-wide linkage scan Mol. Psychiatry 8 2003 71 82 (Pubitemid 36188575)
8. K. Hashimoto BDNF variant linked to anxiety-related behaviors Bioessays 29 2007 116 119 (Pubitemid 46340246)
9. J.M. Hettema, C.A. Prescott, and K.S. Kendler A population-based twin study of generalized anxiety disorder in men and women J. Nerv. Ment. Dis. 189 2001 413 420 (Pubitemid 32730203)
10. H. Katerberg, C. Lochner, D.C. Cath, P. de Jonge, Z. Bochdanovits, and J.C. Moolman-Smook The role of the brain-derived neurotrophic factor (BDNF) val66met variant in the phenotypic expression of obsessive-compulsive disorder (OCD) Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B 2009 1050 1062
11. K.S. Kendler, L.M. Karkowski, and C.A. Prescott Fears and phobias: reliability and heritability Psychol. Med. 29 1999 539 553 (Pubitemid 29261343)
12. R.C. Kessler, and T.B. Ustun The World Mental Health (WMH) survey initiative version of the World Health Organization (WHO) Composite International Diagnostic Interview (CIDI) Int. J. Meth. Psychiatr. Res. 13 2004 93 121
13. K. Kobayashi, E. Shimizu, K. Hashimoto, M. Mitsumori, K. Koike, and N. Okamura Serum brain-derived neurotrophic factor (BDNF) levels in patients with panic disorder: as a biological predictor of response to group cognitive behavioral therapy Prog. Neuropsychopharmacol. Biol. Psychiatry 29 2005 658 663 (Pubitemid 40897773)
14. N. Kozlovsky, M.A. Matar, Z. Kaplan, M. Kotler, J. Zohar, and H. Cohen Long-term down-regulation of BDNF mRNA in rat hippocampal CA1 subregion correlates with PTSD-like behavioural stress response Int. J. Neuropsychopharmacol. 10 2007 741 758 (Pubitemid 350035829)
15. W.J. Magee, W.W. Eaton, H.U. Wittchen, K.A. McGonagle, and R.C. Kessler Agoraphobia, simple phobia, and social phobia in the National Comorbidity Survey Arch. Gen. Psychiatry 53 1996 159 168 (Pubitemid 26049391)
16. S.C. Pandey, H. Zhang, A. Roy, and K. Misra Central and medial amygdaloid brain-derived neurotrophic factor signaling plays a critical role in alcohol-drinking and anxiety-like behaviors J. Neurosci. 26 2006 8320 8331 (Pubitemid 44309846)
17. J.W. Smoller, E. Gardner-Schuster, and J. Covino The genetic basis of panic and phobic anxiety disorders Am. J. Med. Genet. C Semin. Med. Genet. 148C 2008 118 126 (Pubitemid 351705128)
18. F. Soliman, C.E. Glatt, K.G. Bath, L. Levita, R.M. Jones, and S.S. Pattwell A genetic variant BDNF polymorphism alters extinction learning in both mouse and human Science 327 2010 863 866
19. M.B. Stein, M.J. Chartier, A.L. Hazen, M.V. Kozak, M.E. Tancer, and S. Lander A direct-interview family study of generalized social phobia Am. J. Psychiatry 155 1998 90 97 (Pubitemid 28037554)
20. H. Zhang, F. Ozbay, J. Lappalainen, H.R. Kranzler, C.H. van Dyck, and D.S. Charney Brain derived neurotrophic factor (BDNF) gene variants and Alzheimer's disease, affective disorders, posttraumatic stress disorder, schizophrenia, and substance dependence Am. J. Med. Genet. B Neuropsychiatr. Genet. 141B 2006 387 393 (Pubitemid 43872891)